CA2344561A1 - Facteur de croissance c derive des plaquettes, adn le codant et ses utilisations - Google Patents

Facteur de croissance c derive des plaquettes, adn le codant et ses utilisations Download PDF

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Publication number
CA2344561A1
CA2344561A1 CA002344561A CA2344561A CA2344561A1 CA 2344561 A1 CA2344561 A1 CA 2344561A1 CA 002344561 A CA002344561 A CA 002344561A CA 2344561 A CA2344561 A CA 2344561A CA 2344561 A1 CA2344561 A1 CA 2344561A1
Authority
CA
Canada
Prior art keywords
pdgf
polypeptide
leu
glu
ser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002344561A
Other languages
English (en)
Inventor
Ulf Eriksson
Karin Aase
Xuri Li
Annica Ponten
Marko Uutela
Kari Alitalo
Arne Oestman
Carl-Henrik Heldin
Christer Betsholz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ludwig Institute for Cancer Research Ltd
Licentia Oy
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2344561A1 publication Critical patent/CA2344561A1/fr
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Publié sans précis
CA002344561A 1998-09-30 1999-09-30 Facteur de croissance c derive des plaquettes, adn le codant et ses utilisations Abandoned CA2344561A1 (fr)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US10246198P 1998-09-30 1998-09-30
US60/102,461 1998-09-30
US10810998P 1998-11-12 1998-11-12
US60/108,109 1998-11-12
US11074998P 1998-12-03 1998-12-03
US60/110,749 1998-12-03
US11300298P 1998-12-18 1998-12-18
US60/113,002 1998-12-18
US13542699P 1999-05-21 1999-05-21
US60/135,426 1999-05-21
US14402299P 1999-07-15 1999-07-15
US60/144,022 1999-07-15
PCT/US1999/022668 WO2000018212A2 (fr) 1998-09-30 1999-09-30 Facteur de croissance c derive des plaquettes, adn le codant et ses utilisations

Publications (1)

Publication Number Publication Date
CA2344561A1 true CA2344561A1 (fr) 2000-04-06

Family

ID=27557649

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002344561A Abandoned CA2344561A1 (fr) 1998-09-30 1999-09-30 Facteur de croissance c derive des plaquettes, adn le codant et ses utilisations

Country Status (5)

Country Link
EP (1) EP1123408A1 (fr)
JP (1) JP2002525086A (fr)
CN (1) CN1330664A (fr)
CA (1) CA2344561A1 (fr)
WO (1) WO2000018212A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4532733B2 (ja) 1998-03-17 2010-08-25 ジェネンテック， インコーポレイテッド Ｖｅｇｆおよびｂｍｐ１と相同なポリペプチド群
US6432673B1 (en) 1998-12-07 2002-08-13 Zymogenetics, Inc. Growth factor homolog ZVEGF3
EP1137773B1 (fr) * 1998-12-07 2008-08-13 ZymoGenetics, Inc. Zvegf3 homologue du facteur de croissance
AU4008500A (en) * 1999-04-06 2000-10-23 Eli Lilly And Company Platelet-derived growth factor related gene and protein
US6893637B1 (en) 1999-10-21 2005-05-17 Zymogenetics, Inc. Method of treating fibrosis
WO2002033094A1 (fr) * 2000-10-19 2002-04-25 Kyowa Hakko Kogyo Co., Ltd. Anticorps inhibant l'activite vplf
NZ527975A (en) 2001-03-09 2005-02-25 Janssen Pharmaceutica Nv Modulation of smooth muscle cell proliferation
EP1678197A4 (fr) * 2003-10-24 2008-05-07 Ludwig Inst Cancer Res Methodes et compositions d'activation et d'inhibition de pdgf-c
US20060024302A1 (en) 2004-03-05 2006-02-02 Ludwig Institute For Cancer Research Chimeric anti-VEGF-D antibodies and humanized anti-VEGF-D antibodies and methods of using same
WO2005092921A2 (fr) * 2004-03-22 2005-10-06 Eli Lilly And Company Variants d'epissage du facteur de croissance placentaire, utilisations de ces derniers
WO2007022287A2 (fr) 2005-08-15 2007-02-22 Vegenics Limited Vegf-a modifié aux propriétés angiogéniques améliorées
WO2007136679A2 (fr) 2006-05-17 2007-11-29 Ludwig Institute For Cancer Research Cibler la régulation du vegf-b des transporteurs d'acides gras afin de moduler les maladies humaines
CN101392026B (zh) * 2008-10-09 2011-11-09 黄岚 用于预防和治疗纤维化类疾病以及肝癌的多肽
NZ700274A (en) 2012-04-24 2016-10-28 Thrombogenics Nv Anti-pdgf-c antibodies
CN104693286A (zh) * 2015-04-06 2015-06-10 苏州普罗达生物科技有限公司 关于血管内皮生长因子c拮抗多肽及其应用
CN104744565A (zh) * 2015-04-06 2015-07-01 苏州普罗达生物科技有限公司 一种血管内皮生长因子c拮抗多肽及其应用
CN104693285A (zh) * 2015-04-06 2015-06-10 苏州普罗达生物科技有限公司 血管内皮生长因子c拮抗多肽及其应用
CN105175546A (zh) * 2015-05-27 2015-12-23 连祺周 人血管内皮生长因子与表皮生长因子样结构域7的融合蛋白
EP3478718A4 (fr) * 2016-07-01 2020-07-29 Paracrine Therapeutics AB Procédés et compositions pour l'inhibition du pdgf-cc

Also Published As

Publication number Publication date
WO2000018212A9 (fr) 2000-09-08
JP2002525086A (ja) 2002-08-13
EP1123408A1 (fr) 2001-08-16
WO2000018212A2 (fr) 2000-04-06
WO2000018212A8 (fr) 2007-11-22
CN1330664A (zh) 2002-01-09

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Legal Events

Date Code Title Description
FZDE Discontinued