NO976043D0 - Terapautiske forbindelser - Google Patents

Terapautiske forbindelser

Info

Publication number
NO976043D0
NO976043D0 NO976043A NO976043A NO976043D0 NO 976043 D0 NO976043 D0 NO 976043D0 NO 976043 A NO976043 A NO 976043A NO 976043 A NO976043 A NO 976043A NO 976043 D0 NO976043 D0 NO 976043D0
Authority
NO
Norway
Prior art keywords
hydrogen
compounds
oac
therapeutic compounds
nhac
Prior art date
Application number
NO976043A
Other languages
English (en)
Other versions
NO976043L (no
Inventor
Stephen Martin Courtney
Original Assignee
Oxford Glycosciences Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9512868.2A external-priority patent/GB9512868D0/en
Priority claimed from GBGB9608372.0A external-priority patent/GB9608372D0/en
Priority claimed from GBGB9608547.7A external-priority patent/GB9608547D0/en
Application filed by Oxford Glycosciences Uk Ltd filed Critical Oxford Glycosciences Uk Ltd
Publication of NO976043D0 publication Critical patent/NO976043D0/no
Publication of NO976043L publication Critical patent/NO976043L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/073Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
NO976043A 1995-06-23 1997-12-22 Terapeutiske forbindelser NO976043L (no)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GBGB9512868.2A GB9512868D0 (en) 1995-06-23 1995-06-23 Therapeutic compounds
GBGB9608372.0A GB9608372D0 (en) 1996-04-23 1996-04-23 Therapeutic compounds
GBGB9608547.7A GB9608547D0 (en) 1996-04-25 1996-04-25 Therapeutic compounds
US1676296P 1996-05-03 1996-05-03
US1697396P 1996-05-07 1996-05-07
PCT/GB1996/001519 WO1997000882A1 (en) 1995-06-23 1996-06-24 Therapeutic compounds

Publications (2)

Publication Number Publication Date
NO976043D0 true NO976043D0 (no) 1997-12-22
NO976043L NO976043L (no) 1998-02-20

Family

ID=27517294

Family Applications (1)

Application Number Title Priority Date Filing Date
NO976043A NO976043L (no) 1995-06-23 1997-12-22 Terapeutiske forbindelser

Country Status (16)

Country Link
US (1) US5945406A (no)
EP (1) EP0851866B1 (no)
JP (1) JPH11507942A (no)
KR (1) KR19990028344A (no)
CN (1) CN1196059A (no)
AT (1) ATE204878T1 (no)
AU (1) AU6234296A (no)
CA (1) CA2225247A1 (no)
DE (1) DE69614867T2 (no)
ES (1) ES2162078T3 (no)
HU (1) HUP9901438A3 (no)
ID (1) ID16479A (no)
IL (1) IL122700A0 (no)
NO (1) NO976043L (no)
PL (1) PL328266A1 (no)
WO (1) WO1997000882A1 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11507942A (ja) * 1995-06-23 1999-07-13 オックスフォード グリコサイエンセス(ユーケー) リミテッド 治療用化合物
DE19741738A1 (de) * 1997-09-22 1999-03-25 Hoechst Ag Linker-Nucleosid, seine Herstellung und Verwendung
DE19741715A1 (de) 1997-09-22 1999-03-25 Hoechst Ag Pentopyranosyl-Nucleosid, seine Herstellung und Verwendung
DE19837387A1 (de) 1998-08-18 2000-02-24 Aventis Res & Tech Gmbh & Co 3'-Desoxypentopyranosyl-Nucleinsäure, ihre Herstellung und Verwendung
US6344460B1 (en) * 1999-03-19 2002-02-05 Lonza Inc. Propynyl uracils
US20050143300A1 (en) * 2003-10-10 2005-06-30 Ma Jian-Xing Compounds useful in inhibiting vascular leakage, inflammation and fibrosis and methods of making and using same
CN102149388B (zh) * 2008-07-11 2014-11-05 得克萨斯系统大学评议会 具有抗癌活性的新型2-脱氧单糖乙酸酯
US10201554B2 (en) 2013-04-05 2019-02-12 Board Of Regents, The University Of Texas System Esters of 2-deoxy-monosacharides with anti proliferative activity

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3354160A (en) * 1965-07-22 1967-11-21 Hoffmann La Roche Tri-lower alkyl-silyl-5-fluoropyrimidines
DK149818C (da) * 1976-10-28 1987-04-06 Sankyo Co Analogifremgangsmaade til fremstilling af 5-fluoruracil-derivater
US4248999A (en) * 1976-10-28 1981-02-03 Sankyo Company Limited 5-Fluorouracil derivatives and process for preparing thereof
JPS55153796A (en) * 1979-05-21 1980-11-29 Meiji Seika Kaisha Ltd 5-fluorouracil nucleoside and its preparation
JPS5829798A (ja) * 1981-08-15 1983-02-22 Tetsuo Suami ヌクレオシド類似体
JPS5872599A (ja) * 1981-10-27 1983-04-30 Kanto Ishi Pharma Co Ltd 複合糖質誘導体
EP0119650A3 (en) * 1983-03-21 1987-09-30 THE PROCTER & GAMBLE COMPANY Galactosyl-insulin conjugates useful in treating diabetics
JP2696393B2 (ja) * 1989-05-09 1998-01-14 株式会社日本抗体研究所 チミン誘導体及びこれを含有する抗hiv剤
JPH0517494A (ja) * 1991-07-10 1993-01-26 Nippon Shoji Kk グルコサミン誘導体
JPH10507763A (ja) * 1994-10-24 1998-07-28 ジェネンコア インターナショナル インコーポレーテッド L−ピラノシルヌクレオシド
JPH11507942A (ja) * 1995-06-23 1999-07-13 オックスフォード グリコサイエンセス(ユーケー) リミテッド 治療用化合物
GB9626450D0 (en) * 1996-12-20 1997-02-05 Oxford Glycosciences Uk Ltd Therapeutic compounds

Also Published As

Publication number Publication date
ID16479A (id) 1997-10-02
US5945406A (en) 1999-08-31
EP0851866A1 (en) 1998-07-08
IL122700A0 (en) 1998-12-06
WO1997000882A1 (en) 1997-01-09
KR19990028344A (ko) 1999-04-15
MX9710529A (es) 1998-08-30
AU6234296A (en) 1997-01-22
HUP9901438A2 (hu) 1999-08-30
DE69614867D1 (de) 2001-10-04
HUP9901438A3 (en) 2000-07-28
DE69614867T2 (de) 2002-04-11
EP0851866B1 (en) 2001-08-29
ATE204878T1 (de) 2001-09-15
NO976043L (no) 1998-02-20
JPH11507942A (ja) 1999-07-13
CA2225247A1 (en) 1997-01-09
CN1196059A (zh) 1998-10-14
ES2162078T3 (es) 2001-12-16
PL328266A1 (en) 1999-01-18

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