CN1720227A - N－芳基磺酰基－3－氨基烷氧基吲哚 - Google Patents

N－芳基磺酰基－3－氨基烷氧基吲哚 Download PDF

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Publication number
CN1720227A
CN1720227A CNA2003801046430A CN200380104643A CN1720227A CN 1720227 A CN1720227 A CN 1720227A CN A2003801046430 A CNA2003801046430 A CN A2003801046430A CN 200380104643 A CN200380104643 A CN 200380104643A CN 1720227 A CN1720227 A CN 1720227A
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Prior art keywords
ethyl
dimethylamine
oxygen
indol
bromo
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Pending
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Chinese (zh)
Inventor
文卡塔·萨蒂亚·尼罗齐·罗摩克里希纳
弗尔卡斯·什里克瑞什那·希尔萨斯
拉玛·萨斯特里·甘朴汉帕蒂
文卡塔·萨蒂亚·维拉哈德劳·瓦德莱姆蒂·拉奥
文卡特斯瓦卢·贾斯提
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Suven Life Sciences Ltd
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Suven Life Sciences Ltd
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Publication of CN1720227A publication Critical patent/CN1720227A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Reproductive Health (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
CNA2003801046430A 2002-11-28 2003-11-25 N－芳基磺酰基－3－氨基烷氧基吲哚 Pending CN1720227A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN883/MAS/2002 2002-11-28
IN883MA2002 2002-11-28

Related Child Applications (1)

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CN2011101270926A Division CN102249981A (zh) 2002-11-28 2003-11-25 N-芳基磺酰基-3-氨基烷氧基吲哚

Publications (1)

Publication Number Publication Date
CN1720227A true CN1720227A (zh) 2006-01-11

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CNA2003801046430A Pending CN1720227A (zh) 2002-11-28 2003-11-25 N－芳基磺酰基－3－氨基烷氧基吲哚
CN2011101270926A Pending CN102249981A (zh) 2002-11-28 2003-11-25 N-芳基磺酰基-3-氨基烷氧基吲哚

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US (2) US7507835B2 (https=)
EP (1) EP1567492B1 (https=)
JP (2) JP4782425B2 (https=)
KR (1) KR100776118B1 (https=)
CN (2) CN1720227A (https=)
AU (1) AU2003285759B2 (https=)
BR (1) BRPI0315958B8 (https=)
CA (1) CA2507505C (https=)
CY (1) CY1114241T1 (https=)
EA (1) EA009193B1 (https=)
ES (1) ES2425143T3 (https=)
MX (1) MXPA05005700A (https=)
NO (1) NO331805B1 (https=)
NZ (1) NZ540842A (https=)
PT (1) PT1567492E (https=)
SI (1) SI1567492T1 (https=)
WO (1) WO2004048328A2 (https=)
ZA (1) ZA200504044B (https=)

Cited By (2)

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CN101675032B (zh) * 2007-05-03 2012-10-31 苏文生命科学有限公司 氨基烷氧基芳基磺酰胺化合物及其作为5-ht6配体的用途
CN101835748B (zh) * 2007-10-26 2012-11-14 苏文生命科学有限公司 氨基芳基磺胺化合物及其作为5-ht6配体的用途

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EP2346847B1 (en) 2008-09-17 2013-05-15 Suven Life Sciences Limited Aryl sulfonamide amine compounds and their use as 5-ht6 ligands
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CA2786072C (en) 2010-01-05 2014-10-28 Suven Life Sciences Limited Sulfone compounds as 5-ht6 receptor ligands
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101675032B (zh) * 2007-05-03 2012-10-31 苏文生命科学有限公司 氨基烷氧基芳基磺酰胺化合物及其作为5-ht6配体的用途
CN101835748B (zh) * 2007-10-26 2012-11-14 苏文生命科学有限公司 氨基芳基磺胺化合物及其作为5-ht6配体的用途

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BR0315958A (pt) 2005-09-13
BRPI0315958B8 (pt) 2021-05-25
CY1114241T1 (el) 2016-08-31
AU2003285759A1 (en) 2004-06-18
JP2006511506A (ja) 2006-04-06
US7718690B2 (en) 2010-05-18
US7507835B2 (en) 2009-03-24
PT1567492E (pt) 2013-07-22
NZ540842A (en) 2008-05-30
CA2507505A1 (en) 2004-06-10
EP1567492A2 (en) 2005-08-31
WO2004048328A2 (en) 2004-06-10
KR100776118B1 (ko) 2007-11-15
EA200500882A1 (ru) 2005-12-29
MXPA05005700A (es) 2005-08-16
WO2004048328A3 (en) 2004-10-28
NO20052825D0 (no) 2005-06-10
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BRPI0315958B1 (pt) 2018-06-26
NO20052825L (no) 2005-08-25
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JP4782425B2 (ja) 2011-09-28
CN102249981A (zh) 2011-11-23
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US20060173193A1 (en) 2006-08-03
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