CO2017004898A2 - Inhibidores del bromodominio derivados de 6h-tieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepina - Google Patents

Inhibidores del bromodominio derivados de 6h-tieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepina

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Publication number
CO2017004898A2
CO2017004898A2 CONC2017/0004898A CO2017004898A CO2017004898A2 CO 2017004898 A2 CO2017004898 A2 CO 2017004898A2 CO 2017004898 A CO2017004898 A CO 2017004898A CO 2017004898 A2 CO2017004898 A2 CO 2017004898A2
Authority
CO
Colombia
Prior art keywords
diazepine
thieno
triazolo
bromodomain inhibitors
inhibitors derived
Prior art date
Application number
CONC2017/0004898A
Other languages
English (en)
Spanish (es)
Inventor
B Steven Landau
Michael Kagey
Original Assignee
Tensha Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tensha Therapeutics Inc filed Critical Tensha Therapeutics Inc
Publication of CO2017004898A2 publication Critical patent/CO2017004898A2/es

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
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    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/04—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 condensed with carbocyclic rings or ring systems
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    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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CONC2017/0004898A 2014-10-27 2017-05-16 Inhibidores del bromodominio derivados de 6h-tieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepina CO2017004898A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462068983P 2014-10-27 2014-10-27
PCT/US2015/057538 WO2016069578A1 (en) 2014-10-27 2015-10-27 Bromodomain inhibitors

Publications (1)

Publication Number Publication Date
CO2017004898A2 true CO2017004898A2 (es) 2017-10-31

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Application Number Title Priority Date Filing Date
CONC2017/0004898A CO2017004898A2 (es) 2014-10-27 2017-05-16 Inhibidores del bromodominio derivados de 6h-tieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepina

Country Status (19)

Country Link
US (1) US10124009B2 (enExample)
EP (1) EP3212654B1 (enExample)
JP (1) JP6715243B2 (enExample)
KR (1) KR20170068597A (enExample)
CN (1) CN107635979A (enExample)
AU (1) AU2015339511B2 (enExample)
BR (1) BR112017008714A2 (enExample)
CA (1) CA2965330A1 (enExample)
CL (1) CL2017001046A1 (enExample)
CO (1) CO2017004898A2 (enExample)
CR (1) CR20170219A (enExample)
EA (1) EA033325B1 (enExample)
IL (1) IL251784A0 (enExample)
MX (1) MX376748B (enExample)
PE (1) PE20171042A1 (enExample)
PH (1) PH12017500745A1 (enExample)
SG (1) SG11201703414VA (enExample)
UA (1) UA122130C2 (enExample)
WO (1) WO2016069578A1 (enExample)

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