DE69232586T2 - Giftigkeit von tnf und lps ausschaltende peptide - Google Patents

Giftigkeit von tnf und lps ausschaltende peptide

Info

Publication number
DE69232586T2
DE69232586T2 DE69232586T DE69232586T DE69232586T2 DE 69232586 T2 DE69232586 T2 DE 69232586T2 DE 69232586 T DE69232586 T DE 69232586T DE 69232586 T DE69232586 T DE 69232586T DE 69232586 T2 DE69232586 T2 DE 69232586T2
Authority
DE
Germany
Prior art keywords
lps
tnf
disabling
peptides
toxicity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69232586T
Other languages
English (en)
Other versions
DE69232586D1 (de
Inventor
Ann Rathjen
Fred Widmer
Walter Grigg
On-Lok Mack
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceuticals Australia Pty Ltd
Original Assignee
Peptech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peptech Ltd filed Critical Peptech Ltd
Application granted granted Critical
Publication of DE69232586D1 publication Critical patent/DE69232586D1/de
Publication of DE69232586T2 publication Critical patent/DE69232586T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE69232586T 1991-07-05 1992-07-03 Giftigkeit von tnf und lps ausschaltende peptide Expired - Fee Related DE69232586T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPK709791 1991-07-05
AUPK792491 1991-08-22
PCT/AU1992/000332 WO1993001211A1 (en) 1991-07-05 1992-07-03 Peptide which abrogates tnf and/or lps toxicity

Publications (2)

Publication Number Publication Date
DE69232586D1 DE69232586D1 (de) 2002-06-06
DE69232586T2 true DE69232586T2 (de) 2002-11-28

Family

ID=25644068

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69232586T Expired - Fee Related DE69232586T2 (de) 1991-07-05 1992-07-03 Giftigkeit von tnf und lps ausschaltende peptide

Country Status (7)

Country Link
US (1) US5795859A (de)
EP (1) EP0593585B1 (de)
JP (1) JP3534748B2 (de)
CA (1) CA2112907C (de)
DE (1) DE69232586T2 (de)
DK (1) DK0593585T3 (de)
WO (1) WO1993001211A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5587457A (en) * 1990-03-12 1996-12-24 Peptide Technology Limited Neutrophil stimulating peptides
US6375928B1 (en) * 1990-03-12 2002-04-23 Peptech Limited Neutrophil stimulating peptides
IT1254315B (it) * 1992-03-27 1995-09-14 Mini Ricerca Scient Tecnolog Anticorpi monoclonali anti-idiotipici diretti contro anticorpi anti-tnf.
US5457129A (en) * 1993-05-17 1995-10-10 Research Development Foundation Inhibition of nitric oxide production by retinoic acid
US6107273A (en) * 1995-01-24 2000-08-22 Thomas Jefferson University Tumor necrosis factor inhibitors
US6107457A (en) * 1995-02-16 2000-08-22 Board Of Regents, The University Of Texas System Bcr-Abl directed compositions and uses for inhibiting Philadelphia chromosome stimulated cell growth
US7244710B2 (en) 2002-05-21 2007-07-17 Zengen, Inc. Treatment of ophthalmic infections using antimicrobial peptides
US6803044B1 (en) 1999-03-24 2004-10-12 Zengen, Inc. Antimicrobial and anti-inflammatory peptides for use in human immunodeficiency virus
US6800291B1 (en) * 1999-03-24 2004-10-05 Zengen, Inc. Uro-genital condition treatment system
US7402559B2 (en) 1999-03-24 2008-07-22 Msh Pharma, Incorporated Composition and method of treatment for urogenital conditions
US20040220103A1 (en) * 1999-04-19 2004-11-04 Immunex Corporation Soluble tumor necrosis factor receptor treatment of medical disorders
AU2001297591A1 (en) * 2000-11-01 2002-09-19 Zengen, Inc. A sunburn treatment and sunburn prevention method
US6780838B2 (en) 2001-01-29 2004-08-24 Zengen, Inc. Compounds for treating fungal pathologies of the oral cavity
US6894028B2 (en) 2001-04-06 2005-05-17 Zengen, Inc. Use of KPV tripeptide for dermatological disorders
US7115574B2 (en) 2001-12-10 2006-10-03 Zengen, Inc. System and method for support legacy operating system booting in a legacy-free system
US6939846B2 (en) 2001-12-17 2005-09-06 Zengen, Inc. Use of a polypeptide for treatment of pruritis in animals
US7892563B2 (en) * 2003-05-20 2011-02-22 Wyeth Holdings Corporation Methods for treatment of severe acute respiratory syndrome (SARS)
MXPA06009805A (es) * 2004-02-27 2007-04-02 Vaxconsulting Peptidos de interleucina 1 beta y factor de necrosis tumoral alfa y metodo de tratamiento utilizando los mismos.
WO2007009233A2 (en) * 2005-07-18 2007-01-25 University Of Manitoba Peptide-based cytokine vaccines in the treatment of autoimmune and inflammatory diseases
EP2948178A4 (de) * 2013-01-25 2016-07-20 Thymon Llc Zusammensetzungen zur selektiven reduktion von zirkulierendem bioaktivem löslichem tnf und verfahren zur behandlung einer tnf-vermittelten erkrankung

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB313654A (en) * 1928-03-16 1929-06-17 Shell Mex Ltd Improvements in or relating to plug cocks
US4508728A (en) * 1984-05-24 1985-04-02 Kineshiro Nagai Method of treating inflammatory diseases
JPS61186322A (ja) * 1985-02-13 1986-08-20 Nippon Univ 免疾調節剤
JPH07116160B2 (ja) * 1987-08-10 1995-12-13 浜理薬品工業株式会社 結晶性ｌ−カルノシン亜鉛錯体およびその製造法
JP2828988B2 (ja) * 1988-04-03 1998-11-25 源一郎 杣 新規ｄｎａとその生産方法、それを有する新規プラスミド、新規ポリペプチドとその生産方法、及び該ポリペプチドからなる新規抗腫瘍剤
DE3817955A1 (de) * 1988-05-27 1989-11-30 Hoechst Ag Tnf-inhibitor enthaltendes arzneimittel
WO1990006102A1 (en) * 1988-09-28 1990-06-14 Peptide Technology Limited Compound and method for the retardation of collagen cross-linking
DE3841767A1 (de) * 1988-12-12 1990-06-13 Basf Ag Neue tnf-peptide
DE3841755A1 (de) * 1988-12-12 1990-06-13 Basf Ag Neue tnf-peptide
AU640400B2 (en) * 1989-08-07 1993-08-26 Peptide Technology Ltd. Tumour necrosis factor binding ligands
AU5940090A (en) * 1989-08-16 1991-04-03 Cetus Oncology Corporation Compositions for the inhibition of protein hormone formation and uses thereof
GB9028123D0 (en) * 1990-12-28 1991-02-13 Erba Carlo Spa Monoclonal antibodies against human tumor necrosis factor alpha
JPH07508650A (ja) * 1992-06-25 1995-09-28 カイロン　コーポレーション タンパク質ホルモン形成の阻害のための組成物およびその使用

Also Published As

Publication number Publication date
AU673332B2 (en) 1996-11-07
JPH07502978A (ja) 1995-03-30
EP0593585A4 (de) 1995-01-18
DK0593585T3 (da) 2002-08-19
WO1993001211A1 (en) 1993-01-21
US5795859A (en) 1998-08-18
EP0593585A1 (de) 1994-04-27
DE69232586D1 (de) 2002-06-06
JP3534748B2 (ja) 2004-06-07
AU2273192A (en) 1993-02-11
CA2112907A1 (en) 1993-01-21
EP0593585B1 (de) 2002-05-02
CA2112907C (en) 2003-09-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: GRAF VON STOSCH PATENTANWALTSGESELLSCHAFT MBH, 805

8339 Ceased/non-payment of the annual fee