CN1264425A - 用于诊断和治疗的呼吸道合胞病毒表位和含有它们的抗体 - Google Patents

用于诊断和治疗的呼吸道合胞病毒表位和含有它们的抗体 Download PDF

Info

Publication number
CN1264425A
CN1264425A CN98807304A CN98807304A CN1264425A CN 1264425 A CN1264425 A CN 1264425A CN 98807304 A CN98807304 A CN 98807304A CN 98807304 A CN98807304 A CN 98807304A CN 1264425 A CN1264425 A CN 1264425A
Authority
CN
China
Prior art keywords
seq
peptide
antibody
rsv
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN98807304A
Other languages
English (en)
Chinese (zh)
Inventor
T·N·恩谷元
U·泊尔
L·格斯特克
A·贝克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of CN1264425A publication Critical patent/CN1264425A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027Paramyxoviridae, e.g. respiratory syncytial virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN98807304A 1997-07-17 1998-07-17 用于诊断和治疗的呼吸道合胞病毒表位和含有它们的抗体 Pending CN1264425A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR97/09079 1997-07-17
FR9709079A FR2766192B1 (fr) 1997-07-17 1997-07-17 Epitopes du vrs et anticorps les comportant, utiles dans le diagnostic et la therapie

Publications (1)

Publication Number Publication Date
CN1264425A true CN1264425A (zh) 2000-08-23

Family

ID=9509314

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98807304A Pending CN1264425A (zh) 1997-07-17 1998-07-17 用于诊断和治疗的呼吸道合胞病毒表位和含有它们的抗体

Country Status (8)

Country Link
EP (1) EP1003851A2 (ja)
JP (1) JP2001510039A (ja)
CN (1) CN1264425A (ja)
AU (1) AU756110B2 (ja)
BR (1) BR9810907A (ja)
CA (1) CA2296736A1 (ja)
FR (1) FR2766192B1 (ja)
WO (1) WO1999003987A2 (ja)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100528896C (zh) * 2004-02-03 2009-08-19 中国人民解放军军事医学科学院毒物药物研究所 用于预防、诊断和治疗呼吸道合胞病毒感染的嵌合抗原及其抗体
CN101130765B (zh) * 2006-08-21 2011-04-06 北京阿斯可来生物工程有限公司 呼吸道合胞病毒检测试剂盒
CN102711818A (zh) * 2009-08-04 2012-10-03 美利坚合众国政府疾病控制和预防中心 抗rsv免疫原和免疫方法
CN103163302A (zh) * 2011-12-10 2013-06-19 石家庄恩泽药品技术开发有限公司 一种采用定向交叉偶联技术制备的短肽抗体试剂盒
CN101808663B (zh) * 2007-10-25 2015-09-30 特雷利斯生物科学股份有限公司 抗rsv g蛋白抗体
CN106397547A (zh) * 2016-11-28 2017-02-15 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432435A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432436A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432437A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432438A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432439A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106518988A (zh) * 2016-11-28 2017-03-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106749555A (zh) * 2016-11-28 2017-05-31 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106749556A (zh) * 2016-11-28 2017-05-31 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN112409481A (zh) * 2020-12-01 2021-02-26 福州捷赫生物科技有限公司 抗p40蛋白单克隆抗体、细胞系及其制备方法和应用

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790959B1 (fr) * 1999-03-15 2003-06-27 Pf Medicament Utilisation de fractions membranaires bacteriennes a effet adjuvant, leurs procedes de preparation et composition pharmaceutique les contenant
GB9920000D0 (en) * 1999-08-25 1999-10-27 Imp Cancer Res Tech Polypeptides
FR2798857B1 (fr) * 1999-09-23 2003-06-06 Pf Medicament Utilisation d'une proteine de membrane ompa d'enterobacterie associee a un peptide immunogene du vrs pour la preparation de vaccins administrables par voie nasale
FR2805163A1 (fr) * 2000-02-21 2001-08-24 Pf Medicament Utilisation d'un detergent de type zwittergent pour la preparation d'une composition pharmaceutique destinee a etre administree par voie nasale
EP1174506A1 (en) * 2000-06-28 2002-01-23 Stichting Dienst Landbouwkundig Onderzoek C-terminal Erns peptide and analogues thereof
FR2819810B1 (fr) * 2001-01-23 2004-05-28 Pf Medicament Peptides non glycosyles derives de la proteine g du vrs et leur utilisation dans un vaccin
FR2827605B1 (fr) 2001-07-20 2004-07-16 Pf Medicament Nouveaux peptides derives de la proteine g du vrs et leur utilisation dans un vaccin
SI1472286T1 (sl) * 2002-02-05 2007-08-31 Geymonat Spa Postopek proizvodnje rekombinantnega placentnega rastnega faktorja
EP1768993A4 (en) * 2004-06-16 2008-07-23 Univ Johns Hopkins CYSTEINE-RICH REGION OF SYNCYTIAL RESPIRATORY VIRUS AND METHODS OF USE THEREOF

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223254A (en) * 1987-09-29 1993-06-29 Praxis Biologics, Inc. Respiratory syncytial virus: vaccines
SE9101433D0 (sv) * 1991-05-13 1991-05-13 Marianne Hansson Recombinant dna sequence and its use
FR2718452B1 (fr) * 1994-04-06 1996-06-28 Pf Medicament Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation.
AU710713B2 (en) * 1994-08-25 1999-09-30 Stichting Instituut Voor Dierhouderij En Diergezondheid Antigenic peptides derived from the G protein of RSV for type- and subtype-specific diagnosis of respiratory syncytial virus (RSV) infection
FR2726471B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Procede pour ameliorer l'immunogenicite d'un compose immunogene ou d'un haptene et application a la preparation de vaccins
FR2726576B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Production de peptides analogues de peptides hydrophobes, peptide recombinant, sequence d'adn correspondante
FR2726472B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin
FR2726577B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Procede d'obtention d'un peptide derive du virus respiratoire syncitial, polypeptide et bacterie l'exprimant, et leurs applications a titre de medicament
AUPO026596A0 (en) * 1996-06-05 1996-06-27 Biomolecular Research Institute Limited Viral peptide

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100528896C (zh) * 2004-02-03 2009-08-19 中国人民解放军军事医学科学院毒物药物研究所 用于预防、诊断和治疗呼吸道合胞病毒感染的嵌合抗原及其抗体
CN101130765B (zh) * 2006-08-21 2011-04-06 北京阿斯可来生物工程有限公司 呼吸道合胞病毒检测试剂盒
CN101808663B (zh) * 2007-10-25 2015-09-30 特雷利斯生物科学股份有限公司 抗rsv g蛋白抗体
CN102711818A (zh) * 2009-08-04 2012-10-03 美利坚合众国政府疾病控制和预防中心 抗rsv免疫原和免疫方法
CN102711818B (zh) * 2009-08-04 2014-09-24 美利坚合众国政府疾病控制和预防中心,健康和公共事业部 抗rsv免疫原和免疫方法
CN103163302A (zh) * 2011-12-10 2013-06-19 石家庄恩泽药品技术开发有限公司 一种采用定向交叉偶联技术制备的短肽抗体试剂盒
CN103163302B (zh) * 2011-12-10 2015-06-03 河北菲尼斯生物技术有限公司 一种采用定向交叉偶联技术制备的短肽抗体试剂盒
CN106432435A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106397547A (zh) * 2016-11-28 2017-02-15 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432436A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432437A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432438A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432439A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106518988A (zh) * 2016-11-28 2017-03-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106749555A (zh) * 2016-11-28 2017-05-31 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106749556A (zh) * 2016-11-28 2017-05-31 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN112409481A (zh) * 2020-12-01 2021-02-26 福州捷赫生物科技有限公司 抗p40蛋白单克隆抗体、细胞系及其制备方法和应用
CN112409481B (zh) * 2020-12-01 2024-03-26 福州捷赫生物科技有限公司 抗p40蛋白单克隆抗体、细胞系及其制备方法和应用

Also Published As

Publication number Publication date
WO1999003987A3 (fr) 1999-04-08
JP2001510039A (ja) 2001-07-31
WO1999003987A2 (fr) 1999-01-28
CA2296736A1 (fr) 1999-01-28
AU8812398A (en) 1999-02-10
AU756110B2 (en) 2003-01-02
EP1003851A2 (fr) 2000-05-31
FR2766192B1 (fr) 2001-07-13
FR2766192A1 (fr) 1999-01-22
BR9810907A (pt) 2000-08-01

Similar Documents

Publication Publication Date Title
CN1264425A (zh) 用于诊断和治疗的呼吸道合胞病毒表位和含有它们的抗体
CN1111540C (zh) 串联的合成hiv-1肽类
KR20170102905A (ko) 신규 다가 나노입자 기반 백신
CN1091138A (zh) 疫苗
CN1688606A (zh) 含有辅助t细胞和b细胞表位的新的免疫原性脂肽
JP2003529319A (ja) HIV−1gp41を標的化する広範に中和する抗体を誘発する方法
LU87861A1 (fr) Agent viral
CN1094640A (zh) 以脲酶为基础的抗螺杆菌感染的疫苗
CN1073878A (zh) 用病毒抗原表达特异性免疫原
CN1062605C (zh) 大肠杆菌疫苗的制备方法
CN1020857C (zh) 相应于轮状病毒的主要中和蛋白质的抗原和免疫决定子的肽
JPH09510458A (ja) ペプチドワクチン及びそれに関係する方法
IE60671B1 (en) Monoclonal antiobodies to HIV and related peptides
US5736378A (en) Molecular cloning and characterization of the feline immunodeficiency virus isolate PPR
JP2009022186A (ja) 抗原ペプチドおよびその利用
CA2132742C (en) Synthetic peptides and vaccines against parvovirus
US4810491A (en) Polypeptides useful in vaccination against enteroviruses
CN111978411A (zh) 一种猪蓝耳病亚单位疫苗及其制备方法与应用
CN1194001A (zh) 鸡贫血症病毒的中和构象表位
CN1082053A (zh) 合成多肽
EP4190799A1 (en) Amino acid sequence derived from sars-cov-2 and use thereof
CN1130911A (zh) 用于对抗hiv的多分支型肽构建物
EP0670901A1 (en) Polypeptide fragment capable of inducing neutralising antibodies against feline immuno-deficiency virus
CN1053642A (zh) 传染性支气管炎病毒疫苗
CN1280310C (zh) 具有防治流感作用的融合蛋白及其编码基因与应用

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication