CN1620461A - 2－氨基－丙醇衍生物 - Google Patents

2－氨基－丙醇衍生物 Download PDF

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Publication number
CN1620461A
CN1620461A CNA028068378A CN02806837A CN1620461A CN 1620461 A CN1620461 A CN 1620461A CN A028068378 A CNA028068378 A CN A028068378A CN 02806837 A CN02806837 A CN 02806837A CN 1620461 A CN1620461 A CN 1620461A
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China
Prior art keywords
phenyl
alkyl
amino
compound
optional
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Pending
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CNA028068378A
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English (en)
Chinese (zh)
Inventor
R·阿尔贝特
T·鲍姆鲁克尔
V·布林克曼
S·科滕斯
C·帕帕耶奥尔尤
E·E·普里施尔－斯特拉斯马尔
K·欣特尔丁
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Novartis AG
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Novartis AG
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Priority claimed from GB0107506A external-priority patent/GB0107506D0/en
Priority claimed from GB0107507A external-priority patent/GB0107507D0/en
Priority claimed from GB0108346A external-priority patent/GB0108346D0/en
Application filed by Novartis AG filed Critical Novartis AG
Publication of CN1620461A publication Critical patent/CN1620461A/zh
Pending legal-status Critical Current

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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
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    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
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    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
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    • C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
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    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
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    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
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    • C07C2601/00—Systems containing only non-condensed rings
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    • C07C2601/14—The ring being saturated

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
CNA028068378A 2001-03-26 2002-03-26 2－氨基－丙醇衍生物 Pending CN1620461A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB0107506A GB0107506D0 (en) 2001-03-26 2001-03-26 Organic compounds
GB0107507.6 2001-03-26
GB0107507A GB0107507D0 (en) 2001-03-26 2001-03-26 Organic compounds
GB0107506.8 2001-03-26
GB0108346.8 2001-04-03
GB0108346A GB0108346D0 (en) 2001-04-03 2001-04-03 Organic compounds

Publications (1)

Publication Number Publication Date
CN1620461A true CN1620461A (zh) 2005-05-25

Family

ID=27256123

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028068378A Pending CN1620461A (zh) 2001-03-26 2002-03-26 2－氨基－丙醇衍生物

Country Status (18)

Country Link
US (1) US7326801B2 (enExample)
EP (1) EP1377593B1 (enExample)
JP (1) JP4012823B2 (enExample)
KR (1) KR20030093279A (enExample)
CN (1) CN1620461A (enExample)
AT (1) ATE314383T1 (enExample)
BR (1) BR0208365A (enExample)
CA (1) CA2442178A1 (enExample)
CZ (1) CZ20032560A3 (enExample)
DE (1) DE60208355T2 (enExample)
DK (1) DK1377593T3 (enExample)
ES (1) ES2254675T3 (enExample)
IL (1) IL157773A0 (enExample)
MX (1) MXPA03008755A (enExample)
NO (1) NO20034291L (enExample)
PL (1) PL367348A1 (enExample)
SK (1) SK11942003A3 (enExample)
WO (1) WO2002076995A2 (enExample)

Families Citing this family (49)

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ATE435202T1 (de) 2002-01-11 2009-07-15 Daiichi Sankyo Co Ltd Aminoalkoholderivat oder phosphonsäurederivat und diese enthaltende medizinische zusammensetzung
ATE412408T1 (de) 2002-05-16 2008-11-15 Novartis Pharma Gmbh Verwendung von edg rezeptor bindenden wirkstoffen für die krebstherapie
RU2358717C2 (ru) * 2002-05-16 2009-06-20 Новартис Аг Применение средств, связывающих edg-рецептор, в лечении ракового заболевания
GB0217152D0 (en) * 2002-07-24 2002-09-04 Novartis Ag Organic compounds
WO2004010949A2 (en) 2002-07-30 2004-02-05 University Of Virginia Patent Foundation Compounds active in spinigosine 1-phosphate signaling
AU2003273865A1 (en) 2002-09-13 2004-04-30 Novartis Ag Amino-propanol derivatives
CA2498944C (en) 2002-09-19 2011-05-17 Yasushi Kohno Amino alcohol derivatives, salts thereof and immunosuppressive agents
KR20080103117A (ko) * 2002-09-24 2008-11-26 노파르티스 아게 탈수초성 장애의 치료에 있어서의 스핑고신-1-포스페이트 수용체 아고니스트
EP1594508B1 (en) * 2003-02-11 2012-08-08 Irm Llc Novel bicyclic compounds and compositions
SI1602660T1 (sl) * 2003-02-18 2011-06-30 Kyorin Seiyaku Kk Derivati aminofosfonske kisline, njihove adicijske soli in modulatorji receptorja za S1P
DE102004016947A1 (de) 2003-04-08 2004-10-21 Novartis Ag Feste pharmazeutische Zusammensetzung
ES2392167T3 (es) 2003-04-30 2012-12-05 Novartis Ag Derivados aminopropanol como moduladores del receptor esfingosina-1-fosfato
ATE547395T1 (de) 2003-04-30 2012-03-15 Novartis Pharma Gmbh Aminopropanol-derivate als modulatoren des sphingosin-1-phosphat-rezeptors
GB0313612D0 (en) * 2003-06-12 2003-07-16 Novartis Ag Organic compounds
US7528120B2 (en) * 2003-08-28 2009-05-05 Novartis Ag Aminopropanol derivatives
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
WO2005041899A2 (en) 2003-11-03 2005-05-12 University Of Virginia Patent Foundation Orally available sphingosine 1-phosphate receptor agonists and antagonists
JPWO2005044780A1 (ja) * 2003-11-10 2007-05-17 杏林製薬株式会社 アミノカルボン酸誘導体とその付加塩及びｓ１ｐ受容体調節剤
GB0329498D0 (en) * 2003-12-19 2004-01-28 Novartis Ag Organic compounds
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GB0411929D0 (en) * 2004-05-27 2004-06-30 Novartis Ag Organic compounds
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BR0208365A (pt) 2004-03-09
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