CN1575177A - Cxcr3拮抗剂 - Google Patents

Cxcr3拮抗剂 Download PDF

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Publication number
CN1575177A
CN1575177A CNA018225969A CN01822596A CN1575177A CN 1575177 A CN1575177 A CN 1575177A CN A018225969 A CNA018225969 A CN A018225969A CN 01822596 A CN01822596 A CN 01822596A CN 1575177 A CN1575177 A CN 1575177A
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Prior art keywords
alkyl
heteroaryl
aryl
chemical compound
unsubstituted
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CNA018225969A
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Chinese (zh)
Inventor
J·C·梅迪纳
M·G·约翰森
A·-R·李
J·刘
A·X·黄
L·朱
A·P·马库斯
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Amgen Inc
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Tularik Inc
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Publication of CN1575177A publication Critical patent/CN1575177A/zh
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  • Organic Chemistry (AREA)
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  • Dermatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
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  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA018225969A 2000-12-11 2001-12-11 Cxcr3拮抗剂 Pending CN1575177A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25524100P 2000-12-11 2000-12-11
US60/255,241 2000-12-11
US29649901P 2001-06-06 2001-06-06
US60/296,499 2001-06-06

Publications (1)

Publication Number Publication Date
CN1575177A true CN1575177A (zh) 2005-02-02

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CNA018225969A Pending CN1575177A (zh) 2000-12-11 2001-12-11 Cxcr3拮抗剂

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US (3) US6964967B2 (enExample)
EP (1) EP1343505A1 (enExample)
JP (1) JP4259877B2 (enExample)
KR (1) KR100883184B1 (enExample)
CN (1) CN1575177A (enExample)
AU (1) AU2001297717B2 (enExample)
BR (1) BR0116096A (enExample)
CA (1) CA2431553A1 (enExample)
CZ (1) CZ20031910A3 (enExample)
EA (1) EA007538B1 (enExample)
HU (1) HUP0500880A2 (enExample)
IL (2) IL156304A0 (enExample)
MX (1) MXPA03005152A (enExample)
NO (1) NO325450B1 (enExample)
NZ (1) NZ526622A (enExample)
PL (1) PL366311A1 (enExample)
SK (1) SK8752003A3 (enExample)
WO (1) WO2002083143A1 (enExample)
ZA (1) ZA200304342B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103796693A (zh) * 2011-06-13 2014-05-14 Ith免疫治疗控股股份公司 治疗与代谢综合征相关的病症
CN101796073B (zh) * 2007-02-01 2014-08-13 特瓦生物制药美国有限公司 针对cxcr3的人源化抗体
CN108794496A (zh) * 2018-04-28 2018-11-13 北京施安泰医药技术开发有限公司 一类cdk抑制剂、其药物组合物、制备方法及用途

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US7671200B2 (en) 1999-10-27 2010-03-02 Cytokinetics, Inc. Quinazolinone KSP inhibitors
US7230000B1 (en) * 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
AU2001297717B2 (en) * 2000-12-11 2006-02-23 Amgen Inc. CXCR3 antagonists
US6794379B2 (en) * 2001-06-06 2004-09-21 Tularik Inc. CXCR3 antagonists
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
RU2325387C2 (ru) 2001-12-21 2008-05-27 Анормед Инк. Гетероциклические соединения с повышенной эффективностью, связывающиеся с рецептором хемокина
US7354932B2 (en) * 2001-12-21 2008-04-08 Anormed, Inc. Chemokine receptor binding heterocyclic compounds with enhanced efficacy
JP5082033B2 (ja) 2001-12-21 2012-11-28 エグゼリクシス パテント カンパニー エルエルシー Ｌｘｒのモジュレーター
JP2005529076A (ja) * 2002-02-15 2005-09-29 サイトキネティクス・インコーポレーテッド キナゾリノンの合成
ATE507210T1 (de) * 2002-03-07 2011-05-15 X Ceptor Therapeutics Inc Chinazolinon modulatoren von nukleinrezeptoren
WO2003084544A2 (en) * 2002-04-04 2003-10-16 Cv Therapeutics, Inc. Compounds dor increasing abca-1 expression useful for treating coronary artery disease and atherosclerosis
CN100381437C (zh) * 2002-04-17 2008-04-16 赛特凯恩蒂克公司 化合物、组合物和方法
US7214800B2 (en) * 2002-05-09 2007-05-08 Cytokinetics, Inc. Compounds, compositions, and methods
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CN103796693A (zh) * 2011-06-13 2014-05-14 Ith免疫治疗控股股份公司 治疗与代谢综合征相关的病症
CN103796693B (zh) * 2011-06-13 2017-05-31 Ith免疫治疗控股股份公司 治疗与代谢综合征相关的病症
CN108794496A (zh) * 2018-04-28 2018-11-13 北京施安泰医药技术开发有限公司 一类cdk抑制剂、其药物组合物、制备方法及用途
CN108794496B (zh) * 2018-04-28 2020-04-24 北京施安泰医药技术开发有限公司 一类cdk抑制剂、其药物组合物、制备方法及用途

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JP2004536796A (ja) 2004-12-09
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US20020169159A1 (en) 2002-11-14
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