CO2019013020A2 - Anticuerpo anti-cdh6 y conjugado farmaco-anticuerpo anticdh6 - Google Patents

Anticuerpo anti-cdh6 y conjugado farmaco-anticuerpo anticdh6

Info

Publication number
CO2019013020A2
CO2019013020A2 CONC2019/0013020A CO2019013020A CO2019013020A2 CO 2019013020 A2 CO2019013020 A2 CO 2019013020A2 CO 2019013020 A CO2019013020 A CO 2019013020A CO 2019013020 A2 CO2019013020 A2 CO 2019013020A2
Authority
CO
Colombia
Prior art keywords
antibody
drug conjugate
cdh6
drug
tumor
Prior art date
Application number
CONC2019/0013020A
Other languages
English (en)
Inventor
Atsuko Saito
Tsuyoshi Hirata
Kensuke Nakamura
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=64273811&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO2019013020(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of CO2019013020A2 publication Critical patent/CO2019013020A2/es

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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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Abstract

Un objeto de la presente invención es suministrar un anticuerpo que se une a CDH6 y que tiene actividad de internalización, un conjugado anticuerpo-fármaco del anticuerpo y un fármaco que tiene actividad antitumoral, un producto farmacéutico que comprende el conjugado anticuerpo-fármaco y que tiene efectos terapéuticos sobre un tumor, un método para tratar un tumor usando el anticuerpo, el conjugado anticuerpo-fármaco o el producto farmacéutico, y similares. La presente invención suministra un anticuerpo anti-CDH6 que tiene actividad de internalización, un conjugado anticuerpo-fármaco del anticuerpo y un fármaco que tiene actividad antitumoral, un producto farmacéutico que comprende el anticuerpo o el conjugado anticuerpo-fármaco, y un método para tratar un tumor.
CONC2019/0013020A 2017-05-15 2019-11-21 Anticuerpo anti-cdh6 y conjugado farmaco-anticuerpo anticdh6 CO2019013020A2 (es)

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