CN1771037A - 包含噻吩并[2,3－c]吡啶衍生物的药用组合物及其用途 - Google Patents

包含噻吩并[2,3－c]吡啶衍生物的药用组合物及其用途 Download PDF

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CN1771037A
CN1771037A CNA2004800093693A CN200480009369A CN1771037A CN 1771037 A CN1771037 A CN 1771037A CN A2004800093693 A CNA2004800093693 A CN A2004800093693A CN 200480009369 A CN200480009369 A CN 200480009369A CN 1771037 A CN1771037 A CN 1771037A
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Prior art keywords
pyridine
amino
benzoyl
sulfonyl
tetrahydrothieno
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CNA2004800093693A
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English (en)
Chinese (zh)
Inventor
P·格雷戈尔
N·哈里斯
J·科佩
R·朱克
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Rimonyx Pharmaceuticals Ltd
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Rimonyx Pharmaceuticals Ltd
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Publication of CN1771037A publication Critical patent/CN1771037A/zh
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
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CNA2004800093693A 2003-02-05 2004-02-05 包含噻吩并[2,3－c]吡啶衍生物的药用组合物及其用途 Pending CN1771037A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL15430603A IL154306A0 (en) 2003-02-05 2003-02-05 Pharmaceutical compositions comprising thieno [2,3-c] pyridine derivatives and use thereof
IL154306 2003-02-05

Publications (1)

Publication Number Publication Date
CN1771037A true CN1771037A (zh) 2006-05-10

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CNA2004800093693A Pending CN1771037A (zh) 2003-02-05 2004-02-05 包含噻吩并[2,3－c]吡啶衍生物的药用组合物及其用途

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US (1) US7365080B2 (enExample)
EP (1) EP1589970A4 (enExample)
JP (1) JP2006516610A (enExample)
KR (1) KR20050100655A (enExample)
CN (1) CN1771037A (enExample)
AU (1) AU2004210241A1 (enExample)
CA (1) CA2515102A1 (enExample)
IL (1) IL154306A0 (enExample)
MX (1) MXPA05008397A (enExample)
WO (1) WO2004069149A2 (enExample)

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CN104829629A (zh) * 2015-03-26 2015-08-12 天津药物研究院有限公司 含磺酰胺基的四氢噻吩并[2,3-c]吡啶衍生物、其制备方法和用途
WO2017214941A1 (zh) * 2016-06-16 2017-12-21 毛侃琅 一种提升SelP基因表达水平的慢病毒载体及其应用
CN110300596A (zh) * 2017-01-13 2019-10-01 东菱药品工业株式会社 嗜中性粒细胞活化调节剂

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ATE397000T1 (de) 2004-06-04 2008-06-15 Nycomed Gmbh Tetrahydropyridothiophenen zur verwendung in der behandlung von krebs
JP2008501768A (ja) * 2004-06-11 2008-01-24 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規の化合物及びテトラヒドロピリドチオフェンの使用
US8338648B2 (en) * 2004-06-12 2012-12-25 Signum Biosciences, Inc. Topical compositions and methods for epithelial-related conditions
EP1851229A1 (en) 2005-02-09 2007-11-07 Nycomed GmbH Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
JP2008530053A (ja) 2005-02-11 2008-08-07 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 癌の治療のための抗増殖性剤としてのテトラヒドロピリドチオフェン
EP1896484A2 (en) 2005-05-25 2008-03-12 Nycomed GmbH Tetrahydropyridothiophenes for use in the treatment of cancer
US7763728B2 (en) 2005-05-25 2010-07-27 4Sc Ag Tetrahydropyridothiophenes
WO2008020438A2 (en) * 2006-08-14 2008-02-21 Rimonyx Pharmaceuticals Ltd Benzothiazolyl thienopyridine derivatives and uses thereof
CN101821271A (zh) 2007-08-15 2010-09-01 先灵公司 可用于抑制1型11β-羟基类固醇脱氢酶的6-取代的磺酰基氮杂双环[3.2.1]辛烷类
RU2364597C1 (ru) 2007-12-14 2009-08-20 Андрей Александрович Иващенко ГЕТЕРОЦИКЛИЧЕСКИЕ ИНГИБИТОРЫ Hh-СИГНАЛЬНОГО КАСКАДА, ЛЕКАРСТВЕННЫЕ КОМПОЗИЦИИ НА ИХ ОСНОВЕ И СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ, СВЯЗАННЫХ С АББЕРАНТНОЙ АКТИВНОСТЬЮ Hh СИГНАЛЬНОЙ СИСТЕМЫ
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EA022521B1 (ru) 2010-04-28 2016-01-29 Астеллас Фарма Инк. Соединения тетрагидробензотиофена, фармацевтическая композиция на их основе, их применение и способ лечения гиперфосфатемии
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US10647725B2 (en) * 2016-04-21 2020-05-12 The University Of Toledo Anti-infective 2-aminothiophenes
ES2922932T3 (es) * 2016-12-29 2022-09-21 Enyo Pharma Derivados de tiofeno como agentes antivirales
US12459956B2 (en) 2019-09-13 2025-11-04 Alcon Inc. Heterobicyclic carboxamides and uses thereof
JP2024536926A (ja) * 2021-09-07 2024-10-08 ギズモ セラピューティクス インコーポレイテッド グリコサミノグリカンとのアミロイドペプチド相互作用の阻害剤を含む化合物及び医薬組成物、治療の方法、並びにその使用

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104829629A (zh) * 2015-03-26 2015-08-12 天津药物研究院有限公司 含磺酰胺基的四氢噻吩并[2,3-c]吡啶衍生物、其制备方法和用途
WO2017214941A1 (zh) * 2016-06-16 2017-12-21 毛侃琅 一种提升SelP基因表达水平的慢病毒载体及其应用
CN110300596A (zh) * 2017-01-13 2019-10-01 东菱药品工业株式会社 嗜中性粒细胞活化调节剂

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AU2004210241A1 (en) 2004-08-19
CA2515102A1 (en) 2004-08-19
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