CN210294300U - Sample storage rotary disc for chemiluminescence immunoassay - Google Patents
Sample storage rotary disc for chemiluminescence immunoassay Download PDFInfo
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- CN210294300U CN210294300U CN201921208642.5U CN201921208642U CN210294300U CN 210294300 U CN210294300 U CN 210294300U CN 201921208642 U CN201921208642 U CN 201921208642U CN 210294300 U CN210294300 U CN 210294300U
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- 238000003018 immunoassay Methods 0.000 title claims abstract description 14
- 238000001514 detection method Methods 0.000 claims abstract description 30
- 238000005119 centrifugation Methods 0.000 claims abstract description 22
- 239000008280 blood Substances 0.000 claims description 13
- 210000004369 blood Anatomy 0.000 claims description 13
- 238000000151 deposition Methods 0.000 abstract 1
- 238000005070 sampling Methods 0.000 description 37
- 239000007788 liquid Substances 0.000 description 15
- 239000003153 chemical reaction reagent Substances 0.000 description 12
- 238000011534 incubation Methods 0.000 description 10
- 238000007664 blowing Methods 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 239000012491 analyte Substances 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 238000002965 ELISA Methods 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- -1 antibodies Substances 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000012742 biochemical analysis Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000036046 immunoreaction Effects 0.000 description 1
- 150000002484 inorganic compounds Chemical class 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 238000000504 luminescence detection Methods 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 238000003127 radioimmunoassay Methods 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 229910021655 trace metal ion Inorganic materials 0.000 description 1
- 238000004454 trace mineral analysis Methods 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
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Abstract
The utility model discloses a chemiluminescent immunoassay is with depositing appearance carousel, including slewing mechanism, disk body and detection sensor, slewing mechanism includes axis of rotation and motor, and axis of rotation and motor link to each other, and the motor drive axis of rotation rotates, the disk body cup joints in the axis of rotation, and the disk body rotates along with the axis of rotation, be provided with centrifugation cup slot and TF head groove on the disk body, centrifugation cup slot is used for placing the centrifugation cup, TF head groove is used for placing the TF head, the detection sensor is installed in the disk body below. The utility model discloses can obviously improve sample efficiency, easy operation is convenient, labour saving and time saving.
Description
Technical Field
The utility model relates to a biochemical analysis device especially relates to a deposit appearance device.
Background
ChemiLuminescence (CL) is a type of molecular luminescence spectroscopy, and is a trace analysis method for determining the content of an analyte by detecting the ChemiLuminescence intensity of a system by using an instrument according to the principle that the concentration of the analyte in a chemical detection system and the ChemiLuminescence intensity of the system are in a linear quantitative relationship under a certain condition. The chemiluminescence method has wide application in the fields of trace metal ions, various inorganic compounds, organic compound analysis and biology.
Chemiluminescence immunoassay (CLIA) is a technique for detecting and analyzing various antigens, antibodies, hormones, enzymes, vitamins, drugs and the like by combining a chemiluminescence assay technique with high sensitivity and a high-specificity immunoreaction. Is an immunoassay technology developed after radioimmunoassay, enzyme immunoassay, fluoroimmunoassay and time-resolved fluoroimmunoassay. The chemiluminescence method has the advantages of high sensitivity, strong specificity, high accuracy, wide detection range and the like. Compared with the semi-quantitative enzyme-linked immunosorbent assay, the chemiluminescence assay is real quantitative, and the detection speed is higher and more convenient. Meanwhile, the chemiluminescent marker is stable, the effective period of the reagent is long, and the requirement of clinical application is greatly facilitated.
When the chemiluminescence immunoassay is carried out, a blood sample after centrifugation is needed, and then the blood sample is added into a reaction carrier for reaction so as to carry out the chemiluminescence immunoassay. The conventional method is to store a blood sample by using a centrifugal cup, and the blood sample is manually sucked from the centrifugal cup when the blood sample is needed, the method needs a person to hang a TF head on a sucking device manually and then insert the TF head into the centrifugal cup to suck the blood sample, and the centrifugal cup and the TF head need to be picked up and fixed manually, so that the operation efficiency is obviously influenced.
SUMMERY OF THE UTILITY MODEL
In order to overcome the defects, the utility model provides a sample storage turntable does not need the manual work to pick up and fix centrifugal cup and TF head through this carousel, can obviously raise the efficiency, and easy operation is convenient.
In order to solve the technical problem, the utility model discloses the technical scheme who adopts is:
a sample storage rotary disk for chemiluminescence immunoassay is characterized in that: including slewing mechanism, disk body and detection sensor, slewing mechanism includes axis of rotation and motor, and axis of rotation and motor link to each other, and the motor drive axis of rotation rotate, the disk body cup joints in the axis of rotation, and the disk body rotates along with the axis of rotation, be provided with centrifugation cup groove and TF head groove on the disk body, centrifugation cup groove is used for placing the centrifugation cup, TF head groove is used for placing the TF head, detection sensor installs in the disk body below for whether there is the centrifugation cup in the centrifugation cup groove that detects to enter into this detection sensor department, whether there is the TF head in the TF head groove, through this detection sensor turned angle that the disk body just can be controlled to guarantee to rotate TF head and centrifugation cup to the sampling position, so that take a sample and move.
The centrifugal cup is internally provided with a blood sample after centrifugation, the centrifugal cup groove is provided with a centrifugal cup cover limiting groove, the centrifugal cup is placed in the centrifugal cup groove, and the centrifugal cup cover is opened and limited in the centrifugal cup cover groove.
Compared with the prior art, the utility model discloses following beneficial effect has:
the utility model discloses a rotation drive mechanism, disk body and detection sensor, slewing mechanism includes axis of rotation and motor, and axis of rotation and motor link to each other, and the motor drive axis of rotation rotates, the disk body cup joints in the axis of rotation, and the disk body rotates along with the axis of rotation, be provided with centrifugation cup groove and TF head groove on the disk body, centrifugation cup groove is used for placing the centrifugation cup, TF head groove is used for placing the TF head, detection sensor installs in the disk body below for whether there is the centrifugation cup in the centrifugation cup groove that detects to enter into this detection sensor department, whether there is the TF head in the TF head groove, just can control the turned angle of disk body through this detection sensor, in order to guarantee to rotate the below of sampling mechanism with TF head and centrifugation cup, so that take a sample and move. The utility model is provided with a centrifugal cup groove and a TF head groove for placing a centrifugal cup and a TF head, the centrifugal cup groove is also provided with a centrifugal cup cover limiting groove, when in use, a centrifugal cup cover is opened, the centrifugal cup is placed in the centrifugal cup groove, the cup cover is limited in the centrifugal cup cover limiting groove, a motor is started, the motor rotates, the centrifugal cup and the TF head pass through a detection sensor respectively to detect whether the centrifugal cup groove and the TF head groove have the centrifugal cup and the TF head groove, then the TF head rotates to a sampling position, the TF head is connected to a sampling instrument, then the centrifugal cup is positioned at the sampling position by rotating a disk body, thus the centrifugal cup and the TF head can be easily sampled from the centrifugal cup without finding out the centrifugal cup and the TF head manually, the centrifugal cup and the TF head do not need to be fixed manually, only the TF head and the centrifugal cup are placed in the corresponding grooves, the whole blood sample preparation action can be realized, and the automatic sampling of the, need not the manual work to put the centrifugal cup into the sample position and supply the sampling instrument sample, through this carousel, can carry out the serialization preparation blood sample moreover, improve sampling efficiency, also provide basic guarantee for realizing full-automatic sample.
Drawings
FIG. 1 is a schematic structural view of the fully automatic chemiluminescence immunoassay analyzer assembled by matching the present invention with other devices;
FIG. 2 is a schematic view of the overall structure of the present invention;
fig. 3 is a schematic structural diagram of the present invention cooperating with the sampling mechanism.
Reference numeral 1, a capillary tube supply device, 2, a capillary tube pushing device, 3, a capillary tube transfer device, 4, a reagent storage device, 5, a reagent suction device, 6, a dropping device, 7, an air blowing device, 8, a sampling device, 800, a tray body, 801, a sampling mechanism, 802, a detection sensor, 803, a rotating shaft, 804, a centrifugal cup, 805, a TF head, 9, an incubation device, 10, a detection device, 11, a capillary tube, 12 and a bottom plate.
Detailed Description
The present invention will be further described with reference to the following examples, which are only some, but not all, of the examples of the present invention. Based on the embodiments in the present invention, other embodiments used by those skilled in the art without creative work belong to the protection scope of the present invention.
Example 1
This embodiment provides a sample storage turntable, and this sample storage turntable includes disk body 800, disk body slewing mechanism and detection sensor 802, is provided with centrifugal cup groove and TF head groove on the disk body, falls into two semicircles with the disk body, and the correspondence sets up two centrifugal cup grooves on the central line, and the central line both sides set up three TF head groove respectively, and centrifugal cup inslot is used for placing centrifugal cup 804, and TF head inslot is used for placing the TF head. One of the two centrifugal cup grooves is a preparation position, the other is a sampling position, a sampling mechanism 801 is installed at the sampling position, and a blood sample is sucked from the centrifugal cup groove at the sampling position through the sampling mechanism, so that the disk body needs to be driven to rotate by the disk body rotating mechanism, the centrifugal cup is conveyed to the sampling position from the preparation position, and meanwhile, the TF head also needs to be conveyed to the sampling mechanism so as to be connected with the TF head for sampling and sampling. Through the drive of disk body slewing mechanism, can realize that automatic pickup TF head also can realize the fixed of TF head, can also realize the fixed and the sample of centrifugal cup simultaneously, no longer manual operation has improved work efficiency.
The tray body rotating mechanism comprises a rotating shaft 803 and a motor, the rotating shaft is connected with the motor, the motor drives the rotating shaft to rotate, the tray body is sleeved on the rotating shaft, and the tray body rotates along with the rotation of the rotating shaft. The detection sensor 802 is installed below the tray body and fixed on the lower side surface of the bottom plate and used for detecting whether a centrifugal cup is arranged in a centrifugal cup groove entering the detection sensor and whether a TF head is arranged in a TF head groove or not, and the rotation angle of the tray body can be controlled through the detection sensor so as to ensure that the TF head and the centrifugal cup are rotated to the lower side of the sampling mechanism and then sampling action is carried out.
The centrifugal cup 804 is internally provided with a blood sample after centrifugation, the centrifugal cup groove is provided with a centrifugal cup cover limiting groove, the centrifugal cup is placed in the centrifugal cup groove, and the centrifugal cup cover is opened and limited in the centrifugal cup cover groove.
The specific sampling steps are as follows: the centrifugal cup and the TF head are respectively placed in the centrifugal cup groove and the TF head groove of the tray body, the tray body rotates, the detection sensor detects that TF heads are arranged in the centrifugal cup groove and the TF head groove, after the rotation angle of the tray body is calculated, the TF head is rotated to the position below the sampling mechanism, the sampling mechanism is connected with the TF head, then the tray body is rotated, the centrifugal cup is rotated to the sampling position, and the sampling mechanism can complete sampling actions with the TF head.
Example 2
For the convenience of explanation the utility model discloses with other device cooperations, realize full autoanalysis's purpose, this embodiment provides a full-automatic chemiluminescence immunoassay appearance for full-automatic all steps of realizing chemiluminescence immunoassay, concrete structure is as follows:
including bottom plate 12 and waste liquid groove, the waste liquid groove is installed in the bottom plate below, installs capillary feeding device 1, capillary ejecting device 2, capillary transfer device 3, reagent strorage device 4, reagent suction means 5, dropping liquid device 6, gas blowing device 7, sampling device 8, incubation device 9 and detection device 10 above the bottom plate, capillary feeding device 1 is used for supplying the capillary that has been coated with the antibody, capillary ejecting device 2 is used for ejecting capillary 11 from capillary feeding device 1, capillary transfer device 3 is used for transporting the capillary that is ejected to dropping liquid device 6, gas blowing device 7, sampling device 8, incubation device 9 and detection device 10 department, reagent strorage device 4 is used for supplying reagent, reagent suction means 5 is used for absorbing reagent from reagent strorage device 4 to send the reagent that absorbs to dropping liquid device 6, dropping device 6 is arranged in to capillary 11 to send into the reagent, gas blowing device 7 is arranged in cleaing away the residual liquid in the capillary, sampling device 8 is used for absorbing the detection sample to send the detection sample of absorption into capillary 11 in, incubation device 9 is used for incubation capillary 11, detection device 10 is used for detecting the luminous photon number of capillary.
The coated capillary tube is placed in a capillary tube supply device, the capillary tube supply device moves to a capillary tube pushing device, the capillary tube pushing device moves to push out the capillary tube in the capillary tube supply device, the capillary tube is transported to a sampling device by a capillary tube transport device, the capillary tube sucks a sample after sampling by the sampling device, then the capillary tube is transported to an incubation device by the transport device for incubation, after the incubation is completed, the capillary tube is transported to an air blowing device by the transport device to remove residual liquid in the capillary tube, then the capillary tube is transported to a liquid dropping device to remove the residual liquid by the air blowing device after the capillary tube absorbs the cleaning liquid, the capillary tube is transported to the liquid dropping device to absorb a reactant after the capillary tube is cleaned by the cleaning liquid for a plurality of times (for example, 3 times) and the residual liquid is removed by the air blowing, and then the capillary tube is transported to the incubation device by, after the incubation is finished, the capillary tube is sent to the blowing device and the liquid dropping device again to be blown, sucked and cleaned for multiple times, the capillary tube sucks the luminescent substrate at the liquid dropping device, the capillary tube is transported to the detection device by the capillary tube transportation device, the detection device detects the capillary tube, the number of photons emitted by the capillary tube is detected, and the whole process is finished.
Through the utility model provides a deposit the carousel, can provide the blood sample for sampling mechanism, guarantee sampling mechanism can accomplish automatic sampling, improves sample efficiency.
Claims (2)
1. A sample storage rotary disk for chemiluminescence immunoassay is characterized in that: including slewing mechanism, disk body and detection sensor, slewing mechanism drive disk body rotates, be provided with centrifugation cup groove and TF head groove on the disk body, centrifugation cup groove is used for placing the centrifugation cup, TF head groove is used for placing the TF head, detection sensor installs in the disk body below.
2. The sample storage disk for chemiluminescence immunoassay according to claim 1, wherein: the centrifugal cup is internally provided with a blood sample after centrifugation, the centrifugal cup groove is provided with a centrifugal cup cover limiting groove, the centrifugal cup is placed in the centrifugal cup groove, and the centrifugal cup cover is opened and limited in the centrifugal cup cover groove.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921208642.5U CN210294300U (en) | 2019-07-30 | 2019-07-30 | Sample storage rotary disc for chemiluminescence immunoassay |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921208642.5U CN210294300U (en) | 2019-07-30 | 2019-07-30 | Sample storage rotary disc for chemiluminescence immunoassay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210294300U true CN210294300U (en) | 2020-04-10 |
Family
ID=70105115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921208642.5U Active CN210294300U (en) | 2019-07-30 | 2019-07-30 | Sample storage rotary disc for chemiluminescence immunoassay |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210294300U (en) |
-
2019
- 2019-07-30 CN CN201921208642.5U patent/CN210294300U/en active Active
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|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address |
Address after: No.1, 1st floor, building 1, No.333 Hezuo Road, high tech Zone, Chengdu, Sichuan 610000 Patentee after: Chengdu Smart Technology Co.,Ltd. Country or region after: China Address before: No.1, 1st floor, building 1, No.333 Hezuo Road, high tech Zone, Chengdu, Sichuan 610000 Patentee before: CHENGDU SEAMATY TECHNOLOGY Co.,Ltd. Country or region before: China |