CN1399542A - 药用载体制剂 - Google Patents
药用载体制剂 Download PDFInfo
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- CN1399542A CN1399542A CN00816307A CN00816307A CN1399542A CN 1399542 A CN1399542 A CN 1399542A CN 00816307 A CN00816307 A CN 00816307A CN 00816307 A CN00816307 A CN 00816307A CN 1399542 A CN1399542 A CN 1399542A
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- mixture
- pharmaceutical composition
- polysorbate
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- 235000010290 biphenyl Nutrition 0.000 description 1
- 101150083127 brox gene Proteins 0.000 description 1
- 244000309464 bull Species 0.000 description 1
- 229960001948 caffeine Drugs 0.000 description 1
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 description 1
- 235000011089 carbon dioxide Nutrition 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- BHQCQFFYRZLCQQ-OELDTZBJSA-N cholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 BHQCQFFYRZLCQQ-OELDTZBJSA-N 0.000 description 1
- 235000019416 cholic acid Nutrition 0.000 description 1
- 229960002471 cholic acid Drugs 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 239000012050 conventional carrier Substances 0.000 description 1
- 150000003983 crown ethers Chemical class 0.000 description 1
- KXGVEGMKQFWNSR-UHFFFAOYSA-N deoxycholic acid Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 KXGVEGMKQFWNSR-UHFFFAOYSA-N 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 150000005690 diesters Chemical class 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 239000013583 drug formulation Substances 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- HQPMKSGTIOYHJT-UHFFFAOYSA-N ethane-1,2-diol;propane-1,2-diol Chemical compound OCCO.CC(O)CO HQPMKSGTIOYHJT-UHFFFAOYSA-N 0.000 description 1
- OAYLNYINCPYISS-UHFFFAOYSA-N ethyl acetate;hexane Chemical compound CCCCCC.CCOC(C)=O OAYLNYINCPYISS-UHFFFAOYSA-N 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 229960004222 factor ix Drugs 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 229940015043 glyoxal Drugs 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- FJQXCDYVZAHXNS-UHFFFAOYSA-N methadone hydrochloride Chemical compound Cl.C=1C=CC=CC=1C(CC(C)N(C)C)(C(=O)CC)C1=CC=CC=C1 FJQXCDYVZAHXNS-UHFFFAOYSA-N 0.000 description 1
- POULHZVOKOAJMA-UHFFFAOYSA-N methyl undecanoic acid Natural products CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 1
- 229940105132 myristate Drugs 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000003336 oxytocin antagonist Substances 0.000 description 1
- 229940121361 oxytocin antagonists Drugs 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000005453 pelletization Methods 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- WZHBNYSKBIVGKW-UHFFFAOYSA-N pyrido[2,3-i][1,2]benzothiazepine Chemical group S1N=CC=CC2=CC=C(N=CC=C3)C3=C12 WZHBNYSKBIVGKW-UHFFFAOYSA-N 0.000 description 1
- YUOCYTRGANSSRY-UHFFFAOYSA-N pyrrolo[2,3-i][1,2]benzodiazepine Chemical group C1=CN=NC2=C3C=CN=C3C=CC2=C1 YUOCYTRGANSSRY-UHFFFAOYSA-N 0.000 description 1
- 239000002464 receptor antagonist Substances 0.000 description 1
- 229940044551 receptor antagonist Drugs 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 239000012056 semi-solid material Substances 0.000 description 1
- 239000011257 shell material Substances 0.000 description 1
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical class O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
- 230000007928 solubilization Effects 0.000 description 1
- 238000005063 solubilization Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000003019 stabilising effect Effects 0.000 description 1
- 229940035023 sucrose monostearate Drugs 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- PVNIQBQSYATKKL-UHFFFAOYSA-N tripalmitin Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCC PVNIQBQSYATKKL-UHFFFAOYSA-N 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000007738 vacuum evaporation Methods 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 108010047303 von Willebrand Factor Proteins 0.000 description 1
- 102100036537 von Willebrand factor Human genes 0.000 description 1
- 229960001134 von willebrand factor Drugs 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40616499A | 1999-09-27 | 1999-09-27 | |
| US09/406,164 | 1999-09-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1399542A true CN1399542A (zh) | 2003-02-26 |
Family
ID=23606801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN00816307A Pending CN1399542A (zh) | 1999-09-27 | 2000-09-26 | 药用载体制剂 |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1216029A1 (es) |
| JP (1) | JP2003510267A (es) |
| KR (1) | KR20020064289A (es) |
| CN (1) | CN1399542A (es) |
| AR (1) | AR025867A1 (es) |
| AU (1) | AU7716100A (es) |
| BR (1) | BR0014308A (es) |
| CA (1) | CA2388471A1 (es) |
| CZ (1) | CZ20021082A3 (es) |
| EA (1) | EA200200415A1 (es) |
| HK (1) | HK1044485A1 (es) |
| HU (1) | HUP0202652A3 (es) |
| IL (1) | IL148543A0 (es) |
| MX (1) | MXPA02003190A (es) |
| NO (1) | NO20021476L (es) |
| PL (1) | PL354331A1 (es) |
| WO (1) | WO2001022942A1 (es) |
| ZA (1) | ZA200203311B (es) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100342856C (zh) * | 2003-04-10 | 2007-10-17 | 上海医药工业研究院 | 达那唑半固体骨架制剂的组合物 |
| CN101360485B (zh) * | 2005-10-26 | 2013-04-17 | 班纳制药公司 | 作为胶囊填充物的基于亲水性载体的双重控释基质系统 |
| CN111032004A (zh) * | 2017-12-20 | 2020-04-17 | 弗门尼舍有限公司 | 口腔护理组合物 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7138393B2 (en) | 1998-07-24 | 2006-11-21 | Wyeth | Biologically active vasopressin agonist metabolites |
| US20030105144A1 (en) * | 2001-04-17 | 2003-06-05 | Ping Gao | Stabilized oral pharmaceutical composition |
| WO2004073692A1 (ja) * | 2003-02-18 | 2004-09-02 | Yamashita, Shinji | 難水溶性薬物のハードカプセル剤 |
| JP5406529B2 (ja) | 2005-10-26 | 2014-02-05 | バナー ファーマキャプス， インコーポレイテッド | カプセル充墳物としての親油性ベヒクルに基づく二重制御された放出マトリクスシステム |
| EP2068829A2 (en) * | 2006-10-31 | 2009-06-17 | Wyeth | Semi-solid formulations of phospholipase enzyme inhibitors |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3636123A1 (de) * | 1986-10-23 | 1988-05-05 | Rentschler Arzneimittel | Arzneizubereitungen zur oralen verabreichung, die als einzeldosis 10 bis 240 mg dihydropyridin enthalten |
| WO1995022331A1 (en) * | 1994-02-18 | 1995-08-24 | Cephalon, Inc. | Aqueous indolocarbazole solutions |
| EP1049459B1 (en) * | 1998-01-20 | 2009-04-22 | Applied Analytical Industries, Inc. | Oral liquid compositions |
-
2000
- 2000-09-26 MX MXPA02003190A patent/MXPA02003190A/es unknown
- 2000-09-26 EP EP00966880A patent/EP1216029A1/en not_active Withdrawn
- 2000-09-26 BR BR0014308-1A patent/BR0014308A/pt not_active Application Discontinuation
- 2000-09-26 AR ARP000105037A patent/AR025867A1/es unknown
- 2000-09-26 KR KR1020027003934A patent/KR20020064289A/ko not_active Application Discontinuation
- 2000-09-26 WO PCT/US2000/026381 patent/WO2001022942A1/en not_active Application Discontinuation
- 2000-09-26 IL IL14854300A patent/IL148543A0/xx unknown
- 2000-09-26 EA EA200200415A patent/EA200200415A1/ru unknown
- 2000-09-26 PL PL00354331A patent/PL354331A1/xx not_active Application Discontinuation
- 2000-09-26 AU AU77161/00A patent/AU7716100A/en not_active Abandoned
- 2000-09-26 CZ CZ20021082A patent/CZ20021082A3/cs unknown
- 2000-09-26 HU HU0202652A patent/HUP0202652A3/hu unknown
- 2000-09-26 CN CN00816307A patent/CN1399542A/zh active Pending
- 2000-09-26 JP JP2001526154A patent/JP2003510267A/ja active Pending
- 2000-09-26 CA CA002388471A patent/CA2388471A1/en not_active Abandoned
-
2002
- 2002-03-25 NO NO20021476A patent/NO20021476L/no not_active Application Discontinuation
- 2002-04-25 ZA ZA200203311A patent/ZA200203311B/xx unknown
- 2002-08-23 HK HK02106196.7A patent/HK1044485A1/zh unknown
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100342856C (zh) * | 2003-04-10 | 2007-10-17 | 上海医药工业研究院 | 达那唑半固体骨架制剂的组合物 |
| CN101360485B (zh) * | 2005-10-26 | 2013-04-17 | 班纳制药公司 | 作为胶囊填充物的基于亲水性载体的双重控释基质系统 |
| CN111032004A (zh) * | 2017-12-20 | 2020-04-17 | 弗门尼舍有限公司 | 口腔护理组合物 |
| CN111032004B (zh) * | 2017-12-20 | 2023-10-20 | 弗门尼舍有限公司 | 口腔护理组合物 |
| US11938209B2 (en) | 2017-12-20 | 2024-03-26 | Firmenich Sa | Oral care compositions |
Also Published As
| Publication number | Publication date |
|---|---|
| AR025867A1 (es) | 2002-12-18 |
| ZA200203311B (en) | 2003-12-31 |
| IL148543A0 (en) | 2002-09-12 |
| BR0014308A (pt) | 2002-05-21 |
| HUP0202652A3 (en) | 2004-06-28 |
| HK1044485A1 (zh) | 2002-10-25 |
| MXPA02003190A (es) | 2002-09-30 |
| AU7716100A (en) | 2001-04-30 |
| JP2003510267A (ja) | 2003-03-18 |
| NO20021476D0 (no) | 2002-03-25 |
| HUP0202652A2 (hu) | 2004-05-28 |
| CZ20021082A3 (cs) | 2002-06-12 |
| CA2388471A1 (en) | 2001-04-05 |
| KR20020064289A (ko) | 2002-08-07 |
| EP1216029A1 (en) | 2002-06-26 |
| PL354331A1 (en) | 2004-01-12 |
| WO2001022942A1 (en) | 2001-04-05 |
| NO20021476L (no) | 2002-04-16 |
| EA200200415A1 (ru) | 2002-10-31 |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
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