CO7061068A2 - Derivados de polimixina - Google Patents

Derivados de polimixina

Info

Publication number
CO7061068A2
CO7061068A2 CO14128978A CO14128978A CO7061068A2 CO 7061068 A2 CO7061068 A2 CO 7061068A2 CO 14128978 A CO14128978 A CO 14128978A CO 14128978 A CO14128978 A CO 14128978A CO 7061068 A2 CO7061068 A2 CO 7061068A2
Authority
CO
Colombia
Prior art keywords
polymyxin derivatives
polymyxin
derivatives
Prior art date
Application number
CO14128978A
Other languages
English (en)
Spanish (es)
Inventor
Mona Saadi
Esther Duperchy
Pamela Brown
Michael John Dawson
Sjoerd Nicolaas Wadman
Original Assignee
Novacta Biosystems Ltd
Cantab Anti Infectives Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novacta Biosystems Ltd, Cantab Anti Infectives Ltd filed Critical Novacta Biosystems Ltd
Publication of CO7061068A2 publication Critical patent/CO7061068A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CO14128978A 2011-11-18 2014-06-13 Derivados de polimixina CO7061068A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161561361P 2011-11-18 2011-11-18

Publications (1)

Publication Number Publication Date
CO7061068A2 true CO7061068A2 (es) 2014-09-19

Family

ID=47297320

Family Applications (1)

Application Number Title Priority Date Filing Date
CO14128978A CO7061068A2 (es) 2011-11-18 2014-06-13 Derivados de polimixina

Country Status (15)

Country Link
US (1) US9234006B2 (OSRAM)
EP (1) EP2780357A1 (OSRAM)
JP (1) JP6185920B2 (OSRAM)
KR (1) KR20140091724A (OSRAM)
CN (1) CN103946233A (OSRAM)
AU (1) AU2012338571B2 (OSRAM)
BR (1) BR112014012016A2 (OSRAM)
CA (1) CA2855916A1 (OSRAM)
CO (1) CO7061068A2 (OSRAM)
EA (1) EA024792B1 (OSRAM)
IL (1) IL232278A0 (OSRAM)
MX (1) MX355217B (OSRAM)
SG (1) SG11201402390PA (OSRAM)
TW (1) TWI608019B (OSRAM)
WO (1) WO2013072695A1 (OSRAM)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2855916A1 (en) 2011-11-18 2013-05-23 Novacta Biosystems Limited Polymyxin derivatives
HRP20220898T1 (hr) * 2013-05-22 2022-10-14 Spero Therapeutics, Inc. Derivati polimiksina i njihova upotreba u kombinacijskoj terapiji zajedno s različitim antibioticima
TWI709575B (zh) * 2014-03-11 2020-11-11 美商斯佩羅治療學股份有限公司 多黏菌素衍生物以及其與不同抗生素一起之組合療法的用途
PL3126376T3 (pl) 2014-04-01 2024-10-28 Monash University Pochodne polimyksyn jako związki przeciwdrobnoustrojowe
JP7349773B2 (ja) * 2014-11-26 2023-09-25 スペロ・セラピューティクス・インコーポレーテッド 化合物
WO2016100578A2 (en) 2014-12-16 2016-06-23 Micurx Pharmaceuticals, Inc. Antimicrobial polymyxins for treatment of bacterial infections
FI126143B (en) 2015-01-15 2016-07-15 Northern Antibiotics Oy Polymyxine derivative and its uses
US9763996B2 (en) 2015-01-16 2017-09-19 Northern Antibiotics, Ltd. Polymyxin derivative and uses thereof
US10322187B2 (en) 2015-08-10 2019-06-18 Lehigh University Reduced toxicity molecular conjugates of anti-fungal agents
AU2016331658B2 (en) * 2015-09-29 2021-04-01 Monash University Antimicrobial polymyxin derivative compounds
EP3512544B1 (en) * 2016-09-13 2020-10-28 Centauri Therapeutics Limited Peptide compounds and therapeutic uses thereof
CN108226315B (zh) * 2016-12-15 2022-04-12 上海医药工业研究院 一种检测多黏菌素e残留量的分析方法
WO2019084628A1 (en) * 2017-11-02 2019-05-09 The University Of Queensland Peptide antibiotics
UA128162C2 (uk) 2018-06-25 2024-04-24 Сперо Терапьютікс, Інк. Поліміксинові сполуки
CN111690040A (zh) * 2019-03-12 2020-09-22 上海来益生物药物研究开发中心有限责任公司 多粘菌素衍生物、其制备方法和应用
JP7045520B2 (ja) * 2020-01-02 2022-03-31 上海上薬第一生化薬業有限公司 ポリミキシンｂ成分又はその塩、その製造方法及び使用
CN115298198A (zh) 2020-01-21 2022-11-04 上海盟科药业股份有限公司 用于肾相关癌症靶向治疗的新型化合物和组合物
TW202233649A (zh) 2020-11-06 2022-09-01 美商斯佩羅治療學股份有限公司 化合物
CN112755174B (zh) * 2021-02-26 2022-11-18 沈阳药科大学 多粘菌素衍生物及其制备方法和应用
CN115490757B (zh) * 2021-06-18 2025-10-14 华南理工大学 活性氧自由基响应的多粘菌素前药化合物及其应用
NL2030897B1 (en) * 2022-02-11 2023-08-18 Univ Leiden Antibiotic compounds, formulations and methods of use

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2128617A (en) 1982-10-06 1984-05-02 Martti Vaara Polypeptides for use in antibacterial therapy
WO1988000950A2 (fr) 1986-08-06 1988-02-11 Fauchere Jean Luc Fabrication de conjugues a liaisons de covalence a partir d'un antibiotique et d'un derive non toxique de la polymyxine b
US20010021697A1 (en) 1987-09-14 2001-09-13 Henning Lowenstein Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom, proteinageous or polypeptide components thereof, or analogues of such proteinaceous or polypeptide components
TW274552B (OSRAM) 1992-05-26 1996-04-21 Hoechst Ag
US5767068A (en) 1997-02-13 1998-06-16 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
CN1886128A (zh) 2003-09-30 2006-12-27 柯西有限公司 用于治疗灼伤的组合物及方法
US20060004185A1 (en) 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
CN103059106B (zh) * 2006-08-11 2015-01-14 北方抗生素有限公司 多粘菌素衍生物及其用途
US8193148B2 (en) 2008-02-08 2012-06-05 Northern Antibiotics Ltd. Short fatty acid tail polymyxin derivatives and uses thereof
US8329645B2 (en) * 2008-02-08 2012-12-11 Northern Antibiotics Ltd. Polymyxin derivatives and uses thereof
FI20085469A0 (fi) * 2008-02-08 2008-05-16 Northern Antibiotics Oy Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä
ES2334547B1 (es) 2008-09-10 2010-12-03 Universidad De Barcelona Compuestos peptidicos antibacterianos.
TW201035111A (en) 2008-12-23 2010-10-01 Biosource Pharm Inc Antibiotic compositions for the treatment of gram negative infections
CN101851270A (zh) 2009-04-03 2010-10-06 梁浩 一种多粘菌素衍生物及其制备方法
WO2010130007A1 (en) 2009-05-14 2010-11-18 Monash University Antimicrobial compounds
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
WO2012051663A1 (en) 2010-10-21 2012-04-26 Monash University Antimicrobial compounds
WO2012168820A1 (en) * 2011-06-08 2012-12-13 Pfizer Inc. Polymyxin derivatives useful as antibacterial agents
CA2855916A1 (en) 2011-11-18 2013-05-23 Novacta Biosystems Limited Polymyxin derivatives
HRP20220898T1 (hr) 2013-05-22 2022-10-14 Spero Therapeutics, Inc. Derivati polimiksina i njihova upotreba u kombinacijskoj terapiji zajedno s različitim antibioticima
TWI709575B (zh) * 2014-03-11 2020-11-11 美商斯佩羅治療學股份有限公司 多黏菌素衍生物以及其與不同抗生素一起之組合療法的用途

Also Published As

Publication number Publication date
US20150031602A1 (en) 2015-01-29
WO2013072695A1 (en) 2013-05-23
EA024792B1 (ru) 2016-10-31
CA2855916A1 (en) 2013-05-23
CN103946233A (zh) 2014-07-23
EA201490634A1 (ru) 2014-12-30
SG11201402390PA (en) 2014-06-27
JP6185920B2 (ja) 2017-08-23
TWI608019B (zh) 2017-12-11
BR112014012016A2 (pt) 2017-05-16
US9234006B2 (en) 2016-01-12
JP2014533678A (ja) 2014-12-15
IL232278A0 (en) 2014-06-30
KR20140091724A (ko) 2014-07-22
TW201326215A (zh) 2013-07-01
AU2012338571A1 (en) 2014-05-22
MX355217B (es) 2018-04-10
EP2780357A1 (en) 2014-09-24
AU2012338571B2 (en) 2016-06-16
MX2014005542A (es) 2014-10-24

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