CN1247745A - Anticarcinogen and its preparation - Google Patents
Anticarcinogen and its preparation Download PDFInfo
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- CN1247745A CN1247745A CN 98112624 CN98112624A CN1247745A CN 1247745 A CN1247745 A CN 1247745A CN 98112624 CN98112624 CN 98112624 CN 98112624 A CN98112624 A CN 98112624A CN 1247745 A CN1247745 A CN 1247745A
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Abstract
The Chinese medicine anticarcinogen mainly consists of 37 Chinese medicinal materials including bezoard, musk, bear bile, centipede, Bombyx Batryticatus, etc. and its preparation includes the steps of decoction, disinfection and concentration into granule. The present invention has the features of high cure effect and high pain relieving effect, can reduce or even eliminate canceration tissue, raise the life quality of late-stage cancer patient and prolong the survical period of late-stage cancer patient.
Description
The present invention relates to a kind of anticarcinogen and preparation method thereof.
Cancer is still one of persistent ailment of not capturing in the whole world so far, its therapeutic modality is aspect modern medicine, the Comprehensive Treatment of operative treatment, chemotherapy, radiotherapy, immunization therapy or above method etc. is arranged, operative treatment only is suitable for early, mid-term the cancer patient, and relapse rate height is though chemotherapy, radiotherapy have the effect of kill cancer cell, also killed simultaneously a large amount of normal cells, very big to injury of human, toxic and side effects is big, makes patient with advanced cancer be difficult to adapt to.Immunization therapy, effect is undesirable and cost an arm and a leg, and people are difficult to bear.
The object of the present invention is to provide a kind of safely, have no side effect, short treating period, instant effect, low-cost anticarcinogen and preparation method thereof.
The objective of the invention is to realize in the following manner: a kind of anticarcinogen, it mainly is by (by weight percentage) Calculus Bovis 0.03-0.1; Moschus 0.03-0.1; Radix Ginseng 1.7-3.5; Radix Astragali 2-6; Poria 2-4; Rhizoma Coptidis 2-4; Radix Et Rhizoma Rhei 1-3; Scolopendra 0.3-1.5; Bombyx Batryticatus 0.3-1.5; graceful jessamine herb 0.002-0.003; Gekko Swinhonis 0.3-1.5; Rhizoma Imperatae 1-3; Herba Agrimoniae 1-3; Cordyceps 0.6-2.3; Radix Rehmanniae Preparata 3-5; Venenum Bufonis 0.003-0.005; Margarita 0.3-1.7 Nidus Vespae 0.3-1.5; Semen Strychni 0.03-0.1; Gypsum Fibrosum 5-10; Squama Manis 0.3-1.5; Herba Hedyotidis Diffusae 3-5; Herba Scutellariae Barbatae 2-4; Fel Ursi 0.3-1.5; Semen Benincasae 1-3; Radix Notoginseng 0.3-1.7; Herba Houttuyniae 2-4; Radix Ophiopogonis 2-6; Radix Asparagi 2-4; Sal Ammoniacus 0.03-0.07; Pseudobulbus Cremastrae Seu Pleiones 0.3-0.7; Dioscorea bulbifera L. 2-3; Semen Ignatii 0.003-0.01; Radix Glycyrrhizae 2-3; Semen phaseoli radiati 8-10 Radix Adenophorae Trachelioidis 4-6; Mylabris 0.003-0.01; Rhizoma amorphophalli 1-3; Coriolous Dersicolor (Fr.) Quel 0.3-1 forms.The percentage by weight of each component thing is preferably: Calculus Bovis 0.041; Moschus 0.041; Radix Ginseng 3.46; the Radix Astragali 5.69; Poria 3.69; Rhizoma Coptidis 3.69; Radix Et Rhizoma Rhei 2.46; Scolopendra 1.23; Bombyx Batryticatus 1.23; graceful jessamine herb 0.003; Gekko Swinhonis 1.23; Rhizoma Imperatae 2.46; Herba Agrimoniae 2.46; Cordyceps 2.05; Venenum Bufonis 0.005; Radix Rehmanniae Preparata 5; Margarita 1.64; Nidus Vespae 1.23; Semen Strychni 0.041; Gypsum Fibrosum 10; Squama Manis 1.23; Herba Hedyotidis Diffusae 4.95; Herba Scutellariae Barbatae 4; Fel Ursi 1.23; Semen Benincasae 2.46; Radix Notoginseng 1.23; Herba Houttuyniae 3.69; Radix Ophiopogonis 4.69; Radix Asparagi 3.69; Sal Ammoniacus 0.041; Pseudobulbus Cremastrae Seu Pleiones 0.41; Dioscorea bulbifera L. 3; Semen Ignatii 0.009; Radix Glycyrrhizae 2.35; Semen phaseoli radiati 10 Radix Adenophorae Trachelioidis 6; Mylabris 0.009; Rhizoma amorphophalli 2.46; Coriolous Dersicolor (Fr.) Quel 0.9.The preparation method of above-mentioned anticarcinogen is: a. at first takes by weighing the each component thing by above-mentioned percentage by weight, shred each crude drug standby respectively, b. then Scolopendra, Bombyx Batryticatus, graceful jessamine herb, Gekko Swinhonis, Venenum Bufonis, Nidus Vespae, Semen Strychni, Sal Ammoniacus, Pseudobulbus Cremastrae Seu Pleiones, Dioscorea bulbifera L., Semen Ignatii, Mylabris, Rhizoma amorphophalli, Semen phaseoli radiati, Radix Glycyrrhizae, Radix Adenophorae Trachelioidis, Gypsum Fibrosum, mixing and water adding being covered powder decocts, filtered in 20-60 minute after boiling, reserved filtrate is standby, medicinal residues are added water again cross the powder back of boiling and dropped into the Radix Et Rhizoma Rhei digestion 3-10 minute after 15-55 minute, merge filtrate for later use twice; C. Radix Ginseng, the Radix Astragali, Poria, Rhizoma Coptidis, Rhizoma Imperatae, Herba Agrimoniae, Cordyceps, Radix Rehmanniae Preparata, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Semen Benincasae, Radix Notoginseng, Herba Houttuyniae, Radix Ophiopogonis, Radix Asparagi, Coriolous Dersicolor (Fr.) Quel, Margarita, Squama Manis mixing and water adding being crossed powder decocts, back filtration in 10-60 minute reserved filtrate boils, medicinal residues decoct with water again, boiled back 10-60 minute, and merged filtrate for later use twice; D. get each 150 Bo of twice merging filtrate of b, c and open, add Calculus Bovis, Moschus, Fel Ursi decoction, be concentrated into 250 milliliters and get final product; Behind concentrated solution bottling, gland, 125 ℃ of 30 minutes autoclavings.Concentrated solution can also be condensed into the thick paste shape, add the white sugar mixing and cross 10 mesh sieves, put into the drying machine inner drying, splitting behind the weighing, enclosed package.
The main chemical of the each component of this anticarcinogen is: Calculus Bovis: cholic acid, bilirubin, cholesterol, sodium, calcium, magnesium etc.; Moschus: muscone, fatty acid, cholesterol; Radix Ginseng: the Stem and leaf of Radix Ginseng soap is guarded against, Radix Ginseng medicine flower glycoside; The Radix Astragali: astragalus polysaccharides; Coriolous Dersicolor (Fr.) Quel: polysaccharide, mannose; Poria: pachyman; Rhizoma Coptidis: multiple alkaloids such as berberine, palm leaf coculine; Scolopendra: H-subst, cholesterol, tyrosine; Bombyx Batryticatus: organize amine; Gekko Swinhonis: organize amine; Graceful jessamine herb: indoles alkaloid; Rhizoma Imperatae: fructose, organic acid, Anemonin; Herba Agrimoniae: agrimonine, flavonoid glycoside, vitamin C, K; Cordyceps: crude protein, cordycepic acid, cordycepin; Venenum Bufonis: toadpoison, interior lipid, sterols; Margarita: calcium carbonate; Nidus Vespae: the histamine of bee venom; Semen Strychni: contain various alkaloids, strychnines such as strychnine; Gypsum Fibrosum: CaSo42H2O, magnesium, ferrum; Squama Manis: contain protein; Herba Hedyotidis Diffusae: contain maloic acid, oleanolic acid etc.; Herba Scutellariae Barbatae: contain alkaloid, flavonoid; Fel Ursi: cholesterol, bile pigments, slaine; Sal Ammoniacus: ammonium chloride (NH4CL); Pseudobulbus Cremastrae Seu Pleiones: colchicine; Dioscorea bulbifera L.: dioscin, diosbulbin A, B, C; Semen Ignatii: alkaloid; Mylabris: cantharidin, fat, formic acid; Rhizoma amorphophalli: mannan.Its anticancer pharmacological action and mechanism are: 1). directly suppress or kill cancerous cell: in the prescription: Rhizoma Coptidis, Herba Agrimoniae, Cordyceps, Herba Hedyotidis Diffusae, Gekko Swinhonis, Venenum Bufonis, Nidus Vespae, Semen Strychni, Sal Ammoniacus, Pseudobulbus Cremastrae Seu Pleiones, graceful jessamine herb, Dioscorea bulbifera L., Mylabris, Rhizoma amorphophalli, Radix Ginseng, Scolopendra confirm the effect that direct inhibition all arranged or kill cancerous cell through zoopery.2). change the surface charge of cell membrane.Semen Strychni in the prescription makes cancerous cell skin covering of the surface electric charge transform to normal cell through zoopery.3). to cancerous cell DNA, proteometabolic influence.Show that through zoopery cantharidin can suppress DNA and proteinic synthetic in the prescription, and the performance antitumaous effect.4). the human body immunity improving function: Radix Ginseng, the Radix Astragali, Radix Asparagi, Radix Ophiopogonis, Cordyceps, Radix Rehmanniae Preparata confirm through zoopery in the prescription, the reticuloendothelial system of promotion function is arranged, promote lymhocyte transformation rate, strengthen anti-cancer ability, and immunologic function is had dual regulation.The reduction gradually that immunologic function is hyperfunction, the then rising of immunologic hypofunction.5). improve body physiological function.The Radix Ginseng Radix Astragali, Radix Ophiopogonis, Radix Asparagi, Radix Glycyrrhizae can strengthen the physiological function that hypophysis one adrenal cortex function hemopoietic function of bone marrow helps disorder in the tumor body in the prescription, with the recovery of interior environment disruption, make the long rising of body hematochrome and hemocyte.By clinical observation, discovery can improve liver function, and making changes the decline of chlorine enzyme, and total bilirubin descends, and improves renal function, and the urine amount is increased, and creatinine and blood urea nitrogen descend.It has 1). the effect of heat-clearing and toxic substances removing: in the prescription: Calculus Bovis, Fel Ursi, Semen phaseoli radiati, the Radix Astragali, Rhizoma Coptidis, Herba Scutellariae Barbatae, Herba Houttuyniae, Gypsum Fibrosum have the effect of heat-clearing and toxic substances removing.2). the hard masses softening and resolving effect: Dioscorea bulbifera L., Venenum Bufonis, Nidus Vespae, Pseudobulbus Cremastrae Seu Pleiones all have the hard masses softening and resolving effect.3). the effect of blood circulation promoting and blood stasis dispelling: Gelsemium elegans Benth., Radix Notoginseng, Scolopendra have the effect of blood circulation promoting and blood stasis dispelling.4). the effect of the body resistance strengthening and constitution consolidating: Radix Ginseng, the Radix Astragali, Cordyceps, Radix Rehmanniae Preparata, Coriolous Dersicolor (Fr.) Quel all have the effect of the body resistance strengthening and constitution consolidating.It can be killed or anticancer, again can the enhancing human body immunity function, and be a kind of PTS that is hopeful to capture cancer most.
Anticarcinogen of the present invention, through doing " acute toxicity test ", confirm this medicine safety, have no side effect, confirm through long-term experiment, use it in the treatment, terminal cancer, the curative effect that has surpassed present domestic other treatment cancer method is through the Hunan Province academy of traditional Chinese medicine, Hunan Medical University, Hunan Province tumour hospital, experts such as the Hunan Province association for science and technology appraise the clinical efficacy of 93 routine terminal cancer through discussion, and cure rate reaches 16%, the cancer piece dwindle high this 62%, effective percentage this 92%, the analgesia rate reaches 98%, this medical instrument has short treating period, instant effect, the curative effect height, the characteristics that the analgesia rate is high, can dwindle or eliminate the cancer piece, the effect that can improve patient with advanced cancer quality life cycle and prolong life cycle.
Below in conjunction with embodiment the present invention is described in further detail: get Calculus Bovis 0.041 gram; Moschus 0.041 gram; Radix Ginseng 3.46 grams; the Radix Astragali 5.69 grams; Poria 3.69 grams; Rhizoma Coptidis 3.69 grams; Radix Et Rhizoma Rhei 2.46 grams; Scolopendra 1.23 grams; Bombyx Batryticatus 1.23 grams; graceful jessamine herb 0.003 gram; Gekko Swinhonis 1.23 grams; Rhizoma Imperatae 2.46 grams; Herba Agrimoniae 2.46 grams; Cordyceps 2.05 grams; Radix Rehmanniae Preparata 5 grams; Venenum Bufonis 0.005 gram; Margarita 1.64 grams; Nidus Vespae 1.23 grams; Semen Strychni 0.041 gram; Gypsum Fibrosum 10 grams; Squama Manis 1.23 grams; Herba Hedyotidis Diffusae 4.95 grams; Herba Scutellariae Barbatae 4 grams; Fel Ursi 1.23 grams; Semen Benincasae 2.46 grams; Radix Notoginseng 1.23 grams; Herba Houttuyniae 3.69 grams; restrain Radix Ophiopogonis 4.69; Radix Asparagi 3.69 grams; Sal Ammoniacus 0.041 gram; Pseudobulbus Cremastrae Seu Pleiones 0.41 gram; Dioscorea bulbifera L. 3 grams; Semen Ignatii 0.009 gram; Radix Glycyrrhizae 2.35 grams; Semen phaseoli radiati 10 grams; shepherd's purse 6 grams; Mylabris 0.009 gram; Rhizoma amorphophalli 2.46 grams; Coriolous Dersicolor (Fr.) Quel 0.9 gram is standby.
The first step: the medicine chopping, earlier with the crude drug chopping, processing helps the decoction of medicine into about about 2 centimetres sizes.
Second step: remove the toxicity of drug toxicity, keep its anticancer property of medicine.Scolopendra, Bombyx Batryticatus, Gelsemium elegans Benth., Gekko Swinhonis, Venenum Bufonis, Nidus Vespae, Semen Strychni, sand, Pseudobulbus Cremastrae Seu Pleiones, Dioscorea bulbifera L., Semen Ignatii, Mylabris, Rhizoma amorphophalli covered the decoction of medicine face by the equal portions mixing and water adding of prescription percentage ratio, the filtration in back 40 minutes of boiling, reserved filtrate is standby, medicinal residues add water again and cross powder, dropped into the Radix Et Rhizoma Rhei digestion 5 minutes after boiling back 35 minutes, merge filtrate twice, (illustrate: so Gypsum Fibrosum, sand, Semen phaseoli radiati, shepherd's purse late-maturing, Radix Glycyrrhizae are antidote to get 150 milliliters, by the lengthening decocting time, to remove the toxicity of medicine.Then keep its property of medicine).
The 3rd step: Radix Ginseng, the Radix Astragali, Poria, Rhizoma Coptidis, Rhizoma Imperatae, Herba Agrimoniae, Cordyceps, Radix Rehmanniae Preparata, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Semen Benincasae, Radix Notoginseng, Herba Houttuyniae, Radix Ophiopogonis, Radix Asparagi, Coriolous Dersicolor (Fr.) Quel, Margarita, Squama Manis are got medicine-feeding and are added water cover and cross the medicine face and decoct, the filtration in back 30 minutes of boiling, reserved filtrate is standby, medicinal residues add water again and cross powder, boiled back 30 minutes, filter reserved filtrate, merge filtrate twice, get 150 milliliters.
The 4th step: second step decoct 150 milliliters are added the 3rd step decoct 150 milliliters, add up to 300 milliliters, add Calculus Bovis, Moschus, Fel Ursi, be concentrated into 250 milliliters and get final product by the decoction of prescription percentage ratio part.
The 5th step: behind bottling, the gland, 125 ℃, 30 minutes autoclavings.Also decoct filtrate can be heated and be condensed into the thick paste shape, add white sugar, mixing is crossed 10 mesh sieves, and granule is put into common drying machine, cold drying, and weighing claims every bag of 10g splitting, is equivalent to the airtight preservation of crude drug in whole 80g.Usage: three times on the one, each one bag, boiled water is taken after mixing it with water.Attached model case is as follows: 1. old and 42 years old cadre of Xiangtan City diet company of liter man
Shift postoperative rectal cancer whole body many places
Bladder, the transfer of bone many places 1 year appears in the recurrence in 3 years of patient's postoperative rectal cancer.In in May, 1989 because of suffering from rectal cancer at Central Hospital of Xiangtan City's row " rectal carcinoma radical ", right lower extremity pain appears in postoperative 2 years in November, 1991, simultaneously with hematuria, hypogastric region enclosed mass, go tumour hospital of Zhongshan Medical Univ. row CT examination to be diagnosed as " postoperative rectal cancer; shift bladder bone many places " on November 29th, 92 and find that posterior wall of urinary bladder has two egg size lumps, the right ischium joint of left side pubis rumpbone place many places bone shifts right lower extremity sharp ache, dysbasia.Right lower extremity pain relief after beginning to take this anticarcinogen and took medicine 10 days in August, 1992 can be walked, and hematuria disappears, and spirit is clearly better, (60 days) right lower extremity total pain relief after 2 courses of treatment of taking medicine, and hematuria disappears, physical recovery health.In on November 4th, 92 in Hunan Province tumour hospital CT examination, the complete obiteration of bladder lump, the complete obiteration of bone metastasis, disease recovery from illness reaches fully and alleviates.2. Zhu elder generation side man 59 years old Hunan Province road county procuratorate late gastric cancer patient was because of carrying out property dysphagia 10 months, increased the weight of 3 months, begin to occur dysphagia March nineteen ninety, feed has sense of obstruction, August 4 nineteen ninety is at road, Hunan Province county people's hospital row fibergastroscopy, be diagnosed as " stomach carcinoma of gastric cardia ", after Hunan Medical University's pathologic finding turns out to be " poorly differentiated adenocarcinoma cancer ", the about 1.0 * 0.8cm of lump size
2, through Guilin how tame large hospitals such as 181 hospitals, Hunan Province tumour hospital, Affiliated Hospital No. 1, Hunan Medical College control invalid.In in JIUYUE, 1991 gastroscopy, lump increases to 3.5 * 3.5cm
2, feed is difficulty very, only can take food stream juice retrosternal pain unbearably, and it is weak to become thin, the feed vomiting.Begin to take a course of treatment of this anticarcinogen (after 30 days) in October, 1991, symptom is obviously improved, and can advance full diet, and vomiting disappears, and every meal can be eaten four liang of cooked rice.At Hunan steel worker's hospital check gastroscope, cancer piece complete obiteration in the stomach cardia, the rarely seen one about 1.0 * 1.5cm of lump portion
2Size is rotten to the corn, and pathological biopsy is not seen cancerous cell, treats two courses of treatment, and patient returns to one's perfect health.3. old letter is asked man's Kaohsiung City, Taiwan Province merchant's gastric cancer hepatic metastases in 57 years old
Because of epigastrium pain, companion's vomiting 2 months is carried out gastroscope, ultrasound diagnosis in May, 1993 in Kaohsiung City, Taiwan Province hospital, be diagnosed as " gastric cancer hepatic metastases ", the row exploratory laparotomy, seeing has a plurality of metastasis in the liver, lymphonodi coeliaci extensively shifts, the row " gastric lump local excision adds gastrojejunostomy ", postoperative, because of body constitution bad, fail to carry out chemotherapy, postoperative has a plurality of metastasis, the about 3.4 * 3.6cm of maximum lump on the July 14th, 1993 of first hospital B ultrasonic check in the Xiamen City in the liver
2Chief Liu of Nikkei Xiamen City Siming District health bureau introduction began to take this anticarcinogen July 16 in 1993, behind the two weeks, the epigastrium pain relief, appetite is improved, weight increase, spirit takes a turn for the better, in Xiamen City Siming District hospital B ultrasonic check on August 5th, 1993, the tuberosity lump dwindles in the liver, after four courses of treatment of taking medicine (4 months), various symptom complete obiterations, health recovers normally fully, checks B ultrasonic, the complete obiteration of gastric lump on April 14th, 1994 in Tainan City hospital, obviously dwindle in the liver in the liver, obviously prolonged patient's life cycle.4. shop, the plate pool, city, yellow damp merit 60 years old xiangtan, hunan province of man vehicle repairing factory retired worker carcinoma of head of pancreas
Deepened 1 month because of carrying out property jaundice, patient begins to occur inappetence in July, 1992, and jaundice is deepened gradually, feel sick, vomit, detest oil, left upper abdomen pain occurs, be in hospital in Centre Hospital, Xiangtan City, Hunan Prov. in August, 1992, row CT, ultrasound diagnosis find that head of pancreas has about a 3 * 4cm
2The size lump, liver function test, total bilirubin reaches 700umg/l, is diagnosed as " carcinoma of head of pancreas ", due to illness the people refuse the operation, on October 8th, 1992 begin to take this anticarcinogen (before taking, ultrasound diagnosis, the head of pancreas lump is 4.7 * 4.9cm
2, potter's clay color stool, it is golden yellow that the whole skin mucosa is, yellow urine.After taking medicine 15 days, patient's whole body jaundice fades away, liver function test, and total bilirubin drops to 120umg/l, and check B ultrasonic head of pancreas lump is reduced into 2.7 * 2.8cm
2, appetite increases, and spirit is clearly better, and takes medicine 30 days (after the course of treatment), and it is normal that appetite is recovered, and whole body mucosa jaundice disappears substantially, and total bilirubin is 50umg/l, October 28 in 1992 CT of Nikkei People's Hospital, Hunan Prov., B ultrasonic check, the complete obiteration of head of pancreas lump.Existing patient is still alive, and health returns to one's perfect health, and survival has reached 6 years 01 months.5. to new flourish woman 39 years old changde, hunan province workman of city HONGGUANG instrument plant
Behind the right liver, left liver frontal lobe constitutional massive hepatocarcinoma
Patient in March, 1992 begin to occur right hepatalgia, feel sick, vomiting, appetite be poor, weight loss.In in May, 1992 state of an illness increase the weight of, go the row ultrasound diagnosis of changde, hunan province city first hospital, be diagnosed as " huge hepatocarcinoma of left and right sides leaf " companion jaundice, ascites, the appetite extreme difference, be unable to leave the bed, the hepatic region has an intense pain, the doctor of this institute thinks: this patient can not surpass 15 days life cycle, patient discharge preparation funeral affairs, and patient embraces and producing a gleam of hope and look for Zhu Shaoyi doctor to seek medical advice on June 10th, 1992, take this anticarcinogen after 7 days, the upper right abdomen pain of patient obviously alleviates, and appetite increases, and feels sick, symptoms of emesis alleviates, can out-of-bed activity, take medicine after 2 courses of treatment (60 days), hepatalgia disappears, and it is normal that appetite is recovered, every meal can be eaten three to four liang in rice, lump dwindles in the check B ultrasonic liver, and AFP turns out cloudy, and patient takes this anticarcinogen after three courses of treatment altogether, health recovers rehabilitation fully, life can be taken care of oneself, and after 2 years, patient died from heart attack death in 1994.6. 46 years old worker of the motor transport corps of Xiangtan Iron ﹠ Steel Co. Hunan Prov. of Hu Guangzhong man
The nasopharyngeal carcinoma hepatic metastases, companion's hepatic coma
Patient is " nasopharyngeal carcinoma " March nineteen ninety in the true rash of Hunan Province tumour hospital, bleeds in the nostril, symptoms such as headache, giddy, and after two courses of treatment, because patient's body constitution is poor, leukocyte is reduced to 2000/mm in Hunan Province tumour hospital chemotherapy
3So, stop chemotherapy, change the treatment of Xiangtan Iron and Steel worker's hospital after leaving hospital over to, right hepatalgia appears in patient July 12 nineteen ninety, appetite obviously descends, and becomes thin, and engenders jaundice, ascites, through ultrasound diagnosis, find liver diffusivity lump, in nineteen ninety JIUYUE obnubilation appears, the doctor of this hospital is diagnosed as " nasopharyngeal carcinoma hepatic metastases, hepatic coma ".Only be about seven days life cycle.This moment, families of patients found Zhu Shaoyi doctor to require to take this anticarcinogen.At that time, patient's stupor, medicine can only inject in stomach tube, after taking medicine 7 days, it is normal that patient's mind is recovered, and jaundice alleviates, hepatalgia alleviates, patient recovers normally substantially after taking medicine 60 days, and the whole body jaundice disappears, and hepatalgia is alleviated, it is normal that appetite is recovered, lump disappears in the liver, and ascites disappears, and it is normal that every chemical examination all recovers.In B ultrasonic check on April 16th, 1991 liver, the liver size shape is normal fully, the disease recovery from illness.7. all abundant clear male 54 years old xiangtan, hunan province city Fine Chemical Works cadres
Left side liver massive type primary hepatocarcinoma
Patient is because of hepatalgia January, appetite reduces, and the property of gradually going is become thin, and goes the row CT of Hunan Province tumour hospital, B ultrasonic, AFT to check on the 24th in JIUYUE in 1992, be diagnosed as " left hepatic region piece type primary hepatocarcinoma ", 26, Xiangtan No. 1 People's Hospital's B ultrasonic of 92 on JIUYUE show: left liver 8 * 9.7cm
2Lump, companion's jaundice, hepatalgia is violent, looks for Zhu Shaoyi doctor to seek medical advice on October 7th, 1992, and body is looked into the whole skin yellow sclera, and liver 5cm place under right rib can touch, and tenderness is arranged.Check B ultrasonic before taking medicine on October 10th, 92, lump increases to 12.8 * 8cm in the liver
2Lump increases 3cm in the two weeks, begins to take this anticarcinogen after 30 days on October 10th, 92, and hepatalgia disappears, and the whole body jaundice disappears, and appetite increases.Check at the CT of Hunan Province tumour hospital for 92 November 17 days, lump 8.9 * 13.8cm2 size in the left liver, and 40 day time only increased 1cm, had obviously suppressed growth of cancer cells.After taking medicine 3 months, patient body returns to one's perfect health, and can recover operate as normal, and in the CT of Annex II hospital of Nikkei Hunan Province medical university check February 17 in 1993, lump is contracted to 5 * 6cm in the left liver
2Size, evident in efficacy.This patient is dead in nineteen ninety-five December recurrence, prolongs 3 years 02 months life cycle.8. ready-made clothes literary composition man 70 years old xiangtan, hunan province worker of city shipping company
Gastric cancer is accompanied pyloric obstruction late period
Because of epigastrium pain, feel sick, vomitted 4 months, can not take food 7 days, epigastrium pain appears in the patient in January, 1992, feel sick, symptom such as vomiting, through Xiang Tan central hospital fibergastroscopy, be diagnosed as gastric cancer, stomach pyloric obstruction, pathological section confirm " the low adenocarcinoma of dividing of stomach ".Invalid through how tame hospitalizes such as Xiang Tan central hospital, Xiangtan City first hospitals, patient can not take food fully on March 20th, 92, skeletonize, was unable to leave the bed, and not feed in existing seven days only depending on transfusion to keep.Family members found Zhu Shaoyi doctor to seek medical advice on March 21st, 92, looked into patient's body constitution extreme difference, and whole body skeletonize, epigastrium can be visited and see the big lump of an about fist, and tenderness is arranged.Patient's spirit is clearly better after taking medicine 7 days, gradually can influent stream juice diet, and patient can advance 3 liang of noodles of semi-fluid after 15 days, can out-of-bed activity.The epigastrium enclosed mass dwindles gradually, the epigastrium pain relief.Taking medicine, check stomach hinge mirror was clearly better before 4 months after January, and pathological section confirms stomach cancer cell degeneration, necrosis.This patient only took medicine 30 days, and physical recovery is very fast, confirmed that through pathological section the cancerous cell degeneration necrosis illustrates that this anticarcinogen has the effect of kill cancer cell really, and this patient prolongs life cycle and reaches 1 year 02 months in death in June, 93.9. Peng Baohua man 56 years old xiangtan, hunan province cadre of city Bearing Factory
Left side liver massive type primary hepatocarcinoma
The patient occurred right hepatalgia on the 26th in JIUYUE in 1992, and appetite descends, and whole skin jaundice, Pruritus are felt sick, symptom such as vomiting.Colored B ultrasonic shows in an attached hospital of Nikkei Hunan Province medical university October 7 in 1992: right liver posterior lobe is visited and lump 97 * 97 * 83cm
3, AFT) 500ug/ml is diagnosed as " right liver massive type primary hepatocarcinoma ".Think that this patient can't undergo surgery, treatments such as chemotherapy, life cycle is difficult above three months.This family numbers of patients finds Zhu Shaoyi doctor, this anticarcinogen is taken in requirement, begin to take this medicine after 1 month on October 8th, 92, the right hepatalgia of patient disappears, and the whole skin xanthochromia disappears, appetite increases, feel sick, transference cure such as vomiting, various symptom complete obiterations after taking medicine 60 days, weight increase 10Kg, 92 on Decembers check in 26, B ultrasonic, lump is contracted to 8 * 6cm in the liver
2Went to an attached hospital of Hunan Medical University after taking medicine 4 months, swollen 43 * 43 * 41cm that is contracted in the right liver
3, patient returns to one's perfect health.So far have many doctors of hospital to suspect that this patient is not a hepatocarcinoma, diagnosis may be mistaken diagnosis before thinking, patient continues treatment again, and this patient to 1996 state of an illness in year November changes suddenly, occurs that lump increases to 12 * 13 * 10cm rapidly in jaundice, ascites, the right liver
3, died from Xiangtan City first hospital's oncology in 1996.Prolong 4 years 02 months life cycle, might cure fully if this patient continues treatment at that time.
Claims (4)
1. an anticarcinogen is characterized in that it is mainly by (by weight percentage) Calculus Bovis 0.03-0.1; Moschus 0.03-0.1; Radix Ginseng 1.7-3.5; Radix Astragali 2-6; Poria 2-4; Rhizoma Coptidis 2-4; Radix Et Rhizoma Rhei 1-3; Scolopendra 0.3-1.5; Bombyx Batryticatus 0.3-1.5; graceful jessamine herb 0.002-0.003; Gekko Swinhonis 0.3-1.5; Rhizoma Imperatae 1-3; Herba Agrimoniae 1-3; Cordyceps 0.6-2.3; Radix Rehmanniae Preparata 3-5; Venenum Bufonis 0.003-0.005; Margarita 0.3-1.7 Nidus Vespae 0.3-1.5; Semen Strychni 0.03-0.1; Gypsum Fibrosum 5-10; Squama Manis 0.3-1.5; Herba Hedyotidis Diffusae 3-5; Herba Scutellariae Barbatae 2-4; Fel Ursi 0.3-1.5; Semen Benincasae 1-3; Radix Notoginseng 0.3-1.7; Herba Houttuyniae 2-4; Radix Ophiopogonis 2-6; Radix Asparagi 2-4; Sal Ammoniacus 0.03-0.07; Pseudobulbus Cremastrae Seu Pleiones 0.3-0.7; Dioscorea bulbifera L. 2-3; Semen Ignatii 0.003-0.01; Radix Glycyrrhizae 2-3; Semen phaseoli radiati 8-10 Radix Adenophorae Trachelioidis 4-6; Mylabris 0.003-0.01; Rhizoma amorphophalli 1-3; Coriolous Dersicolor (Fr.) Quel 0.3-1 forms.
2. according to the described anticarcinogen of claim 1, it is characterized in that: the percentage by weight of each component thing is: Calculus Bovis 0.041; Moschus 0.041; Radix Ginseng 3.46; the Radix Astragali 5.69; Poria 3.69; Rhizoma Coptidis 3.69; Radix Et Rhizoma Rhei 2.46; Scolopendra 1.23; Bombyx Batryticatus 1.23; graceful jessamine herb 0.003; Gekko Swinhonis 1.23; Rhizoma Imperatae 2.46; Herba Agrimoniae 2.46; Cordyceps 2.05; Radix Rehmanniae Preparata 5; Venenum Bufonis 0.005; Margarita 1.64; Nidus Vespae 1.23; Semen Strychni 0.041; Gypsum Fibrosum 10; Squama Manis 1.23; Herba Hedyotidis Diffusae 4.95; Herba Scutellariae Barbatae 4; Fel Ursi 1.23; Semen Benincasae 2.46; Radix Notoginseng 1.23; Herba Houttuyniae 3.69; Radix Ophiopogonis 4.69; Radix Asparagi 3.69; Sal Ammoniacus 0.041; Pseudobulbus Cremastrae Seu Pleiones 0.41; Dioscorea bulbifera L. 3; Semen Ignatii 0.009; Radix Glycyrrhizae 2.35; Semen phaseoli radiati 10 Radix Adenophorae Trachelioidis 6; Mylabris 0.009; Rhizoma amorphophalli 2.46; Coriolous Dersicolor (Fr.) Quel 0.9.
3. the preparation method of an anticarcinogen as claimed in claim 1, it is characterized in that: a. at first takes by weighing the each component thing by the described percentage by weight of claim 1, shred each crude drug standby respectively, b. then with Scolopendra, Bombyx Batryticatus, graceful jessamine herb, Gekko Swinhonis, Venenum Bufonis, Nidus Vespae, Semen Strychni, Sal Ammoniacus, Pseudobulbus Cremastrae Seu Pleiones, Dioscorea bulbifera L., Semen Ignatii, Mylabris, Rhizoma amorphophalli, Semen phaseoli radiati, Radix Glycyrrhizae Radix Adenophorae Trachelioidis, the Gypsum Fibrosum mixing and water adding covered powder and decocts: filtered in 20-60 minute the back of boiling, reserved filtrate is standby, medicinal residues are added water again cross the powder back of boiling and dropped into the Radix Et Rhizoma Rhei digestion 3-10 minute after 15-55 minute, merge filtrate for later use twice; C. Radix Ginseng, the Radix Astragali, Poria, Rhizoma Coptidis, Rhizoma Imperatae, Herba Agrimoniae, Cordyceps, Radix Rehmanniae Preparata, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Semen Benincasae, Radix Notoginseng, Herba Houttuyniae, Radix Ophiopogonis, Radix Asparagi, Coriolous Dersicolor (Fr.) Quel, Margarita, Squama Manis mixing and water adding being crossed powder decocts, back filtration in 10-60 minute reserved filtrate boils, medicinal residues decoct with water again, boiled back 10-60 minute, filter reserved filtrate, merge filtrate for later use twice; D. get each 150 milliliter of twice merging filtrate of b, c, add Calculus Bovis, Moschus, Fel Ursi decoction, be concentrated into 250 milliliters and get final product; Behind concentrated solution bottling, gland, 125 ℃ of 30 minutes autoclavings.
4. the preparation method of anticarcinogen according to claim 3 is characterized in that: concentrated solution is condensed into the thick paste shape, adds the white sugar mixing and cross 10 mesh sieves, put into the drying machine inner drying, splitting behind the weighing, enclosed package.
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| WO2002094298A1 (en) * | 2001-05-25 | 2002-11-28 | Yongzhong Li | Traditional chinese medicine for treatment and prevention of cancer |
| CN102357202A (en) * | 2011-10-17 | 2012-02-22 | 南京中医药大学 | Traditional Chinese medicine cancer toxin prescription for treating liver cancer and application thereof in pharmacy |
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| CN103100047A (en) * | 2013-01-17 | 2013-05-15 | 郭玉玲 | Traditional Chinese medicine composition for treating gastric cancer and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2002094298A1 (en) * | 2001-05-25 | 2002-11-28 | Yongzhong Li | Traditional chinese medicine for treatment and prevention of cancer |
| CN102357202A (en) * | 2011-10-17 | 2012-02-22 | 南京中医药大学 | Traditional Chinese medicine cancer toxin prescription for treating liver cancer and application thereof in pharmacy |
| CN102357202B (en) * | 2011-10-17 | 2014-04-16 | 南京中医药大学 | Traditional Chinese medicine cancer toxin prescription for treating liver cancer and application thereof in pharmacy |
| CN103071116A (en) * | 2013-01-17 | 2013-05-01 | 张玉霞 | Traditional Chinese medicine preparation for treating esophagus cancer and preparation method thereof |
| CN103100047A (en) * | 2013-01-17 | 2013-05-15 | 郭玉玲 | Traditional Chinese medicine composition for treating gastric cancer and preparation method thereof |
| CN103071116B (en) * | 2013-01-17 | 2014-06-04 | 张玉霞 | Traditional Chinese medicine preparation for treating esophagus cancer and preparation method thereof |
| CN103100047B (en) * | 2013-01-17 | 2014-09-24 | 青岛市肿瘤医院 | Traditional Chinese medicine composition for treating gastric cancer and preparation method thereof |
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| CN104305212A (en) * | 2014-09-17 | 2015-01-28 | 姚大军 | Food for treating cancer and preparation method of food |
| CN104324091A (en) * | 2014-11-11 | 2015-02-04 | 蒋丽红 | Traditional Chinese medicine formula for treating rectal cancer |
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