JP2008512399A - 医薬組成物およびアルギナーゼを用いる肝炎の処置方法 - Google Patents

医薬組成物およびアルギナーゼを用いる肝炎の処置方法 Download PDF

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JP2008512399A
JP2008512399A JP2007530572A JP2007530572A JP2008512399A JP 2008512399 A JP2008512399 A JP 2008512399A JP 2007530572 A JP2007530572 A JP 2007530572A JP 2007530572 A JP2007530572 A JP 2007530572A JP 2008512399 A JP2008512399 A JP 2008512399A
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arginase
pharmaceutical composition
enzyme
composition according
use according
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JP2007530572A
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Japanese (ja)
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JP2008512399A5 (https=
Inventor
寧 民 鄭
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康達医藥科技有限公司
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Publication of JP2008512399A5 publication Critical patent/JP2008512399A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/50Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2007530572A 2004-09-08 2005-09-06 医薬組成物およびアルギナーゼを用いる肝炎の処置方法 Pending JP2008512399A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNA2004100768544A CN1745847A (zh) 2004-09-08 2004-09-08 用精氨酸酶治疗肝炎的药物组合物和方法
PCT/CN2005/001411 WO2006026915A1 (fr) 2004-09-08 2005-09-06 Composition pharmaceutique et methode de traitement de l'hepatite avec des arginases

Publications (2)

Publication Number Publication Date
JP2008512399A true JP2008512399A (ja) 2008-04-24
JP2008512399A5 JP2008512399A5 (https=) 2008-10-02

Family

ID=36036072

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007530572A Pending JP2008512399A (ja) 2004-09-08 2005-09-06 医薬組成物およびアルギナーゼを用いる肝炎の処置方法

Country Status (6)

Country Link
US (1) US20080299638A1 (https=)
EP (1) EP1803465A4 (https=)
JP (1) JP2008512399A (https=)
KR (1) KR20070100875A (https=)
CN (1) CN1745847A (https=)
WO (1) WO2006026915A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3778885T (pt) * 2008-10-31 2023-05-31 Aerase Inc Composições de arginases humanas modificadas e métodos para o tratamento do cancro
CA2756442C (en) 2009-03-26 2016-03-29 The Hong Kong Polytechnic University Site-directed pegylation of arginases and the use thereof as anti-cancer and anti-viral agents
CN103184209B (zh) * 2011-12-27 2015-09-16 拜奥生物科技(上海)有限公司 人精氨酸酶和聚乙二醇化人精氨酸酶及其应用
ES2897635T3 (es) * 2014-04-29 2022-03-02 Bio Cancer Treat International Ltd Métodos y composiciones para modular el sistema inmunológico con la arginasa I
GB2568000A (en) 2016-08-08 2019-05-01 Aerase Inc Compositions and methods for treating cancer with arginine depletion and immuno oncology agents
US11717562B2 (en) 2017-12-05 2023-08-08 Aerase, Inc. Method and composition for treating arginase 1 deficiency
CA3116736A1 (en) 2018-10-19 2020-04-23 Aerase, Inc. Arginine depletion therapy for treatment of gamt deficiency
CN114729344A (zh) 2019-08-30 2022-07-08 安格利亚生物制药公司 人重组精氨酸酶1的生产方法及其用途
CA3180529A1 (en) * 2020-04-17 2021-10-21 Bio-Cancer Treatment International Limited Methods of treating viral infections using arginase

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004001048A1 (en) * 2002-06-20 2003-12-31 Bio-Cancer Treatment International Limited Pharmaceutical composition and method of treatment of human malignancies with arginine deprivation
WO2004000349A1 (en) * 2002-06-20 2003-12-31 Bio-Cancer Treatment International Limited Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1059127C (zh) * 1995-07-19 2000-12-06 郝文学 治疗肝病的药物“疏肝酶”的制法
US5780286A (en) * 1996-03-14 1998-07-14 Smithkline Beecham Corporation Arginase II
US5851985A (en) * 1996-08-16 1998-12-22 Tepic; Slobodan Treatment of tumors by arginine deprivation
US6183738B1 (en) * 1997-05-12 2001-02-06 Phoenix Pharamacologics, Inc. Modified arginine deiminase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004001048A1 (en) * 2002-06-20 2003-12-31 Bio-Cancer Treatment International Limited Pharmaceutical composition and method of treatment of human malignancies with arginine deprivation
WO2004000349A1 (en) * 2002-06-20 2003-12-31 Bio-Cancer Treatment International Limited Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation

Also Published As

Publication number Publication date
CN1745847A (zh) 2006-03-15
EP1803465A1 (en) 2007-07-04
EP1803465A4 (en) 2009-08-12
KR20070100875A (ko) 2007-10-12
WO2006026915A1 (fr) 2006-03-16
US20080299638A1 (en) 2008-12-04

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