CN1262667C - 利用颗粒标记物检测分析物 - Google Patents

利用颗粒标记物检测分析物 Download PDF

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Publication number
CN1262667C
CN1262667C CNB971958688A CN97195868A CN1262667C CN 1262667 C CN1262667 C CN 1262667C CN B971958688 A CNB971958688 A CN B971958688A CN 97195868 A CN97195868 A CN 97195868A CN 1262667 C CN1262667 C CN 1262667C
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China
Prior art keywords
particles
light
particle
scattering
analytes
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Expired - Fee Related
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CNB971958688A
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English (en)
Chinese (zh)
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CN1223692A (zh
Inventor
J·伊格拉比德
E·E·伊格拉比德
D·E·克纳
J·T·杰克森
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GENECOM Inc
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GENECOM Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0038—Investigating nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493—Particle size

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNB971958688A 1996-04-25 1997-04-17 利用颗粒标记物检测分析物 Expired - Fee Related CN1262667C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1638396P 1996-04-25 1996-04-25
US60/016,383 1996-04-25

Publications (2)

Publication Number Publication Date
CN1223692A CN1223692A (zh) 1999-07-21
CN1262667C true CN1262667C (zh) 2006-07-05

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CNB971958688A Expired - Fee Related CN1262667C (zh) 1996-04-25 1997-04-17 利用颗粒标记物检测分析物

Country Status (12)

Country Link
US (1) US6214560B1 (enExample)
EP (1) EP1021554B1 (enExample)
JP (3) JP2000510582A (enExample)
CN (1) CN1262667C (enExample)
AT (1) ATE357663T1 (enExample)
AU (1) AU736340B2 (enExample)
BR (1) BR9710836A (enExample)
CA (1) CA2253710A1 (enExample)
DE (1) DE69737513T2 (enExample)
IL (1) IL126544A (enExample)
RU (1) RU2251572C2 (enExample)
WO (1) WO1997040181A1 (enExample)

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AU736340B2 (en) 2001-07-26
DE69737513T2 (de) 2007-12-13
US6214560B1 (en) 2001-04-10
ATE357663T1 (de) 2007-04-15
RU2251572C2 (ru) 2005-05-10
EP1021554A4 (en) 2004-06-30
JP2000510582A (ja) 2000-08-15
WO1997040181A1 (en) 1997-10-30
IL126544A (en) 2004-08-31
JP2007263974A (ja) 2007-10-11
IL126544A0 (en) 1999-08-17
CN1223692A (zh) 1999-07-21
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AU2805697A (en) 1997-11-12

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