CN1964981A - 3-链烯基头孢烯化合物的制造方法 - Google Patents
3-链烯基头孢烯化合物的制造方法 Download PDFInfo
- Publication number
- CN1964981A CN1964981A CNA2005800177369A CN200580017736A CN1964981A CN 1964981 A CN1964981 A CN 1964981A CN A2005800177369 A CNA2005800177369 A CN A2005800177369A CN 200580017736 A CN200580017736 A CN 200580017736A CN 1964981 A CN1964981 A CN 1964981A
- Authority
- CN
- China
- Prior art keywords
- formula
- carboxylic acid
- alkali metal
- cephem
- methylthiazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (8)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP167581/2004 | 2004-06-04 | ||
JP2004167581A JP4046708B2 (ja) | 2004-06-04 | 2004-06-04 | 3−アルケニルセフェム化合物の製造方法 |
PCT/JP2005/010621 WO2005118595A1 (ja) | 2004-06-04 | 2005-06-03 | 3−アルケニルセフェム化合物の製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1964981A true CN1964981A (zh) | 2007-05-16 |
CN1964981B CN1964981B (zh) | 2011-08-17 |
Family
ID=35462876
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2005800177369A Active CN1964981B (zh) | 2004-06-04 | 2005-06-03 | 3-链烯基头孢烯化合物的制造方法 |
Country Status (8)
Country | Link |
---|---|
US (1) | US7893254B2 (zh) |
EP (1) | EP1752459B1 (zh) |
JP (1) | JP4046708B2 (zh) |
KR (2) | KR100882067B1 (zh) |
CN (1) | CN1964981B (zh) |
ES (1) | ES2632500T3 (zh) |
HK (1) | HK1105968A1 (zh) |
WO (1) | WO2005118595A1 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102725297A (zh) * | 2010-01-27 | 2012-10-10 | 日本化学工业株式会社 | 头孢菌素衍生物的制造方法 |
CN101628915B (zh) * | 2008-07-15 | 2014-04-02 | 日本化学工业株式会社 | 3-链烯基头孢烯化合物的制造方法 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7459550B2 (en) * | 2003-07-04 | 2008-12-02 | Orchid Chemicals & Pharmaceuticals Ltd. | Process for the preparation of Cefditoren |
JP4064948B2 (ja) * | 2004-06-04 | 2008-03-19 | 明治製菓株式会社 | 3−アルケニルセフェム化合物及び製造方法 |
CN101735248A (zh) * | 2008-11-07 | 2010-06-16 | 日本化学工业株式会社 | 3-链烯基头孢烯化合物的制造方法 |
KR101618874B1 (ko) * | 2008-11-07 | 2016-05-09 | 니폰 가가쿠 고교 가부시키가이샤 | 3-알케닐세펨 화합물의 제조 방법 |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3979383A (en) * | 1975-03-07 | 1976-09-07 | Eli Lilly And Company | Purification process for 7-aminocephalosporins |
DE2620094A1 (de) * | 1975-05-12 | 1976-12-02 | Takeda Chemical Industries Ltd | Cephalosporinverbindungen und verfahren zu ihrer herstellung |
US4311698A (en) * | 1979-03-12 | 1982-01-19 | Haskell Theodore H | Aminoacid derivatives of cephalosporin compounds |
JPS5643288A (en) * | 1979-09-18 | 1981-04-21 | Meiji Seika Kaisha Ltd | Cephalosporin derivative and its preparation |
EP0081971A3 (en) * | 1981-12-08 | 1984-09-26 | Tanabe Seiyaku Co., Ltd. | Novel cephalosporin compound and process for preparing the same |
US4699979A (en) * | 1985-04-22 | 1987-10-13 | Bristol-Meyers Company | 7-amino-3-propenylcephalosporanic acid and esters thereof |
FR2580652B1 (fr) * | 1985-04-22 | 1989-01-06 | Bristol Myers Co | Acide 7-amino-3-propenylcephalosporanique et ses esters |
CN1012812B (zh) * | 1986-01-31 | 1991-06-12 | 三菱化成株式会社 | 镓的回收方法 |
US5061371A (en) * | 1990-04-06 | 1991-10-29 | Nippon Rensui Co. | Chromatographic separation apparatus |
DE4026630A1 (de) * | 1990-08-23 | 1992-02-27 | Hoechst Ag | Verfahren zur herstellung von kristalliner tacs |
IT1252308B (it) * | 1990-12-21 | 1995-06-08 | Antibioticos Spa | Procedimento enzimatico per la produzione di acido 7- amminocefalosporanico e derivati |
US5194371A (en) * | 1991-07-31 | 1993-03-16 | Bristol-Myers Squibb Company | Production of pradimicin antibiotics |
JPH0798752B2 (ja) * | 1991-08-09 | 1995-10-25 | 株式会社ツムラ | β−グルクロニダーゼ阻害剤 |
KR950700311A (ko) * | 1992-02-05 | 1995-01-16 | 게오르게스 그렐리니, 한스 루돌프하우스 | 3-세펨-4-카복실산 유도체의 정제방법(Process for the purification of a 3-cephem-4-carboxylic acid derivatives) |
ATE198892T1 (de) * | 1993-11-17 | 2001-02-15 | Biochemie Gmbh | Trennung von cephalosporinisomeren |
WO1997047209A1 (fr) * | 1996-06-12 | 1997-12-18 | Kyowa Hakko Kogyo Co., Ltd. | Amelioration du metabolisme lipidique |
JPH10101679A (ja) * | 1996-10-02 | 1998-04-21 | Otsuka Chem Co Ltd | セファゾリンの製造法 |
PT1016665E (pt) * | 1997-06-24 | 2002-12-31 | Meiji Seika Kaisha | Processo para a preparacao selectiva de isomeros z de 3-(2-vinil-substituido) cefalosporinas |
JPH11171895A (ja) * | 1997-12-11 | 1999-06-29 | Ajinomoto Co Inc | アスパルテームとアスパルテーム誘導体の分離精製方法 |
US5945542A (en) * | 1998-02-26 | 1999-08-31 | Robert L. Pollack | Isolation of natural L-β-3-indolylalanine and enrichment of natural aliphatic amino acid mixtures with natural L-β-3-indolylalanine |
JP2002522072A (ja) * | 1998-08-12 | 2002-07-23 | マキシジェン, インコーポレイテッド | 工業用化学薬品の製造のためのモノオキシゲナーゼ遺伝子のdnaシャッフリング。 |
US6407091B1 (en) * | 1999-04-15 | 2002-06-18 | Research Corporation Technologies, Inc. | β-lactamase inhibiting compounds |
EP1316314A4 (en) * | 2000-08-31 | 2004-12-29 | Kitasato Inst | PREPARATION OF A VACCINE CONTAINING FATTY ACID AS A COMPOUND |
JP4401775B2 (ja) * | 2001-10-25 | 2010-01-20 | 協和発酵バイオ株式会社 | 酸化型グルタチオンの結晶およびその製造方法 |
JP2005516972A (ja) * | 2002-01-22 | 2005-06-09 | ファイザー・インク | 血栓疾患の治療のためのtafi−a阻害剤として使用される3−(イミダゾリル)−2−アミノプロピオン酸 |
WO2003064538A1 (fr) * | 2002-02-01 | 2003-08-07 | San-Ei Gen F.F.I., Inc. | Couleur de mais rouge purifiee et procede de preparation de celle-ci |
TWI344371B (en) * | 2003-03-18 | 2011-07-01 | Suntory Holdings Ltd | Angiotensin-converting enzyme inhibitory peptides |
US20080249163A1 (en) * | 2003-10-01 | 2008-10-09 | Kinya Takagaki | Process For Producing Product Containing Proanthocyanidin in High Proportion |
US7087423B2 (en) * | 2003-12-23 | 2006-08-08 | Dainippon Ink And Chemicals, Inc. | Process for producing sporangia of Bacillus popilliae |
JP4064948B2 (ja) * | 2004-06-04 | 2008-03-19 | 明治製菓株式会社 | 3−アルケニルセフェム化合物及び製造方法 |
EP1693471A1 (en) * | 2005-02-16 | 2006-08-23 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Method for refining a liquor, comprising an aqueous solution of a carbohydrate |
EP1870457A4 (en) * | 2005-03-29 | 2012-02-22 | Kyowa Hakko Bio Co Ltd | DIPEPTIDE CRYSTAL AND METHOD FOR THE PRODUCTION THEREOF |
TW200741005A (en) * | 2005-08-10 | 2007-11-01 | Kyowa Hakko Kogyo Kk | A purification method of cytidine diphosphate |
US20070161784A1 (en) * | 2006-01-11 | 2007-07-12 | Aminopath Labs, Llc | Methods and products of amino acid isolation |
-
2004
- 2004-06-04 JP JP2004167581A patent/JP4046708B2/ja not_active Expired - Lifetime
-
2005
- 2005-06-03 US US11/628,248 patent/US7893254B2/en active Active
- 2005-06-03 ES ES05751538.9T patent/ES2632500T3/es active Active
- 2005-06-03 WO PCT/JP2005/010621 patent/WO2005118595A1/ja active Application Filing
- 2005-06-03 KR KR1020087021768A patent/KR100882067B1/ko active IP Right Grant
- 2005-06-03 EP EP05751538.9A patent/EP1752459B1/en active Active
- 2005-06-03 KR KR1020077000096A patent/KR100870804B1/ko active IP Right Grant
- 2005-06-03 CN CN2005800177369A patent/CN1964981B/zh active Active
-
2007
- 2007-10-18 HK HK07111290.7A patent/HK1105968A1/xx unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101628915B (zh) * | 2008-07-15 | 2014-04-02 | 日本化学工业株式会社 | 3-链烯基头孢烯化合物的制造方法 |
CN102725297A (zh) * | 2010-01-27 | 2012-10-10 | 日本化学工业株式会社 | 头孢菌素衍生物的制造方法 |
Also Published As
Publication number | Publication date |
---|---|
EP1752459B1 (en) | 2017-05-10 |
KR100870804B1 (ko) | 2008-11-27 |
JP2005343854A (ja) | 2005-12-15 |
EP1752459A1 (en) | 2007-02-14 |
HK1105968A1 (en) | 2008-02-29 |
KR100882067B1 (ko) | 2009-02-10 |
US20080033166A1 (en) | 2008-02-07 |
ES2632500T3 (es) | 2017-09-13 |
US7893254B2 (en) | 2011-02-22 |
WO2005118595A1 (ja) | 2005-12-15 |
JP4046708B2 (ja) | 2008-02-13 |
KR20080086554A (ko) | 2008-09-25 |
EP1752459A4 (en) | 2008-01-02 |
KR20070030261A (ko) | 2007-03-15 |
CN1964981B (zh) | 2011-08-17 |
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Address after: Osaka Japan Patentee after: Otsuka Chemical Co., Ltd. Patentee after: Meiji Seika Pharma Co., Ltd. Address before: Osaka Japan Patentee before: Otsuka Chemical Co., Ltd. Patentee before: Meiji Seika Kaisha, Ltd. |