CN1745847A - 用精氨酸酶治疗肝炎的药物组合物和方法 - Google Patents
用精氨酸酶治疗肝炎的药物组合物和方法 Download PDFInfo
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- CN1745847A CN1745847A CNA2004100768544A CN200410076854A CN1745847A CN 1745847 A CN1745847 A CN 1745847A CN A2004100768544 A CNA2004100768544 A CN A2004100768544A CN 200410076854 A CN200410076854 A CN 200410076854A CN 1745847 A CN1745847 A CN 1745847A
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- arginase
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- A61K38/46—Hydrolases (3)
- A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- Health & Medical Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2004100768544A CN1745847A (zh) | 2004-09-08 | 2004-09-08 | 用精氨酸酶治疗肝炎的药物组合物和方法 |
| EP05783950A EP1803465A4 (en) | 2004-09-08 | 2005-09-06 | PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATING HEPATITIS WITH ARGINASES |
| JP2007530572A JP2008512399A (ja) | 2004-09-08 | 2005-09-06 | 医薬組成物およびアルギナーゼを用いる肝炎の処置方法 |
| KR1020077007829A KR20070100875A (ko) | 2004-09-08 | 2005-09-06 | 약학 조성물 및 아르기나제로 간염을 치료하는 방법 |
| PCT/CN2005/001411 WO2006026915A1 (fr) | 2004-09-08 | 2005-09-06 | Composition pharmaceutique et methode de traitement de l'hepatite avec des arginases |
| US11/680,631 US20080299638A1 (en) | 2004-09-08 | 2007-03-01 | Pharmaceutical Composition and Method of Treating Hepatitis with Arginases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2004100768544A CN1745847A (zh) | 2004-09-08 | 2004-09-08 | 用精氨酸酶治疗肝炎的药物组合物和方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1745847A true CN1745847A (zh) | 2006-03-15 |
Family
ID=36036072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2004100768544A Pending CN1745847A (zh) | 2004-09-08 | 2004-09-08 | 用精氨酸酶治疗肝炎的药物组合物和方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20080299638A1 (https=) |
| EP (1) | EP1803465A4 (https=) |
| JP (1) | JP2008512399A (https=) |
| KR (1) | KR20070100875A (https=) |
| CN (1) | CN1745847A (https=) |
| WO (1) | WO2006026915A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103184209A (zh) * | 2011-12-27 | 2013-07-03 | 拜奥生物科技（上海）有限公司 | 人精氨酸酶和聚乙二醇化人精氨酸酶及其应用 |
| CN106456723A (zh) * | 2014-04-29 | 2017-02-22 | 康达医药科技有限公司 | 采用精氨酸酶i调节免疫系统的方法和组合物 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2742497C (en) * | 2008-10-31 | 2024-01-23 | George Georgiou | Compositions of engineered human arginases and methods for treating cancer |
| AU2010242422B2 (en) * | 2009-03-26 | 2014-12-04 | The Hong Kong Polytechnic University | Site-directed pegylation of arginases and the use thereof as anti-cancer and anti-viral agents |
| GB2568000A (en) | 2016-08-08 | 2019-05-01 | Aerase Inc | Compositions and methods for treating cancer with arginine depletion and immuno oncology agents |
| CN120661640A (zh) | 2017-12-05 | 2025-09-19 | 伊梅尔迪卡制药公司 | 用于治疗精氨酸酶1缺乏症的方法和组合物 |
| WO2020081994A1 (en) | 2018-10-19 | 2020-04-23 | Aerase, Inc. | Arginine depletion therapy for treatment of gamt deficiency |
| KR20220082813A (ko) | 2019-08-30 | 2022-06-17 | 아이글레아 바이오테라퓨틱스, 인크. | 인간 재조합 아르기나아제 1의 제조 방법 및 이의 사용 |
| JP2023522888A (ja) * | 2020-04-17 | 2023-06-01 | バイオ－キャンサー・トリートメント・インターナショナル・リミテッド | アルギナーゼを使用してウイルス感染症を処置する方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1059127C (zh) * | 1995-07-19 | 2000-12-06 | 郝文学 | 治疗肝病的药物“疏肝酶”的制法 |
| US5780286A (en) * | 1996-03-14 | 1998-07-14 | Smithkline Beecham Corporation | Arginase II |
| US5851985A (en) * | 1996-08-16 | 1998-12-22 | Tepic; Slobodan | Treatment of tumors by arginine deprivation |
| US6183738B1 (en) * | 1997-05-12 | 2001-02-06 | Phoenix Pharamacologics, Inc. | Modified arginine deiminase |
| JP2005538709A (ja) * | 2002-06-20 | 2005-12-22 | バイオ−キャンサー・トリートメント・インターナショナル・リミテッド | アルギニンを欠乏させることによってヒト悪性腫瘍を治療する医薬品及び方法 |
| HK1053577A2 (en) * | 2002-06-20 | 2003-10-10 | Bio-Cancer Treatment International Limited | Pharmaceutical composition and method of treatment of human malignanices with arginine deprivation |
-
2004
- 2004-09-08 CN CNA2004100768544A patent/CN1745847A/zh active Pending
-
2005
- 2005-09-06 EP EP05783950A patent/EP1803465A4/en not_active Withdrawn
- 2005-09-06 WO PCT/CN2005/001411 patent/WO2006026915A1/zh not_active Ceased
- 2005-09-06 JP JP2007530572A patent/JP2008512399A/ja active Pending
- 2005-09-06 KR KR1020077007829A patent/KR20070100875A/ko not_active Withdrawn
-
2007
- 2007-03-01 US US11/680,631 patent/US20080299638A1/en not_active Abandoned
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103184209A (zh) * | 2011-12-27 | 2013-07-03 | 拜奥生物科技（上海）有限公司 | 人精氨酸酶和聚乙二醇化人精氨酸酶及其应用 |
| WO2013097657A1 (zh) * | 2011-12-27 | 2013-07-04 | 拜奥生物科技（上海）有限公司 | 人精氨酸酶和定点聚乙二醇化人精氨酸酶及其应用 |
| US9109218B2 (en) | 2011-12-27 | 2015-08-18 | Bio-Cancer Treatment International Ltd. (Shanghai) | Human arginase and pegylated human arginase and the use thereof |
| CN103184209B (zh) * | 2011-12-27 | 2015-09-16 | 拜奥生物科技（上海）有限公司 | 人精氨酸酶和聚乙二醇化人精氨酸酶及其应用 |
| CN106456723A (zh) * | 2014-04-29 | 2017-02-22 | 康达医药科技有限公司 | 采用精氨酸酶i调节免疫系统的方法和组合物 |
| US10532086B2 (en) | 2014-04-29 | 2020-01-14 | Bio-Cancer Treatment International Limited | Methods and compositions for modulating the immune system with arginase I |
| CN106456723B (zh) * | 2014-04-29 | 2021-03-09 | 康达医药科技有限公司 | 采用精氨酸酶i调节免疫系统的方法和组合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1803465A4 (en) | 2009-08-12 |
| JP2008512399A (ja) | 2008-04-24 |
| KR20070100875A (ko) | 2007-10-12 |
| WO2006026915A1 (fr) | 2006-03-16 |
| EP1803465A1 (en) | 2007-07-04 |
| US20080299638A1 (en) | 2008-12-04 |
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