CN1990006A - 一种土荆芥提取物、其制剂、制备方法与用途 - Google Patents
一种土荆芥提取物、其制剂、制备方法与用途 Download PDFInfo
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- CN1990006A CN1990006A CN 200510135358 CN200510135358A CN1990006A CN 1990006 A CN1990006 A CN 1990006A CN 200510135358 CN200510135358 CN 200510135358 CN 200510135358 A CN200510135358 A CN 200510135358A CN 1990006 A CN1990006 A CN 1990006A
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- herba chenopodii
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- extract
- oil
- volatile oil
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- 238000001694 spray drying Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
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Abstract
Description
分组 | 剂量(mg/kg) | 溃疡面积(mm2) | 溃疡区注入墨汁的体积(υl) |
模型对照组雷尼替丁土荆芥挥发油 高剂量中剂量低剂量 | -20020105 | 24.52±11.298.08±5.72**10.57±5.45**8.93±6.64**8.71±5.41** | 7.74±3.832.85±2.63**3.25±1.24**2.27±1.84**1.67±1.29*** |
分组 | 剂量(mg/kg) | 溃疡指数 |
模型对照组雷尼替丁土荆芥挥发油 高剂量中剂量低剂量 | -20020105 | 2.7±1.80.8±0.6**0.9±0.6*1.0±0.8*0.9±0.6* |
组别 | 剂量(mg/kg) | 墨汁推进百分率( X±SD %) |
对照组阿托品土荆芥挥发油 高剂量中剂量低剂量 | -1520105 | 49.25±5.8225.51±10.92***32.73±16.41*31.30±20.11*30.47±27.04 |
药物 | 药物浓度(mg/ml) | ||||||||||||
24.8 | 12.4 | 6.2 | 3.1 | 1.55 | 0.78 | 0.39 | 0.194 | 0.097 | 0.048 | 0.024 | 0.012 | 0 | |
土荆 | -- | -- | ++ | ++ | ++ |
芥油 |
Claims (16)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
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CN2005101353586A CN1990006B (zh) | 2005-12-31 | 2005-12-31 | 一种土荆芥提取物、其制剂、制备方法与用途 |
KR1020087018649A KR101164516B1 (ko) | 2005-12-31 | 2006-12-29 | 양명아주 추출물을 함유하는 약학 조성물, 및 이의 제조방법 및 용도 |
MYPI20082118A MY148473A (en) | 2005-12-31 | 2006-12-29 | Extracts of chenopodium ambrosioides l., the compositions comprising said extracts, the preparing process and application thereof |
JP2008547835A JP5844954B2 (ja) | 2005-12-31 | 2006-12-29 | アリタソウの抽出物を含有する医薬組成物、それらの製造方法 |
US12/159,609 US8361515B2 (en) | 2005-12-31 | 2006-12-29 | Extracts of Chenopodium ambrosioides L., the compositions comprising said extracts, the preparing process and application thereof |
EP06840721A EP1982705B8 (en) | 2005-12-31 | 2006-12-29 | Pharmaceutical composition containing chenopodium ambrosioides extract and its preparation process and application |
PCT/CN2006/003691 WO2007076699A1 (fr) | 2005-12-31 | 2006-12-29 | Composition pharmaceutique contenant un extrait de chenopodium ambrosioides et son procédé de préparation et son application |
RU2008130841/15A RU2423111C2 (ru) | 2005-12-31 | 2006-12-29 | ЭКСТРАКТЫ ПРИМЕНЯЕМОГО В КИТАЙСКОЙ МЕДИЦИНЕ РАСТЕНИЯ Chenopodium ambrosioides L., КОМПОЗИЦИИ, ВКЛЮЧАЮЩИЕ УПОМЯНУТЫЕ ЭКСТРАКТЫ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ |
ZA200805477A ZA200805477B (en) | 2005-12-31 | 2008-06-23 | Pharmaceutical composition containing chenopodium ambrosioides extract and its preparing process and application |
HK08111964.1A HK1119938A1 (en) | 2005-12-31 | 2008-10-30 | Pharmaceutical composition containing chenopodium ambrosioides extract and its preparation process and application |
US13/725,265 US8586108B2 (en) | 2005-12-31 | 2012-12-21 | Extracts of Chenopodium ambrosioides L., the compositions comprising said extracts, the preparing process and application thereof |
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CN2005101353586A CN1990006B (zh) | 2005-12-31 | 2005-12-31 | 一种土荆芥提取物、其制剂、制备方法与用途 |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102532155A (zh) * | 2010-12-24 | 2012-07-04 | 苏州宝泽堂医药科技有限公司 | 一种从土荆芥中提取驱蛔素及α-菠菜甾醇的方法 |
CN101639464B (zh) * | 2008-07-30 | 2012-11-28 | 天士力制药集团股份有限公司 | 分析血浆中驱蛔素含量的方法及其在药代动力学中的应用 |
US8361515B2 (en) | 2005-12-31 | 2013-01-29 | Tasly Pharmaceutical Group Co., Ltd. | Extracts of Chenopodium ambrosioides L., the compositions comprising said extracts, the preparing process and application thereof |
CN101675924B (zh) * | 2008-09-19 | 2013-06-05 | 天士力制药集团股份有限公司 | 驱蛔素在制备抗幽门螺杆菌及其引起的疾病的药物中的应用 |
CN101822665B (zh) * | 2009-03-06 | 2013-09-11 | 天士力制药集团股份有限公司 | 一种驱蛔素胃滞留制剂及其制备方法 |
CN103503925A (zh) * | 2013-09-26 | 2014-01-15 | 信阳农林学院 | 土荆芥挥发油熏蒸颗粒剂及制备方法 |
CN114392288A (zh) * | 2022-02-14 | 2022-04-26 | 楚雄医药高等专科学校 | 一种提取土荆芥中有效成分的提取方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1052646C (zh) * | 1995-03-23 | 2000-05-24 | 张涌川 | 一种治疗胃脘痛的胶丸及其制备方法 |
-
2005
- 2005-12-31 CN CN2005101353586A patent/CN1990006B/zh active Active
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8361515B2 (en) | 2005-12-31 | 2013-01-29 | Tasly Pharmaceutical Group Co., Ltd. | Extracts of Chenopodium ambrosioides L., the compositions comprising said extracts, the preparing process and application thereof |
CN101639464B (zh) * | 2008-07-30 | 2012-11-28 | 天士力制药集团股份有限公司 | 分析血浆中驱蛔素含量的方法及其在药代动力学中的应用 |
CN101675924B (zh) * | 2008-09-19 | 2013-06-05 | 天士力制药集团股份有限公司 | 驱蛔素在制备抗幽门螺杆菌及其引起的疾病的药物中的应用 |
CN101822665B (zh) * | 2009-03-06 | 2013-09-11 | 天士力制药集团股份有限公司 | 一种驱蛔素胃滞留制剂及其制备方法 |
CN102532155A (zh) * | 2010-12-24 | 2012-07-04 | 苏州宝泽堂医药科技有限公司 | 一种从土荆芥中提取驱蛔素及α-菠菜甾醇的方法 |
CN103503925A (zh) * | 2013-09-26 | 2014-01-15 | 信阳农林学院 | 土荆芥挥发油熏蒸颗粒剂及制备方法 |
CN114392288A (zh) * | 2022-02-14 | 2022-04-26 | 楚雄医药高等专科学校 | 一种提取土荆芥中有效成分的提取方法 |
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CN1990006B (zh) | 2011-10-05 |
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