CN1330664A - 血小板衍生生长因子c、其编码dna及其应用 - Google Patents

血小板衍生生长因子c、其编码dna及其应用 Download PDF

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Publication number
CN1330664A
CN1330664A CN99811565A CN99811565A CN1330664A CN 1330664 A CN1330664 A CN 1330664A CN 99811565 A CN99811565 A CN 99811565A CN 99811565 A CN99811565 A CN 99811565A CN 1330664 A CN1330664 A CN 1330664A
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CN
China
Prior art keywords
pdgf
polypeptide
leu
ser
glu
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Pending
Application number
CN99811565A
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English (en)
Chinese (zh)
Inventor
乌尔夫·埃里克松
卡琳·奥瑟
李旭日
安尼卡·蓬滕
马尔科·于特拉
卡里·阿利塔洛
阿恩·厄斯特曼
卡尔－亨里克·黑尔丁
克里斯特·贝茨霍尔茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ludwig Institute for Cancer Research Ltd
Licentia Oy
Ludwig Institute for Cancer Research New York
Original Assignee
Ludwig Institute for Cancer Research Ltd
Licentia Oy
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Filing date
Publication date
Application filed by Ludwig Institute for Cancer Research Ltd, Licentia Oy filed Critical Ludwig Institute for Cancer Research Ltd
Publication of CN1330664A publication Critical patent/CN1330664A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN99811565A 1998-09-30 1999-09-30 血小板衍生生长因子c、其编码dna及其应用 Pending CN1330664A (zh)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US10246198P 1998-09-30 1998-09-30
US60/102,461 1998-09-30
US10810998P 1998-11-12 1998-11-12
US60/108,109 1998-11-12
US11074998P 1998-12-03 1998-12-03
US60/110,749 1998-12-03
US11300298P 1998-12-18 1998-12-18
US60/113,002 1998-12-18
US13542699P 1999-05-21 1999-05-21
US60/135,426 1999-05-21
US14402299P 1999-07-15 1999-07-15
US60/144,022 1999-07-15

Publications (1)

Publication Number Publication Date
CN1330664A true CN1330664A (zh) 2002-01-09

Family

ID=27557649

Family Applications (1)

Application Number Title Priority Date Filing Date
CN99811565A Pending CN1330664A (zh) 1998-09-30 1999-09-30 血小板衍生生长因子c、其编码dna及其应用

Country Status (5)

Country Link
EP (1) EP1123408A1 (fr)
JP (1) JP2002525086A (fr)
CN (1) CN1330664A (fr)
CA (1) CA2344561A1 (fr)
WO (1) WO2000018212A2 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104693285A (zh) * 2015-04-06 2015-06-10 苏州普罗达生物科技有限公司 血管内皮生长因子c拮抗多肽及其应用
CN104693286A (zh) * 2015-04-06 2015-06-10 苏州普罗达生物科技有限公司 关于血管内皮生长因子c拮抗多肽及其应用
CN104744565A (zh) * 2015-04-06 2015-07-01 苏州普罗达生物科技有限公司 一种血管内皮生长因子c拮抗多肽及其应用
CN105175546A (zh) * 2015-05-27 2015-12-23 连祺周 人血管内皮生长因子与表皮生长因子样结构域7的融合蛋白
CN109843918A (zh) * 2016-07-01 2019-06-04 旁分泌疗法公司 用于pdgf-cc抑制的方法和组合物

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1064382T3 (da) 1998-03-17 2008-12-08 Genentech Inc Homologe polypeptider til VEGF og BMP1
US6432673B1 (en) 1998-12-07 2002-08-13 Zymogenetics, Inc. Growth factor homolog ZVEGF3
ATE404668T1 (de) * 1998-12-07 2008-08-15 Zymogenetics Inc Wachstumsfaktor-homologe zvegf-3
WO2000059940A2 (fr) * 1999-04-06 2000-10-12 Eli Lilly And Company Gene et proteine lies au facteur de croissance d'origine plaquettaire
US6893637B1 (en) 1999-10-21 2005-05-17 Zymogenetics, Inc. Method of treating fibrosis
CA2426384A1 (fr) * 2000-10-19 2003-04-17 Kyowa Hakko Kogyo Co., Ltd. Anticorps inhibant l'activite vplf
KR20080083072A (ko) * 2001-03-09 2008-09-12 얀센 파마슈티카 엔.브이. Ｖｅｇｆ-ｘ 또는 그의 길항제에 의한 평활근 세포 증식의 조절
EP1678197A4 (fr) * 2003-10-24 2008-05-07 Ludwig Inst Cancer Res Methodes et compositions d'activation et d'inhibition de pdgf-c
US20060024302A1 (en) 2004-03-05 2006-02-02 Ludwig Institute For Cancer Research Chimeric anti-VEGF-D antibodies and humanized anti-VEGF-D antibodies and methods of using same
WO2005092921A2 (fr) * 2004-03-22 2005-10-06 Eli Lilly And Company Variants d'epissage du facteur de croissance placentaire, utilisations de ces derniers
WO2007022287A2 (fr) 2005-08-15 2007-02-22 Vegenics Limited Vegf-a modifié aux propriétés angiogéniques améliorées
ES2429225T3 (es) 2006-05-17 2013-11-13 The Ludwig Institute For Cancer Research Anticuerpos anti VEGF-B para tratamiento o profilaxis de diabetes de tipo II o síndrome metabólico
CN101392026B (zh) * 2008-10-09 2011-11-09 黄岚 用于预防和治疗纤维化类疾病以及肝癌的多肽
KR20150005631A (ko) 2012-04-24 2015-01-14 쓰롬보제닉스 엔.브이. 항-pdgf-c 항체

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104693285A (zh) * 2015-04-06 2015-06-10 苏州普罗达生物科技有限公司 血管内皮生长因子c拮抗多肽及其应用
CN104693286A (zh) * 2015-04-06 2015-06-10 苏州普罗达生物科技有限公司 关于血管内皮生长因子c拮抗多肽及其应用
CN104744565A (zh) * 2015-04-06 2015-07-01 苏州普罗达生物科技有限公司 一种血管内皮生长因子c拮抗多肽及其应用
CN105175546A (zh) * 2015-05-27 2015-12-23 连祺周 人血管内皮生长因子与表皮生长因子样结构域7的融合蛋白
CN109843918A (zh) * 2016-07-01 2019-06-04 旁分泌疗法公司 用于pdgf-cc抑制的方法和组合物
CN109843918B (zh) * 2016-07-01 2023-08-25 旁分泌疗法公司 用于pdgf-cc抑制的方法和组合物

Also Published As

Publication number Publication date
WO2000018212A9 (fr) 2000-09-08
EP1123408A1 (fr) 2001-08-16
CA2344561A1 (fr) 2000-04-06
WO2000018212A8 (fr) 2007-11-22
JP2002525086A (ja) 2002-08-13
WO2000018212A2 (fr) 2000-04-06

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