CN210534171U - Full-automatic detection device for chemiluminescence immunoassay - Google Patents
Full-automatic detection device for chemiluminescence immunoassay Download PDFInfo
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- CN210534171U CN210534171U CN201921361513.XU CN201921361513U CN210534171U CN 210534171 U CN210534171 U CN 210534171U CN 201921361513 U CN201921361513 U CN 201921361513U CN 210534171 U CN210534171 U CN 210534171U
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- 238000001514 detection method Methods 0.000 title claims abstract description 43
- 238000003018 immunoassay Methods 0.000 title claims abstract description 22
- 230000007246 mechanism Effects 0.000 claims abstract description 60
- 230000009471 action Effects 0.000 claims description 11
- 238000002038 chemiluminescence detection Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 description 10
- 238000007664 blowing Methods 0.000 description 9
- 238000000034 method Methods 0.000 description 8
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- 108090000790 Enzymes Proteins 0.000 description 2
- 239000012491 analyte Substances 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
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- 108091007433 antigens Proteins 0.000 description 1
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- 238000012742 biochemical analysis Methods 0.000 description 1
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- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
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Abstract
The utility model discloses a full-automatic chemiluminescence detection device for immunoassay, including ejector sleeve mechanism, photoelectric detector and trusteeship mechanism, on ejector sleeve mechanism pushed away trusteeship mechanism with the capillary, trusteeship mechanism was located photoelectric detector's detection mouth department, and trusteeship mechanism detects in sending photoelectric detector with the capillary, has detected the back, holds in the palm out photoelectric detector with the capillary, releases the capillary. The utility model discloses automatically, send into the capillary and detect in the photoelectric detection appearance, detect and see off automatically again after accomplishing, can use on full-automatic chemiluminescence immunoassay device.
Description
Technical Field
The utility model relates to a biochemical analysis device especially relates to an utilize chemiluminescence method to carry out immunoassay's instrument.
Background
ChemiLuminescence (CL) is a type of molecular luminescence spectroscopy, and is a trace analysis method for determining the content of an analyte by detecting the ChemiLuminescence intensity of a system by using an instrument according to the principle that the concentration of the analyte in a chemical detection system and the ChemiLuminescence intensity of the system are in a linear quantitative relationship under a certain condition. The chemiluminescence method has wide application in the fields of trace metal ions, various inorganic compounds, organic compound analysis and biology.
Chemiluminescence immunoassay (CLIA) is a technique for detecting and analyzing various antigens, antibodies, hormones, enzymes, vitamins, drugs and the like by combining a chemiluminescence assay technique with high sensitivity and a high-specificity immunoreaction. Is an immunoassay technology developed after radioimmunoassay, enzyme immunoassay, fluoroimmunoassay and time-resolved fluoroimmunoassay. The chemiluminescence method has the advantages of high sensitivity, strong specificity, high accuracy, wide detection range and the like. Compared with the semi-quantitative enzyme-linked immunosorbent assay, the chemiluminescence assay is real quantitative, and the detection speed is higher and more convenient. Meanwhile, the chemiluminescent marker is stable, the effective period of the reagent is long, and the requirement of clinical application is greatly facilitated.
When the chemiluminescence immunoassay is carried out, substances such as a luminescent substrate and the like are added after the capillary tube reacts with a blood sample and then are required to be sent into a photoelectric detector for detection, the capillary tube is directly and manually sent into the photoelectric detector in the conventional mode, the mode requires manual participation, the automation degree is low, and the chemiluminescence immunoassay device cannot be applied to a full-automatic chemiluminescence immunoassay device.
SUMMERY OF THE UTILITY MODEL
In order to overcome the above-mentioned defect that current detection device detects the capillary and exists, the utility model provides a detection device for full-automatic chemiluminescence immunoassay, this detection device detects in sending into photoelectric detection appearance with the capillary automatically, and automatic the seeing off again after detecting the completion can use on full-automatic chemiluminescence immunoassay device.
In order to solve the technical problem, the utility model discloses the technical scheme who adopts is:
a detection device for full-automatic chemiluminescence immunoassay is characterized in that: the capillary tube pushing mechanism pushes the capillary tube to the tube supporting mechanism, the tube supporting mechanism is located at a detection port of the photoelectric detector, the tube supporting mechanism sends the capillary tube to the photoelectric detector for detection, and after detection is finished, the capillary tube is supported out of the photoelectric detector and the capillary tube is released.
The push pipe mechanism comprises a positioning assembly and a push pipe assembly, the positioning assembly comprises a positioning rail, a positioning motor, a positioning base and a positioning head, the positioning base is installed on the positioning rail, a positioning gear is sleeved on an output shaft of the positioning motor, a positioning rack is installed on the positioning base, the positioning gear is meshed with the positioning rack, the positioning head is installed on the positioning base, the push pipe assembly comprises a push pipe rail, a push pipe motor, a push pipe base and a push pipe rod, the push pipe base is installed on the push pipe rail, a push pipe gear is sleeved on an output shaft of the push pipe motor, the push pipe base is provided with the push pipe rack, the push pipe gear is meshed with the push pipe rack, the push pipe rod is installed on the push pipe base, the push pipe rod passes through the positioning base and the positioning head, and the push pipe rod can extend out of the positioning head.
The pipe supporting mechanism comprises a bracket I, a bracket II, a bracket I driving mechanism and an impact plate, the bracket II penetrates through a movable bracket I, the bracket I driving mechanism comprises a bracket motor and a bracket linear rail, the bracket I is installed on the bracket linear rail, a bracket gear is installed on an output shaft of the bracket motor, a bracket rack is installed on the bracket I, the bracket gear is meshed with the bracket rack, the bracket motor rotates to drive the bracket gear to rotate, the bracket gear rotates to drive the bracket rack to move, so that the bracket I is pushed to move on the bracket linear rail, the bracket I is provided with a bracket pipe part, the bracket II is provided with a bracket pipe part and a spring part, the spring part is provided with a spring, the other end of the spring is abutted against the bracket I, under the action force of the spring, the pipe supporting part of the bracket I and the pipe supporting part of the bracket II are abutted together to form a V-shaped groove, the, the bracket II can impact on the impact plate.
The capillary tube is pushed into a V-shaped groove formed by a bracket I and a bracket II by a tube pushing mechanism, then a bracket motor rotates to send the capillary tube into a photoelectric detector for detection, after the detection is finished, the bracket motor rotates to send the capillary tube out of the photoelectric detector and then continuously rotates until the bracket II impacts on an impact plate, the bracket motor stops rotating, the bracket II can move towards the photoelectric detector under the action of impact force, the bracket I does not move, at the moment, the bracket I is separated from the bracket II, the V-shaped groove is separated, the capillary tube falls from the V-shaped groove, then the bracket motor rotates reversely, the bracket I moves towards the photoelectric detector and leaves the impact plate, under the action force of a spring, the bracket II returns to the original position to form the V-shaped groove, the bracket motor continuously rotates until the bracket I returns to the original position to stop rotating, and the next capillary tube.
The tube supporting mechanism further comprises a capillary tube collecting box, the capillary tube collecting box is located below the bracket I and the bracket II, and the impact plate is installed in the capillary tube collecting box.
Compared with the prior art, the utility model discloses following beneficial effect has:
1. the utility model discloses detection device includes ejector sleeve mechanism, photoelectric detector and trusteeship mechanism, and on the ejector sleeve mechanism will change the capillary and release trusteeship mechanism, trusteeship mechanism was located photoelectric detector's detection mouth department, and trusteeship mechanism detects in sending the photoelectric detector with the capillary, has detected the back, holds in the palm out photoelectric detector with the capillary, and the capillary is fallen in the release. The feeding, the sending and the releasing actions of the capillary can be realized through the action of the detection device, and the full-automatic operation is realized. Does not need manual participation, improves the efficiency and can be applied to a full-automatic chemiluminescence immunoassay device.
2. The utility model discloses push tube mechanism includes locating component and ejector sleeve subassembly, locating component includes location rail, positioning motor, location frame and location head, and the location frame is installed on the location rail, has cup jointed the location gear on positioning motor's the output shaft, installs the location rack on the location frame, location gear and location rack toothing, and the location head is installed on the frame of location, the ejector sleeve subassembly includes push tube rail, push tube motor, push tube frame and push tube pole, and the push tube frame is installed on the push tube rail, has cup jointed the push tube gear on the output shaft of push tube motor, installs the push tube rack on the push tube frame, push tube gear and push tube rack toothing, and the push tube pole is installed on the push tube frame, and location frame and location head are crossed to the push tube pole, and the location head can be stretched out to the push tube pole. The pipe pushing mechanism is matched with the rotary disc assembly, the rotary disc assembly is located through the locating head, then the capillary is pushed out to the pipe supporting mechanism through the pipe pushing rod, firstly, the rotary disc assembly can be located, and the capillary can be accurately pushed to the pipe supporting mechanism through the pipe pushing rod. Meanwhile, the positioning head can also avoid the pipe pushing rod from deforming under stress.
3. The utility model discloses a trusteeship mechanism includes bracket I, bracket II, bracket I actuating mechanism and striking plate, and bracket II passes and moves bracket I, and bracket I actuating mechanism includes bracket motor and bracket linear rail, and bracket I installs on bracket linear rail, installs the bracket gear on the output shaft of bracket motor, installs the bracket rack on bracket I, and bracket gear meshes with the bracket rack, and bracket motor rotates and drives bracket gear rotation, and bracket gear rotation drive bracket rack motion to promote bracket I to move on bracket linear rail, bracket I is provided with trusteeship portion, bracket II is provided with trusteeship portion and spring portion, the spring portion is installed with the spring, and the other end of spring supports and leans on bracket I, and under the effort of spring, bracket I's trusteeship portion and bracket II trusteeship portion close together and form the V-arrangement groove, and striking plate installs the front side at bracket II, under the action of the bracket motor, the bracket II can impact on the impact plate. Through the structure of the tube supporting mechanism, the tube supporting mechanism can automatically send the capillary tube into and out of the photoelectric detector, and the detected capillary tube can be released through the action of the impact plate so that the next capillary tube can enter.
Drawings
FIG. 1 is a schematic structural view of the pipe pushing-free mechanism of the present invention;
FIG. 2 is the schematic diagram of the structure of the tube supporting mechanism of the present invention
FIG. 3 is a schematic structural view of a bracket II of the present invention;
FIG. 4 is a schematic view of the installation position of the device without a pipe pushing mechanism according to the present invention;
FIG. 5 is a schematic view of the installation position of the pipe pushing mechanism of the present invention;
FIG. 6 is a schematic structural view of the tube pushing mechanism of the present invention;
FIG. 7 is a schematic view of another view line structure of the tube pushing mechanism of the present invention;
fig. 8 is a schematic structural view of the full-automatic chemiluminescence immunoassay device assembled with other components according to the present invention.
Reference numeral 1, a capillary tube storage component, 2, a capillary tube pushing component, 3, a turntable component, 4, a blowing component, 5, a sample component, 6, a reagent component, 7, a detection device, 70, a tube pushing mechanism, 701, a positioning rail, 702, a positioning motor, 703, a positioning base, 704, a positioning head, 705, a positioning gear, 706, a positioning rack, 707, a tube pushing rail, 708, a tube pushing motor, 709, a tube pushing base, 7010, a tube pushing rod, 7011, a tube pushing gear, 7012, a tube pushing rack, 71, a photoelectric detector, 72, a tube supporting mechanism, 721, a bracket I, 722, a bracket II, 723, a striking plate, 724, a bracket motor, 725, a bracket wire rail, 726, a bracket gear, 727, a bracket rack, 728, a spring, 729, a V-shaped groove, 7210, a capillary tube collecting box, 8, a bottom plate, 9 and a capillary tube.
Detailed Description
The present invention will be further described with reference to the following examples, which are only some, but not all, of the examples of the present invention. Based on the embodiments in the present invention, other embodiments used by those skilled in the art without creative work belong to the protection scope of the present invention. The utility model discloses the position word that appears in like "preceding", "back", "left", "right", has only represented relative position relation, all is the description of going on to the position of figure 8 to the position around not necessarily being actual, consequently can not do the restrictive understanding.
The utility model provides a detection device 7 is used for detecting the capillary, and it will realize two processes, firstly releases the capillary from turntable assembly's turntable assembly, but detects in sending into photoelectric detection appearance with the capillary that releases, still will release the capillary after having detected, makes ready work for next capillary detects.
The detection device 7 comprises a tube pushing mechanism 70, a photoelectric detector 71 and a tube supporting mechanism 72, wherein the tube pushing mechanism 70 is installed on the left side of the rotary disc assembly 3 and used for pushing the capillary tube on the rotary disc assembly 3 out of the tube supporting mechanism 72, the tube supporting mechanism 72 is located at a detection port of the photoelectric detector 71, the tube supporting mechanism 7 is used for sending the capillary tube to the photoelectric detector for detection, and after detection is finished, the capillary tube is lifted out of the photoelectric detector and released.
The pipe pushing mechanism comprises a positioning component and a pipe pushing component, the positioning component comprises a positioning rail 701, a positioning motor 702, a positioning base 703 and a positioning head 704, the positioning base 703 is arranged on the positioning rail 701, a positioning gear 705 is sleeved on an output shaft of the positioning motor 702, a positioning rack 706 is arranged on the positioning base 703, the positioning gear 705 is meshed with the positioning rack 706, the positioning head 704 is arranged on the positioning base 703, the pipe pushing assembly comprises a pipe pushing rail 707, a pipe pushing motor 708, a pipe pushing base 709 and a pipe pushing rod 7010, the pipe pushing base 709 is mounted on the pipe pushing rail 707, a pipe pushing gear 7011 is sleeved on an output shaft of the pipe pushing motor 708, a pipe pushing rack 7012 is mounted on the pipe pushing base 709, the pipe pushing gear 7011 is meshed with the pipe pushing rack 7012, the pipe pushing rod 7010 is mounted on the pipe pushing base 709, the pipe pushing rod 7010 penetrates through the positioning base 703 and the positioning head 704, and the pipe pushing rod 7010 can extend out of the positioning head 704.
The pipe supporting mechanism 72 comprises a bracket I721, a bracket II 722, a bracket I driving mechanism and an impact plate 723, the bracket II 722 penetrates through the movable bracket I721, the bracket I driving mechanism comprises a bracket motor 724 and a bracket linear rail 725, the bracket I721 is installed on the bracket linear rail 725, a bracket gear 726 is installed on an output shaft of the bracket motor 724, a bracket rack 727 is installed on the bracket I721, the bracket gear 726 is meshed with the bracket rack 727, the bracket motor rotates to drive the bracket gear to rotate, the bracket rack is driven by the bracket gear to move so as to push the bracket I to move on the bracket linear rail, the bracket I721 is provided with a pipe supporting part, the bracket II 722 is provided with a pipe supporting part and a spring part, the spring part is provided with a spring 728, the other end of the spring 728 abuts against the bracket I721, under the action force of the spring, the pipe supporting part of the bracket I and the bracket II supporting pipe supporting part are, the impact plate 723 is mounted on the front side of the bracket II 722, and the bracket II can impact on the impact plate under the action of the bracket motor.
The capillary tube is pushed into a V-shaped groove formed by a bracket I and a bracket II by a tube pushing mechanism, then a bracket motor rotates to send the capillary tube into a photoelectric detector for detection, after the detection is finished, the bracket motor rotates to send the capillary tube out of the photoelectric detector and then continuously rotates until the bracket II impacts on an impact plate, the bracket motor stops rotating, the bracket II can move towards the photoelectric detector under the action of impact force, the bracket I does not move, at the moment, the bracket I is separated from the bracket II, the V-shaped groove is separated, the capillary tube falls from the V-shaped groove, then the bracket motor rotates reversely, the bracket I moves towards the photoelectric detector and leaves the impact plate, under the action force of a spring, the bracket II returns to the original position to form the V-shaped groove, the bracket motor continuously rotates until the bracket I returns to the original position to stop rotating, and the next capillary tube.
The tube supporting mechanism further comprises a capillary tube collecting box 7210, the capillary tube collecting box is located below the bracket I and the bracket II, and the impact plate is installed on the capillary tube collecting box 7210.
The utility model provides a full-automatic chemiluminescence immunoassay device, the device's effect is all steps of realizing blood sample chemiluminescence immunoassay, and whole automation mechanized operation, the user only need load the blood sample, and the starting equipment can carry out full automated inspection, the automated generation testing result. The device has the following specific structure:
the method comprises the following steps: capillary storage component 1, capillary push-out component 2, carousel component 3, gas blowing component 4, sample subassembly 5, reagent subassembly 6, detection device 7 and bottom plate 8, above-mentioned subassembly is all installed on bottom plate 8. Their relative positional relationship is: capillary release subassembly 2 is located the left side of capillary storage subassembly 1, carousel subassembly 3 is located the right side of capillary storage subassembly 1, blowing subassembly 4 is located carousel subassembly 3's left side, and blowing subassembly 4 is located capillary storage subassembly 1 and capillary release subassembly 2's front side, and capillary storage subassembly 1 and capillary release subassembly 2 pass through the mounting panel and install in the left side of 3 side parts on carousel subassembly, and the left side in carousel subassembly 3 the latter half is installed to blowing subassembly 4. The sample assembly 5, reagent assembly 6 and detection device 7 are all located on the right side of the turntable assembly 3, the reagent assembly 6 is located in the middle of the sample assembly 5 and detection device 7, the sample assembly 5 is located on the front right side of the turntable assembly, and the detection device is located on the rear right side of the turntable assembly. And a waste liquid groove is arranged below the sample assembly, the air blowing assembly and the reagent assembly, the waste liquid groove is arranged below the bottom plate, and the waste liquid groove is used for collecting waste liquid generated by the sample assembly, the air blowing assembly and the reagent assembly.
The capillary tube pushing assembly 2 pushes out the capillary tube in the capillary tube storage assembly 1 and sends the capillary tube to the turntable assembly 3, the turntable assembly 3 rotates to convey the capillary tube 9 to the positions of the sample assembly 5, the blowing assembly 4, the reagent assembly 6 and the detection device 7, the blowing assembly is used for removing residual liquid in the capillary tube 9, the sample assembly is used for providing a blood sample for the capillary tube, the reagent assembly is used for providing a reagent for the capillary tube, and the detection device is used for detecting the number of photons emitted by the capillary tube.
Claims (4)
1. A detection device for full-automatic chemiluminescence immunoassay is characterized in that: the capillary tube pushing mechanism pushes the capillary tube to the tube supporting mechanism, the tube supporting mechanism is located at a detection port of the photoelectric detector, the tube supporting mechanism sends the capillary tube to the photoelectric detector for detection, and after detection is finished, the capillary tube is supported out of the photoelectric detector and released.
2. The detection device for full-automatic chemiluminescence immunoassay according to claim 1, wherein: the push pipe mechanism comprises a positioning assembly and a push pipe assembly, the positioning assembly comprises a positioning rail, a positioning motor, a positioning base and a positioning head, the positioning base is installed on the positioning rail, a positioning gear is sleeved on an output shaft of the positioning motor, a positioning rack is installed on the positioning base, the positioning gear is meshed with the positioning rack, the positioning head is installed on the positioning base, the push pipe assembly comprises a push pipe rail, a push pipe motor, a push pipe base and a push pipe rod, the push pipe base is installed on the push pipe rail, a push pipe gear is sleeved on an output shaft of the push pipe motor, the push pipe base is provided with the push pipe rack, the push pipe gear is meshed with the push pipe rack, the push pipe rod is installed on the push pipe base, the push pipe rod passes through the positioning base and the positioning head, and the push pipe rod can extend out of the positioning head.
3. The detection device for full-automatic chemiluminescence immunoassay according to claim 1, wherein: the pipe supporting mechanism comprises a bracket I, a bracket II, a bracket I driving mechanism and an impact plate, the bracket II penetrates through a movable bracket I, the bracket I driving mechanism comprises a bracket motor and a bracket linear rail, the bracket I is installed on the bracket linear rail, a bracket gear is installed on an output shaft of the bracket motor, a bracket rack is installed on the bracket I, the bracket gear is meshed with the bracket rack, the bracket I is provided with a pipe supporting part, the bracket II is provided with a pipe supporting part and a spring part, the spring part is provided with a spring, the other end of the spring is abutted against the bracket I, under the action force of the spring, the pipe supporting part of the bracket I and the pipe supporting part of the bracket II are combined and attached together to form a V-shaped groove, the impact plate is installed on the front side of the bracket II, and the bracket II can impact.
4. The detection device for full-automatic chemiluminescence immunoassay according to claim 1, wherein: the tube supporting mechanism further comprises a capillary tube collecting box, the capillary tube collecting box is located below the bracket I and the bracket II, and the impact plate is installed on the capillary tube collecting box.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921361513.XU CN210534171U (en) | 2019-08-21 | 2019-08-21 | Full-automatic detection device for chemiluminescence immunoassay |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921361513.XU CN210534171U (en) | 2019-08-21 | 2019-08-21 | Full-automatic detection device for chemiluminescence immunoassay |
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| Publication Number | Publication Date |
|---|---|
| CN210534171U true CN210534171U (en) | 2020-05-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921361513.XU Active CN210534171U (en) | 2019-08-21 | 2019-08-21 | Full-automatic detection device for chemiluminescence immunoassay |
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| Country | Link |
|---|---|
| CN (1) | CN210534171U (en) |
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2019
- 2019-08-21 CN CN201921361513.XU patent/CN210534171U/en active Active
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Address after: No.1, 1st floor, building 1, No.333 Hezuo Road, high tech Zone, Chengdu, Sichuan 610000 Patentee after: Chengdu Smart Technology Co.,Ltd. Country or region after: China Address before: No.1, 1st floor, building 1, No.333 Hezuo Road, high tech Zone, Chengdu, Sichuan 610000 Patentee before: CHENGDU SEAMATY TECHNOLOGY Co.,Ltd. Country or region before: China |