CO5140075A1 - Agentes terapeuticos para el tratamiento de la enfermedad de parkinson, adhd y microadenomas - Google Patents

Agentes terapeuticos para el tratamiento de la enfermedad de parkinson, adhd y microadenomas

Info

Publication number
CO5140075A1
CO5140075A1 CO99059863A CO99059863A CO5140075A1 CO 5140075 A1 CO5140075 A1 CO 5140075A1 CO 99059863 A CO99059863 A CO 99059863A CO 99059863 A CO99059863 A CO 99059863A CO 5140075 A1 CO5140075 A1 CO 5140075A1
Authority
CO
Colombia
Prior art keywords
microadenomas
adhd
parkinson
disease
treatment
Prior art date
Application number
CO99059863A
Other languages
English (en)
Inventor
Elisa Rose Jackson
Mclean Stafford
Howard Zorn Stevin
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of CO5140075A1 publication Critical patent/CO5140075A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Un compuesto de la fórmula<EMI FILE="99059863_1" ID="1" IMF=JPEG >o una sal de adición de ácidos farmacéuticamente aceptables del mismo, en la queX es N o CH;Y es<EMI FILE="99059863_2" ID="2" IMF=JPEG >SCH2, OCH2, Y1(CH2)n o Y1(CH2)n sustituido en el carbono con hasta 2 grupos metilo;n es 1 ó 2; eY1 es CH2, NH o NCH3;que es usado en el tratamiento de un trastorno seleccionado entre la enfermedad de Parkinson, ADHD y microadenomas en un mamífero.
CO99059863A 1998-09-21 1999-09-21 Agentes terapeuticos para el tratamiento de la enfermedad de parkinson, adhd y microadenomas CO5140075A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10119198P 1998-09-21 1998-09-21
US10386898P 1998-10-12 1998-10-12

Publications (1)

Publication Number Publication Date
CO5140075A1 true CO5140075A1 (es) 2002-03-22

Family

ID=26798000

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99059863A CO5140075A1 (es) 1998-09-21 1999-09-21 Agentes terapeuticos para el tratamiento de la enfermedad de parkinson, adhd y microadenomas

Country Status (38)

Country Link
US (2) US6300329B1 (es)
EP (1) EP1115402A1 (es)
JP (1) JP2002526448A (es)
KR (3) KR100468340B1 (es)
CN (1) CN1319013A (es)
AP (1) AP1456A (es)
AR (1) AR029739A1 (es)
AU (1) AU760230B2 (es)
BG (1) BG105445A (es)
BR (1) BR9913975A (es)
CA (1) CA2344670A1 (es)
CO (1) CO5140075A1 (es)
CZ (1) CZ20011006A3 (es)
DZ (1) DZ2894A1 (es)
EA (2) EA200100204A1 (es)
EE (1) EE200100179A (es)
GE (1) GEP20033081B (es)
GT (1) GT199900154A (es)
HN (1) HN1999000146A (es)
HR (1) HRP20010209A2 (es)
HU (1) HUP0103691A3 (es)
ID (1) ID28028A (es)
IL (2) IL164839A0 (es)
IS (1) IS5852A (es)
MA (1) MA26690A1 (es)
MY (1) MY127939A (es)
NO (1) NO20011409L (es)
NZ (1) NZ509855A (es)
OA (1) OA11653A (es)
PA (1) PA8482001A1 (es)
PE (1) PE20001084A1 (es)
PL (1) PL346904A1 (es)
SK (1) SK3592001A3 (es)
TN (1) TNSN99177A1 (es)
TR (2) TR200101357T2 (es)
TW (1) TW518225B (es)
WO (1) WO2000016777A1 (es)
YU (1) YU21701A (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1999000146A (es) * 1998-09-21 2000-11-11 Pfizer Prod Inc Agentes farmaceuticos para el tratamiento de la enfermedad de parkinson, adhd y microadenomas.
EP1274444B1 (en) * 2000-03-16 2013-05-15 THE McLEAN HOSPITAL CORPORATION Cdp-choline and uridine for the treatment of alcohol abuse
GB0027020D0 (en) * 2000-11-03 2000-12-20 Univ Manchester Treatment of movement disorders
US7053092B2 (en) 2001-01-29 2006-05-30 Otsuka Pharmaceutical Co., Ltd. 5-HT1a receptor subtype agonist
AU2002315336A1 (en) 2001-06-18 2003-01-02 Psychiatric Genomics, Inc. Method for neural stem cell differentiation using 5ht-1a agonists
US20030036555A1 (en) * 2001-08-03 2003-02-20 Boehringer Ingelheim Pharma Kg Pramipexole for the treatment of ADHD
AR033485A1 (es) 2001-09-25 2003-12-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
US7737128B2 (en) * 2004-06-10 2010-06-15 The Mclean Hospital Corporation Pyrimidines, such as uridine, in treatments for patients with bipolar disorder
US7947661B2 (en) * 2004-08-11 2011-05-24 The Mclean Hospital Corporation Compounds for the treatment of marihuana dependence, withdrawal, and usage
MY148644A (en) 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
GT200600414A (es) 2005-09-12 2007-09-20 Sal de glucuranato de compuesto de piperazine
GT200600416A (es) 2005-09-12 2007-09-20 Sales salicilato y gentisato de un compuesto de piperazina
TW200800306A (en) 2005-09-12 2008-01-01 Wyeth Corp Sustained-release formulation and uses thereof
US9066903B2 (en) * 2006-02-28 2015-06-30 The United States Of America As Represented By The Department Of Veterans Affairs Pharmacological treatment of Parkinson's disease
US20080131492A1 (en) * 2006-06-23 2008-06-05 Spherics, Inc. Dosage forms for movement disorder treatment
WO2008083442A1 (en) * 2007-01-10 2008-07-17 Brc Operations Pty Limited Method for formulating combination medications for adhd
CN101318020B (zh) * 2007-06-06 2011-09-28 四川科瑞德制药有限公司 抗焦虑或/和抗抑郁的药物组合物及用途
US20100041621A1 (en) * 2008-08-15 2010-02-18 Perry Renshaw Methods and compositions for improving cognitive performance
GB201112987D0 (en) 2011-07-28 2011-09-14 Ge Healthcare Ltd Novel compound
WO2014078568A1 (en) 2012-11-14 2014-05-22 The Johns Hopkins University Methods and compositions for treating schizophrenia
US9463186B2 (en) 2013-04-15 2016-10-11 Northwestern University Treatment for dopaminergic disorders
CN104892589A (zh) 2014-03-07 2015-09-09 中国科学院上海药物研究所 一类杂环化合物、其制备方法和用途
WO2016186968A1 (en) 2015-05-15 2016-11-24 The Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for treating motor disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX19222A (es) * 1989-01-23 1993-12-01 Pfizer Agentes ansioliticos bis-aza-biciclicos
WO1992000075A1 (en) * 1990-06-29 1992-01-09 Pfizer Inc. Pyridopyrazine derivatives for treating substance abuse and addiction
US5281607B1 (en) * 1992-10-08 1998-05-19 Univ New York Method of using alpha 2-antagonists for the treatment of neurodegenerative diseases
GB9408084D0 (en) * 1994-04-23 1994-06-15 Boots Co Plc Medical treatment
PT765320E (pt) * 1994-06-14 2002-02-28 Pfizer Derivados da benzimidazolona com actividade dopaminergica central
US5877183A (en) * 1996-06-06 1999-03-02 Ergo Research Corporation Treatment of lipid and glucose metabolism disorders with dopamine and serotonin agonists
HN1999000146A (es) * 1998-09-21 2000-11-11 Pfizer Prod Inc Agentes farmaceuticos para el tratamiento de la enfermedad de parkinson, adhd y microadenomas.

Also Published As

Publication number Publication date
TR200402083T2 (tr) 2004-10-21
CN1319013A (zh) 2001-10-24
IL141507A0 (en) 2002-03-10
AR029739A1 (es) 2003-07-16
CZ20011006A3 (cs) 2001-09-12
JP2002526448A (ja) 2002-08-20
PE20001084A1 (es) 2000-10-18
MA26690A1 (fr) 2004-12-20
GT199900154A (es) 2001-03-06
US6608064B2 (en) 2003-08-19
KR100468340B1 (ko) 2005-01-27
DZ2894A1 (fr) 2003-12-15
TNSN99177A1 (fr) 2005-11-10
TW518225B (en) 2003-01-21
MY127939A (en) 2007-01-31
AP1456A (en) 2005-09-30
OA11653A (en) 2004-12-08
AU760230B2 (en) 2003-05-08
PL346904A1 (en) 2002-03-11
EA200301063A1 (ru) 2004-12-30
KR20040054752A (ko) 2004-06-25
TR200101357T2 (tr) 2001-08-21
BG105445A (en) 2001-12-29
AU5383199A (en) 2000-04-10
KR20010075222A (ko) 2001-08-09
AP2001002102A0 (en) 2001-03-31
BR9913975A (pt) 2001-06-19
YU21701A (sh) 2004-07-15
HN1999000146A (es) 2000-11-11
PA8482001A1 (es) 2000-05-24
HUP0103691A2 (hu) 2002-02-28
EP1115402A1 (en) 2001-07-18
EE200100179A (et) 2002-10-15
ID28028A (id) 2001-05-03
IS5852A (is) 2001-02-20
CA2344670A1 (en) 2000-03-30
IL164839A0 (en) 2005-12-18
KR20030088512A (ko) 2003-11-19
US20010034347A1 (en) 2001-10-25
NO20011409L (no) 2001-03-28
US6300329B1 (en) 2001-10-09
EA200100204A1 (ru) 2001-08-27
HUP0103691A3 (en) 2003-01-28
WO2000016777A1 (en) 2000-03-30
HRP20010209A2 (en) 2002-04-30
GEP20033081B (en) 2003-10-27
NZ509855A (en) 2003-04-29
NO20011409D0 (no) 2001-03-20
SK3592001A3 (en) 2001-12-03

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