CN1976720A - 用于治疗严重急性呼吸道综合征(sars)的组合物和方法 - Google Patents

用于治疗严重急性呼吸道综合征(sars)的组合物和方法 Download PDF

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Publication number
CN1976720A
CN1976720A CNA200480013748XA CN200480013748A CN1976720A CN 1976720 A CN1976720 A CN 1976720A CN A200480013748X A CNA200480013748X A CN A200480013748XA CN 200480013748 A CN200480013748 A CN 200480013748A CN 1976720 A CN1976720 A CN 1976720A
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CN
China
Prior art keywords
tnf
sars
inhibitor
composition
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA200480013748XA
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English (en)
Chinese (zh)
Inventor
G·R·锡伯
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Wyeth Holdings LLC
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Wyeth Holdings LLC
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Filing date
Publication date
Application filed by Wyeth Holdings LLC filed Critical Wyeth Holdings LLC
Publication of CN1976720A publication Critical patent/CN1976720A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA200480013748XA 2003-05-20 2004-05-20 用于治疗严重急性呼吸道综合征(sars)的组合物和方法 Pending CN1976720A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/441,059 US7892563B2 (en) 2003-05-20 2003-05-20 Methods for treatment of severe acute respiratory syndrome (SARS)
US10/441,059 2003-05-20

Publications (1)

Publication Number Publication Date
CN1976720A true CN1976720A (zh) 2007-06-06

Family

ID=33449934

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA200480013748XA Pending CN1976720A (zh) 2003-05-20 2004-05-20 用于治疗严重急性呼吸道综合征(sars)的组合物和方法

Country Status (14)

Country Link
US (2) US7892563B2 (enExample)
EP (1) EP1624850A4 (enExample)
JP (1) JP2007525465A (enExample)
KR (1) KR20060023968A (enExample)
CN (1) CN1976720A (enExample)
AU (1) AU2004266111B8 (enExample)
BR (1) BRPI0410467A (enExample)
CA (1) CA2526431A1 (enExample)
IL (1) IL171972A0 (enExample)
MX (1) MXPA05012497A (enExample)
NO (1) NO20056073L (enExample)
NZ (1) NZ543655A (enExample)
RU (1) RU2411042C2 (enExample)
WO (1) WO2005018535A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111228480A (zh) * 2020-02-24 2020-06-05 浙江正熙生物医药有限公司 抗人TNF-α抗体在制备用于治疗病毒感染的药物中的应用
CN113425722A (zh) * 2020-03-23 2021-09-24 上海市浦东新区公利医院(第二军医大学附属公利医院) 苦味受体激动剂及其在预防和治疗SARS-CoV-2相关传染病中的应用
CN115996741A (zh) * 2020-03-11 2023-04-21 百欧林纳克斯有限公司 用于治疗急性呼吸窘迫综合征及病毒感染的cxcr4抑制剂
CN116133657A (zh) * 2020-05-07 2023-05-16 4活性生物科技公司 治疗covid-19疾病的新组合物和方法

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JP4845091B2 (ja) * 2005-08-09 2011-12-28 学校法人日本大学 コロナウィルスの遺伝子を切断するリボザイム
CA2651775A1 (en) * 2006-05-08 2008-05-08 University Of Virginia Patent Foundation Compositions and methods for treating anthrax lethality
US8637469B2 (en) * 2006-07-11 2014-01-28 Roy C. Levitt Rhinosinusitis prevention and therapy with proinflammatory cytokine inhibitors
JP2013512674A (ja) * 2009-12-02 2013-04-18 アクセルロン ファーマ， インコーポレイテッド Ｆｃ融合タンパク質の血清半減期を増加させるための組成物および方法
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EP3957364A1 (en) * 2020-08-20 2022-02-23 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. A binding molecule specifically binding to human cd4 for use in the treatment of pulmonary diseases
US20220273641A1 (en) * 2020-10-07 2022-09-01 Vera Mikhailov Method for treating coronavirus infections including SARS-CoV-2
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111228480A (zh) * 2020-02-24 2020-06-05 浙江正熙生物医药有限公司 抗人TNF-α抗体在制备用于治疗病毒感染的药物中的应用
CN115996741A (zh) * 2020-03-11 2023-04-21 百欧林纳克斯有限公司 用于治疗急性呼吸窘迫综合征及病毒感染的cxcr4抑制剂
CN113425722A (zh) * 2020-03-23 2021-09-24 上海市浦东新区公利医院(第二军医大学附属公利医院) 苦味受体激动剂及其在预防和治疗SARS-CoV-2相关传染病中的应用
CN116133657A (zh) * 2020-05-07 2023-05-16 4活性生物科技公司 治疗covid-19疾病的新组合物和方法

Also Published As

Publication number Publication date
RU2411042C2 (ru) 2011-02-10
RU2005139730A (ru) 2006-05-10
JP2007525465A (ja) 2007-09-06
EP1624850A4 (en) 2007-10-31
MXPA05012497A (es) 2006-07-03
NO20056073L (no) 2005-12-20
IL171972A0 (en) 2006-04-10
US20040235047A1 (en) 2004-11-25
WO2005018535A2 (en) 2005-03-03
US20060263847A1 (en) 2006-11-23
US7722886B2 (en) 2010-05-25
NZ543655A (en) 2009-07-31
US7892563B2 (en) 2011-02-22
KR20060023968A (ko) 2006-03-15
AU2004266111A1 (en) 2005-03-03
AU2004266111B2 (en) 2010-08-26
CA2526431A1 (en) 2005-03-03
WO2005018535A3 (en) 2006-12-21
EP1624850A2 (en) 2006-02-15
AU2004266111B8 (en) 2010-12-23
BRPI0410467A (pt) 2006-05-30

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