ES460387A1 - Un procedimiento para la preparacion de un isomero optico deun compuesto de hexahidrodibenzopiranona. - Google Patents

Un procedimiento para la preparacion de un isomero optico deun compuesto de hexahidrodibenzopiranona.

Info

Publication number
ES460387A1
ES460387A1 ES460387A ES460387A ES460387A1 ES 460387 A1 ES460387 A1 ES 460387A1 ES 460387 A ES460387 A ES 460387A ES 460387 A ES460387 A ES 460387A ES 460387 A1 ES460387 A1 ES 460387A1
Authority
ES
Spain
Prior art keywords
hexahydro
dimethyl
optically active
substituted
dibenzopyranones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES460387A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES460387A1 publication Critical patent/ES460387A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Saccharide Compounds (AREA)

Abstract

Un procedimiento para la preparación de un isómero óptico de un compuesto de hexahidrodibenzopiranona de fórmula: **ver imagen I** donde los átomos de hidrógeno en la posiciones 6ª y 10ª pueden estar en configuración cis o trans y R4 es alquilo C5-C10, alquenilo C5-C10, cicloalquilo C5-C8 o cicloalquenilo C5-C8., cuyo procedimiento se caracteriza por hacer reaccionar con un ácido un compuesto óptimamente activo.
ES460387A 1976-11-10 1977-07-04 Un procedimiento para la preparacion de un isomero optico deun compuesto de hexahidrodibenzopiranona. Expired ES460387A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/740,502 US4102902A (en) 1976-11-10 1976-11-10 Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor

Publications (1)

Publication Number Publication Date
ES460387A1 true ES460387A1 (es) 1978-04-01

Family

ID=24976773

Family Applications (3)

Application Number Title Priority Date Filing Date
ES460388A Expired ES460388A1 (es) 1976-11-10 1977-07-04 Un procedimiento para la preparacion de derivados opticamen-te activos de 2-norpinanona.
ES460389A Expired ES460389A1 (es) 1976-11-10 1977-07-04 Un procedimiento para la preparacion de un compuesto de nor-pineno opticamente activo.
ES460387A Expired ES460387A1 (es) 1976-11-10 1977-07-04 Un procedimiento para la preparacion de un isomero optico deun compuesto de hexahidrodibenzopiranona.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES460388A Expired ES460388A1 (es) 1976-11-10 1977-07-04 Un procedimiento para la preparacion de derivados opticamen-te activos de 2-norpinanona.
ES460389A Expired ES460389A1 (es) 1976-11-10 1977-07-04 Un procedimiento para la preparacion de un compuesto de nor-pineno opticamente activo.

Country Status (30)

Country Link
US (1) US4102902A (es)
JP (2) JPS5925792B2 (es)
AT (1) AT356103B (es)
AU (1) AU509355B2 (es)
BE (1) BE856413A (es)
BG (2) BG28061A3 (es)
CA (1) CA1101875A (es)
CH (2) CH632506A5 (es)
CS (1) CS196376B2 (es)
DD (2) DD134350A5 (es)
DE (3) DE2760005C2 (es)
DK (1) DK301477A (es)
ES (3) ES460388A1 (es)
FR (1) FR2370742A1 (es)
GB (2) GB1584181A (es)
GR (1) GR66417B (es)
HU (2) HU177308B (es)
IE (1) IE45247B1 (es)
IL (3) IL52427A (es)
MX (1) MX5172E (es)
NL (1) NL7707467A (es)
NZ (1) NZ184526A (es)
PH (3) PH13827A (es)
PL (2) PL104432B1 (es)
PT (1) PT66746B (es)
RO (1) RO78780A (es)
SE (3) SE428020B (es)
SU (2) SU786898A3 (es)
YU (1) YU163677A (es)
ZA (1) ZA773960B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL55274A (en) * 1978-08-02 1982-08-31 Yissum Res Dev Co 4-(2,6-dihydroxy-4-(dimethylheptyl)phenyl)substituted 2-pinen-10-ol and pinane derivatives,their preparation and pharmaceutical compositions comprising them
US4851586A (en) * 1985-09-20 1989-07-25 The Upjohn Company 1,4-naphthalenediol and 1,4-hydroquinone derivatives
US4939169A (en) * 1985-09-20 1990-07-03 The Upjohn Company 1,4-naphthalenediol and 1,4-hydroquinone derivatives
IL80411A (en) * 1986-10-24 1991-08-16 Raphael Mechoulam Preparation of dibenzopyranol derivatives and pharmaceutical compositions containing them
JPH0315035A (ja) * 1989-03-03 1991-01-23 Konica Corp カメラ
JP2577671B2 (ja) * 1990-06-11 1997-02-05 高砂熱学工業株式会社 気化式精密加湿装置
DE69910373T2 (de) * 1998-05-04 2004-04-01 The University Of Connecticut, Farmington Analgetische und immunomodulierende cannabinoiden
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US6900236B1 (en) * 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
WO2001028329A1 (en) 1999-10-18 2001-04-26 University Of Connecticut Peripheral cannabinoid receptor (cb2) selective ligands
MXPA02005104A (es) * 1999-10-18 2003-09-25 Alexipharma Inc Agonistas novedosos de canabinoide biciclico para el receptor canabinoide.
WO2002058636A2 (en) * 2001-01-26 2002-08-01 University Of Connecticut Novel cannabimimetic ligands
WO2002060447A1 (en) 2001-01-29 2002-08-08 University Of Connecticut Receptor selective cannabimimetic aminoalkylindoles
EP1414775B1 (en) * 2001-07-13 2012-12-19 The University of Connecticut Bicyclic cannabinoid
CA2464333C (en) * 2001-10-26 2011-07-26 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
AU2002326312A1 (en) * 2002-04-25 2003-11-10 Virginia Commonwealth University Cannabinoids
US7183313B2 (en) 2002-08-23 2007-02-27 University Of Connecticut Keto cannabinoids with therapeutic indications
AU2006297300B2 (en) * 2005-09-29 2012-05-10 Albany Molecular Research, Inc. Process for production of delta-9-tetrahydrocannabinol
US9763894B2 (en) * 2006-12-05 2017-09-19 Virginia Commonwealth University Inflammation therapy
PL222532B1 (pl) 2012-04-05 2016-08-31 Akademia Morska W Szczecinie Sposób i układ do diagnozowania układu wtryskowego silników o zapłonie samoczynnym, zwłaszcza silników okrętowych
US12029718B2 (en) 2021-11-09 2024-07-09 Cct Sciences, Llc Process for production of essentially pure delta-9-tetrahydrocannabinol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856822A (en) * 1973-07-18 1974-12-24 Smithkline Corp 3-alkenyl dibenzo (b,d)pyrans
US3856820A (en) * 1973-07-18 1974-12-24 Smithkline Corp 2-AMINOMETHYL DIBENZO (b,d) PYRANS
US3856821A (en) * 1973-07-18 1974-12-24 Smithkline Corp ALKOXY DIBENZO (b,d) PYRANS
US3928598A (en) * 1973-11-05 1975-12-23 Lilly Co Eli Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug

Also Published As

Publication number Publication date
ES460389A1 (es) 1978-04-16
HU183286B (en) 1984-04-28
PT66746B (en) 1978-11-27
IL60589A0 (en) 1980-09-16
SE7707633L (sv) 1978-05-11
IE45247L (en) 1978-05-10
GB1584181A (en) 1981-02-11
YU163677A (en) 1982-10-31
CH632481A5 (de) 1982-10-15
SE8005316L (sv) 1980-07-22
PL104432B1 (pl) 1979-08-31
ES460388A1 (es) 1978-04-01
AU2668477A (en) 1979-01-04
BG28411A4 (en) 1980-04-15
SU1128829A3 (ru) 1984-12-07
FR2370742A1 (fr) 1978-06-09
IL60590A0 (en) 1980-09-16
DD134350A5 (de) 1979-02-21
CA1101875A (en) 1981-05-26
DE2729859A1 (de) 1978-05-11
BG28061A3 (en) 1980-02-25
DK301477A (da) 1978-05-11
PL104356B1 (pl) 1979-08-31
BE856413A (fr) 1978-01-04
JPS5359670A (en) 1978-05-29
SE434510B (sv) 1984-07-30
RO78780A (ro) 1982-04-12
AU509355B2 (en) 1980-05-08
SE428020B (sv) 1983-05-30
JPS5865244A (ja) 1983-04-18
FR2370742B1 (es) 1980-12-26
SE8005314L (sv) 1980-07-22
DE2760006C2 (de) 1985-07-04
DE2760005C2 (de) 1984-04-26
PH13890A (en) 1980-10-27
GB1584182A (en) 1981-02-11
ZA773960B (en) 1979-02-28
IE45247B1 (en) 1982-07-14
ATA483677A (de) 1979-09-15
AT356103B (de) 1980-04-10
PL199362A1 (pl) 1978-05-22
PH13827A (en) 1980-10-07
DE2729859C2 (de) 1984-08-23
NL7707467A (nl) 1978-05-12
HU177308B (en) 1981-09-28
IL52427A0 (en) 1977-08-31
MX5172E (es) 1983-04-18
GR66417B (es) 1981-03-20
IL52427A (en) 1981-10-30
DD140455A5 (de) 1980-03-05
SU786898A3 (ru) 1980-12-07
JPS5912654B2 (ja) 1984-03-24
CH632506A5 (de) 1982-10-15
PH14708A (en) 1981-11-13
JPS5925792B2 (ja) 1984-06-21
NZ184526A (en) 1979-03-16
PT66746A (en) 1977-07-01
CS196376B2 (en) 1980-03-31
US4102902A (en) 1978-07-25

Similar Documents

Publication Publication Date Title
ES460387A1 (es) Un procedimiento para la preparacion de un isomero optico deun compuesto de hexahidrodibenzopiranona.
ES8305418A1 (es) Un procedimiento para la preparacion de una nueva serie de macrolidas de la familia c-076-.
GEP19960642B (en) Method of acylated diketonic compounds preparation
ES430277A1 (es) Procedimiento para preparar s-triazolpiridazinas.
GB1222288A (en) Hexahydro-indane and decahydro-naphthalene derivatives
IL66151A (en) Preparation of optically pure d-or l-lactic acid by fermentation
IT7829922A0 (it) Procedimento per la produzione dell'antibiotico ottenuto coltivando un microorganismo del genere nocardia
FR2458533B1 (es)
AU524197B2 (en) Production of fuel alcohol
IT7823198A0 (it) Procedimento per la preparazione di esteri benzilici dell'acido vinil-cliclopropan-carbossilico sostituiti.
AU516280B2 (en) Production of carbon fibres
GB1475478A (en) Multimode light guide
ZA802405B (en) Substituted styrylcyclopropanecarboxylic acid esters, procss for their preparation and their use as insecticides and acaricides
ATE82291T1 (de) Clavamderivate, herstellung und zwischenprodukte.
IT1089421B (it) Procedimento per la produzione di luoruro acido fluorurato avente un gruppo estere
IT7829921A0 (it) Procedimento per la produzione dell'antibiotico ottenuto coltivando un microorganismo del genere nocardia
IT7848936A0 (it) Procedimento per l'ossidazione di butano ad acido acetico
SE8302517D0 (sv) Forfarande for framstellning av antibiotikum c-15003 p-0 (maytansinol)
IT1190399B (it) Processo per la preparazione di composti carbonilici otticamente attivi
DE3572965D1 (en) Process for the production of optically active quinone derivatives
JPS5416442A (en) Optical resolution of 3-pheoxymandelic acid
AU536185B2 (en) 10-bromosandwicine and 10-bromoisosandwicine
ES8207140A1 (es) Un procedimiento para preparar esteres de pirrol .
SU1467956A1 (ru) Метиловый эфир 2-дифенилметилиденгидразино-4-оксо-4-п-толил-2-бутеновой кислоты, проявляющий антидепрессивную активность
IT7820725A0 (it) Esteri dell'acido ciclopropancarbossilico.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202