CN210534172U

CN210534172U - Full-automatic chemiluminescence immunoassay device

Info

Publication number: CN210534172U
Application number: CN201921361517.8U
Authority: CN
Inventors: 王鹏; 曾响红; 叶芦苇; 母彪; 邱胜聪
Original assignee: Chengdu Seamaty Technology Co ltd
Current assignee: Chengdu Smart Technology Co ltd
Priority date: 2019-08-21
Filing date: 2019-08-21
Publication date: 2020-05-15
Anticipated expiration: 2029-08-21

Abstract

The utility model discloses a full-automatic chemiluminescence immunoassay device, release subassembly, carousel subassembly, the subassembly of blowing, sample subassembly, reagent subassembly and determine module including capillary storage subassembly, capillary, the capillary that the subassembly will be located capillary storage subassembly is released, send the carousel subassembly on, the carousel subassembly rotates and carries sample subassembly, the subassembly of blowing, reagent subassembly and determine module position department with the capillary, the subassembly of blowing is arranged in cleaing away the remaining liquid in the capillary, the sample subassembly is used for providing the blood sample for the capillary, the reagent subassembly is used for providing reagent for the capillary, determine module is used for detecting the luminous photon number of capillary. The utility model discloses the carrier of utilization no longer is current ELIAS plate or micropore board, but utilizes the capillary, and the sample use amount and the reagent use amount that have significantly reduced have still improved detection efficiency when having reduced the detection cost.

Description

Full-automatic chemiluminescence immunoassay device

Technical Field

The utility model relates to a biochemical analysis device especially relates to an utilize chemiluminescence method to carry out immunoassay's instrument.

Background

ChemiLuminescence (CL) is a type of molecular luminescence spectroscopy, and is a trace analysis method for determining the content of an analyte by detecting the ChemiLuminescence intensity of a system by using an instrument according to the principle that the concentration of the analyte in a chemical detection system and the ChemiLuminescence intensity of the system are in a linear quantitative relationship under a certain condition. The chemiluminescence method has wide application in the fields of trace metal ions, various inorganic compounds, organic compound analysis and biology.

Chemiluminescence immunoassay (CLIA) is a technique for detecting and analyzing various antigens, antibodies, hormones, enzymes, vitamins, drugs and the like by combining a chemiluminescence assay technique with high sensitivity and a high-specificity immunoreaction. Is an immunoassay technology developed after radioimmunoassay, enzyme immunoassay, fluoroimmunoassay and time-resolved fluoroimmunoassay. The chemiluminescence method has the advantages of high sensitivity, strong specificity, high accuracy, wide detection range and the like. Compared with the semi-quantitative enzyme-linked immunosorbent assay, the chemiluminescence assay is real quantitative, and the detection speed is higher and more convenient. Meanwhile, the chemiluminescent marker is stable, the effective period of the reagent is long, and the requirement of clinical application is greatly facilitated.

The Chinese utility model patent with the application number of CN201320245554.9, the application date of 2013, 5 and 9 months and the publication date of 2013, 9 and 11 months discloses a full-automatic chemiluminescence immunoassay analyzer. The full-automatic chemiluminescence immunoassay analyzer comprises a frame body and a control system, wherein a sample area, a batten feeding system, an incubation area and a batten detection system are sequentially arranged on the frame body from left to right, a liquid path system is arranged below or on the right side of the incubation area, a reagent area is arranged below the incubation area and below or on the right side of the batten detection system, a sample arm is arranged on the left side of the frame body, a reagent arm is arranged on the right side of the frame body, a first push rod arm is arranged on the frame body above the batten feeding system, a second push rod arm is arranged in the incubation area, and the batten feeding system, the incubation area, the batten detection system, the liquid path system, the sample arm, the reagent arm, the first push rod arm and the second push rod arm are respectively and electrically connected with the control system. The patent discloses that a microplate is used for carrying out the forensic luminescence immunoassay, and the carrier has the defects of large sample loading amount, high detection cost and low detection efficiency.

The Chinese patent application with the application number of CN201711295832.0, the application date of 12 and 8 in 2017 and the publication date of 3 and 23 in 2018 discloses a full-automatic chemiluminescence immunoassay instrument, which comprises the following components in part by weight: the analyzer comprises an analyzer body and an analyzer upper cover; the analyzer body is provided with: an incubation oscillator, a plate washer and an interpretation instrument; the incubation oscillator is positioned in a first preset area, the plate washing machine is positioned in a second preset area, and the interpretation instrument is positioned in a third preset area; further comprising: a controller, a robotic arm; the mechanical arm is used for loading the sample of the ELISA plate under the control of the controller; transferring the enzyme label plate to the first preset area so as to perform incubation operation on the enzyme label plate; transferring the ELISA plate to a second preset area to perform plate washing operation on the ELISA plate; and transferring the ELISA plate to a third preset area so as to read the ELISA plate. The utility model discloses an utilize the ELIAS plate to carry out chemiluminescence immunoassay, so its each station also designs based on the ELIAS plate chemiluminescence step, adopts such carrier to exist equally and to go up the appearance volume great, and the detection cost is higher, the lower defect of detection efficiency.

SUMMERY OF THE UTILITY MODEL

In order to overcome the sample loading volume that above-mentioned full-automatic chemiluminescence immunoassay appearance exists big, detection cost is high, the lower defect of detection efficiency, the utility model provides a full-automatic chemiluminescence immunoassay device, the carrier that this immunoassay device utilized no longer is current ELIAS plate or micropore board, but utilizes the capillary, has significantly reduced sample use amount and reagent use amount, when having reduced detection cost, has still improved detection efficiency.

In order to solve the technical problem, the utility model discloses the technical scheme who adopts is:

a full-automatic chemiluminescence immunoassay device is characterized in that: including capillary storage module, capillary release subassembly, carousel subassembly, the subassembly of blowing, sample subassembly, reagent subassembly and determine module, the subassembly is located the left side of capillary storage module in the capillary, the carousel subassembly is located the right side of capillary storage module, the subassembly of blowing is located the left side of carousel subassembly, sample subassembly, reagent subassembly and determine module all are located the right side of carousel subassembly, the reagent subassembly is located the centre of sample subassembly and determine module, and capillary release subassembly will be located the capillary in capillary storage module and release, send the carousel subassembly to, the carousel subassembly rotates and carries sample subassembly, the subassembly of blowing, reagent subassembly and determine module position department with the capillary, the subassembly of blowing is used for cleaing away the remaining liquid in the capillary, the sample subassembly is used for providing the blood sample for the capillary, the reagent assembly is used for providing reagents for the capillary, and the detection assembly is used for detecting the number of photons emitted by the capillary.

The capillary storage component comprises a capillary box and a translation mechanism, wherein the capillary box is arranged on the translation mechanism, and the capillary box translates back and forth under the action of the translation mechanism.

The capillary tube box comprises a box body, the box body forms a capillary tube cavity through a plurality of partition plates, a plurality of capillary tubes are arranged in the capillary tube cavity, a plurality of left side through holes are formed in the bottom of the left side of the box body, a plurality of right side through holes are formed in the right side of the bottom of the box body, one capillary tube cavity is provided with one left side through hole and one right side through hole, and the left side through hole and the right side through hole are respectively communicated with the.

The translation mechanism comprises a linear rail, a machine base and a translation motor, a translation gear is sleeved on an output shaft of the translation motor, a translation rack is installed on the machine base and meshed with the translation gear and the translation rack, the machine base is installed on the linear rail, the translation motor rotates to drive the translation gear to rotate, the translation gear rotates to drive the translation rack to drive the machine base to slide on the linear rail, and the capillary tube box is fixed on the machine base and translates back and forth on the linear rail along with the machine base.

The capillary tube pushing assembly comprises a positioning mechanism, a pushing mechanism and a pushing rail, the positioning mechanism comprises a positioning base, a positioning head and a positioning motor, the positioning base is installed on the pushing rail, a positioning gear is installed on an output shaft of the positioning motor, a positioning rack is installed on the positioning base, the positioning gear is meshed with the positioning rack, the positioning head is installed on the positioning base, the pushing mechanism comprises a pushing motor, a pushing base and a pushing rod, the pushing base is installed on the pushing rail, the pushing gear is installed on the output shaft of the pushing motor, the pushing rack is installed on the pushing base, the pushing gear is meshed with the pushing rack, the pushing rod is installed on the pushing base, the pushing base is located on the left side of the positioning base, the pushing rod penetrates through the positioning base and the positioning head, and the positioning head can be extended out by the. The motion relationship is as follows: the positioning motor rotates positively to drive the positioning gear to rotate, so that the positioning base is driven to move rightwards on the push-out rail, the positioning base drives the positioning head to move rightwards to be close to the capillary tube box, the positioning head extends into the left through hole of the capillary tube box, then the positioning motor stops rotating, the push-out motor rotates positively to drive the push-out gear to rotate, so that the push-out base is driven to move rightwards on the push-out rail, the push-out base drives the push-out rod to move rightwards, the push-out rod extends out of the positioning head and extends into the capillary tube cavity to push out the right through hole of the capillary tube to the turntable assembly, and the push-out. After the capillary tube is pushed out, the pushing motor rotates reversely to drive the pushing rod to reset, the positioning motor rotates reversely to drive the positioning head to reset to prepare for entering the next pushing action, and the capillary tube pushing action is realized through the circulating action. If the capillaries in one capillary cavity in the capillary box are all pushed out, the capillary box moves forwards for a certain distance, and the next left through hole is aligned with the positioning head.

The carousel subassembly includes incubation carousel and rotation motor, and the incubation carousel dress is on rotating the motor, rotates the rotation motor drive incubation carousel and rotates, is provided with a plurality of capillary bearing holes on the incubation carousel. After being pushed out from the capillary box, the capillary is sent into the capillary bearing hole so as to facilitate the rotation of the incubation rotating disc and drive the capillary to rotate to a required position.

Install the spring leaf on the right side of incubation carousel, through the effect of spring leaf elasticity with the capillary spacing in capillary bearing hole, avoid the capillary to fall from the incubation carousel at the pivoted in-process, cause the capillary to damage.

The specific structure of the incubation turntable comprises a turntable body, heat preservation cotton and an electric heating film, wherein the electric heating film is wound on the turntable body, the heat preservation cotton is wound on the electric heating film, the capillary is heated through the electric heating film to provide proper incubation temperature, and the heat preservation cotton plays a role in heat insulation and heat preservation, so that the incubation turntable not only plays a role in transferring the capillary, but also plays a role in incubating the capillary. Certainly, in order to ensure the proper incubation temperature of the capillary, a temperature sensor is also arranged on the disc body, so that the incubation temperature can be detected at any time, and the constant temperature of the incubation rotary disc can be ensured.

The blowing assembly comprises a rubber blowing nozzle and a driving mechanism, the rubber blowing nozzle is installed on the driving mechanism, the driving mechanism can drive the rubber blowing nozzle to move towards the turntable assembly, the rubber blowing nozzle collides against the turntable assembly under the action of the driving mechanism, and the gas is deformed and compressed to be blown into the capillary tube so as to blow away residues in the capillary tube.

The driving mechanism can be realized by an air cylinder, an oil cylinder or a structure combining a gear rack and a motor.

The utility model provides a concrete structure of this actuating mechanism:

actuating mechanism includes the electromagnetism iron frame, electromagnet core and electromagnet frame, electromagnet core installs in the electromagnet frame, the electromagnet frame is fixed on the electromagnet frame, the electromagnet frame can be stretched out to electromagnet core one end, the rubber blowing nozzle is fixed in the one end that electromagnet core stretched out the electromagnet frame, after the electromagnet core circular telegram, electromagnet core produces magnetism, the incubation carousel is the iron material, electromagnet core drives the striking of rubber blowing nozzle on the incubation carousel under the effect of magnetic force, compressed gas blows off the remaining liquid in the capillary. In order to realize the reset of the electromagnetic iron core, a reset spring is sleeved on the electromagnetic iron core, and the reset spring drives the electromagnetic iron core to reset after the electromagnetic iron core is powered off.

In order to realize that the turntable assembly can drive the capillary tube to rotate to the position of the air blowing assembly, the air blowing assembly comprises a position sensor, the position sensor is installed at the position of the rubber air blowing nozzle and used for detecting whether the capillary tube is arranged in a capillary tube bearing hole aligned to the rubber air blowing nozzle or not, and when the capillary tube is arranged, the electromagnet is connected with a power supply to enable the rubber air blowing nozzle to impact the turntable assembly. Certainly, a position sensor is not needed, and the rotation angle of the rotary disc required to rotate can be calculated only after the air blowing assembly is installed, and the capillary tube can also be positioned.

The sample assembly comprises a sample turntable, a support and a sample motor, the sample motor is mounted on the support, the sample turntable is mounted on an output shaft of the sample motor, the sample motor drives the sample turntable to rotate, and a plurality of sample cup bearing positions are arranged on the sample turntable. The sample cup bearing position is filled with a blood sample, the sample turntable rotates to rotate the sample cup bearing position filled with the sample to the turntable assembly, so that the sample cup bearing position is opposite to the capillary on the turntable assembly, and the capillary sucks the blood sample in the sample cup bearing position into the capillary through the siphoning effect.

The sample assembly further comprises a support moving mechanism, the support moving mechanism comprises a support motor and a support rail, a support gear is sleeved on an output shaft of the support motor, a support rack is arranged on the support, the support is arranged on the support rail, the support motor rotates to drive the support gear to rotate, and the support gear rotates to drive the support to slide on the support rail.

The reagent assembly comprises a reagent cup, a reagent cup turntable and a reagent extrusion mechanism, the interior of the reagent cup is divided into a plurality of reagent cavities, a plurality of reagent outlet pipes are arranged on the outer circumference of the reagent cup, one reagent cavity is provided with one reagent outlet pipe, the reagent outlet pipe is communicated with the reagent cavity, the reagent cup turntable is connected onto the reagent cup, a rubber film is arranged at the joint of the reagent turntable and the reagent cup and used for sealing the reagent cavity (ensuring that the reagent can only be extruded out of the reagent outlet pipe and can not flow out of the other end of the reagent cavity), the reagent turntable is provided with a plurality of through holes and a transmission groove, the number of the through holes is the same as that of the reagent cavities, each through hole is respectively communicated with one reagent cavity, the transmission groove is sleeved on an output shaft of a motor, the motor drives the reagent cup turntable to rotate, the reagent extrusion mechanism comprises an extrusion rod and a power source, and the extrusion rod is connected, Cylinder, oil cylinder, electric push rod, etc.) and the extrusion rod is extruded on the rubber membrane from the through-hole under the effect of power supply, extrudes the reagent from the reagent outlet pipe through the reagent in the rubber membrane deformation extrusion reagent chamber. The extrusion rod is pushed to extrude the rubber membrane, and the reagent in the reagent cavity is extruded out through the deformation of the rubber membrane. Because a plurality of reagent cavities are arranged in the reagent cup, one reagent is stored in each reagent cavity, when the reagent needs to be extruded, the rotating motor rotates, the reagent cavity with the reagent is aligned to the extrusion rod, and then the extrusion rod acts to extrude the reagent. In order to accurately position whether the required reagent chamber is aligned with the extrusion rod, a sensor can be arranged at the extrusion rod to detect whether the reagent chamber is aligned with the extrusion rod.

In order to facilitate the adjustment of the distance between the reagent assembly and the turntable assembly and facilitate capillary siphon reagent, the reagent assembly further comprises a reagent mounting seat, a reagent line rail and a reagent motor, a reagent gear is sleeved on an output shaft of the reagent motor, a reagent rack is mounted on the reagent mounting seat and meshed with the reagent rack, and the reagent mounting seat is mounted on the reagent line rail and slides on the reagent line rail under the action of the reagent motor. The reagent turntable, the rotating motor and the power source are all installed on the reagent installation seat, and thus the reagent cup, the reagent turntable, the rotating motor and the power source slide on the reagent line rail along with the reagent installation seat. The distance between the reagent assembly and the turntable assembly is integrally adjusted, and the capillary tube is ensured to siphon the reagent into the capillary tube.

In order to detect the size of the reagent droplets, a reagent droplet size detection sensor (detection optocoupler) is arranged below the reagent cup, the detected size information of the reagent droplets is fed back to a controller of a power source, then the power source controls the action of an extrusion rod, and the extrusion rod is not extruded any more after the reagent droplets with proper size are extruded.

The reagent cup is clamped on the reagent cup rotary table through the reagent cup shell, the clamping bulge is arranged on the reagent cup shell, the clamping groove is arranged on the reagent cup rotary table, after the clamping bulge is embedded into the clamping groove, the reagent cup shell is fixed in the axial direction and the radial direction, and the reagent cup is sleeved on the reagent cup shell.

The detection assembly comprises a tube pushing mechanism, a photoelectric detector and a tube supporting mechanism, the tube pushing mechanism is installed on the left side of the rotary disc assembly and used for pushing the capillary tube on the rotary disc assembly out of the tube supporting mechanism, the tube supporting mechanism is located at a detection port of the photoelectric detector and used for conveying the capillary tube into the photoelectric detector for detection, and after detection is finished, the capillary tube is lifted out of the photoelectric detector and released.

The structure of the push pipe mechanism is consistent with that of the push pipe assembly. The purpose of which is to allow the capillary to pass from the turret assembly to the escrow mechanism.

The pipe supporting mechanism comprises a bracket I, a bracket II, a bracket I driving mechanism and an impact plate, the bracket II penetrates through a movable bracket I, the bracket I driving mechanism comprises a bracket motor and a bracket linear rail, the bracket I is installed on the bracket linear rail, a bracket gear is installed on an output shaft of the bracket motor, a bracket rack is installed on the bracket I, the bracket gear is meshed with the bracket rack, the bracket motor rotates to drive the bracket gear to rotate, the bracket gear rotates to drive the bracket rack to move, so that the bracket I is pushed to move on the bracket linear rail, the bracket I is provided with a bracket pipe part, the bracket II is provided with a bracket pipe part and a spring part, the spring part is provided with a spring, the other end of the spring is abutted against the bracket I, under the action force of the spring, the pipe supporting part of the bracket I and the pipe supporting part of the bracket II are abutted together to form a V-shaped groove, the, the bracket II can impact on the impact plate.

The capillary tube is pushed into a V-shaped groove formed by a bracket I and a bracket II by a tube pushing mechanism, then a bracket motor rotates to send the capillary tube into a photoelectric detector for detection, after the detection is finished, the bracket motor rotates to send the capillary tube out of the photoelectric detector and then continuously rotates until the bracket II impacts on an impact plate, the bracket motor stops rotating, the bracket II can move towards the photoelectric detector under the action of impact force, the bracket I does not move, at the moment, the bracket I is separated from the bracket II, the V-shaped groove is separated, the capillary tube falls from the V-shaped groove, then the bracket motor rotates reversely, the bracket I moves towards the photoelectric detector and leaves the impact plate, under the action force of a spring, the bracket II returns to the original position to form the V-shaped groove, the bracket motor continuously rotates until the bracket I returns to the original position to stop rotating, and the next capillary tube.

The tube supporting mechanism further comprises a capillary tube collecting box, the capillary tube collecting box is located below the bracket I and the bracket II, and the impact plate is installed in the capillary tube collecting box.

The utility model discloses an action relation as follows:

starting the instrument, moving a capillary tube box of a capillary tube storage assembly to a capillary tube pushing-out part, extending a positioning head of the capillary tube pushing-out part, extending the positioning head into a through hole on the left side of the capillary tube box for positioning, extending a pushing-out rod out of the positioning head after the positioning is finished, entering a capillary tube cavity of the capillary tube box, pushing the capillary tube out of a capillary tube bearing hole of a turntable assembly, returning the pushing-out rod, returning the positioning head, rotating an incubation turntable of the turntable assembly, rotating to a sample assembly position, rotating the incubation turntable after the incubation time is reached (certainly, the incubation turntable can rotate after the incubation time is reached, and also can rotate in the incubation time as long as the incubation time is ensured), rotating a sample turntable of the sample assembly, rotating a sample cup bearing position where a blood sample is stored to a capillary tube position, sucking the blood sample into the capillary tube through a siphon effect, and incubating the capillary tube in the incubation turntable, the temperature cultivation rotary disc rotates, the capillary tube is sent to the position of the air blowing assembly, the air blowing assembly is electrified, the rubber air blowing nozzle impacts on the temperature cultivation rotary disc, the rubber air blowing nozzle deforms and compresses, compressed air is blown into the capillary tube, residual liquid in the capillary tube is blown off, then the temperature cultivation rotary disc continues to rotate, the temperature cultivation rotary disc rotates to the position of the reagent assembly, the reagent assembly extrudes cleaning liquid drops, the capillary tube sucks cleaning liquid through siphoning action, then the capillary tube rotates to the position of the air blowing assembly to blow air, after repeated multiple times, the capillary tube rotates to the position of the reagent assembly after cleaning is finished, the reagent assembly extrudes reactants, the temperature cultivation is carried out after the capillary tube sucks the reactants, then the capillary tube rotates to the position of the air blowing assembly to blow air, then the cleaning liquid is sucked to the position of the reagent assembly, after repeated multiple times, luminous substrates are sucked, the, the tube pushing mechanism is started, the capillary tube is pushed out from the incubation rotating disc and sent to a V-shaped groove formed by the bracket I and the bracket II, the bracket motor is started, the capillary tube is sent into the photoelectric detector by the bracket I and the bracket II to be detected, after the detection is finished, the capillary tube is sent out by the motor in a rotating mode until the bracket II collides with the impact plate, the capillary tube drops, the motor rotates, the bracket I and the bracket II move towards the position of the photoelectric detector and return to the initial position, and the next capillary tube is prepared to be sent into the capillary tube. The utility model discloses well concrete washing liquid washs the number of times and blows the number of times and is different according to the detection sample of difference.

Compared with the prior art, the utility model discloses following beneficial effect has:

1. the utility model discloses a cooperation of above-mentioned subassembly realizes based on the full-automatic chemiluminescence immunoassay of capillary, and the blood sample after will being equipped with the centrifugation is put in the sample cup bears the weight of the position, and starting drive can realize the full-automatic chemiluminescence immunoassay of blood sample, does not need artifical the participation, has improved analysis efficiency. And the whole detection is based on the capillary tube which is used as a reflecting carrier instead of a micropore plate or an enzyme label plate, so that the sample loading amount and the reagent usage amount can be greatly reduced, the detection cost is reduced, and the detection efficiency is improved. The whole device is precise in matching, compact in installation, small in occupied space and more miniaturized.

2. Capillary storage subassembly includes capillary box and translation mechanism, and the capillary box is installed on translation mechanism, and the capillary box is translation around under translation mechanism's effect. The function of the capillary storage assembly is to provide capillaries. The capillary tube box comprises a box body, the box body forms a capillary tube cavity through a plurality of partition plates, a plurality of capillary tubes are arranged in the capillary tube cavity, a plurality of left side through holes are formed in the bottom of the left side of the box body, a plurality of right side through holes are formed in the right side of the bottom of the box body, one capillary tube cavity is provided with one left side through hole and one right side through hole, and the left side through hole and the right side through hole are respectively communicated with the. The through hole on the left side is used for positioning the positioning head of the capillary tube pushing assembly, and the pushing rod extends into the through hole to push the capillary tube out.

3. The utility model discloses capillary release subassembly includes positioning mechanism, ejecting mechanism and push away the rail, and positioning mechanism includes location frame, location head and positioning motor, and the location frame is installed on pushing away the rail, installs the location gear on positioning motor's the output shaft, installs the location rack on the location frame, location gear and location rack toothing, and the location head is installed on the frame of location, ejecting mechanism is including releasing the motor, releasing the frame and push away the pole, and the release frame is installed on pushing away the rail, installs the release gear on the output shaft of release motor, installs the release rack on the release frame, and the release gear meshes with the release rack, and the push away the pole and installs on the release frame, and the release frame is located the left side of location frame, and the push away pole passes location frame and location head, and the push away pole can stretch out the location head. The capillary tube box is positioned through the positioning head and then pushed out through the push-out rod, the structure has the advantages that the capillary tube box can be positioned, the push-out rod can be guaranteed to push out the capillary tube, meanwhile, the push-out rod can be protected, and deviation and deformation of the push-out rod in the moving process are avoided.

4. Carousel subassembly includes the incubation carousel and rotates the motor, and the incubation carousel dress rotates motor drive incubation carousel rotation on rotating the motor, is provided with a plurality of capillary bearing holes on the incubation carousel. After being pushed out from the capillary box, the capillary is sent into the capillary bearing hole so as to facilitate the rotation of the incubation rotating disc and drive the capillary to rotate to a required position. The utility model provides a carousel subassembly has not only played the effect that the capillary was accurate to be transported to each station, but also has played the effect of incubation device, transports the capillary through rotating, forms the annular station, more can reduce the volume of whole instrument, transports easier control moreover.

5. The utility model discloses the subassembly of blowing includes rubber blowing nozzle and actuating mechanism, and rubber blowing nozzle installs on actuating mechanism, and actuating mechanism can drive rubber blowing nozzle and move towards the carousel subassembly, and under actuating mechanism's effect, rubber blowing nozzle hits on the carousel subassembly, and the deformation compression gas is blown in the capillary, blows away the residue in the capillary. The utility model provides a subassembly of blowing can be without the air feed for current subassembly of blowing, has reduced air supply system, has simplified equipment to can reduce the volume of equipment.

6. The utility model discloses the sample subassembly includes sample carousel, support and sample motor, and the sample motor is installed on the support, and the sample carousel is installed on the output shaft of sample motor, and the sample motor drives the sample carousel and rotates, is provided with a plurality of sample cups on the sample carousel and bears the weight of the position. The sample cup bearing position is filled with a blood sample, the sample turntable rotates to rotate the sample cup bearing position filled with the sample to the turntable assembly, so that the sample cup bearing position is opposite to the capillary on the turntable assembly, and the capillary sucks the blood sample in the sample cup bearing position into the capillary through the siphoning effect. Compared with the existing sample assembly, the sample assembly structure is simple in structure, does not need to manually suck a sample, and is simple and convenient to operate.

7. The reagent assembly of the utility model comprises a reagent cup, a reagent cup turntable and a reagent extrusion mechanism, the interior of the reagent cup is divided into a plurality of reagent cavities, a plurality of reagent outlet pipes are arranged on the outer circumference of the reagent cup, one reagent cavity is provided with one reagent outlet pipe, the reagent outlet pipe is communicated with the reagent cavity, the reagent cup turntable is connected on the reagent cup, the reagent turntable is provided with a plurality of through holes and a transmission groove, the number of the through holes is the same as that of the reagent cavities, each through hole is respectively communicated with one reagent cavity, the transmission groove is sleeved on the output shaft of a motor, the motor drives the reagent cup turntable to rotate, the reagent extrusion mechanism comprises an extrusion rod and a power source, the extrusion rod is connected with the power source, under the action of a power source, the extrusion rod extends into the through hole to be extruded on the rubber membrane, and the reagent in the reagent cavity is extruded through the deformation of the rubber membrane, so that the reagent is extruded from the reagent outlet pipe. The extrusion rod is pushed to extrude the rubber die to deform, and the reagent in the reagent cavity is extruded out. Because a plurality of reagent cavities are arranged in the reagent cup, one reagent is stored in each reagent cavity, when the reagent needs to be extruded, the rotating motor rotates, the reagent cavity with the reagent is aligned to the extrusion rod, and then the extrusion rod acts to extrude the reagent. The utility model discloses a reagent subassembly is for prior art, can provide extruding of multiple reagent, the capillary siphon of being convenient for. And the size of the extruded reagent droplets can be checked, and the reagent droplets with proper size can be extruded without causing waste of the reagent droplets.

8. The utility model discloses detection assembly includes ejector sleeve mechanism, photoelectric detector and trusteeship mechanism, and ejector sleeve mechanism installs in carousel subassembly left side, with the capillary on the carousel subassembly release trusteeship mechanism on, trusteeship mechanism is located photoelectric detector's detection mouth department, trusteeship mechanism detects in sending the photoelectric detector with the capillary, has detected the back, holds in the palm out photoelectric detector with the capillary, releases the capillary. The feeding, the sending and the releasing actions of the capillary tube can be realized through the action of the detection assembly, and the full-automatic operation is realized.

Drawings

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a schematic structural view of a capillary storage module according to the present invention;

FIG. 3 is a schematic view of another view direction structure of the capillary storage module of the present invention;

fig. 4 is a schematic structural view of the capillary tube ejecting assembly of the present invention;

FIG. 5 is a schematic structural view of the turntable assembly of the present invention;

FIG. 6 is a schematic view of another view direction structure of the turntable assembly of the present invention

FIG. 7 is a schematic structural view of the blowing assembly of the present invention;

fig. 8 is a schematic structural diagram of the sample assembly of the present invention;

FIG. 9 is a schematic view of the reagent assembly of the present invention;

FIG. 10 is a schematic view of another view direction of the reagent assembly of the present invention;

FIG. 11 is a schematic view of the reagent cup of the present invention;

FIG. 12 is a schematic view of the structure of the rubber film on the reagent cup cover of the present invention;

FIG. 13 is a schematic view of the structure of the reagent cup housing of the present invention;

FIG. 14 is a schematic view of the reagent cup turntable structure of the present invention;

FIG. 15 is a schematic view of the mounting position of the tube pushing mechanism of the present invention;

fig. 16 is a schematic view of the structure of the installation position of the detection device of the present invention;

FIG. 17 is a schematic structural view of the detecting device of the present invention;

fig. 18 is a schematic structural view of the tube supporting mechanism of the present invention;

fig. 19 is a schematic structural view of the bracket ii of the present invention.

Reference numeral 1, a capillary storage component, 10, a capillary cartridge, 101, a cartridge body, 102, a left through hole, 103, a right through hole, 11, a translation mechanism, 111, a wire rail, 112, a base, 113, a translation motor, 114, a translation gear, 115, a translation rack, 2, a capillary pushing-out component, 20, a pushing-out rail, 21, a positioning base, 22, a positioning head, 23, a positioning motor, 24, a positioning gear, 25, a positioning rack, 26, a pushing-out motor, 27, a pushing-out base, 28, a pushing-out rod, 29, a pushing-out gear, 210, a pushing-out rack, 3, a turntable component, 30, an incubation turntable, 301, a tray body, 302, heat preservation cotton, 303, an electric heating film, 31, a rotation motor, 32, a capillary bearing hole, 33, a spring leaf, 4, a blowing component, 40, a rubber blowing nozzle, 41, a driving mechanism, 410, an electromagnetic iron frame, 411, an electromagnetic iron core, 412 and an, 5. sample assembly, 50, sample carousel, 501, sample cup bearing position, 51, rack, 52, sample motor, 53, rack moving mechanism, 531, rack motor, 532, rack rail, 533, rack gear, 534, rack, 6, reagent assembly, 60, reagent cup, 61, reagent cup carousel, 62, reagent pressing mechanism, 63, reagent chamber, 64, reagent outlet tube, 65, motor, 66, pressing rod, 67, power source, 68, mount, 69, reagent track, 610, reagent motor, 611, reagent gear, 612, reagent rack, 613, reagent cup housing, 614, droplet size detection sensor, 615, rubber membrane, 7, detection assembly, 70, push tube mechanism, 71, photodetector, 72, escrow mechanism, 721, carrier i, 722, carrier ii, 723, strike plate, 724, carrier motor, 725, carrier track, 726, rack moving mechanism, 531, reagent cup housing, and carrier motor, Bracket gear, 727, bracket rack, 728, spring, 729, V-shaped groove, 7210, capillary tube collection box, 8, bottom plate, 9, capillary tube.

Detailed Description

The present invention will be further described with reference to the following examples, which are only some, but not all, of the examples of the present invention. Based on the embodiments in the present invention, other embodiments used by those skilled in the art without creative work belong to the protection scope of the present invention. The utility model discloses the position word that appears in like "preceding", "back", "left", "right", has only represented relative position relation, all is the description of going on to the position of figure 1 to the position around not necessarily being actual, consequently can not do the restrictive understanding.

The utility model provides a full-automatic chemiluminescence immunoassay device, the device's effect is all steps of realizing blood sample chemiluminescence immunoassay, and whole automation mechanized operation, the user only need load the blood sample, and the starting equipment can carry out full automated inspection, the automated generation testing result. The device has the following specific structure:

the method comprises the following steps: capillary storage subassembly 1, capillary push-out subassembly 2, carousel subassembly 3, gas blowing subassembly 4, sample subassembly 5, reagent subassembly 6, detection module 7 and bottom plate 8, above-mentioned subassembly is all installed on bottom plate 8. Their relative positional relationship is: capillary release subassembly 2 is located the left side of capillary storage subassembly 1, carousel subassembly 3 is located the right side of capillary storage subassembly 1, blowing subassembly 4 is located carousel subassembly 3's left side, and blowing subassembly 4 is located capillary storage subassembly 1 and capillary release subassembly 2's front side, and capillary storage subassembly 1 and capillary release subassembly 2 pass through the mounting panel and install in the left side of 3 side parts on carousel subassembly, and the left side in carousel subassembly 3 the latter half is installed to blowing subassembly 4. Sample subassembly 5, reagent subassembly 6 and determine module 7 all are located the right side of carousel subassembly 3, reagent subassembly 6 is located the centre of sample subassembly 5 and determine module 7, and sample subassembly 5 is located the right front side of carousel subassembly, and determine module is located the back right side of carousel subassembly. And a waste liquid groove is arranged below the sample assembly, the air blowing assembly and the reagent assembly, the waste liquid groove is arranged below the bottom plate, and the waste liquid groove is used for collecting waste liquid generated by the sample assembly, the air blowing assembly and the reagent assembly.

The capillary tube pushing assembly 2 pushes out the capillary tube in the capillary tube storage assembly 1 and sends the capillary tube to the turntable assembly 3, the turntable assembly 3 rotates to convey the capillary tube 9 to the positions of the sample assembly 5, the blowing assembly 4, the reagent assembly 6 and the detection assembly 7, the blowing assembly is used for removing residual liquid in the capillary tube 9, the sample assembly is used for providing a blood sample for the capillary tube, the reagent assembly is used for providing a reagent for the capillary tube, and the detection assembly is used for detecting the number of photons emitted by the detection capillary tube.

Each component is described in detail below.

The capillary storage assembly 1, its function is to provide coated capillaries. The capillary tube storage assembly comprises a capillary tube box 10 and a translation mechanism 11 for driving the capillary tube box, as shown in fig. 1, the translation mechanism drives the capillary tube box 10 to translate back and forth, the structure of the translation mechanism can be various, such as an air cylinder, an oil cylinder, an electric push rod and the like, as long as the capillary tube box can be pushed to move towards the position of the capillary tube push-out assembly.

The capillary tube box 10 comprises a rectangular box body 101, the box body 101 forms a capillary tube cavity (for storing more capillary tubes) through a plurality of partition plates, a plurality of capillary tubes are arranged in the capillary tube cavity (one capillary tube cavity is equivalent to a cartridge clip), a plurality of left side through holes 102 are formed in the bottom of the left side of the box body 101, a plurality of right side through holes 103 are formed in the right side of the bottom of the box body 101, one capillary tube cavity is provided with one left side through hole and one right side through hole, and the left side through hole and the right side through hole are respectively communicated with. The capillary tubes are arranged in the capillary tube cavity from top to bottom, the width of the capillary tube cavity is slightly larger than the diameter of the capillary tube, and under the action of gravity, the capillary tube at the bottom is pushed out, and then the previous capillary tube falls down.

The utility model provides a translation mechanism's a concrete structure, it includes linear rail 111, frame 112 and translation motor 113, cup joint a translation gear 114 on translation motor 113's the output shaft, install translation rack 115 on frame 112, translation gear 114 and the meshing of translation rack 115, frame 112 is installed on linear rail 111, the linear rail fore-and-aft direction is laid, translation motor rotates, drive translation gear revolve, translation gear revolve drive translation rack drive chassis slides on the linear rail, capillary box 10 fixes on frame 112, along with the frame translation around on the linear rail. In order to ensure that the capillary cartridge can be accurately positioned, a position sensor can be arranged at the capillary pushing-out assembly and used for detecting whether the capillary cartridge is positioned or not.

The translation mechanism is used for rightly facing the left through hole of the capillary cavity with the capillary tube in the box body to the capillary tube pushing-out assembly, so that the capillary tube pushing-out assembly can push out the capillary tube in the capillary cavity from the right through hole to the rotary disc assembly. If the capillary box only has one capillary cavity, a translation mechanism is not needed, and only the through hole on the left side is aligned with the capillary to push out the assembly during installation.

The capillary tube pushing assembly is used for pushing the capillary tubes in the capillary tube box out onto the turntable assembly. Since the capillary cartridge may not be properly positioned due to the translation motor after it is moved into position, it is desirable that the capillary push-out assembly be added with a repositioning process. When the capillary chamber of the capillary cartridge is small, the diameter of the ejector rod is also small, which may cause the ejector rod to be easily deformed, and therefore, it is also necessary to add an arrangement for preventing the ejector rod from being deformed. Therefore, the capillary tube ejector is designed correspondingly, and the specific steps are as follows:

the capillary tube pushing assembly comprises a positioning mechanism, a pushing mechanism and a pushing rail 20, the positioning mechanism comprises a positioning base 21, a positioning head 22 and a positioning motor 23, the positioning base 21 is installed on the pushing rail 20, a positioning gear 24 is installed on an output shaft of the positioning motor 23, a positioning rack 25 is installed on the positioning base 21, the positioning gear 24 is meshed with the positioning rack 25, the positioning head 22 is installed on the positioning base 21, and the positioning head 22 is of a conical structure. The pushing mechanism comprises a pushing motor 26, a pushing base 27 and a pushing rod 28, the pushing base 27 is mounted on the pushing rail 20, a pushing gear 29 is mounted on an output shaft of the pushing motor 26, a pushing rack 210 is mounted on the pushing base 27, the pushing gear 29 is meshed with the pushing rack 210, the pushing rod 28 is mounted on the pushing base 27, the pushing base 27 is located on the left side of the positioning base 21, the pushing rod 28 penetrates through the positioning base 21 and the positioning head 22, and the pushing rod 28 can extend out of the positioning head 22. The motion relationship is as follows: the positioning motor rotates positively to drive the positioning gear to rotate, so that the positioning base is driven to move rightwards on the push-out rail, the positioning base drives the positioning head to move rightwards to be close to the capillary tube box, the positioning head extends into the left through hole of the capillary tube box, then the positioning motor stops rotating, the push-out motor rotates positively to drive the push-out gear to rotate, so that the push-out base is driven to move rightwards on the push-out rail, the push-out base drives the push-out rod to move rightwards, the push-out rod extends out of the positioning head and extends into the capillary tube cavity to push out the right through hole of the capillary tube to the turntable assembly, and the push-out. After the capillary tube is pushed out, the pushing motor rotates reversely to drive the pushing rod to reset, the positioning motor rotates reversely to drive the positioning head to reset to prepare for entering the next pushing action, and the capillary tube pushing action is realized through the circulating action. If the capillaries in one capillary cavity in the capillary box are all pushed out, the capillary box moves forwards for a certain distance, and the next left through hole is aligned with the positioning head.

The capillary tube pushing assembly 2 is only a specific embodiment, and the capillary tube pushing assembly may be of other structures as long as the capillary tube can be pushed out from the capillary tube box through the movement relationship, for example, an air cylinder (one air cylinder is divided into two independent parts, one part drives the positioning head, and the other part drives the pushing rod, or two air cylinders), an oil cylinder structure (the oil cylinder and the air cylinder), or belt transmission (a motor drives a belt to rotate, the belt drives a shaft to rotate, a roller is installed on the shaft, and the positioning base or the pushing base is installed on the shaft) is changed without gear and rack transmission.

The rotary disc assembly has two functions, one is a capillary transfer function for transferring the capillary to each assembly for corresponding action, and the other is an incubation function for replacing an incubation device. The advantages are that: the rotary disc is an annular station, so that the volume of the equipment can be reduced, and the device is reduced, the equipment is optimized and the volume of the equipment is reduced by replacing an incubation device.

The main component of the rotating disc assembly 3 is an incubation rotating disc 30, which is rotated by a rotating motor 31, and a plurality of capillary bearing holes 32 are arranged on the incubation rotating disc. After the capillary tube is pushed out of the capillary cartridge, it is sent into the capillary bearing hole 32, so that the incubation turntable rotates to drive the capillary tube to rotate to a required position.

Install spring leaf 33 at the right side of incubation carousel, through spring leaf 33 effect with capillary spacing in capillary bearing hole 32, avoid the capillary to fall from incubation carousel in the pivoted in-process, cause the capillary to damage.

The specific structure of the incubation rotating disc 30 comprises a disc body 301, heat preservation cotton 302 and an electric heating film 303, wherein the electric heating film 303 is wound on the disc body, the heat preservation cotton 302 is wound on the electric heating film 303, the electric heating film is used for heating to provide proper incubation temperature for the capillary, and the heat preservation cotton plays a role in heat insulation, so that the incubation rotating disc not only plays a role in transporting the capillary, but also plays a role in incubating the capillary. Certainly, in order to ensure the proper incubation temperature of the capillary, a temperature sensor is also arranged on the disc body, so that the incubation temperature can be detected at any time, and the constant temperature of the incubation rotary disc can be ensured.

The rotation motor 31 is installed at the left side of the incubation carousel 30 below the capillary push-out assembly.

The blowing assembly has the function of realizing blowing action and cleaning the residual liquid in the capillary tube. The subassembly of blowing can adopt current structure of blowing, certainly the utility model discloses a simplify equipment, designed the subassembly of blowing of a special construction, do not need the pump of blowing just can realize the action of blowing. The specific structure of the air blowing assembly is as follows:

the air blowing assembly 4 comprises a rubber air blowing nozzle 40 and a driving mechanism 41, the rubber air blowing nozzle 40 is installed on the driving mechanism 41, the driving mechanism 41 can drive the rubber air blowing nozzle 40 to move towards the turntable assembly, and under the action of the driving mechanism, the rubber air blowing nozzle 40 collides against the turntable assembly 3 to deform and compress air to blow into the capillary 9 so as to blow away residues in the capillary 9. The key point is that the rubber blowing nozzle is impacted on the incubation turntable of the turntable assembly to cause compression deformation of the rubber blowing nozzle, so that the air is extruded and blown into the capillary. Therefore, an air blowing pump is not needed, the air blowing equipment is simplified, and the volume of the whole equipment can be reduced.

The utility model provides a concrete structure of this actuating mechanism:

actuating mechanism 41 includes electromagnet frame 410, electromagnet core 411 and electromagnet frame 412, electromagnet core 411 is installed in electromagnet frame 412, electromagnet frame 412 is fixed on electromagnet frame 410, electromagnet frame 410 is fixed on bottom plate 8, electromagnet frame 412 can be stretched out to electromagnet core 411 one end, rubber blowing nozzle 40 is fixed in the one end that electromagnet core 411 stretches out electromagnet frame 412, the electromagnet core circular telegram back, electromagnet core produces magnetism, the incubation carousel is the iron material, electromagnet core drives rubber blowing nozzle striking on the incubation carousel under the effect of magnetic force, compressed gas blows off the interior residual liquid of capillary. In order to realize the reset of the electromagnetic iron core, a reset spring is sleeved on the electromagnetic iron core, and the reset spring drives the electromagnetic iron core to reset after the electromagnetic iron core is powered off.

The sample assembly is used for providing a blood sample, and the centrifuged blood sample is sent to the capillary tube. The concrete structure of sample subassembly does:

the sample assembly 5 comprises a sample turntable 50, a bracket 51 and a sample motor 52, wherein the sample motor 52 is mounted on the bracket 51, the sample turntable 50 is mounted on an output shaft of the sample motor 52, the sample motor 52 drives the sample turntable 50 to rotate, and a plurality of sample cup bearing positions 501 are arranged on the sample turntable 50. The centrifuged blood sample is filled in the sample cup bearing position, the sample turntable rotates to rotate the sample cup bearing position filled with the sample to the turntable assembly, so that the sample cup bearing position is opposite to the capillary on the turntable assembly, and the capillary sucks the blood sample in the sample cup bearing position into the capillary through the siphoning effect.

To facilitate adjustment of the spacing between the sample assembly and the carousel assembly so that the capillary can siphon into the blood sample.

The sample assembly 5 further comprises a support moving mechanism 53, the support moving mechanism comprises a support motor 531 and a support rail 532, a support gear 533 is sleeved on an output shaft of the support motor 531, a support rack 534 is installed on the support 51, the support 51 is installed on the support rail 532, the support motor 531 rotates to drive the support gear to rotate, and the support gear rotates to drive the support to slide on the support rail.

In order to accurately position the capillary and the sample cup bearing position body, a position sensor can be arranged on the left side of the incubation rotating disc, the position sensor is required to rotate to the position of the capillary corresponding to the sample cup bearing position body, the sample rotating disc is driven to rotate only after the position sensor detects the capillary, and the sample cup bearing position body containing the sample is rotated to the position of the capillary so as to be adsorbed by the capillary. As can be seen in the figure, at the location of capillary siphoning of the sample, the sample cup carrying location body is inclined downwards, enabling the sample to drip out for capillary siphoning. This greatly simplifies the sampling mechanism.

The reagent assembly functions to supply various reagents such as washing solutions, antibodies, reactants, luminescent substrates, etc. to the capillary. The reagent assembly has the advantages that a plurality of reagent droplets can be provided, and the corresponding reagent droplets can be automatically extruded by using the reagent droplets.

The utility model discloses a reagent subassembly 6 includes reagent cup 60, reagent cup carousel 61 and reagent extrusion mechanism 62, reagent cup 60 internal partitioning becomes a plurality of reagent chambeies 63, be provided with a plurality of reagent outlet pipe 64 on the outside circumference of reagent cup 60, a reagent chamber 63 disposes a reagent outlet pipe 64, reagent outlet pipe and reagent chamber intercommunication, reagent cup carousel 61 is connected on reagent cup 60, install rubber membrane 615 in their junction, seal reagent chamber 63 through rubber membrane, avoid reagent chamber 63 outflow reagent, be provided with a plurality of through-holes and a transmission groove on the reagent carousel 61, the quantity of through-hole is the same with the reagent chamber, every through-hole communicates with a reagent chamber respectively, the transmission groove cup joints on the output shaft of motor 65, motor 65 drives reagent cup carousel 61 and rotates, reagent extrusion mechanism 62 includes pressure ram 66 and power supply 67, pressure ram 66 and power supply 67 (motor 65, motor pressure pump 67), Cylinder, oil cylinder, electric push rod, etc.) and under the action of the power source, the extrusion rod extends into the extrusion rubber membrane 615 from the through hole, and the rubber membrane deforms and extrudes the reagent in the reagent cavity, so that the reagent is extruded from the reagent outlet pipe. The extrusion rod is pushed to extrude the deformed rubber membrane, and the reagent in the reagent cavity is extruded out by the deformation of the rubber membrane. Because a plurality of reagent cavities are arranged in the reagent cup, one reagent is stored in each reagent cavity, when the reagent needs to be extruded, the rotating motor rotates, the reagent cavity with the reagent is aligned to the extrusion rod, and then the extrusion rod acts to extrude the reagent. In order to accurately position whether the required reagent chamber is aligned with the extrusion rod, a sensor can be arranged at the extrusion rod to detect whether the reagent chamber is aligned with the extrusion rod.

In order to adjust the distance between the reagent assembly and the turntable assembly and to siphon the reagent in a capillary tube, the reagent assembly further comprises a reagent mounting seat 68, a reagent line rail 69 and a reagent motor 610, a reagent gear 611 is sleeved on an output shaft of the reagent motor 610, a reagent rack 612 is mounted on the reagent mounting seat 68, the reagent gear 611 is meshed with the reagent rack 612, and the reagent mounting seat 68 is mounted on the reagent line rail 69 and slides on the reagent line rail under the action of the reagent motor. The reagent turntable, the rotating motor and the power source are all installed on the reagent installation seat, and thus the reagent cup, the reagent turntable, the rotating motor and the power source slide on the reagent line rail along with the reagent installation seat. The distance between the reagent assembly and the turntable assembly is integrally adjusted, and the capillary tube is ensured to siphon the reagent into the capillary tube.

In order to detect the size of the reagent droplets, a reagent droplet size detection sensor 614 (detection optocoupler) is arranged below the reagent cup, the detected size information of the reagent droplets is fed back to a controller of a power source, then the power source controls the action of an extrusion rod, and the extrusion rod does not extrude the reagent droplets with proper sizes.

The reagent cups 60 are clamped on the reagent cup rotating disc 61 through the reagent cup shell 613, clamping protrusions are arranged on the reagent cup shell, clamping grooves are arranged on the reagent cup rotating disc, after the clamping protrusions are embedded into the clamping grooves, the reagent cup shell is axially and radially fixed, and the reagent cups are sleeved on the reagent cup shell.

In order to ensure that the incubation rotating disc can accurately and accurately convey the capillary to the reagent position, a position sensor is arranged at the reagent position and used for detecting whether the capillary reaches the position or not, so that extruded reagent liquid drops can be siphoned by the capillary, and the waste of the reagent liquid drops caused by the fact that the capillary does not reach the position due to the extrusion of the reagent liquid drops is avoided.

The detection assembly 7 is used for detecting the capillary, and two processes are realized, namely, the capillary is pushed out from an incubation turntable of the turntable assembly, the pushed capillary is sent into a photoelectric detector for detection, and the capillary is released after the detection is finished, so that the detection of the next capillary is prepared.

The detection assembly 7 comprises a tube pushing mechanism 70, a photoelectric detector 71 and a tube supporting mechanism 72, the tube pushing mechanism 70 is installed on the left side of the rotary disc assembly 3 and used for pushing the capillary tube on the rotary disc assembly 3 out of the tube supporting mechanism 72, the tube supporting mechanism 72 is located at a detection port of the photoelectric detector 71, the tube supporting mechanism 7 sends the capillary tube to the photoelectric detector for detection, and after detection is finished, the capillary tube is lifted out of the photoelectric detector and released.

The pipe supporting mechanism 72 comprises a bracket I721, a bracket II 722, a bracket I driving mechanism and an impact plate 723, the bracket II 722 penetrates through the movable bracket I721, the bracket I driving mechanism comprises a bracket motor 724 and a bracket linear rail 725, the bracket I721 is installed on the bracket linear rail 725, a bracket gear 726 is installed on an output shaft of the bracket motor 724, a bracket rack 727 is installed on the bracket I721, the bracket gear 726 is meshed with the bracket rack 727, the bracket motor rotates to drive the bracket gear to rotate, the bracket rack is driven by the bracket gear to move so as to push the bracket I to move on the bracket linear rail, the bracket I721 is provided with a pipe supporting part, the bracket II 722 is provided with a pipe supporting part and a spring part, the spring part is provided with a spring 728, the other end of the spring 728 abuts against the bracket I721, under the action force of the spring, the pipe supporting part of the bracket I and the bracket II supporting pipe supporting part are, the impact plate 723 is mounted on the front side of the bracket II 722, and the bracket II can impact on the impact plate under the action of the bracket motor.

The tube supporting mechanism further comprises a capillary tube collecting box 7210, the capillary tube collecting box is located below the bracket I and the bracket II, and the impact plate is installed on the capillary tube collecting box.

Claims

1. A full-automatic chemiluminescence immunoassay device is characterized in that: including capillary storage module, capillary release subassembly, carousel subassembly, the subassembly of blowing, sample subassembly, reagent subassembly and determine module, the subassembly is located the left side of capillary storage module in the capillary, the carousel subassembly is located the right side of capillary storage module, the subassembly of blowing is located the left side of carousel subassembly, sample subassembly, reagent subassembly and determine module all are located the right side of carousel subassembly, the reagent subassembly is located the centre of sample subassembly and determine module, and capillary release subassembly will be located the capillary in capillary storage module and release, send the carousel subassembly to, the carousel subassembly rotates and carries sample subassembly, the subassembly of blowing, reagent subassembly and determine module position department with the capillary, the subassembly of blowing is used for cleaing away the remaining liquid in the capillary, the sample subassembly is used for providing the blood sample for the capillary, the reagent assembly is used for providing reagents for the capillary tube, and the detection assembly is used for detecting the number of photons emitted by the capillary tube.

2. The full-automatic chemiluminescence immunoassay device according to claim 1, wherein: the carousel subassembly includes incubation carousel and rotation motor, and the incubation carousel dress is provided with a plurality of capillary bearing holes on rotating the motor on the incubation carousel, and the incubation carousel includes disk body, heat preservation cotton and electrical heating membrane, and the electrical heating membrane is around on the disk body, and the cotton winding of heat preservation is on the electrical heating membrane.

3. The full-automatic chemiluminescence immunoassay device according to claim 1, wherein: the blowing assembly comprises a rubber blowing nozzle and a driving mechanism, the rubber blowing nozzle is installed on the driving mechanism, and the driving mechanism can drive the rubber blowing nozzle to move towards the turntable assembly.

4. The apparatus of claim 3, wherein the apparatus comprises: actuating mechanism includes electromagnetism iron frame, electromagnetic core and electromagnet frame, and electromagnetic core installs in the electromagnet frame, and the electromagnet frame is fixed on the electromagnetism iron frame, and the electromagnet frame can be stretched out to electromagnetic core one end, and the rubber blowing nozzle is fixed in the one end that the electromagnet frame stretched out the electromagnet frame at electromagnetic core.

5. The full-automatic chemiluminescence immunoassay device according to claim 1, wherein: the sample assembly comprises a sample turntable, a support and a sample motor, the sample motor is mounted on the support, the sample turntable is mounted on an output shaft of the sample motor, and a plurality of sample cup bearing positions are arranged on the sample turntable.

6. The apparatus of claim 5, wherein the apparatus comprises: the sample assembly further comprises a support moving mechanism, the support moving mechanism comprises a support motor and a support rail, a support gear is sleeved on an output shaft of the support motor, a support rack is arranged on the support, the support is arranged on the support rail, the support motor rotates to drive the support gear to rotate, and the support gear rotates to drive the support to slide on the support rail.

7. The full-automatic chemiluminescence immunoassay device according to claim 1, wherein: the reagent assembly comprises a reagent cup, a reagent cup turntable and a reagent extrusion mechanism, the interior of the reagent cup is divided into a plurality of reagent cavities, a plurality of reagent outlet pipes are arranged on the outer circumference of the reagent cup, one reagent cavity is provided with one reagent outlet pipe, the reagent outlet pipes are communicated with the reagent cavities, the reagent cup turntable is connected on the reagent cup, a rubber film is arranged at the joint of the reagent cup and the reagent cup turntable, the reagent cavities are connected with the rubber film, the reagent turntable is provided with a plurality of through holes and a transmission groove, the number of the through holes is the same as that of the reagent cavities, each through hole is respectively communicated with one reagent cavity, the transmission groove is sleeved on an output shaft of a motor, the reagent extrusion mechanism comprises an extrusion rod and a power source, the extrusion rod is connected with the power source, under the effect of power supply, the extrusion stem stretches into from the through-hole and contacts with the rubber membrane, extrudes reagent from the reagent outlet pipe through the reagent of extrusion rubber membrane extrusion reagent intracavity.

8. The apparatus of claim 7, wherein the apparatus comprises: the reagent assembly further comprises a reagent mounting seat, a reagent line rail and a reagent motor, a reagent gear is sleeved on an output shaft of the reagent motor, a reagent rack is mounted on the reagent mounting seat, the reagent gear is meshed with the reagent rack, and the reagent mounting seat is mounted on the reagent line rail.

9. The full-automatic chemiluminescence immunoassay device according to claim 1, wherein: the detection assembly comprises a tube pushing mechanism, a photoelectric detector and a tube supporting mechanism, the tube pushing mechanism is installed on the left side of the rotary disc assembly and used for pushing the capillary tube on the rotary disc assembly out of the tube supporting mechanism, the tube supporting mechanism is located at a detection port of the photoelectric detector and used for conveying the capillary tube into the photoelectric detector for detection, and after detection is finished, the capillary tube is lifted out of the photoelectric detector and released.

10. The apparatus of claim 9, wherein the apparatus comprises: the pipe supporting mechanism comprises a bracket I, a bracket II, a bracket I driving mechanism and an impact plate, the bracket II penetrates through a movable bracket I, the bracket I driving mechanism comprises a bracket motor and a bracket linear rail, the bracket I is installed on the bracket linear rail, a bracket gear is installed on an output shaft of the bracket motor, a bracket rack is installed on the bracket I, the bracket gear is meshed with the bracket rack, the bracket I is provided with a pipe supporting part, the bracket II is provided with a pipe supporting part and a spring part, the spring part is provided with a spring, the other end of the spring is abutted against the bracket I, under the action force of the spring, the pipe supporting part of the bracket I and the pipe supporting part of the bracket II are combined and attached together to form a V-shaped groove, the impact plate is installed on the front side of the bracket II, and the bracket II can impact.