CN1319524C - 姜黄油提取物滴丸及其制备方法和用途 - Google Patents
姜黄油提取物滴丸及其制备方法和用途 Download PDFInfo
- Publication number
- CN1319524C CN1319524C CNB031574734A CN03157473A CN1319524C CN 1319524 C CN1319524 C CN 1319524C CN B031574734 A CNB031574734 A CN B031574734A CN 03157473 A CN03157473 A CN 03157473A CN 1319524 C CN1319524 C CN 1319524C
- Authority
- CN
- China
- Prior art keywords
- drop pill
- oil extract
- turmeric oil
- active component
- turmerone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Images
Abstract
Description
实施例 | 姜黄油提取物 | 硬脂酸 | 吐温-80 | 维生素E | 聚乙二醇-6000 |
123 | 18.0018.0014.50 | 2.201.554.00 | 1.200.600.80 | 0.250.300.45 | 78.3579.5580.25 |
实施例 | 姜黄油提取物 | 棕榈酸 | 吐温-80 | 维生素E | 聚乙二醇-6000 |
4567 | 16.2018.0010.3010.00 | 3.202.904.301.54 | 1.303.002.801.55 | 0.400.200.250.15 | 78.9075.9082.3586.76 |
实施例 | 姜黄油提取物 | 丙二醇 | 聚乙二醇-4000 | 维生素E | 聚乙二醇-6000 |
891011 | 14.5011.0012.4010.00 | 2.34.43.31.54 | 8.005.405.001.55 | 0.20.200.300.15 | 75.0080.0079.0086.76 |
实施例 | 姜黄油提取物 | 棕榈酸 | 吐温-80 | 维生素E | 聚醚(poloxamer) |
1213 | 13.5015.00 | 0.300.30 | 86.2084.70 | ||
实施例 | 姜黄油提取物 | 丙二醇 | 聚乙二醇-4000 | 维生素E | 聚氧乙烯单硬脂酸酯(S40) |
1415 | 13.5015.00 | 0.300.30 | 86.2084.70 |
样品 | 剂量mg/kg | 给药方案 | 动物数始/终(只) | 胆汁分泌增加率% |
姜黄提取物滴丸姜黄提取物滴丸姜黄提取物滴丸对照组(去氢胆酸钠) | 453525 | 10101010 | 6/66/66/612/12 | 30.1624.3212.1831.23 |
剂量mg/kg | 动物数(只) | 瘤重(g) | 抑制率(%) | |
X | SD | |||
16012080蒸馏水对照组 | 10101010 | 1.82(1)1.94(1)2.10(1)3.11 | 0.520.510.430.88 | 41.6937.4732.65 |
剂量mg/kg | 动物数(只) | 瘤重(g) | 抑制率(%) | |
X | SD | |||
16012080蒸馏水对照组 | 10101010 | 1.89(1)2.01(1)2.19(1)3.22 | 0.500.450.800.85 | 41.4337.5732.14 |
剂量mg/kg | 动物数(只) | 瘤重(g) | 抑制率(%) | |
X | SD | |||
16012080蒸馏水对照组 | 10101010 | 2.38(1)2.43(1)2.66(1)3.92 | 0.561.290.671.43 | 41.7737.9632.23 |
剂量mg/kg | 动物数(只) | 瘤重(g) | 抑制率(%) | |
X | SD | |||
16080蒸馏水对照组 | 101010 | 1.68(1)2.10(1)3.08 | 0.880.550.57 | 42.1631.68 |
剂量mg/kg | 动物数(只) | 吞噬百分率(%) | 吞噬指数(%) | ||
X | SD | X | SD | ||
16012080蒸馏水对照组 | 10101010 | 38.30(1)31.70(1)25.2025.70 | 1.642.915.031.94 | 0.386(1)0.320(1)0.2560.252 | 0.020.030.050.02 |
剂量mg/kg | 动物数(只) | NK细胞X | 活性(%)SD |
16012080蒸馏水对照组 | 10101010 | 63.68(1)62.25(1)60.8845.25 | 18.7014.7615.8817.75 |
Claims (15)
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CN101433692B (zh) * | 2007-11-13 | 2011-08-10 | 天津天士力制药股份有限公司 | 一种姜黄的有效组分及其制备方法与用途 |
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Non-Patent Citations (5)
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姜黄属常用中药的研究进展 王琰等,中国药学杂志,第36卷第2期 2001 * |
姜黄的化学成分及药理活性研究进展 韩婷等,解放军药学学报,第17卷第2期 2001 * |
姜黄的药理作用研究概况 陈宏等,国外医学中医中药分册,第18卷第6期 1996 * |
芳姜黄酮和姜烯衍生物的合成及抗生育活性初探 严秉淳等,华东化工学院学报,第16卷第1期 1990 * |
芳姜黄酮和姜烯衍生物的合成及抗生育活性初探 严秉淳等,华东化工学院学报,第16卷第1期 1990;姜黄的化学成分及药理活性研究进展 韩婷等,解放军药学学报,第17卷第2期 2001;姜黄的药理作用研究概况 陈宏等,国外医学中医中药分册,第18卷第6期 1996;姜黄属常用中药的研究进展 王琰等,中国药学杂志,第36卷第2期 2001 * |
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