CN2347982Y - Simple fermentor for producing microbiological products - Google Patents

Simple fermentor for producing microbiological products Download PDF

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Publication number
CN2347982Y
CN2347982Y CN 98227774 CN98227774U CN2347982Y CN 2347982 Y CN2347982 Y CN 2347982Y CN 98227774 CN98227774 CN 98227774 CN 98227774 U CN98227774 U CN 98227774U CN 2347982 Y CN2347982 Y CN 2347982Y
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China
Prior art keywords
transparent
transparent soft
soft bag
closed tube
pipe clamp
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Expired - Fee Related
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CN 98227774
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Chinese (zh)
Inventor
余兆丰
余兰
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Individual
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Individual
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Priority to CN 98227774 priority Critical patent/CN2347982Y/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/14Bags
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/22Transparent or translucent parts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/26Constructional details, e.g. recesses, hinges flexible
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/58Reaction vessels connected in series or in parallel

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The utility model relates to a simple fermenting device used for producing microbiological products, which is combined by a plurality of fermenting containers and communicating pipes connected with the fermenting containers. The fermenting containers are transparent soft bags; the communicating pipes are transparent soft pipes; the connecting points between the transparent soft bags and the transparent soft pipes are in a direct connecting communication combining state; each transparent soft bag can be connected and communicated with one to a plurality of transparent soft pipes; a pipeline system formed has the three functions of conveying culture solution, venting and mixing, and regulating the gas pressure in the fermenting containers, and the functions are essential to the device. The utility model has the advantages of small size, simple structure, and flexible operation.

Description

The simple and easy fermentation unit of microbial product production
The utility model relates to a kind of fermentation unit of producing microbial product.
The deep liquid fermentation process technology has been widely used in fungi, antibiotic, monosodium glutamate, citric acid and some production of enzyme preparation, but because technology difficulty is big, the equipment complexity is huge, auxiliary facility is required high reason, not only restricting the reduction of industrial production cost and the expansion of scale, popularize in numerous middle and small scale production and operation but also influence it, document CN86102421 and CN89219267 have successively disclosed a kind of microbial product submerged fermentation production equipment that is made of glass and the metal fermentation unit multistage closed conduit system by the mutual UNICOM of aseptic technique respectively, since container and with the pipeline of its rigid connection and fixing heavy auxiliary facility, make the whole production equipment volume still very big, operate extremely not conveniently, cost is also very high, so can only be applicable to certain production-scale production.
It is little that task of the present utility model provides a kind of volume, easy to operate, and cost is low, and industrial scale microbial product applied widely produces uses simple and easy fermentation unit.
The simple and easy fermentation unit of microbial product production that technical solutions of the utility model are related, be to connect with the closed tube that is connected with it by a plurality of fermenting containers to combine, wherein said fermenting container is transparent soft bag, described closed tube is a transparent hose, be the combining form that direct connection connects between transparent soft bag and the transparent hose in the junction, thereby make this device become a multipole airtight bactogen with flexible integral structure feature.In this device, have one on every transparent soft bag to the directly connection perforation with it of several transparent hoses, the tubing system of formation has this and installs prerequisite aeration-agitation, nutrient solution conveying and regulate three kinds of functions of soft bag internal gas pressure.
Advantage of the present utility model is, directly connect the airtight bactogen of flexible integrated multistage that connects and constitute by transparent soft bag and flexible pipe, make its one-piece construction volume become littler, simpler, operate also more flexiblely, also can simplify tubing system structure and auxiliary facility, can be made into the disposable plastic product, reduce production costs, thereby be not only applicable to the suitability for industrialized production of extensive microbial product, also applicable to such as individuality, family small-scale production.
Embodiment of the present utility model is described below by the tubing system structure iron of three grades of airtight continuous apparatus.
Fig. 1 directly connects the culture apparatus tubing system structure iron that connects three transparent hoses on a transparent soft bag;
Fig. 2 directly connects the culture apparatus tubing system structure iron that connects two transparent hoses on a transparent soft bag:
Fig. 3 directly connects the culture apparatus tubing system structure iron that connects a transparent hose on a transparent soft bag;
Device shown in Figure 1 has closed tube 3, closed tube 4 and 5 three transparent hoses of closed tube and should connect connection by transparent soft bag 1 on a transparent soft bag 1 that is used for splendid attire nutrient solution 2, wherein: closed tube 3 one ends stretch into nutrient solution 2 liquid levels top in the transparent soft bag 1, and the other end is added with air filter 7 and pipe clamp 13; Closed tube 4 one ends put in the depths of nutrient solution 2, and the other end communicates with air pump 14 through air filter 8 and air filter 9, is added with pipe clamp 12 between two air filters 8,9 in pipeline; One end of closed tube 5 stretches into nutrient solution 2 depths, and the other end connects in transparent soft bag 1 mutual intersections at different levels, and the stopple coupon 6 and the shunt pipe clamp 10 of band pipe clamp 11 is housed on pipe 5 paths.
Device shown in Figure 2, on each only is used for the transparent soft bag 1 of splendid attire nutrient solution 2, closed tube 15 and 16 two transparent hoses of closed tube and its perforation connection are arranged, wherein air filter 18 is equipped with in closed tube 15 upper ends, nutrient solution 2 liquid levels top in the transparent soft bag 1 is stretched in the lower end, closed tube 16 has an end to stretch into liquid level 2 depths in the transparent soft bag 1, the other end intersection perforation mutually between transparent soft bags 1 at different levels, also communicate simultaneously with air pump 24, stopple coupon 17 and the shunt pipe clamp 21 and air filter 19 of band pipe clamp 22 are housed in the branch road that leads to transparent soft bag 1, in the path that leads to air pump 24, are added with branch road pipe clamp 23 and air filter 20.
Device shown in Figure 3, be used for directly connecting combined transparent hose of connection on the transparent soft bag 1 of splendid attire nutrient solution 2, this combined flexible pipe is by annular air strainer 28 be combined intos between an outer tube 25 and pipe core 26 and two pipes, wherein outer tube 25 is by the transparent soft bag 1 inside and outside atmosphere of an annular filter 28 UNICOMs, pipe core 26 1 ends stretch into liquid level 2 depths in the transparent soft bag 1, the other end intersection perforation mutually between transparent soft bags 1 at different levels, also communicate simultaneously with air pump 34, in the branch road that leads to transparent soft bag 1, stopple coupon 27 and the shunt pipe clamp 31 and the air filter 29 of band pipe clamp 32 are housed, in the branch road that leads to air pump 34, are added with branch road pipe clamp 33 and air filter 30.

Claims (4)

1, the simple and easy fermentation unit of a kind of microbial product production, be to connect with the closed tube that is connected with it by a plurality of fermenting containers to combine, it is characterized in that: described fermenting container is transparent soft bag, described closed tube is a transparent hose, be direct connection form between transparent soft bag and the transparent hose in the junction, in this device every is transparent softly to have one to several transparent hoses and its connection perforation.
2, the simple and easy fermentation unit of microbial product production according to claim 1, it is characterized in that going up perforation at the transparent soft bag (1) of splendid attire nutrient solution (2) connects three transparent hoses, they are closed tube (3), closed tube (4) and closed tube (5), wherein: closed tube (3) one ends stretch into transparent soft bag (1) interior nutrient solution (2) and liquid level top, and the other end is added with air filter (7) and pipe clamp (13); Closed tube (4) one ends put in the depths of nutrient solution (2), and the other end communicates with air pump (14) through air filter (8) and air filter (9), and two air filters in pipeline are added with pipe clamp (12) between (8,9); One end of closed tube (5) stretches into nutrient solution (2) depths, and stopple coupon (6) and the shunt pipe clamp (10) of being with pipe clamp (11) are equipped with in the other end intersection perforation mutually between transparent soft bag (1) at different levels on pipe (5) path.
3, the simple and easy fermentation unit of microbial product production according to claim 1, it is characterized in that, transparent soft bag (1) at splendid attire nutrient solution (2) connects two transparent hoses of connection, one is closed tube (15), another is closed tube (16), wherein air filter (18) is equipped with in closed tube (15) upper end, transparent soft bag (1) interior nutrient solution (2) liquid level top is stretched in the lower end, closed tube (16) has an end to stretch into liquid level (2) depths in the transparent soft bag (1), the other end is intersection perforation mutually between transparent soft bags at different levels (1), also communicate simultaneously with air pump (24), stopple coupon (17) and the shunt pipe clamp (21) and the air filter (19) of band pipe clamp (22) are housed in the branch road that leads to transparent soft bag (1), in the branch road that leads to air pump (24), are added with branch road pipe clamp (23) and air filter (20).
4, the simple and easy fermentation unit of microbial product production according to claim 1, it is characterized in that, going up directly at the transparent soft bag (1) of splendid attire nutrient solution (2), perforation connects a combined transparent hose, this combined transparent hose is by annular air strainer (28) be combined between an outer tube (25) and pipe core (26) and two pipes, wherein: outer tube (25) is by the inside and outside atmosphere of the transparent soft bag of an annular filter (28) UNICOM (1), pipe core (26) one ends stretch into transparent soft bag (1) interior liquid level (2) depths, the other end is intersection perforation mutually between transparent soft bags at different levels (1), also communicate simultaneously with air pump (34), in the branch road that leads to transparent soft bag (1), stopple coupon (27) and the shunt pipe clamp (31) and the air filter (29) of band pipe clamp (32) are housed, in the branch road that leads to air pump (34), are added with branch road pipe clamp (33) and air filter (30).
CN 98227774 1998-09-03 1998-09-03 Simple fermentor for producing microbiological products Expired - Fee Related CN2347982Y (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 98227774 CN2347982Y (en) 1998-09-03 1998-09-03 Simple fermentor for producing microbiological products

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 98227774 CN2347982Y (en) 1998-09-03 1998-09-03 Simple fermentor for producing microbiological products

Publications (1)

Publication Number Publication Date
CN2347982Y true CN2347982Y (en) 1999-11-10

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CN 98227774 Expired - Fee Related CN2347982Y (en) 1998-09-03 1998-09-03 Simple fermentor for producing microbiological products

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103881910A (en) * 2014-02-20 2014-06-25 北京科兴中维生物技术有限公司 Aseptic operation pipeline system with external power output
CN110651031A (en) * 2017-03-28 2020-01-03 康宁股份有限公司 Aseptic bioprocess packaging
CN110892056A (en) * 2017-05-23 2020-03-17 瓦伦汀·克雷默 Device and method for culturing cells

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103881910A (en) * 2014-02-20 2014-06-25 北京科兴中维生物技术有限公司 Aseptic operation pipeline system with external power output
CN110651031A (en) * 2017-03-28 2020-01-03 康宁股份有限公司 Aseptic bioprocess packaging
CN110651031B (en) * 2017-03-28 2024-03-29 康宁股份有限公司 Sterile bioprocess packaging
CN110892056A (en) * 2017-05-23 2020-03-17 瓦伦汀·克雷默 Device and method for culturing cells
CN110892056B (en) * 2017-05-23 2023-10-13 奥克生物系统公司 Device and method for culturing cells

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