CN1308450C - 诊断和治疗肿瘤的方法及组合物 - Google Patents

诊断和治疗肿瘤的方法及组合物 Download PDF

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Publication number
CN1308450C
CN1308450C CNB961995858A CN96199585A CN1308450C CN 1308450 C CN1308450 C CN 1308450C CN B961995858 A CNB961995858 A CN B961995858A CN 96199585 A CN96199585 A CN 96199585A CN 1308450 C CN1308450 C CN 1308450C
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cell
tumor
gene
adenovirus
expression vector
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CN1207771A (zh
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G·L·克雷曼
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University of Texas at Austin
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University of Texas System
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CNB961995858A 1995-11-30 1996-11-27 诊断和治疗肿瘤的方法及组合物 Expired - Lifetime CN1308450C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US781095P 1995-11-30 1995-11-30
US60/007,810 1995-11-30
US007810 1995-11-30

Related Child Applications (1)

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CNA2007100051249A Division CN101028523A (zh) 1995-11-30 1996-11-27 诊断和治疗肿瘤的方法及组合物

Publications (2)

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CN1207771A CN1207771A (zh) 1999-02-10
CN1308450C true CN1308450C (zh) 2007-04-04

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CNB961995858A Expired - Lifetime CN1308450C (zh) 1995-11-30 1996-11-27 诊断和治疗肿瘤的方法及组合物
CNA2007100051249A Pending CN101028523A (zh) 1995-11-30 1996-11-27 诊断和治疗肿瘤的方法及组合物

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EP (1) EP0863984B1 (enExample)
JP (1) JP2000501394A (enExample)
KR (1) KR19990071795A (enExample)
CN (2) CN1308450C (enExample)
AT (1) ATE325872T1 (enExample)
AU (1) AU722042B2 (enExample)
CA (1) CA2238829A1 (enExample)
CZ (1) CZ296810B6 (enExample)
DE (1) DE69636120T2 (enExample)
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HU (1) HUP9902068A3 (enExample)
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NZ (1) NZ324168A (enExample)
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RU (1) RU2174409C2 (enExample)
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Publication number Publication date
DE69636120T2 (de) 2006-11-30
EP0863984B1 (en) 2006-05-10
PL186018B1 (pl) 2003-09-30
CN101028523A (zh) 2007-09-05
HUP9902068A3 (en) 2001-02-28
US20060035857A1 (en) 2006-02-16
EP0863984A1 (en) 1998-09-16
ATE325872T1 (de) 2006-06-15
KR19990071795A (ko) 1999-09-27
US20020077313A1 (en) 2002-06-20
RU2174409C2 (ru) 2001-10-10
US20030166603A1 (en) 2003-09-04
NO982481L (no) 1998-07-29
JP2000501394A (ja) 2000-02-08
AU1126397A (en) 1997-06-19
NO982481D0 (no) 1998-05-29
HUP9902068A2 (hu) 1999-10-28
CA2238829A1 (en) 1997-06-05
PL327009A1 (en) 1998-11-09
NZ324168A (en) 2004-11-26
CZ165798A3 (cs) 1998-12-16
ES2264145T3 (es) 2006-12-16
CZ296810B6 (cs) 2006-06-14
SK70598A3 (en) 1999-04-13
CN1207771A (zh) 1999-02-10
WO1997020047A1 (en) 1997-06-05
DE69636120D1 (de) 2006-06-14
DK0863984T3 (da) 2006-08-28
AU722042B2 (en) 2000-07-20

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