CN1871359A - 使用单倍体交配策略在酵母中合成异聚多亚基多肽的方法 - Google Patents
使用单倍体交配策略在酵母中合成异聚多亚基多肽的方法 Download PDFInfo
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- CN1871359A CN1871359A CNA2004800312173A CN200480031217A CN1871359A CN 1871359 A CN1871359 A CN 1871359A CN A2004800312173 A CNA2004800312173 A CN A2004800312173A CN 200480031217 A CN200480031217 A CN 200480031217A CN 1871359 A CN1871359 A CN 1871359A
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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Abstract
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Claims (21)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201010512807.5A CN101979650B (zh) | 2003-10-22 | 2004-10-22 | 使用单倍体交配策略在酵母中合成异聚多亚基多肽的方法 |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51387603P | 2003-10-22 | 2003-10-22 | |
US60/513,876 | 2003-10-22 | ||
PCT/US2004/035302 WO2005040395A1 (en) | 2003-10-22 | 2004-10-22 | Methods of synthesizing heteromultimeric polypeptides in yeast using a haploid mating strategy |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201010512807.5A Division CN101979650B (zh) | 2003-10-22 | 2004-10-22 | 使用单倍体交配策略在酵母中合成异聚多亚基多肽的方法 |
Publications (2)
Publication Number | Publication Date |
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CN1871359A true CN1871359A (zh) | 2006-11-29 |
CN1871359B CN1871359B (zh) | 2010-11-17 |
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ID=34520146
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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CN201010512807.5A Active CN101979650B (zh) | 2003-10-22 | 2004-10-22 | 使用单倍体交配策略在酵母中合成异聚多亚基多肽的方法 |
CN2004800312173A Active CN1871359B (zh) | 2003-10-22 | 2004-10-22 | 使用单倍体交配策略在酵母中合成异聚多亚基多肽的方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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CN201010512807.5A Active CN101979650B (zh) | 2003-10-22 | 2004-10-22 | 使用单倍体交配策略在酵母中合成异聚多亚基多肽的方法 |
Country Status (17)
Country | Link |
---|---|
US (7) | US8268582B2 (zh) |
EP (2) | EP2330201B1 (zh) |
JP (3) | JP4994038B2 (zh) |
CN (2) | CN101979650B (zh) |
AU (2) | AU2004283299B2 (zh) |
CA (1) | CA2541651C (zh) |
DK (2) | DK1678314T3 (zh) |
ES (2) | ES2393555T3 (zh) |
HK (1) | HK1093222A1 (zh) |
HU (1) | HUE033349T2 (zh) |
IL (2) | IL174783A (zh) |
NO (1) | NO20062134L (zh) |
NZ (1) | NZ547279A (zh) |
PL (1) | PL1678314T3 (zh) |
PT (1) | PT1678314E (zh) |
SI (1) | SI1678314T1 (zh) |
WO (1) | WO2005040395A1 (zh) |
Cited By (4)
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CN103710278A (zh) * | 2013-12-25 | 2014-04-09 | 江南大学 | 一种低产尿素的工业黄酒酵母代谢工程菌及其构建方法 |
CN103911371A (zh) * | 2013-01-05 | 2014-07-09 | 中国科学院微生物研究所 | 一种酿酒酵母整合型表达载体 |
US9139825B2 (en) | 2009-10-30 | 2015-09-22 | Novartis Ag | Universal fibronectin type III bottom-side binding domain libraries |
CN108424452A (zh) * | 2011-05-20 | 2018-08-21 | 奥尔德生物控股有限责任公司 | 抗cgrp组合物及其用途 |
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AU2007307324B2 (en) * | 2006-05-19 | 2013-08-15 | Alder Biopharmaceuticals, Inc. | Culture method for obtaining a clonal population of antigen-specific B cells |
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US8232372B2 (en) | 2006-12-14 | 2012-07-31 | Schering Corp. | Engineered anti-TSLP antibody |
JP2010517577A (ja) * | 2007-02-09 | 2010-05-27 | メディミューン,エルエルシー | 酵母細胞原形質膜による抗体ライブラリー提示 |
AU2008218968B2 (en) | 2007-02-23 | 2013-10-17 | Merck Sharp & Dohme Llc | Engineered anti-IL-23p19 antibodies |
US20100111966A1 (en) | 2007-02-23 | 2010-05-06 | Schering Corporation | Engineered anti-il-23p19 antibodies |
JP5238723B2 (ja) | 2007-02-28 | 2013-07-17 | メルク・シャープ・アンド・ドーム・コーポレーション | 操作された抗il−23r抗体 |
KR101615715B1 (ko) * | 2007-05-21 | 2016-04-27 | 앨더바이오 홀딩스 엘엘씨 | Il-6에 대한 항체 및 이의 용도 |
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US8404235B2 (en) | 2007-05-21 | 2013-03-26 | Alderbio Holdings Llc | Antagonists of IL-6 to raise albumin and/or lower CRP |
US8062864B2 (en) | 2007-05-21 | 2011-11-22 | Alderbio Holdings Llc | Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies |
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US8252286B2 (en) * | 2007-05-21 | 2012-08-28 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
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US8178101B2 (en) | 2007-05-21 | 2012-05-15 | Alderbio Holdings Inc. | Use of anti-IL-6 antibodies having specific binding properties to treat cachexia |
US8337847B2 (en) | 2008-11-25 | 2012-12-25 | Alderbio Holdings Llc | Methods of treating anemia using anti-IL-6 antibodies |
US9212223B2 (en) | 2008-11-25 | 2015-12-15 | Alderbio Holdings Llc | Antagonists of IL-6 to prevent or treat thrombosis |
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CN108424452B (zh) * | 2011-05-20 | 2021-08-03 | H.伦德贝克公司 | 抗cgrp组合物及其用途 |
CN103911371A (zh) * | 2013-01-05 | 2014-07-09 | 中国科学院微生物研究所 | 一种酿酒酵母整合型表达载体 |
CN103911371B (zh) * | 2013-01-05 | 2016-05-04 | 中国科学院微生物研究所 | 一种酿酒酵母整合型表达载体 |
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