CN1416335B - 新的自乳化药物释放体系 - Google Patents

新的自乳化药物释放体系 Download PDF

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Publication number
CN1416335B
CN1416335B CN018061613A CN01806161A CN1416335B CN 1416335 B CN1416335 B CN 1416335B CN 018061613 A CN018061613 A CN 018061613A CN 01806161 A CN01806161 A CN 01806161A CN 1416335 B CN1416335 B CN 1416335B
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CN
China
Prior art keywords
pharmaceutical composition
nsaid
capsule
preparation
surfactant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN018061613A
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English (en)
Chinese (zh)
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CN1416335A (zh
Inventor
C·霍姆贝里
B·西克曼
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Nicox SA
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Nicox SA
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Publication of CN1416335A publication Critical patent/CN1416335A/zh
Application granted granted Critical
Publication of CN1416335B publication Critical patent/CN1416335B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CN018061613A 2000-03-08 2001-03-06 新的自乳化药物释放体系 Expired - Fee Related CN1416335B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE0000773-2 2000-03-08
SE00007732 2000-03-08
SE0000773A SE0000773D0 (sv) 2000-03-08 2000-03-08 New formulation
PCT/SE2001/000467 WO2001066088A1 (en) 2000-03-08 2001-03-06 New self emulsifying drug delivery system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201010156308A Division CN101862453A (zh) 2000-03-08 2001-03-06 新的自乳化药物释放体系

Publications (2)

Publication Number Publication Date
CN1416335A CN1416335A (zh) 2003-05-07
CN1416335B true CN1416335B (zh) 2010-04-28

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
CN201010156308A Pending CN101862453A (zh) 2000-03-08 2001-03-06 新的自乳化药物释放体系
CN018061613A Expired - Fee Related CN1416335B (zh) 2000-03-08 2001-03-06 新的自乳化药物释放体系

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201010156308A Pending CN101862453A (zh) 2000-03-08 2001-03-06 新的自乳化药物释放体系

Country Status (31)

Country Link
US (1) US20030161846A1 ( )
EP (1) EP1267832B1 ( )
JP (1) JP4663197B2 ( )
KR (1) KR100771317B1 ( )
CN (2) CN101862453A ( )
AT (1) ATE268162T1 ( )
AU (2) AU3787601A ( )
BR (1) BR0109014A ( )
CA (1) CA2401498C ( )
CZ (1) CZ20023005A3 ( )
DE (1) DE60103627T2 ( )
DK (1) DK1267832T3 ( )
EE (1) EE200200500A ( )
ES (1) ES2220728T3 ( )
HK (1) HK1050632A1 ( )
HU (1) HUP0300882A3 ( )
IL (1) IL151427A0 ( )
IS (1) IS6539A ( )
MX (1) MXPA02008657A ( )
MY (1) MY127237A ( )
NO (1) NO20024272L ( )
NZ (1) NZ521009A ( )
PL (1) PL202683B1 ( )
PT (1) PT1267832E ( )
RU (1) RU2270675C9 ( )
SE (1) SE0000773D0 ( )
SK (1) SK285982B6 ( )
TR (1) TR200401906T4 ( )
UA (1) UA82979C2 ( )
WO (1) WO2001066088A1 ( )
ZA (1) ZA200206740B ( )

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WO2016117057A1 (ja) * 2015-01-21 2016-07-28 持田製薬株式会社 ω３脂肪酸の自己乳化組成物
JP6989489B2 (ja) * 2015-08-07 2022-01-05 インファースト ヘルスケア リミテッド Ｎｓａｉｄのための固溶体組成物
CN113440481B (zh) * 2021-08-13 2022-06-14 湖南慧泽生物医药科技有限公司 伊布替尼的自微乳组合物

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NZ521009A (en) 2004-06-25
JP2003525894A (ja) 2003-09-02
HK1050632A1 (en) 2003-07-04
KR20030011787A (ko) 2003-02-11
NO20024272D0 (no) 2002-09-06
JP4663197B2 (ja) 2011-03-30
RU2270675C2 (ru) 2006-02-27
RU2270675C9 (ru) 2006-06-27
AU3787601A (en) 2001-09-17
US20030161846A1 (en) 2003-08-28
EP1267832A1 (en) 2003-01-02
UA82979C2 (ru) 2008-06-10
PL202683B1 (pl) 2009-07-31
WO2001066088A1 (en) 2001-09-13
SK285982B6 (sk) 2007-12-06
CA2401498C (en) 2010-05-18
DE60103627D1 (de) 2004-07-08
HUP0300882A2 (hu) 2003-09-29
SE0000773D0 (sv) 2000-03-08
ZA200206740B (en) 2003-11-24
BR0109014A (pt) 2003-06-03
EE200200500A (et) 2004-02-16
IS6539A (is) 2002-09-03
HUP0300882A3 (en) 2005-04-28
CN101862453A (zh) 2010-10-20
IL151427A0 (en) 2003-04-10
RU2002122744A (ru) 2004-03-20
PL358595A1 (en) 2004-08-09
MY127237A (en) 2006-11-30
CN1416335A (zh) 2003-05-07
ATE268162T1 (de) 2004-06-15
ES2220728T3 (es) 2004-12-16
DK1267832T3 (da) 2004-08-30
DE60103627T2 (de) 2005-06-16
NO20024272L (no) 2002-11-05
SK12572002A3 (sk) 2003-05-02
PT1267832E (pt) 2004-09-30
CZ20023005A3 (cs) 2003-02-12
AU2001237876B2 (en) 2005-02-17
TR200401906T4 (tr) 2004-09-21
MXPA02008657A (es) 2003-02-24
EP1267832B1 (en) 2004-06-02
CA2401498A1 (en) 2001-09-13
KR100771317B1 (ko) 2007-10-29

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