CN1391483A - 作为佐剂的聚氧乙烯脱水山梨醇酯和辛苯昔醇组合及其在疫苗中的应用 - Google Patents
作为佐剂的聚氧乙烯脱水山梨醇酯和辛苯昔醇组合及其在疫苗中的应用 Download PDFInfo
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- CN1391483A CN1391483A CN00816014A CN00816014A CN1391483A CN 1391483 A CN1391483 A CN 1391483A CN 00816014 A CN00816014 A CN 00816014A CN 00816014 A CN00816014 A CN 00816014A CN 1391483 A CN1391483 A CN 1391483A
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Classifications
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Epidemiology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- AIDS & HIV (AREA)
- Otolaryngology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9922703.5A GB9922703D0 (en) | 1999-09-24 | 1999-09-24 | Vaccine |
| GB9922703.5 | 1999-09-24 | ||
| GB0016685A GB0016685D0 (en) | 2000-07-06 | 2000-07-06 | Novel compounds |
| GB0016685.0 | 2000-07-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1391483A true CN1391483A (zh) | 2003-01-15 |
Family
ID=26244613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN00816014A Pending CN1391483A (zh) | 1999-09-24 | 2000-09-22 | 作为佐剂的聚氧乙烯脱水山梨醇酯和辛苯昔醇组合及其在疫苗中的应用 |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1221971A2 (fr) |
| JP (1) | JP2003509473A (fr) |
| KR (1) | KR20020038770A (fr) |
| CN (1) | CN1391483A (fr) |
| AU (1) | AU765824B2 (fr) |
| BR (1) | BR0014282A (fr) |
| CA (1) | CA2383413A1 (fr) |
| CO (1) | CO5200837A1 (fr) |
| CZ (1) | CZ20021043A3 (fr) |
| HK (1) | HK1049106A1 (fr) |
| HU (1) | HUP0202885A3 (fr) |
| IL (1) | IL148672A0 (fr) |
| MX (1) | MXPA02003067A (fr) |
| NO (1) | NO20021433L (fr) |
| PL (1) | PL355163A1 (fr) |
| TR (1) | TR200200774T2 (fr) |
| WO (1) | WO2001021207A2 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI750929B (zh) * | 2020-12-02 | 2021-12-21 | 林建宏 | 氣霧免疫用之溫敏型佐劑及其製作方法 |
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| AU1463097A (en) | 1996-01-04 | 1997-08-01 | Rican Limited | Helicobacter pylori bacterioferritin |
| NZ560966A (en) | 2000-10-27 | 2010-06-25 | Novartis Vaccines & Diagnostic | Nucleic acids and proteins from streptococcus groups A & B |
| JP2004535765A (ja) | 2000-12-07 | 2004-12-02 | カイロン コーポレイション | 前立腺癌においてアップレギュレートされた内因性レトロウイルス |
| MY134424A (en) * | 2001-05-30 | 2007-12-31 | Saechsisches Serumwerk | Stable influenza virus preparations with low or no amount of thiomersal |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| US8481043B2 (en) | 2001-06-22 | 2013-07-09 | Cpex Pharmaceuticals, Inc. | Nasal immunization |
| GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| AR045702A1 (es) | 2001-10-03 | 2005-11-09 | Chiron Corp | Composiciones de adyuvantes. |
| EP2572707A3 (fr) | 2002-02-20 | 2013-11-06 | Novartis Vaccines and Diagnostics, Inc. | Microparticules avec des molécules contenant un polypeptide adsorbé |
| US8518694B2 (en) | 2002-06-13 | 2013-08-27 | Novartis Vaccines And Diagnostics, Inc. | Nucleic acid vector comprising a promoter and a sequence encoding a polypeptide from the endogenous retrovirus PCAV |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| SI1549338T1 (sl) | 2002-10-11 | 2011-04-29 | Novartis Vaccines & Diagnostic | Polipeptidna cepiva za ĺ iroko zaĺ äśito pred hipervirulentnimi miningokoknimi rodovi |
| DK2279746T3 (da) | 2002-11-15 | 2013-11-25 | Novartis Vaccines & Diagnostic | Overfladeproteiner i neisseria meningitidis |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| US8034378B2 (en) | 2002-12-27 | 2011-10-11 | Novartis Vaccines And Diagnostics, Inc | Immunogenic compositions containing phospholipid |
| ES2411080T3 (es) | 2003-01-30 | 2013-07-04 | Novartis Ag | Vacunas inyectables contra múltiples serogrupos de meningococos |
| GB0308198D0 (en) | 2003-04-09 | 2003-05-14 | Chiron Srl | ADP-ribosylating bacterial toxin |
| NZ543467A (en) | 2003-04-10 | 2008-07-31 | Novartis Vaccines & Diagnostic | The severe acute respiratory syndrome coronavirus |
| JP5557415B2 (ja) | 2003-06-02 | 2014-07-23 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | 吸着させたトキソイドおよび多糖類含有抗原を含む微粒子に基づく免疫原性組成物 |
| US20060035242A1 (en) | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
| GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| PL1961426T3 (pl) | 2003-10-02 | 2012-03-30 | Gsk Vaccines S R L | Skojarzone szczepionki przeciwko zapaleniu opon mózgowo-rdzeniowych |
| US20080254065A1 (en) | 2004-03-09 | 2008-10-16 | Chiron Corporation | Influenza Virus Vaccines |
| GB0409745D0 (en) | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
| SI1740217T1 (sl) | 2004-04-30 | 2011-10-28 | Novartis Ag | Konjugirano meningokokno cepljenje |
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| EP2848692B1 (fr) | 2004-05-21 | 2017-08-16 | Novartis Vaccines and Diagnostics, Inc. | Vecteurs d'alphavirus de vaccins contre le virus de la grippe |
| EP2277595A3 (fr) | 2004-06-24 | 2011-09-28 | Novartis Vaccines and Diagnostics, Inc. | Composés pour potentialiser l'immunité |
| US20060165716A1 (en) | 2004-07-29 | 2006-07-27 | Telford John L | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| NZ555937A (en) | 2005-01-27 | 2009-05-31 | Childrens Hosp & Res Ct Oak | GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis |
| GB0502095D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
| EP1858919B1 (fr) | 2005-02-18 | 2012-04-04 | Novartis Vaccines and Diagnostics, Inc. | Immunogenes d'escherichia coli uropathogene |
| LT2351772T (lt) | 2005-02-18 | 2016-10-10 | Glaxosmithkline Biologicals Sa | Baltymai ir nukleorūgštys iš su meningitu/sepsiu susijusių escherichia coli |
| US20090130127A1 (en) | 2005-08-01 | 2009-05-21 | Seiji Tokumoto | Adjuvant or Pharmaceutical Preparation for Transdermal or Transmucousal Administration |
| EP2357000A1 (fr) | 2005-10-18 | 2011-08-17 | Novartis Vaccines and Diagnostics, Inc. | Immunisations mucosiques et systémiques avec des particules de réplicon à alpha-virus |
| US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
| US20100158943A1 (en) * | 2005-11-04 | 2010-06-24 | Novartis Vaccines And Diagnostics Srl | Administration routes for priming/boosting with influenza vaccines |
| US10842867B2 (en) | 2005-11-04 | 2020-11-24 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
| ES2514316T3 (es) | 2005-11-22 | 2014-10-28 | Novartis Vaccines And Diagnostics, Inc. | Partículas similares a virus (VLPs) de Norovirus y Sapovirus |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
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| US8535683B2 (en) | 2006-03-22 | 2013-09-17 | Abbott Biologicals B.V. | Intranasal or inhalational administration of virosomes |
| ATE539079T1 (de) | 2006-03-23 | 2012-01-15 | Novartis Ag | Imidazochinoxalinverbindungen als immunmodulatoren |
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| WO2007126825A2 (fr) | 2006-03-31 | 2007-11-08 | Novartis Ag | Immunisation mucosale et parentérale combinée contre le vih |
| EP2035035A2 (fr) | 2006-06-09 | 2009-03-18 | Novartis AG | Compositions immunogenes pour streptococcus agalactiae |
| GB0614460D0 (en) | 2006-07-20 | 2006-08-30 | Novartis Ag | Vaccines |
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| CA3016948A1 (fr) | 2006-09-11 | 2008-03-20 | Seqirus UK Limited | Fabrication de vaccins contre le virus grippal sans utiliser d'oeufs |
| EA200900784A1 (ru) | 2006-12-06 | 2009-12-30 | Новартис Аг | Вакцины, включающие антиген из четырех штаммов вируса гриппа |
| GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
| EP2123296B1 (fr) * | 2007-01-31 | 2019-05-22 | Hisamitsu Pharmaceutical Co., Inc. | Adjuvant pour administration transdermique ou transmucosale et preparation pharmaceutique le contenant |
| EP2185191B1 (fr) | 2007-06-27 | 2012-09-12 | Novartis AG | Vaccins antigrippaux à faible teneur en additifs |
| GB0713880D0 (en) | 2007-07-17 | 2007-08-29 | Novartis Ag | Conjugate purification |
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| GB0818453D0 (en) | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
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| WO2009114485A2 (fr) | 2008-03-10 | 2009-09-17 | Children's Hospital & Research Center At Oakland | Protéines chimères de liaison du facteur h contenant un domaine b hétérologue, et procédés d’utilisation associés |
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| EP2659907A1 (fr) | 2012-05-01 | 2013-11-06 | Affiris AG | Compositions |
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| US4772466A (en) * | 1983-08-22 | 1988-09-20 | Syntex (U.S.A.) Inc. | Vaccines comprising polyoxypropylene-polyoxyethylene block polymer based adjuvants |
| NL8403195A (nl) * | 1984-10-19 | 1986-05-16 | Nederlanden Staat | Immunogene complexen en vaccins die deze bevatten. |
| CA1291036C (fr) * | 1986-04-23 | 1991-10-22 | Edwin I. Stoltz | Administration de medicaments par voie nasale |
| US5653987A (en) * | 1995-05-16 | 1997-08-05 | Modi; Pankaj | Liquid formulations for proteinic pharmaceuticals |
-
2000
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- 2000-09-22 IL IL14867200A patent/IL148672A0/xx unknown
- 2000-09-22 BR BR0014282-4A patent/BR0014282A/pt not_active Application Discontinuation
- 2000-09-22 MX MXPA02003067A patent/MXPA02003067A/es unknown
- 2000-09-22 CO CO00072096A patent/CO5200837A1/es not_active Application Discontinuation
- 2000-09-22 AU AU79070/00A patent/AU765824B2/en not_active Ceased
- 2000-09-22 EP EP00969296A patent/EP1221971A2/fr not_active Withdrawn
- 2000-09-22 TR TR2002/00774T patent/TR200200774T2/xx unknown
- 2000-09-22 CN CN00816014A patent/CN1391483A/zh active Pending
- 2000-09-22 KR KR1020027003832A patent/KR20020038770A/ko not_active Application Discontinuation
- 2000-09-22 JP JP2001524631A patent/JP2003509473A/ja active Pending
- 2000-09-22 HU HU0202885A patent/HUP0202885A3/hu unknown
- 2000-09-22 CZ CZ20021043A patent/CZ20021043A3/cs unknown
- 2000-09-22 WO PCT/EP2000/009366 patent/WO2001021207A2/fr not_active Application Discontinuation
- 2000-09-22 PL PL00355163A patent/PL355163A1/xx not_active Application Discontinuation
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2002
- 2002-03-21 NO NO20021433A patent/NO20021433L/no not_active Application Discontinuation
- 2002-12-19 HK HK02109233.6A patent/HK1049106A1/zh unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI750929B (zh) * | 2020-12-02 | 2021-12-21 | 林建宏 | 氣霧免疫用之溫敏型佐劑及其製作方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20020038770A (ko) | 2002-05-23 |
| IL148672A0 (en) | 2002-09-12 |
| WO2001021207A3 (fr) | 2001-09-27 |
| AU7907000A (en) | 2001-04-24 |
| BR0014282A (pt) | 2002-05-21 |
| WO2001021207A2 (fr) | 2001-03-29 |
| HUP0202885A3 (en) | 2004-07-28 |
| PL355163A1 (en) | 2004-04-05 |
| AU765824B2 (en) | 2003-10-02 |
| MXPA02003067A (es) | 2002-09-30 |
| HUP0202885A2 (hu) | 2002-12-28 |
| TR200200774T2 (tr) | 2002-08-21 |
| CZ20021043A3 (cs) | 2002-08-14 |
| NO20021433D0 (no) | 2002-03-21 |
| EP1221971A2 (fr) | 2002-07-17 |
| JP2003509473A (ja) | 2003-03-11 |
| HK1049106A1 (zh) | 2003-05-02 |
| NO20021433L (no) | 2002-05-21 |
| CA2383413A1 (fr) | 2001-03-29 |
| CO5200837A1 (es) | 2002-09-27 |
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