CN1290829C - 制备环状硫代酰胺化合物的方法 - Google Patents

制备环状硫代酰胺化合物的方法 Download PDF

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Publication number
CN1290829C
CN1290829C CNB2004100014528A CN200410001452A CN1290829C CN 1290829 C CN1290829 C CN 1290829C CN B2004100014528 A CNB2004100014528 A CN B2004100014528A CN 200410001452 A CN200410001452 A CN 200410001452A CN 1290829 C CN1290829 C CN 1290829C
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CN
China
Prior art keywords
compound
formula
administration
reaction
preparation
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Expired - Fee Related
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CNB2004100014528A
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English (en)
Chinese (zh)
Other versions
CN1519230A (zh
Inventor
G·J·卡林科
J·W·拉格根
P·D·希尔
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Pfizer Products Inc
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Pfizer Products Inc
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Publication of CN1519230A publication Critical patent/CN1519230A/zh
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Publication of CN1290829C publication Critical patent/CN1290829C/zh
Anticipated expiration legal-status Critical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
CNB2004100014528A 1999-03-30 2000-03-30 制备环状硫代酰胺化合物的方法 Expired - Fee Related CN1290829C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12683199P 1999-03-30 1999-03-30
US60/126,831 1999-03-30

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB001048325A Division CN1163490C (zh) 1999-03-30 2000-03-30 制备环状硫代酰胺化合物的方法

Publications (2)

Publication Number Publication Date
CN1519230A CN1519230A (zh) 2004-08-11
CN1290829C true CN1290829C (zh) 2006-12-20

Family

ID=22426907

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB2004100014528A Expired - Fee Related CN1290829C (zh) 1999-03-30 2000-03-30 制备环状硫代酰胺化合物的方法
CNB001048325A Expired - Fee Related CN1163490C (zh) 1999-03-30 2000-03-30 制备环状硫代酰胺化合物的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNB001048325A Expired - Fee Related CN1163490C (zh) 1999-03-30 2000-03-30 制备环状硫代酰胺化合物的方法

Country Status (25)

Country Link
US (1) US6388127B1 (enExample)
EP (1) EP1041070B1 (enExample)
JP (1) JP3566175B2 (enExample)
KR (1) KR100386524B1 (enExample)
CN (2) CN1290829C (enExample)
AR (1) AR029744A1 (enExample)
AT (1) ATE277025T1 (enExample)
AU (1) AU777097B2 (enExample)
BR (1) BR0001492A (enExample)
CA (1) CA2302727C (enExample)
CZ (1) CZ298140B6 (enExample)
DE (1) DE60013942T2 (enExample)
DK (1) DK1041070T3 (enExample)
ES (1) ES2226715T3 (enExample)
HU (1) HUP0001327A3 (enExample)
ID (1) ID25428A (enExample)
IL (1) IL135243A (enExample)
IN (1) IN188844B (enExample)
PL (1) PL196446B1 (enExample)
PT (1) PT1041070E (enExample)
RU (1) RU2219173C2 (enExample)
TR (1) TR200000834A2 (enExample)
TW (1) TW460472B (enExample)
YU (1) YU15500A (enExample)
ZA (1) ZA200001536B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1041070T3 (da) * 1999-03-30 2005-01-24 Pfizer Prod Inc Fremgangsmåde til fremstilling af cykliske thioamider
WO2014039715A1 (en) 2012-09-07 2014-03-13 University Of Rochester Methods and compositions for site-specific labeling of peptides and proteins
US9999921B2 (en) 2015-06-15 2018-06-19 Gm Global Technology Operatioins Llc Method of making aluminum or magnesium based composite engine blocks or other parts with in-situ formed reinforced phases through squeeze casting or semi-solid metal forming and post heat treatment

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2755278A (en) * 1956-07-17 Thiamori
GB8412862D0 (en) * 1984-05-19 1984-06-27 Beecham Group Plc Compounds
EP0233287B1 (en) * 1984-10-04 1991-01-30 Zenyaku Kogyo Kabushikikaisha 1,4-thiazine derivatives, process for their preparation, and cardiotonics containing the same
CA2099233A1 (en) * 1992-06-29 1993-12-30 Conrad P. Dorn Morpholine and thiomorpholine tachykinin receptor antagonists
WO1994003652A1 (fr) 1992-07-31 1994-02-17 Yokota Corporation Co., Ltd. Procede permettant de fabriquer des metaux de haute purete a partir de ferrailles de metaux usines
GB9225377D0 (en) * 1992-12-04 1993-01-27 Ici Plc Herbicides
TW280812B (enExample) * 1993-07-02 1996-07-11 Bayer Ag
FR2715933B1 (fr) * 1994-02-07 1996-04-12 Oreal Nouveaux N-(hydroxyalkyl) carbamates d'alkyle et leurs applications en cosmétique, plus particulièrement dans des compositions capillaires.
US5663409A (en) * 1995-06-07 1997-09-02 Novus International, Inc. Process for the preparation of 3-(methylthio) propanal and 2-hydroxy-4-(methylthio) butanenitrile
UA56185C2 (uk) * 1996-09-30 2003-05-15 Пфайзер Інк. Аралкіл- та аралкіліденгетероциклічні лактами та іміди, фармацевтична композиція та спосіб лікування
DK1041070T3 (da) * 1999-03-30 2005-01-24 Pfizer Prod Inc Fremgangsmåde til fremstilling af cykliske thioamider

Also Published As

Publication number Publication date
TW460472B (en) 2001-10-21
HUP0001327A2 (hu) 2001-04-28
YU15500A (sh) 2002-03-18
PL196446B1 (pl) 2008-01-31
HU0001327D0 (en) 2000-06-28
IL135243A0 (en) 2001-05-20
EP1041070B1 (en) 2004-09-22
AU2263500A (en) 2000-10-05
DE60013942T2 (de) 2006-02-23
ES2226715T3 (es) 2005-04-01
DK1041070T3 (da) 2005-01-24
HUP0001327A3 (en) 2003-06-30
CZ20001142A3 (cs) 2000-12-13
AR029744A1 (es) 2003-07-16
CN1519230A (zh) 2004-08-11
ATE277025T1 (de) 2004-10-15
ID25428A (id) 2000-10-05
KR20010014647A (ko) 2001-02-26
CA2302727A1 (en) 2000-09-30
ZA200001536B (en) 2001-09-27
TR200000834A2 (tr) 2000-11-21
PL339287A1 (en) 2000-10-09
HK1064364A1 (en) 2005-01-28
EP1041070A1 (en) 2000-10-04
BR0001492A (pt) 2000-10-17
AU777097B2 (en) 2004-09-30
CZ298140B6 (cs) 2007-07-04
CN1273244A (zh) 2000-11-15
HK1032053A1 (en) 2001-07-06
DE60013942D1 (de) 2004-10-28
RU2219173C2 (ru) 2003-12-20
JP2000309581A (ja) 2000-11-07
KR100386524B1 (ko) 2003-06-02
CA2302727C (en) 2004-02-24
CN1163490C (zh) 2004-08-25
IN188844B (enExample) 2002-11-09
IL135243A (en) 2005-09-25
US6388127B1 (en) 2002-05-14
PT1041070E (pt) 2004-12-31
JP3566175B2 (ja) 2004-09-15

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