CN1950376A - 莪术醇衍生物、含该衍生物的组合物及所述衍生物的制药用途 - Google Patents
莪术醇衍生物、含该衍生物的组合物及所述衍生物的制药用途 Download PDFInfo
- Publication number
- CN1950376A CN1950376A CNA2005800144098A CN200580014409A CN1950376A CN 1950376 A CN1950376 A CN 1950376A CN A2005800144098 A CNA2005800144098 A CN A2005800144098A CN 200580014409 A CN200580014409 A CN 200580014409A CN 1950376 A CN1950376 A CN 1950376A
- Authority
- CN
- China
- Prior art keywords
- rcumenol
- pharmaceutically acceptable
- acceptable salt
- compound
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/20—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Claims (1)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNA2004100443364A CN1704417A (zh) | 2004-05-26 | 2004-05-26 | 新化合物莪术醇衍生物 |
CN200410044336.4 | 2004-05-26 | ||
PCT/CN2005/000730 WO2005116036A1 (en) | 2004-05-26 | 2005-05-26 | Curcumol derivatives, the compositions comprising the same and the use of the same in the manufacture of medicament |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1950376A true CN1950376A (zh) | 2007-04-18 |
CN1950376B CN1950376B (zh) | 2010-09-08 |
Family
ID=35450829
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA2004100443364A Pending CN1704417A (zh) | 2004-05-26 | 2004-05-26 | 新化合物莪术醇衍生物 |
CN2005800144098A Expired - Fee Related CN1950376B (zh) | 2004-05-26 | 2005-05-26 | 莪术醇衍生物、含该衍生物的组合物及所述衍生物的制药用途 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA2004100443364A Pending CN1704417A (zh) | 2004-05-26 | 2004-05-26 | 新化合物莪术醇衍生物 |
Country Status (4)
Country | Link |
---|---|
US (1) | US7700584B2 (zh) |
EP (1) | EP1749830B1 (zh) |
CN (2) | CN1704417A (zh) |
WO (1) | WO2005116036A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114315855A (zh) * | 2022-02-09 | 2022-04-12 | 贵州省中国科学院天然产物化学重点实验室 | 莪术醇类衍生物、制备方法及其在制备抗炎药物中的应用 |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1995056B (zh) * | 2006-10-31 | 2011-06-15 | 温州医学院 | 新的莪术醇糖苷类化合物及其制备与应用 |
ES2393877T3 (es) * | 2008-01-04 | 2012-12-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Derivados de epoxi-guayano y tratamiento del cáncer |
TWI427117B (zh) | 2008-05-30 | 2014-02-21 | Nitto Denko Corp | 光學元件用樹脂組成物、使用其之光學元件及光學鏡片之製造方法 |
CN101538259A (zh) * | 2009-04-17 | 2009-09-23 | 杭州民生药业集团有限公司 | 蓬莪术环二烯的晶型a、其制备方法及其在制备抗肿瘤药物中的应用 |
CN101671345B (zh) * | 2009-09-28 | 2011-06-15 | 桂林医学院 | 一种莪术醇半抗原和人工抗原及其制备方法 |
CN102584847B (zh) * | 2012-03-09 | 2015-03-25 | 沈阳药科大学 | 一种抗单纯疱疹病毒hsv的莪术醇衍生物 |
CN102584846B (zh) * | 2012-03-09 | 2015-03-25 | 沈阳药科大学 | 一种抗甲型h1n1流感病毒的莪术醇衍生物 |
CN102759625A (zh) * | 2012-07-26 | 2012-10-31 | 桂林医学院 | 莪术醇单克隆抗体在含莪术醇类中药中的免疫分析应用 |
JP6255031B2 (ja) * | 2012-11-15 | 2017-12-27 | アメリカ合衆国 | Hiv及びhtlvに感染した患者を治療する方法 |
CN106344553B (zh) * | 2016-08-03 | 2019-12-13 | 江西省妇幼保健院 | 莪术醇在制备用于通过干预子宫内膜间质细胞而达到治疗子宫腺肌病的药物中的用途 |
CN106674242B (zh) * | 2016-11-21 | 2018-11-30 | 辽宁大学 | 一种具有抗肿瘤活性的莪术醇衍生物及其制备方法和应用 |
CN106632383B (zh) * | 2016-11-21 | 2018-08-14 | 辽宁大学 | 莪术醇衍生物及其制备方法和在抗肿瘤药物中的应用 |
CN106800560B (zh) * | 2016-12-23 | 2018-11-02 | 中国医学科学院药用植物研究所 | 莪术醇衍生物及其制备方法和应用 |
CN107828401B (zh) * | 2017-06-08 | 2020-07-14 | 中国石油化工股份有限公司 | 一种增强co2与原油互溶、降低原油粘度的驱油添加剂 |
CN107828402B (zh) * | 2017-06-08 | 2020-07-14 | 中国石油化工股份有限公司 | 一种提高深层稠油co2气驱过程采收率的化学添加剂 |
CN110604732B (zh) * | 2019-09-20 | 2022-10-14 | 浙江工业大学 | 一种莪术醇衍生物在制备治疗结直肠癌药物中的应用 |
CN111153912B (zh) * | 2019-12-31 | 2021-04-06 | 浙江工业大学 | 一种含三氮唑结构的莪术醇衍生物及其在制备治疗人结直肠癌药物中的应用 |
CN115433203A (zh) * | 2021-06-01 | 2022-12-06 | 华东理工大学 | 一种胺氟化莪术醇衍生化合物及及其应用与制备方法 |
CN113336765B (zh) * | 2021-06-16 | 2022-11-25 | 浙江工业大学 | 一种莪术醇酯化物、制备方法及其在治疗结直肠癌药物中的应用 |
CN113866319B (zh) * | 2021-10-25 | 2022-05-31 | 广西壮族自治区海洋环境监测中心站 | 一种类固醇激素的检测方法 |
CN116173159B (zh) * | 2021-11-28 | 2024-02-02 | 北京中医药大学东直门医院 | 莪术油磺化物及制备方法及应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4003951A (en) * | 1972-06-05 | 1977-01-18 | Givaudan Corporation | Octahydroazulenols |
CH571863A5 (zh) * | 1972-06-05 | 1976-01-30 | Givaudan & Cie Sa | |
US20040192641A1 (en) * | 2003-03-14 | 2004-09-30 | Yaguang Liu | Special preparation of anticancer drugs made by novel nanotechnology |
-
2004
- 2004-05-26 CN CNA2004100443364A patent/CN1704417A/zh active Pending
-
2005
- 2005-05-26 CN CN2005800144098A patent/CN1950376B/zh not_active Expired - Fee Related
- 2005-05-26 US US11/568,770 patent/US7700584B2/en not_active Expired - Fee Related
- 2005-05-26 WO PCT/CN2005/000730 patent/WO2005116036A1/zh active Application Filing
- 2005-05-26 EP EP05749349.6A patent/EP1749830B1/en not_active Not-in-force
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114315855A (zh) * | 2022-02-09 | 2022-04-12 | 贵州省中国科学院天然产物化学重点实验室 | 莪术醇类衍生物、制备方法及其在制备抗炎药物中的应用 |
Also Published As
Publication number | Publication date |
---|---|
EP1749830B1 (en) | 2013-12-11 |
WO2005116036A1 (en) | 2005-12-08 |
US7700584B2 (en) | 2010-04-20 |
CN1950376B (zh) | 2010-09-08 |
EP1749830A4 (en) | 2008-01-09 |
US20070191360A1 (en) | 2007-08-16 |
CN1704417A (zh) | 2005-12-07 |
EP1749830A1 (en) | 2007-02-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20081219 Address after: No. 108 Tong Road, Hangzhou, Zhejiang, Yuhang, China Applicant after: Hangzhou people's livelihood Pharmaceutical Group Co., Ltd. Co-applicant after: Minsheng Pharmaceutical Group Shaoxing Medicine Co., Ltd. Address before: No. 108 Tong Road, Hangzhou, Zhejiang, Yuhang, China Applicant before: Hangzhou Minsheng Pharmaceutical Group Co., Ltd. |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100908 Termination date: 20160526 |