CN210534169U

CN210534169U - Sample device for full-automatic chemiluminescence immunoassay

Info

Publication number: CN210534169U
Application number: CN201921361516.3U
Authority: CN
Inventors: 母彪; 曾响红; 邱胜聪; 鲜志强; 王鹏
Original assignee: Chengdu Seamaty Technology Co ltd
Current assignee: Chengdu Seamaty Technology Co ltd
Priority date: 2019-08-21
Filing date: 2019-08-21
Publication date: 2020-05-15
Anticipated expiration: 2029-08-21

Abstract

The utility model discloses a full-automatic chemiluminescence immunity analysis is with sample device, including sample carousel, support and sample motor, the sample motor is installed on the support, and the sample carousel is installed on the output shaft of sample motor, and the sample motor drives the sample carousel and rotates, is provided with a plurality of sample cups on the sample carousel and bears the position. The sample cup bearing position is filled with a blood sample, the sample turntable rotates to rotate the sample cup bearing position filled with the sample to the turntable assembly, so that the sample cup bearing position is opposite to the capillary on the turntable assembly, and the capillary sucks the blood sample in the sample cup bearing position into the capillary through the siphoning effect. The utility model discloses only need to put into the device with the blood sample can automatic supply appearance, provide the sample efficiency of supplying, also can be applied to on the full-automatic chemiluminescence immunoassay device.

Description

Sample device for full-automatic chemiluminescence immunoassay

Technical Field

The utility model relates to a biochemical analysis device especially relates to an utilize chemiluminescence method to carry out immunoassay's instrument.

Background

ChemiLuminescence (CL) is a type of molecular luminescence spectroscopy, and is a trace analysis method for determining the content of an analyte by detecting the ChemiLuminescence intensity of a system by using an instrument according to the principle that the concentration of the analyte in a chemical detection system and the ChemiLuminescence intensity of the system are in a linear quantitative relationship under a certain condition. The chemiluminescence method has wide application in the fields of trace metal ions, various inorganic compounds, organic compound analysis and biology.

Chemiluminescence immunoassay (CLIA) is a technique for detecting and analyzing various antigens, antibodies, hormones, enzymes, vitamins, drugs and the like by combining a chemiluminescence assay technique with high sensitivity and a high-specificity immunoreaction. Is an immunoassay technology developed after radioimmunoassay, enzyme immunoassay, fluoroimmunoassay and time-resolved fluoroimmunoassay. The chemiluminescence method has the advantages of high sensitivity, strong specificity, high accuracy, wide detection range and the like. Compared with the semi-quantitative enzyme-linked immunosorbent assay, the chemiluminescence assay is real quantitative, and the detection speed is higher and more convenient. Meanwhile, the chemiluminescent marker is stable, the effective period of the reagent is long, and the requirement of clinical application is greatly facilitated.

When carrying out chemiluminescence immunoassay and detecting, need absorb the blood sample, current mode is artifical through the instrument with the blood sample absorption to the reaction carrier on react, needs artifical manual operation, and operating efficiency is low, can't use on the full-automatic chemiluminescence immunoassay device.

SUMMERY OF THE UTILITY MODEL

In order to overcome the inefficiency that current manual absorption blood sample exists, defect that can not automize, the utility model provides a sample device for full-automatic chemiluminescence immunoassay only needs to put into the device with the blood sample through this sample device can supply appearance automatically, provides the appearance efficiency of supplying, also can be applied to on the full-automatic chemiluminescence immunoassay device.

In order to solve the technical problem, the utility model discloses the technical scheme who adopts is:

a full-automatic chemiluminescence immunoassay sample device is characterized in that: including sample carousel, support and sample motor, the sample motor is installed on the support, and the sample carousel is installed on the output shaft of sample motor, and the sample motor drives the sample carousel and rotates, is provided with a plurality of sample cup on the sample carousel and bears the weight of the position. The sample cup bearing position is filled with a blood sample, the sample turntable rotates to rotate the sample cup bearing position filled with the sample to the turntable assembly, so that the sample cup bearing position is opposite to the capillary on the turntable assembly, and the capillary sucks the blood sample in the sample cup bearing position into the capillary through the siphoning effect.

The bearing positions of the sample cups are four, and the included angle between the bearing positions of two adjacent sample cups is 90 degrees.

The sample cup bearing position is arranged radially, the diameter of the bottom of the cavity at the sample cup bearing position is smaller than that at the opening end, and a wedge-shaped surface is arranged on the outer side face of the opening end at the sample cup bearing position.

The sample device further comprises a support moving mechanism, the support moving mechanism comprises a support motor and a support rail, a support gear is sleeved on an output shaft of the support motor, a support rack is arranged on the support, the support is arranged on the support rail, the support motor rotates to drive the support gear to rotate, and the support gear rotates to drive the support to slide on the support rail.

Compared with the prior art, the utility model discloses following beneficial effect has:

1. the utility model discloses a sample carousel, support and sample motor, the sample motor is installed on the support, and the sample carousel is installed on the output shaft of sample motor, and the sample motor drives the sample carousel and rotates, is provided with a plurality of sample cups on the sample carousel and bears the weight of the position. The sample cup bearing position is filled with a blood sample, the sample turntable rotates to rotate the sample cup bearing position filled with the sample to the capillary, and the capillary sucks the blood sample in the sample cup bearing position into the capillary through the siphoning effect. The user only needs to fall the sample after the centrifugation in the sample cup bears the weight of the position, and when needing the sample, the sample carousel rotates, and the sample cup that will have the blood sample bears the weight of the position and rotates to capillary department can. Need not the manual sample of people, improve sampling efficiency, whole device is simple moreover, send a kind through rotating, and the volume also can reduce, is favorable to whole automatic immunoassay appearance miniaturization like this.

2. The utility model discloses there are four sample cup bearing position, and the contained angle that two adjacent sample cups bear the weight of the position is 90. The sample cup bearing position is arranged, so that continuous feeding, sample loading, preparation, sampling and sample loading preparation can be carried out, and continuous operation can be realized.

3. The utility model discloses the sample cup bears the weight of the radial setting of position, and sample cup bears the weight of position cavity bottom diameter and is less than the diameter of beginning department, sample cup bears position open end lateral surface and is provided with the wedge. Through the setting of structure like this, can let sample cup bear the weight of the position and rotate the capillary after, because the bottom diameter is little, open end diameter is big, and the sample will outwards slowly drip under the effect of gravity to the capillary siphon.

4. The utility model discloses sample device still includes support moving mechanism, and support moving mechanism includes support motor and support track, cup joints a support gear on the output shaft of support motor, installs the support rack on the support, and the support mounting is on the support track, and support motor rotates and drives support gear revolve, and support gear revolve drives the support and slides on the support track. Therefore, the sample device can be moved, and the distance between the sample device and the capillary can be adjusted, so that the capillary can be siphoned conveniently.

Drawings

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a schematic structural diagram of a sample turntable according to the present invention;

FIG. 3 is a schematic view of the half-section of FIG. 2;

FIG. 4 is a schematic structural view of the application of the present invention to a full-automatic chemiluminescence immunoassay device.

Reference numeral 1, a capillary storage component, 2, a capillary pushing-out component, 3, a turntable component, 4, a blowing component, 5, a sample device, 50, a sample turntable, 501, a sample cup bearing position, 51, a bracket, 52, a sample motor, 53, a bracket moving mechanism, 531, a bracket motor, 532, a bracket track, 533, a bracket gear, 534, a bracket rack, 6, a reagent component, 7, a detection component, 8, a bottom plate, 9 and a capillary.

Detailed Description

The present invention will be further described with reference to the following examples, which are only some, but not all, of the examples of the present invention. Based on the embodiments in the present invention, other embodiments used by those skilled in the art without creative work belong to the protection scope of the present invention. The utility model discloses the position word that appears in like "preceding", "back", "left", "right", has only represented relative position relation, all is the description of going on to the position of figure 4 to the position around not necessarily being actual, consequently can not do the restrictive understanding.

The utility model discloses a sample device 5 includes sample carousel 50, support 51 and sample motor 52, and sample motor 52 installs on support 51, and sample carousel 50 installs on sample motor 52's output shaft, and sample motor 52 drives sample carousel 50 and rotates, is provided with a plurality of sample cups on the sample carousel 50 and bears position 501. The centrifuged blood sample is filled in the sample cup bearing position, the sample turntable rotates to rotate the sample cup bearing position filled with the sample to the turntable assembly, so that the sample cup bearing position is opposite to the capillary on the turntable assembly, and the capillary sucks the blood sample in the sample cup bearing position into the capillary through the siphoning effect.

To facilitate adjustment of the spacing between the sample device and the carousel assembly so that the capillary can siphon into the blood sample.

The sample device 5 further comprises a support moving mechanism 53, the support moving mechanism comprises a support motor 531 and a support rail 532, a support gear 533 is sleeved on an output shaft of the support motor 531, a support rack 534 is installed on the support 51, the support 51 is installed on the support rail 532, the support motor 531 rotates to drive the support gear to rotate, and the support gear rotates to drive the support to slide on the support rail.

And the right sides of the sample turntable and the bracket are respectively provided with a position sensor for respectively detecting the bearing position of the sample cup and the bracket, the bearing position of the sample cup is used for determining the rotating angle of the sample turntable, and the bracket is used for determining the moving distance of the bracket.

The utility model provides a full-automatic chemiluminescence immunoassay device, the device's effect is all steps of realizing blood sample chemiluminescence immunoassay, and whole automation mechanized operation, the user only need load the blood sample, and the starting equipment can carry out full automated inspection, the automated generation testing result. The device has the following specific structure:

the method comprises the following steps: capillary storage component 1, capillary push-out component 2, carousel component 3, gas blowing component 4, sample device 5, reagent subassembly 6, detection module 7 and bottom plate 8, above-mentioned subassembly is all installed on bottom plate 8. Their relative positional relationship is: capillary release subassembly 2 is located the left side of capillary storage subassembly 1, carousel subassembly 3 is located the right side of capillary storage subassembly 1, blowing subassembly 4 is located carousel subassembly 3's left side, and blowing subassembly 4 is located capillary storage subassembly 1 and capillary release subassembly 2's front side, and capillary storage subassembly 1 and capillary release subassembly 2 pass through the mounting panel and install in the left side of 3 side parts on carousel subassembly, and the left side in carousel subassembly 3 the latter half is installed to blowing subassembly 4. Sample device 5, reagent subassembly 6 and determine module 7 all are located the right side of carousel subassembly 3, reagent subassembly 6 is located the centre of sample device 5 and determine module 7, and sample device 5 is located the right front side of carousel subassembly, and determine module is located the back right side of carousel subassembly. And a waste liquid groove is arranged below the sample device, the air blowing assembly and the reagent assembly, the waste liquid groove is arranged below the bottom plate, and the waste liquid groove is used for collecting waste liquid generated by the sample device, the air blowing assembly and the reagent assembly.

The capillary tube pushing assembly 2 pushes out the capillary tube in the capillary tube storage assembly 1 and sends the capillary tube to the turntable assembly 3, the turntable assembly 3 rotates to convey the capillary tube 9 to the positions of the sample device 5, the blowing assembly 4, the reagent assembly 6 and the detection assembly 7, the blowing assembly is used for removing residual liquid in the capillary tube 9, the sample device is used for providing a blood sample for the capillary tube, the reagent assembly is used for providing a reagent for the capillary tube, and the detection assembly is used for detecting the number of photons emitted by the detection capillary tube.

Claims

1. A full-automatic chemiluminescence immunoassay sample device is characterized in that: including sample carousel, support and sample motor, the sample motor is installed on the support, and the sample carousel is installed on the output shaft of sample motor, and the sample motor drives the sample carousel and rotates, is provided with a plurality of sample cup on the sample carousel and bears the weight of the position.

2. The device according to claim 1, wherein the sample for full-automatic chemiluminescence immunoassay comprises: the bearing positions of the sample cups are four, and the included angle between the bearing positions of two adjacent sample cups is 90 degrees.

3. The device according to claim 1, wherein the sample for full-automatic chemiluminescence immunoassay comprises: the sample cup bearing position is arranged radially, the diameter of the bottom of the cavity at the sample cup bearing position is smaller than that at the opening end, and a wedge-shaped surface is arranged on the outer side face of the opening end at the sample cup bearing position.

4. The device according to claim 1, wherein the sample for full-automatic chemiluminescence immunoassay comprises: the sample device further comprises a support moving mechanism, the support moving mechanism comprises a support motor and a support rail, a support gear is sleeved on an output shaft of the support motor, a support rack is arranged on the support, the support is arranged on the support rail, the support motor rotates to drive the support gear to rotate, and the support gear rotates to drive the support to slide on the support rail.