CN1771037A - 包含噻吩并[2,3－c]吡啶衍生物的药用组合物及其用途 - Google Patents

包含噻吩并[2,3－c]吡啶衍生物的药用组合物及其用途 Download PDF

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Publication number
CN1771037A
CN1771037A CNA2004800093693A CN200480009369A CN1771037A CN 1771037 A CN1771037 A CN 1771037A CN A2004800093693 A CNA2004800093693 A CN A2004800093693A CN 200480009369 A CN200480009369 A CN 200480009369A CN 1771037 A CN1771037 A CN 1771037A
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Prior art keywords
pyridine
amino
benzoyl
sulfonyl
tetrahydrothieno
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Pending
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CNA2004800093693A
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English (en)
Chinese (zh)
Inventor
P·格雷戈尔
N·哈里斯
J·科佩
R·朱克
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Rimonyx Pharmaceuticals Ltd
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Rimonyx Pharmaceuticals Ltd
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Publication of CN1771037A publication Critical patent/CN1771037A/zh
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
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CNA2004800093693A 2003-02-05 2004-02-05 包含噻吩并[2,3－c]吡啶衍生物的药用组合物及其用途 Pending CN1771037A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL15430603A IL154306A0 (en) 2003-02-05 2003-02-05 Pharmaceutical compositions comprising thieno [2,3-c] pyridine derivatives and use thereof
IL154306 2003-02-05

Publications (1)

Publication Number Publication Date
CN1771037A true CN1771037A (zh) 2006-05-10

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CNA2004800093693A Pending CN1771037A (zh) 2003-02-05 2004-02-05 包含噻吩并[2,3－c]吡啶衍生物的药用组合物及其用途

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US (1) US7365080B2 (enExample)
EP (1) EP1589970A4 (enExample)
JP (1) JP2006516610A (enExample)
KR (1) KR20050100655A (enExample)
CN (1) CN1771037A (enExample)
AU (1) AU2004210241A1 (enExample)
CA (1) CA2515102A1 (enExample)
IL (1) IL154306A0 (enExample)
MX (1) MXPA05008397A (enExample)
WO (1) WO2004069149A2 (enExample)

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CN104829629A (zh) * 2015-03-26 2015-08-12 天津药物研究院有限公司 含磺酰胺基的四氢噻吩并[2,3-c]吡啶衍生物、其制备方法和用途
WO2017214941A1 (zh) * 2016-06-16 2017-12-21 毛侃琅 一种提升SelP基因表达水平的慢病毒载体及其应用
CN110300596A (zh) * 2017-01-13 2019-10-01 东菱药品工业株式会社 嗜中性粒细胞活化调节剂

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WO2005089068A2 (en) * 2004-03-24 2005-09-29 Rimonyx Pharmaceuticals Ltd. Pharmaceutical compositions comprising anti-inflammatory quinazolinecarboxamide derivatives
EP1753512B1 (en) 2004-05-28 2008-07-09 Nycomed GmbH Tetrahydropyridothiophenes
DE602005007220D1 (de) 2004-06-04 2008-07-10 Nycomed Gmbh Tetrahydropyridothiophenen zur verwendung in der behandlung von krebs
JP2008501768A (ja) * 2004-06-11 2008-01-24 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規の化合物及びテトラヒドロピリドチオフェンの使用
US8338648B2 (en) * 2004-06-12 2012-12-25 Signum Biosciences, Inc. Topical compositions and methods for epithelial-related conditions
CA2596202A1 (en) 2005-02-09 2006-08-17 Altana Pharma Ag Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
JP2008530053A (ja) 2005-02-11 2008-08-07 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 癌の治療のための抗増殖性剤としてのテトラヒドロピリドチオフェン
AU2006251167A1 (en) 2005-05-25 2006-11-30 4Sc Ag Tetrahydropyridothiophenes for use in the treatment of cancer
AU2006251169A1 (en) 2005-05-25 2006-11-30 4Sc Ag Tetrahydropyridothiophenes for use in the treatment of cancer
US20100298370A1 (en) * 2006-03-20 2010-11-25 Paul Gregor Benzothiazolyl thienopyridine derivatives and uses thereof
US8466149B2 (en) 2007-08-15 2013-06-18 Merck Sharp & Dohme Corp. 6-substituted sulfonyl azabicyclo[3.2.1]octanes useful to inhibit 11β-hydroxysteroid dehydrogenase type-I
RU2364597C1 (ru) * 2007-12-14 2009-08-20 Андрей Александрович Иващенко ГЕТЕРОЦИКЛИЧЕСКИЕ ИНГИБИТОРЫ Hh-СИГНАЛЬНОГО КАСКАДА, ЛЕКАРСТВЕННЫЕ КОМПОЗИЦИИ НА ИХ ОСНОВЕ И СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ, СВЯЗАННЫХ С АББЕРАНТНОЙ АКТИВНОСТЬЮ Hh СИГНАЛЬНОЙ СИСТЕМЫ
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ES2761295T3 (es) 2009-03-02 2020-05-19 Stemsynergy Therapeutics Inc Métodos y composiciones para su uso en el tratamiento del cáncer y para reducir los efectos mediados por Wnt en una célula
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WO2012148889A1 (en) * 2011-04-28 2012-11-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Inhibitors of human apurinic/apyrimidinic endonuclease 1
US8889159B2 (en) 2011-11-29 2014-11-18 Gilead Pharmasset Llc Compositions and methods for treating hepatitis C virus
SG11201402609RA (en) * 2011-11-29 2014-06-27 Gilead Pharmasset Llc Compositions and methods for treating hepatitis c virus
WO2016197078A1 (en) * 2015-06-05 2016-12-08 Syros Pharmaceuticals, Inc. Compounds for the modulation of myc activity
US10106290B2 (en) 2015-12-14 2018-10-23 Westrock Shared Services, Llc Carton, blank, and method of folding
US10647725B2 (en) * 2016-04-21 2020-05-12 The University Of Toledo Anti-infective 2-aminothiophenes
KR20190098204A (ko) 2016-12-29 2019-08-21 엔요 파마 항바이러스제로서의 티오펜 유도체
WO2021050994A1 (en) * 2019-09-13 2021-03-18 Aerie Pharmaceuticals, Inc. Heterobicyclic carboxamides and uses thereof
AU2022341967A1 (en) * 2021-09-07 2024-05-16 Gismo Therapeutics, Inc. Compounds and pharmaceutical compositions comprising inhibitors of amyloid peptide interactions with glycosaminoglycans, methods of treatment, and use thereof

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US6232320B1 (en) * 1998-06-04 2001-05-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
HK1045306A1 (zh) * 1999-06-03 2002-11-22 Abbott Laboratories 抑制细胞黏附的抗炎化合物
JP4548882B2 (ja) * 1999-11-30 2010-09-22 興和創薬株式会社 ４，５，６，７−テトラヒドロチエノ〔２，３−ｃ〕ピリジン化合物

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104829629A (zh) * 2015-03-26 2015-08-12 天津药物研究院有限公司 含磺酰胺基的四氢噻吩并[2,3-c]吡啶衍生物、其制备方法和用途
WO2017214941A1 (zh) * 2016-06-16 2017-12-21 毛侃琅 一种提升SelP基因表达水平的慢病毒载体及其应用
CN110300596A (zh) * 2017-01-13 2019-10-01 东菱药品工业株式会社 嗜中性粒细胞活化调节剂

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EP1589970A2 (en) 2005-11-02
KR20050100655A (ko) 2005-10-19
US7365080B2 (en) 2008-04-29
MXPA05008397A (es) 2006-02-17
US20060135529A1 (en) 2006-06-22
EP1589970A4 (en) 2008-05-21
WO2004069149A2 (en) 2004-08-19
AU2004210241A1 (en) 2004-08-19
WO2004069149A3 (en) 2004-11-25
IL154306A0 (en) 2003-09-17
JP2006516610A (ja) 2006-07-06
CA2515102A1 (en) 2004-08-19

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