CO6382124A2 - Antagonistas del receptor ccr2 y usos de los mismos - Google Patents

Antagonistas del receptor ccr2 y usos de los mismos

Info

Publication number
CO6382124A2
CO6382124A2 CO11079269A CO11079269A CO6382124A2 CO 6382124 A2 CO6382124 A2 CO 6382124A2 CO 11079269 A CO11079269 A CO 11079269A CO 11079269 A CO11079269 A CO 11079269A CO 6382124 A2 CO6382124 A2 CO 6382124A2
Authority
CO
Colombia
Prior art keywords
ccr2
same
receiver antagonists
antagonists
receiver
Prior art date
Application number
CO11079269A
Other languages
English (en)
Inventor
Heiner Ebel
Sara Frattini
Riccardo Giovannini
Christoph Hoenke
Thomas Trieselmann
Patrick Tielmann
Stefan Scheuerer
Silke Marie Katrin Hobbie
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42049604&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6382124(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of CO6382124A2 publication Critical patent/CO6382124A2/es

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10—Spiro-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

La presente invención se refiere a antagonistas novedosos de formula (I), para el CCR2 (receptor 2 de quimioquina CC),y a su uso para proporcionar medicamentos para tratar afecciones y enfermedades, en especial enfermedades pulmonares tales como asma y EPOC.
CO11079269A 2008-12-19 2011-06-23 Antagonistas del receptor ccr2 y usos de los mismos CO6382124A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08172336 2008-12-19
EP09160416 2009-05-15

Publications (1)

Publication Number Publication Date
CO6382124A2 true CO6382124A2 (es) 2012-02-15

Family

ID=42049604

Family Applications (1)

Application Number Title Priority Date Filing Date
CO11079269A CO6382124A2 (es) 2008-12-19 2011-06-23 Antagonistas del receptor ccr2 y usos de los mismos

Country Status (28)

Country Link
US (3) US20120053164A1 (es)
EP (2) EP2816040B1 (es)
JP (2) JP2012512834A (es)
KR (1) KR101754698B1 (es)
CN (2) CN102256963B (es)
AR (1) AR074814A1 (es)
AU (1) AU2009327127C1 (es)
BR (1) BRPI0923051B1 (es)
CA (1) CA2747677C (es)
CL (1) CL2011001322A1 (es)
CO (1) CO6382124A2 (es)
DK (1) DK2379525T3 (es)
EA (1) EA020548B1 (es)
EC (1) ECSP11011163A (es)
ES (1) ES2551557T3 (es)
HK (1) HK1159099A1 (es)
HU (1) HUE025547T2 (es)
IL (1) IL212605A (es)
MA (1) MA33085B1 (es)
MX (1) MX2011005150A (es)
NZ (1) NZ592723A (es)
PE (1) PE20120061A1 (es)
PL (1) PL2379525T3 (es)
SG (1) SG172289A1 (es)
TN (1) TN2011000310A1 (es)
TW (1) TWI478913B (es)
WO (1) WO2010070032A1 (es)
ZA (1) ZA201103158B (es)

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JP2014141523A (ja) 2014-08-07
ECSP11011163A (es) 2011-07-29
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MA33085B1 (fr) 2012-03-01
US20120053164A1 (en) 2012-03-01
CN103724328A (zh) 2014-04-16
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US8835440B2 (en) 2014-09-16
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CN102256963A (zh) 2011-11-23

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