CN211318474U - Full-automatic gas blowing device for chemiluminescence immunoassay - Google Patents
Full-automatic gas blowing device for chemiluminescence immunoassay Download PDFInfo
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- CN211318474U CN211318474U CN201921362130.4U CN201921362130U CN211318474U CN 211318474 U CN211318474 U CN 211318474U CN 201921362130 U CN201921362130 U CN 201921362130U CN 211318474 U CN211318474 U CN 211318474U
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Abstract
The utility model discloses a full automatization chemiluminescence gas blowing device for immunoassay, including rubber blowing nozzle and actuating mechanism, rubber blowing nozzle installs on actuating mechanism, actuating mechanism includes electromagnet frame, electromagnet core and electromagnet frame, and electromagnet core installs in the electromagnet frame, and the electromagnet frame is fixed on the electromagnet frame, and the electromagnet frame can be stretched out to electromagnet core one end, and rubber blowing nozzle fixes the one end that stretches out the electromagnet frame at electromagnet core. The utility model discloses do not need vacuum pump and pipeline isotructure, the structure is simplified, and is miniaturized, can reduce whole automatic chemiluminescence immunoassay device's volume, and manufacturing cost also can corresponding reduction moreover.
Description
Technical Field
The utility model relates to a biochemical analysis device especially relates to an utilize chemiluminescence method to carry out immunoassay's instrument.
Background
ChemiLuminescence (CL) is a type of molecular luminescence spectroscopy, and is a trace analysis method for determining the content of an analyte by detecting the ChemiLuminescence intensity of a system by using an instrument according to the principle that the concentration of the analyte in a chemical detection system and the ChemiLuminescence intensity of the system are in a linear quantitative relationship under a certain condition. The chemiluminescence method has wide application in the fields of trace metal ions, various inorganic compounds, organic compound analysis and biology.
Chemiluminescence immunoassay (CLIA) is a technique for detecting and analyzing various antigens, antibodies, hormones, enzymes, vitamins, drugs and the like by combining a chemiluminescence assay technique with high sensitivity and a high-specificity immunoreaction. Is an immunoassay technology developed after radioimmunoassay, enzyme immunoassay, fluoroimmunoassay and time-resolved fluoroimmunoassay. The chemiluminescence method has the advantages of high sensitivity, strong specificity, high accuracy, wide detection range and the like. Compared with the semi-quantitative enzyme-linked immunosorbent assay, the chemiluminescence assay is real quantitative, and the detection speed is higher and more convenient. Meanwhile, the chemiluminescent marker is stable, the effective period of the reagent is long, and the requirement of clinical application is greatly facilitated.
The chemiluminescence immunoassay using the capillary as a carrier mainly comprises the following steps: coating the capillary, centrifuging the blood sample, sucking the blood sample by the capillary, performing multiple capillary purges and sucking reagents, incubating and detecting. An air-blowing device is used to purge the capillary. If the utility model discloses a chinese utility model patent of authorizing bulletin number CN207964849U, the date of authorizing bulletin is 2018, 10 months 12 days discloses a chemiluminescence immunoassay appearance gas blowing device, including vacuum pump, pipeline, branch wind ware and air blow needle, the vacuum pump is connected to pipeline one end, and the inlet end of branch wind ware is connected to the other end, the end of giving vent to anger of branch wind ware is two, is connected with shunt tubes one and shunt tubes two respectively, a shunt tubes end-to-end connection air blow needle, the air blow route of air blow needle and the two terminal air blow route of shunt tubes are perpendicular and crossing, and the air blow needle end is greater than the length of waiting to blow the capillary apart from the two terminal air blow routes of shunt tubes. The device can thoroughly clear away the residual reagent in the capillary, effectively improves chemiluminescence immunoassay's accuracy. This gas blowing device's realization needs use the vacuum pump, still need use shunt tubes and various pipelines, and the structure is complicated, and is bulky, is used in full autoanalyzer, can cause whole analysis appearance bulky, and manufacturing cost is high.
SUMMERY OF THE UTILITY MODEL
In order to overcome the structure complicacy that above-mentioned gas blowing device exists, it is bulky, the higher defect of manufacturing cost, the utility model provides a full automatization chemiluminescence gas blowing device for immunoassay, this gas blowing device does not need vacuum pump and pipeline isotructure, and the structure is simplified, and is miniaturized, can reduce whole automatic chemiluminescence immunoassay device's volume, and manufacturing cost also can corresponding reduction moreover.
In order to solve the technical problem, the utility model discloses the technical scheme who adopts is:
the utility model provides a full-automatic chemiluminescence gas blowing device for immunoassay which characterized in that: comprises a rubber blowing nozzle and a driving mechanism, wherein the rubber blowing nozzle is arranged on the driving mechanism. The driving mechanism can drive the rubber blowing nozzle to move towards a turntable assembly of the full-automatic chemiluminescence immunoassay device, and under the action of the driving mechanism, the rubber blowing nozzle collides against the turntable assembly, deforms and compresses gas to be blown into the capillary tube, and blows away residues in the capillary tube.
The driving mechanism can be realized by an air cylinder, an oil cylinder or a structure combining a gear rack and a motor.
The utility model provides a concrete structure of this actuating mechanism:
actuating mechanism includes the electromagnetism iron frame, electromagnet core and electromagnet frame, electromagnet core installs in the electromagnet frame, the electromagnet frame is fixed on the electromagnet frame, the electromagnet frame can be stretched out to electromagnet core one end, the rubber blowing nozzle is fixed in the one end that electromagnet core stretches out the electromagnet frame, after the electromagnet core circular telegram, electromagnet core produces magnetism, the carousel subassembly is the iron material, electromagnet core drives the striking of rubber blowing nozzle on the carousel subassembly under the effect of magnetic force, compressed gas blows the remaining liquid in the capillary. In order to realize the reset of the electromagnetic iron core, a reset spring is sleeved on the electromagnetic iron core, and the reset spring drives the electromagnetic iron core to reset after the electromagnetic iron core is powered off.
In order to realize that the turntable assembly can drive the capillary tube to rotate to the position of the air blowing device, the air blowing device comprises a position sensor, the position sensor is arranged at the position of the rubber air blowing nozzle and used for detecting whether the capillary tube is arranged in the capillary tube bearing hole aligned to the rubber air blowing nozzle or not, and when the capillary tube is arranged, the electromagnet is connected with a power supply to enable the rubber air blowing nozzle to impact the turntable assembly. Certainly, the position sensor is not needed, and the rotation angle of the turntable is calculated only after the blowing device is installed, and the capillary tube can also be positioned.
Compared with the prior art, the utility model discloses following beneficial effect has:
1. the utility model discloses carried out great simplification to gas blowing device, gas blowing device only includes a rubber blowing nozzle and a actuating mechanism can realize blowing, does not need gas supply unit, also does not need the pipeline of air feed etc. the structure is simplified greatly, the gas of production can be clear away the remaining liquid in the capillary again, use on full-automatic chemiluminescence analysis appearance, not only can reduce whole volume together for the instrument is more miniaturized, but also can reduce whole manufacturing cost together, easily popularization and application.
2. The utility model discloses an actuating mechanism includes electromagnet frame, electromagnet core and electromagnet frame, comes controller actuating mechanism motion through the electro-magnet, with the striking of rubber blowing nozzle on the rotary assembly, lets the compression of rubber blowing nozzle, advances the capillary with gas compression in, actuating mechanism simple structure, it is small.
Drawings
FIG. 1 is a schematic view of the overall structure of the present invention;
fig. 2 is a schematic diagram of the structure of the present invention applied to a full-automatic luminescence immunoassay analyzer.
The capillary tube detection device comprises a reference numeral 1, a capillary tube storage component, 2, a capillary tube pushing component, 3, a turntable component, 4, a blowing device, 40, a rubber blowing nozzle, 41, a driving mechanism, 410, an electromagnet frame, 411, an electromagnet core, 412, an electromagnet frame, 5, a sample component, 6, a reagent component, 7, a detection component, 8, a bottom plate, 9 and a capillary tube.
Detailed Description
The present invention will be further described with reference to the following examples, which are only some, but not all, of the examples of the present invention. Based on the embodiments in the present invention, other embodiments used by those skilled in the art without creative work belong to the protection scope of the present invention. The utility model discloses the position word that appears in like "preceding", "back", "left", "right", has only represented relative position relation, all is the description of going on to the position of fig. 2 to the position around not necessarily being actual, consequently can not do the restrictive understanding.
The utility model provides a full-automatic chemiluminescence gas blowing device for immunoassay, gas blowing device's effect is the effect of realizing blowing, clears up remaining liquid in the capillary. The specific structure of the blowing device is as follows:
the air blowing device 4 comprises a rubber air blowing nozzle 40 and a driving mechanism 41, the air blowing nozzle 40 is installed on the driving mechanism 41, the driving mechanism 41 can drive the rubber air blowing nozzle 40 to move towards the turntable assembly, and under the action of the driving mechanism, the rubber air blowing nozzle 40 collides against the turntable assembly 3 to deform and compress air to blow into the capillary 9 so as to blow away residues in the capillary 9. The key point is that the rubber blowing nozzle is impacted on the turntable assembly to cause compression deformation of the rubber blowing nozzle, so that gas is extruded and blown into the capillary. Therefore, an air blowing pump is not needed, the air blowing equipment is simplified, and the volume of the whole equipment can be reduced.
The driving mechanism can be realized by an air cylinder, an oil cylinder or a structure combining a gear rack and a motor.
The utility model provides a concrete structure of this actuating mechanism:
In order to realize that the turntable assembly can drive the capillary tube to rotate to the position of the air blowing device, the air blowing device comprises a position sensor, the position sensor is arranged at the position of the rubber air blowing nozzle and used for detecting whether the capillary tube is arranged in the capillary tube bearing hole aligned to the rubber air blowing nozzle or not, and when the capillary tube is arranged, the electromagnet is connected with a power supply to enable the rubber air blowing nozzle to impact the turntable assembly. Certainly, the position sensor is not needed, and the rotation angle of the turntable is calculated only after the blowing device is installed, and the capillary tube can also be positioned.
The utility model also provides a full-automatic chemiluminescence immunoassay device, the device's effect is all steps of realizing blood sample chemiluminescence immunoassay, and whole automation mechanized operation, the user only need load the blood sample, and the starting equipment can carry out full automated inspection, the automated generation testing result. The device has the following specific structure:
the method comprises the following steps: capillary storage component 1, capillary push-out component 2, carousel component 3, gas blowing device 4, sample subassembly 5, reagent subassembly 6, determine module 7 and bottom plate 8, above-mentioned subassembly is all installed on bottom plate 8. Their relative positional relationship is: capillary release subassembly 2 is located the left side of capillary storage subassembly 1, carousel subassembly 3 is located the right side of capillary storage subassembly 1, gas blowing device 4 is located carousel subassembly 3's left side, and gas blowing device 4 is located capillary storage subassembly 1 and capillary release subassembly 2's front side, and capillary storage subassembly 1 and capillary release subassembly 2 pass through the mounting panel and install in the left side of 3 side parts on carousel subassembly, and gas blowing device 4 installs the left side in carousel subassembly 3 the latter half. Sample subassembly 5, reagent subassembly 6 and determine module 7 all are located the right side of carousel subassembly 3, reagent subassembly 6 is located the centre of sample subassembly 5 and determine module 7, and sample subassembly 5 is located the right front side of carousel subassembly, and determine module is located the back right side of carousel subassembly. And a waste liquid groove is arranged below the sample assembly, the air blowing device and the reagent assembly, the waste liquid groove is arranged below the bottom plate, and the waste liquid groove is used for collecting waste liquid generated by the sample assembly, the air blowing device and the reagent assembly.
The capillary tube pushing assembly 2 pushes out the capillary tube in the capillary tube storage assembly 1 and sends the capillary tube to the turntable assembly 3, the turntable assembly 3 rotates to convey the capillary tube 9 to the positions of the sample assembly 5, the blowing device 4, the reagent assembly 6 and the detection assembly 7, the blowing device is used for removing residual liquid in the capillary tube 9, the sample assembly is used for providing a blood sample for the capillary tube, the reagent assembly is used for providing a reagent for the capillary tube, and the detection assembly is used for detecting the number of photons emitted by the detection capillary tube.
Claims (3)
1. The utility model provides a full-automatic chemiluminescence gas blowing device for immunoassay which characterized in that: comprises a rubber blowing nozzle and a driving mechanism, wherein the rubber blowing nozzle is arranged on the driving mechanism; actuating mechanism includes electromagnetism iron frame, electromagnetic core and electromagnet frame, and electromagnetic core installs in the electromagnet frame, and the electromagnet frame is fixed on the electromagnetism iron frame, and the electromagnet frame can be stretched out to electromagnetic core one end, and the rubber blowing nozzle is fixed in the one end that the electromagnet frame stretched out the electromagnet frame at electromagnetic core.
2. The blowing device for full-automatic chemiluminescence immunoassay according to claim 1, wherein: and the electromagnetic iron core is sleeved with a return spring.
3. The blowing device for full-automatic chemiluminescence immunoassay according to claim 1, wherein: the air blowing device comprises a sensor, the sensor is arranged at the position of the rubber air blowing nozzle and is connected with a controller, and the controller is connected with the electromagnetic iron core.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921362130.4U CN211318474U (en) | 2019-08-21 | 2019-08-21 | Full-automatic gas blowing device for chemiluminescence immunoassay |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921362130.4U CN211318474U (en) | 2019-08-21 | 2019-08-21 | Full-automatic gas blowing device for chemiluminescence immunoassay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211318474U true CN211318474U (en) | 2020-08-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921362130.4U Active CN211318474U (en) | 2019-08-21 | 2019-08-21 | Full-automatic gas blowing device for chemiluminescence immunoassay |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN211318474U (en) |
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2019
- 2019-08-21 CN CN201921362130.4U patent/CN211318474U/en active Active
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