BR112018001292A2 - métodos para melhor liberação de agentes ativos a tumores - Google Patents
métodos para melhor liberação de agentes ativos a tumoresInfo
- Publication number
- BR112018001292A2 BR112018001292A2 BR112018001292A BR112018001292A BR112018001292A2 BR 112018001292 A2 BR112018001292 A2 BR 112018001292A2 BR 112018001292 A BR112018001292 A BR 112018001292A BR 112018001292 A BR112018001292 A BR 112018001292A BR 112018001292 A2 BR112018001292 A2 BR 112018001292A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- tumors
- active agents
- better release
- agents
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 239000012867 bioactive agent Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 210000002615 epidermis Anatomy 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
a presente invenção diz respeito à entrega de agentes através da pele. os métodos para fornecer agentes, tais como agentes bioativos, são contemplados pela presente invenção. especificamente, métodos para a entrega direcionada de agentes para uma ou mais áreas da epiderme e, assim, para um ou mais tumores de câncer são descritos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562196570P | 2015-07-24 | 2015-07-24 | |
US201562196578P | 2015-07-24 | 2015-07-24 | |
PCT/US2016/043623 WO2017019526A2 (en) | 2015-07-24 | 2016-07-22 | Methods for better delivery of active agents to tumors |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112018001292A2 true BR112018001292A2 (pt) | 2018-09-11 |
Family
ID=57885141
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018001292A BR112018001292A2 (pt) | 2015-07-24 | 2016-07-22 | métodos para melhor liberação de agentes ativos a tumores |
Country Status (15)
Country | Link |
---|---|
US (3) | US10806913B2 (pt) |
EP (2) | EP3925599A1 (pt) |
JP (1) | JP7082041B2 (pt) |
KR (1) | KR20180035209A (pt) |
CN (1) | CN107921248A (pt) |
AU (3) | AU2016297823B2 (pt) |
BR (1) | BR112018001292A2 (pt) |
CA (1) | CA2991455C (pt) |
DK (1) | DK3325080T3 (pt) |
ES (1) | ES2891523T3 (pt) |
HU (1) | HUE056410T2 (pt) |
MX (2) | MX2018000166A (pt) |
PL (1) | PL3325080T3 (pt) |
RU (1) | RU2719943C2 (pt) |
WO (1) | WO2017019526A2 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107921248A (zh) * | 2015-07-24 | 2018-04-17 | 金伯利-克拉克环球有限公司 | 用于向肿瘤更佳地递送活性剂的方法 |
KR20180035210A (ko) * | 2015-07-24 | 2018-04-05 | 킴벌리-클라크 월드와이드, 인크. | 활성제의 류마티즘 전달 방법 |
US11541015B2 (en) | 2017-05-17 | 2023-01-03 | Massachusetts Institute Of Technology | Self-righting systems, methods, and related components |
EP3624887A4 (en) | 2017-05-17 | 2021-02-24 | Massachusetts Institute of Technology | TISSUE ANCHORING ARTICLES |
EP3652133A4 (en) | 2017-07-10 | 2021-04-21 | Basf Se | MIXTURES INCLUDING A UREASE INHIBITOR (IU) AND A NITRIFICATION INHIBITOR SUCH AS 2- (3,4-DIMETHYL-1H-PYRAZOL-1-YL) SUCCINIC ACID (DMPSA) OR 3,4-DIMETHYL PYRAZOLIUM GLYCOLATE (DMPG) |
WO2019222570A1 (en) | 2018-05-17 | 2019-11-21 | Massachusetts Institute Of Technology | Systems for electrical stimulation |
AU2019277577A1 (en) * | 2018-05-31 | 2020-12-24 | Vivasor, Inc. | Drug delivery methods targeting the lymphatic system |
US20210308440A1 (en) * | 2018-09-24 | 2021-10-07 | L'oreal | Device comprising microneedles for skin-coloring |
US20230001170A1 (en) | 2019-12-05 | 2023-01-05 | Sorrento Therapeutics, Inc. | Method of treating cancer by administration of an anti-pd-1 or anti-pd-l1 therapeutic agent via a lymphatic devliery device |
EP4281167A1 (en) | 2021-01-22 | 2023-11-29 | Sorrento Therapeutics, Inc. | Device for microliter-scale lymphatic delivery of coronavirus vaccines |
WO2022192594A2 (en) | 2021-03-11 | 2022-09-15 | Sorrento Therapeutics, Inc. | Nucleic acid molecules and vaccines comprising same for the prevention and treatment of coronavirus infections and disease |
AU2022290563A1 (en) | 2021-06-09 | 2024-01-25 | Vivasor, Inc. | Method of treating cancer by administration of an anti-pd-1 or anti-pd-l1 therapeutic agent via a lymphatic microneedle delivery device |
WO2023023074A1 (en) | 2021-08-18 | 2023-02-23 | Sorrento Therapeutics, Inc. | Therapeutic agents targeting the lymphatic system |
Family Cites Families (30)
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IE72524B1 (en) | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
AU785199B2 (en) | 2000-06-01 | 2006-11-02 | Watson Pharmaceuticals, Inc. | Transdermal delivery of lasofoxifene |
JP4383168B2 (ja) * | 2001-09-12 | 2009-12-16 | ベクトン・ディキンソン・アンド・カンパニー | マイクロ針投与デバイスおよび薬物投与デバイス |
JP2007500251A (ja) * | 2003-06-13 | 2007-01-11 | ベクトン・ディキンソン・アンド・カンパニー | 生物学的に活性な作用物質の改良型皮内送達 |
WO2005023328A2 (en) | 2003-08-26 | 2005-03-17 | Becton Dickinson And Company | Methods for intradermal delivery of therapeutics agents |
AU2005284908B2 (en) | 2004-09-13 | 2011-12-08 | Morningside Venture Investments Limited | Biosynchronous transdermal drug delivery |
US20070088414A1 (en) * | 2005-05-25 | 2007-04-19 | Campbell Robert L | Particulate formulations for intradermal delivery of biologically active agents |
WO2006138719A2 (en) * | 2005-06-17 | 2006-12-28 | Georgia Tech Research Corporation | Coated microstructures and method of manufacture thereof |
US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
EP2100850A1 (en) * | 2008-03-11 | 2009-09-16 | Stichting Voor De Technische Wetenschappen | Microneedle array and a method for manufacturing microneedles |
US8715736B2 (en) | 2009-04-30 | 2014-05-06 | Florida Agricultural And Mechanical University | Nanoparticle formulations for skin delivery |
CN101829394B (zh) * | 2010-04-27 | 2012-08-22 | 上海交通大学 | 台阶微针阵列的制备方法 |
CA2797202A1 (en) | 2010-04-28 | 2012-02-16 | Kimberly-Clark Worldwide, Inc. | Injection molded microneedle array and method for forming the microneedle array |
JP5860033B2 (ja) | 2010-04-28 | 2016-02-16 | キンバリー クラーク ワールドワイド インコーポレイテッド | siRNA送達用の医療デバイス |
US9586044B2 (en) | 2010-04-28 | 2017-03-07 | Kimberly-Clark Worldwide, Inc. | Method for increasing the permeability of an epithelial barrier |
JP5860032B2 (ja) | 2010-04-28 | 2016-02-16 | キンバリー クラーク ワールドワイド インコーポレイテッド | 関節リウマチ薬の送達のためのデバイス |
US20120187814A1 (en) | 2011-01-25 | 2012-07-26 | Fryling Nicholas A | Furniture System and a Frame Assembly for a Furniture System |
US20120245445A1 (en) * | 2011-03-21 | 2012-09-27 | Michael Darryl Black | Glucose Monitoring System |
AU2012326203B2 (en) | 2011-10-17 | 2017-11-30 | Massachusetts Institute Of Technology | Intracellular delivery |
KR102388880B1 (ko) * | 2011-10-27 | 2022-04-22 | 소렌토 쎄라퓨틱스, 인코포레이티드 | 고점도 생체활성 제제의 경피 전달 방법 |
KR101575039B1 (ko) * | 2012-07-19 | 2015-12-07 | (주)아모레퍼시픽 | 노즐 장치 및 이를 포함하는 최소 침습형 주입 장치 |
CN110025881A (zh) * | 2012-09-13 | 2019-07-19 | 亚夫拉罕·阿米尔 | 用于皮肤改善的递送装置和方法 |
AU2013318338B2 (en) | 2012-09-21 | 2017-05-25 | Intensity Therapeutics, Inc | Method of treating cancer |
CN103157178B (zh) * | 2013-02-05 | 2014-12-31 | 北京化工大学 | 精确控制微针插入长度的印章式工具 |
US9861801B2 (en) | 2013-02-28 | 2018-01-09 | Kimberly-Clark Worldwide, Inc. | Drug delivery device |
US10183156B2 (en) | 2013-02-28 | 2019-01-22 | Sorrento Therapeutics, Inc. | Transdermal drug delivery device |
BR112015027608A2 (pt) | 2013-05-23 | 2017-07-25 | Kimberly Clark Co | microagulhas com geometrias transversais de canal aberto melhoradas |
US10376674B2 (en) * | 2014-09-15 | 2019-08-13 | Ethicon, Inc. | System and method for targeted delivery of therapeutic agents to tissue |
KR20180035210A (ko) * | 2015-07-24 | 2018-04-05 | 킴벌리-클라크 월드와이드, 인크. | 활성제의 류마티즘 전달 방법 |
CN107921248A (zh) * | 2015-07-24 | 2018-04-17 | 金伯利-克拉克环球有限公司 | 用于向肿瘤更佳地递送活性剂的方法 |
-
2016
- 2016-07-22 CN CN201680042970.5A patent/CN107921248A/zh active Pending
- 2016-07-22 PL PL16831139T patent/PL3325080T3/pl unknown
- 2016-07-22 JP JP2018500406A patent/JP7082041B2/ja active Active
- 2016-07-22 US US15/744,346 patent/US10806913B2/en active Active
- 2016-07-22 DK DK16831139.7T patent/DK3325080T3/da active
- 2016-07-22 ES ES16831139T patent/ES2891523T3/es active Active
- 2016-07-22 WO PCT/US2016/043623 patent/WO2017019526A2/en active Application Filing
- 2016-07-22 HU HUE16831139A patent/HUE056410T2/hu unknown
- 2016-07-22 EP EP21189656.8A patent/EP3925599A1/en active Pending
- 2016-07-22 MX MX2018000166A patent/MX2018000166A/es unknown
- 2016-07-22 CA CA2991455A patent/CA2991455C/en active Active
- 2016-07-22 KR KR1020187003326A patent/KR20180035209A/ko active IP Right Grant
- 2016-07-22 RU RU2018104102A patent/RU2719943C2/ru active
- 2016-07-22 AU AU2016297823A patent/AU2016297823B2/en active Active
- 2016-07-22 EP EP16831139.7A patent/EP3325080B1/en active Active
- 2016-07-22 BR BR112018001292A patent/BR112018001292A2/pt not_active Application Discontinuation
-
2018
- 2018-01-08 MX MX2022014277A patent/MX2022014277A/es unknown
-
2020
- 2020-09-16 US US17/022,855 patent/US20210052871A1/en not_active Abandoned
-
2021
- 2021-01-12 AU AU2021200146A patent/AU2021200146B2/en active Active
-
2022
- 2022-11-21 AU AU2022275397A patent/AU2022275397A1/en active Pending
-
2024
- 2024-03-29 US US18/622,067 patent/US20240238570A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2016297823B2 (en) | 2020-10-22 |
RU2719943C2 (ru) | 2020-04-23 |
MX2022014277A (es) | 2022-12-07 |
US20180193624A1 (en) | 2018-07-12 |
US20240238570A1 (en) | 2024-07-18 |
JP7082041B2 (ja) | 2022-06-07 |
EP3325080A2 (en) | 2018-05-30 |
WO2017019526A2 (en) | 2017-02-02 |
EP3325080B1 (en) | 2021-09-01 |
AU2022275397A1 (en) | 2023-01-05 |
RU2018104102A3 (pt) | 2019-11-06 |
CN107921248A (zh) | 2018-04-17 |
EP3925599A1 (en) | 2021-12-22 |
JP2018521755A (ja) | 2018-08-09 |
US10806913B2 (en) | 2020-10-20 |
CA2991455C (en) | 2023-10-10 |
ES2891523T3 (es) | 2022-01-28 |
AU2021200146A1 (en) | 2021-03-18 |
EP3325080A4 (en) | 2019-04-17 |
AU2021200146B2 (en) | 2022-08-25 |
KR20180035209A (ko) | 2018-04-05 |
AU2016297823A1 (en) | 2018-02-15 |
CA2991455A1 (en) | 2017-02-02 |
US20210052871A1 (en) | 2021-02-25 |
PL3325080T3 (pl) | 2022-01-24 |
RU2018104102A (ru) | 2019-08-27 |
DK3325080T3 (da) | 2021-10-04 |
HUE056410T2 (hu) | 2022-02-28 |
MX2018000166A (es) | 2018-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: SORRENTO THERAPEUTICS, INC. (US) |
|
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |