HUP0001327A2 - Eljárás ciklikus amidok előállítására és intermedierjeik - Google Patents

Eljárás ciklikus amidok előállítására és intermedierjeik

Info

Publication number
HUP0001327A2
HUP0001327A2 HU0001327A HUP0001327A HUP0001327A2 HU P0001327 A2 HUP0001327 A2 HU P0001327A2 HU 0001327 A HU0001327 A HU 0001327A HU P0001327 A HUP0001327 A HU P0001327A HU P0001327 A2 HUP0001327 A2 HU P0001327A2
Authority
HU
Hungary
Prior art keywords
intermediates
preparing
cyclic amides
compounds
imides
Prior art date
Application number
HU0001327A
Other languages
English (en)
Inventor
Paul David Hill
George Joseph Quallich
Jeffrey William Raggon
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of HU0001327D0 publication Critical patent/HU0001327D0/hu
Publication of HUP0001327A2 publication Critical patent/HUP0001327A2/hu
Publication of HUP0001327A3 publication Critical patent/HUP0001327A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

A találmány tárgya eljárás (I) általános képletű vegyületek -, ahol b értéke 0, 1, 2 vagy 3; Y jelentése oxigén-, kénatom, NH vagy N-acetil-csoport; és minden R3egymástól függetlenül halogénatom, ciano-, 1-6 szénatomos alkil- vagyalkoxicsoport, trifluor-metil-csoport - előállítására, amelyvegyületekből új aralkil és aralkilidén heterociklusos laktámok ésimidek állíthatók elő, mely utóbbiak szelektív szerotonin 1 (5-HT,)receptorok agonistái és antagonistái. A találmány kiterjed azeljárásban alkalmazott nyílt láncú intermedierekre is. Ó
HU0001327A 1999-03-30 2000-03-29 Process for preparing of cyclic amides and their intermediates HUP0001327A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12683199P 1999-03-30 1999-03-30

Publications (3)

Publication Number Publication Date
HU0001327D0 HU0001327D0 (en) 2000-06-28
HUP0001327A2 true HUP0001327A2 (hu) 2001-04-28
HUP0001327A3 HUP0001327A3 (en) 2003-06-30

Family

ID=22426907

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0001327A HUP0001327A3 (en) 1999-03-30 2000-03-29 Process for preparing of cyclic amides and their intermediates

Country Status (26)

Country Link
US (1) US6388127B1 (hu)
EP (1) EP1041070B1 (hu)
JP (1) JP3566175B2 (hu)
KR (1) KR100386524B1 (hu)
CN (2) CN1163490C (hu)
AR (1) AR029744A1 (hu)
AT (1) ATE277025T1 (hu)
AU (1) AU777097B2 (hu)
BR (1) BR0001492A (hu)
CA (1) CA2302727C (hu)
CZ (1) CZ298140B6 (hu)
DE (1) DE60013942T2 (hu)
DK (1) DK1041070T3 (hu)
ES (1) ES2226715T3 (hu)
HK (2) HK1032053A1 (hu)
HU (1) HUP0001327A3 (hu)
ID (1) ID25428A (hu)
IL (1) IL135243A (hu)
IN (1) IN188844B (hu)
PL (1) PL196446B1 (hu)
PT (1) PT1041070E (hu)
RU (1) RU2219173C2 (hu)
TR (1) TR200000834A2 (hu)
TW (1) TW460472B (hu)
YU (1) YU15500A (hu)
ZA (1) ZA200001536B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU15500A (sh) * 1999-03-30 2002-03-18 Pfizer Products Inc. Postupak za dobijanje cikličnih tioamida
WO2014039715A1 (en) 2012-09-07 2014-03-13 University Of Rochester Methods and compositions for site-specific labeling of peptides and proteins
US9999921B2 (en) 2015-06-15 2018-06-19 Gm Global Technology Operatioins Llc Method of making aluminum or magnesium based composite engine blocks or other parts with in-situ formed reinforced phases through squeeze casting or semi-solid metal forming and post heat treatment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2755278A (en) * 1956-07-17 Thiamori
WO1994003652A1 (en) 1992-07-31 1994-02-17 Yokota Corporation Co., Ltd. Method of making metal of high purity from scrap of worked metal
GB9225377D0 (en) * 1992-12-04 1993-01-27 Ici Plc Herbicides
UA56185C2 (uk) * 1996-09-30 2003-05-15 Пфайзер Інк. Аралкіл- та аралкіліденгетероциклічні лактами та іміди, фармацевтична композиція та спосіб лікування
YU15500A (sh) * 1999-03-30 2002-03-18 Pfizer Products Inc. Postupak za dobijanje cikličnih tioamida

Also Published As

Publication number Publication date
HUP0001327A3 (en) 2003-06-30
BR0001492A (pt) 2000-10-17
KR20010014647A (ko) 2001-02-26
AU2263500A (en) 2000-10-05
YU15500A (sh) 2002-03-18
CZ20001142A3 (cs) 2000-12-13
HU0001327D0 (en) 2000-06-28
CN1519230A (zh) 2004-08-11
CA2302727C (en) 2004-02-24
CN1290829C (zh) 2006-12-20
TW460472B (en) 2001-10-21
ID25428A (id) 2000-10-05
DK1041070T3 (da) 2005-01-24
CN1163490C (zh) 2004-08-25
HK1064364A1 (en) 2005-01-28
ES2226715T3 (es) 2005-04-01
EP1041070A1 (en) 2000-10-04
IL135243A0 (en) 2001-05-20
CN1273244A (zh) 2000-11-15
PT1041070E (pt) 2004-12-31
JP2000309581A (ja) 2000-11-07
US6388127B1 (en) 2002-05-14
DE60013942T2 (de) 2006-02-23
CZ298140B6 (cs) 2007-07-04
EP1041070B1 (en) 2004-09-22
KR100386524B1 (ko) 2003-06-02
CA2302727A1 (en) 2000-09-30
AR029744A1 (es) 2003-07-16
TR200000834A2 (tr) 2000-11-21
IL135243A (en) 2005-09-25
PL196446B1 (pl) 2008-01-31
DE60013942D1 (de) 2004-10-28
RU2219173C2 (ru) 2003-12-20
ZA200001536B (en) 2001-09-27
IN188844B (hu) 2002-11-09
HK1032053A1 (en) 2001-07-06
AU777097B2 (en) 2004-09-30
ATE277025T1 (de) 2004-10-15
JP3566175B2 (ja) 2004-09-15
PL339287A1 (en) 2000-10-09

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