CN1794980A - 利用逆向热敏聚合物的暂时栓塞 - Google Patents

利用逆向热敏聚合物的暂时栓塞 Download PDF

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Publication number
CN1794980A
CN1794980A CNA2004800142986A CN200480014298A CN1794980A CN 1794980 A CN1794980 A CN 1794980A CN A2004800142986 A CNA2004800142986 A CN A2004800142986A CN 200480014298 A CN200480014298 A CN 200480014298A CN 1794980 A CN1794980 A CN 1794980A
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CN
China
Prior art keywords
inverse thermosensitive
thermosensitive polymers
poloxamer
transition temperature
polymers
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Pending
Application number
CNA2004800142986A
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English (en)
Chinese (zh)
Inventor
A·施瓦茨
J·雷蒙
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Genzyme Corp
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Biosphere Medical Inc
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Filing date
Publication date
Application filed by Biosphere Medical Inc filed Critical Biosphere Medical Inc
Priority to CN201610602830.0A priority Critical patent/CN106215226A/zh
Publication of CN1794980A publication Critical patent/CN1794980A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/765—Polymers containing oxygen
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/408—Virucides, spermicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/44—Radioisotopes, radionuclides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/442—Colorants, dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • A—HUMAN NECESSITIES
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Surgical Instruments (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
CNA2004800142986A 2003-03-24 2004-03-05 利用逆向热敏聚合物的暂时栓塞 Pending CN1794980A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610602830.0A CN106215226A (zh) 2003-03-24 2004-03-05 利用逆向热敏聚合物的暂时栓塞

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45714803P 2003-03-24 2003-03-24
US60/457,148 2003-03-24

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN2012101384368A Division CN102813967A (zh) 2003-03-24 2004-03-05 利用逆向热敏聚合物的暂时栓塞
CN201610602830.0A Division CN106215226A (zh) 2003-03-24 2004-03-05 利用逆向热敏聚合物的暂时栓塞

Publications (1)

Publication Number Publication Date
CN1794980A true CN1794980A (zh) 2006-06-28

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ID=33098204

Family Applications (3)

Application Number Title Priority Date Filing Date
CNA2004800142986A Pending CN1794980A (zh) 2003-03-24 2004-03-05 利用逆向热敏聚合物的暂时栓塞
CN201610602830.0A Pending CN106215226A (zh) 2003-03-24 2004-03-05 利用逆向热敏聚合物的暂时栓塞
CN2012101384368A Pending CN102813967A (zh) 2003-03-24 2004-03-05 利用逆向热敏聚合物的暂时栓塞

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201610602830.0A Pending CN106215226A (zh) 2003-03-24 2004-03-05 利用逆向热敏聚合物的暂时栓塞
CN2012101384368A Pending CN102813967A (zh) 2003-03-24 2004-03-05 利用逆向热敏聚合物的暂时栓塞

Country Status (11)

Country Link
US (5) US20050008610A1 (https=)
EP (2) EP1605922A4 (https=)
JP (5) JP4909071B2 (https=)
KR (2) KR101425385B1 (https=)
CN (3) CN1794980A (https=)
AU (1) AU2004224439B2 (https=)
BR (1) BRPI0408773A (https=)
CA (1) CA2519946C (https=)
HK (1) HK1197032A1 (https=)
MX (1) MXPA05010002A (https=)
WO (1) WO2004084703A2 (https=)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101677822A (zh) * 2006-12-11 2010-03-24 普拉罗美德公司 灌注器官止血法
CN102159274A (zh) * 2007-02-22 2011-08-17 普拉罗美德公司 反向热敏性聚合物在医疗程序后控制生物流体流动的用途
WO2012031457A1 (zh) * 2010-09-08 2012-03-15 上海市肿瘤研究所 用于治疗肿瘤的药物缓释血管栓塞凝胶剂及其制备方法
CN103025270A (zh) * 2010-06-07 2013-04-03 库克医药技术有限责任公司 再灌注导管系统
CN104353108A (zh) * 2014-09-29 2015-02-18 南京康玻斯医药科技有限公司 一种应用于血管吻合术及血管内闭塞术的注射剂
CN106037857A (zh) * 2008-02-29 2016-10-26 普拉罗美德公司 通过加热热敏聚合物进行的局部栓塞
CN107029277A (zh) * 2007-11-29 2017-08-11 健赞公司 使用纯化的逆向热敏聚合物的内镜粘膜切除
CN105407955B (zh) * 2013-03-15 2018-11-13 波士顿科学公司 输送药物的装置和方法

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US20040266983A1 (en) * 2000-08-17 2004-12-30 Reeve Lorraine E Purified polyoxyalkylene block copolymers
JP4909071B2 (ja) * 2003-03-24 2012-04-04 プルーローメッド， インコーポレイテッド 逆感熱性ポリマーを使用する一時的な塞栓形成
WO2005046438A2 (en) * 2003-11-06 2005-05-26 Pluromed, Inc. Internal clamp for surgical procedures
US20050228433A1 (en) * 2004-03-16 2005-10-13 Weenna Bucay-Couto In situ implant and method of forming same
US20060222596A1 (en) * 2005-04-01 2006-10-05 Trivascular, Inc. Non-degradable, low swelling, water soluble radiopaque hydrogel polymer
US20060251581A1 (en) * 2005-05-09 2006-11-09 Mcintyre Jon T Method for treatment of uterine fibroid tumors
KR101429774B1 (ko) 2005-05-09 2014-10-02 바이오스피어 메디칼 에스.에이. 마이크로스피어 및 비이온성 조영제를 사용하는 조성물 및방법
US20080031847A1 (en) * 2005-12-22 2008-02-07 Pluromed, Inc. Methods and kits for treating lacerations and puncture wounds using inverse thermosensitive polymers
US8062282B2 (en) * 2006-02-13 2011-11-22 Fossa Medical, Inc. Methods and apparatus for temporarily occluding body openings
MX2008011085A (es) * 2006-02-28 2008-09-05 Becton Dickinson Co Composiciones antimicrobianas y metodos para sellar cateteres.
EP2027729A2 (en) 2006-06-15 2009-02-25 MicroVention, Inc. Embolization device constructed from expansible polymer
US8197499B2 (en) 2006-06-21 2012-06-12 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for joining non-conjoined lumens
JP2009540965A (ja) 2006-06-21 2009-11-26 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 非結合管腔を接合するための組成物および方法
US8608760B2 (en) 2006-06-21 2013-12-17 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for joining non-conjoined lumens
EP2061547A2 (en) * 2006-09-11 2009-05-27 Pluromed, Inc. Atraumatic occlusion balloons and skirts, and methods of use thereof
WO2008112424A1 (en) * 2007-03-08 2008-09-18 Mayo Foundation For Medical Education And Research Assessing heart failure
US9987221B2 (en) * 2007-08-23 2018-06-05 Boston Scientific Scimed, Inc. Injectable hydrogel compositions
IL199781A0 (en) 2009-07-09 2010-05-17 Yohai Zorea Heat resistant probiotic compositions and healthy food comprising them
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WO2009086208A2 (en) 2007-12-21 2009-07-09 Microvention, Inc. Hydrogel filaments for biomedical uses
WO2009111172A2 (en) * 2008-02-29 2009-09-11 Pluromed, Inc. Local embolization using thermosensitive polymers
JP2011513331A (ja) * 2008-02-29 2011-04-28 アレイ バイオファーマ、インコーポレイテッド ピラゾール［３，４−ｂ］ピリジンＲＡＦ阻害剤
US8563037B2 (en) * 2009-02-06 2013-10-22 Tautona Group, L.P. Compositions and methods for joining non-conjoined lumens
US8757077B2 (en) 2009-04-30 2014-06-24 Technip France Spar mooring line sharing method and system
EP2493367B1 (en) 2009-10-26 2019-03-13 Microvention, Inc. Embolization device constructed from expansile polymer
US8840867B2 (en) 2010-05-20 2014-09-23 Val-Chum Limited Partnership Embolizing sclerosing hydrogel
US20130136826A1 (en) * 2010-08-09 2013-05-30 Degama Smart Ltd. Probiotic liquid food products
CA2820178A1 (en) 2010-12-06 2012-06-14 Degama Berrier Ltd. Composition and method for improving stability and extending shelf life of probiotic bacteria and food products thereof
WO2012145431A2 (en) 2011-04-18 2012-10-26 Microvention, Inc. Embolic devices
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