CN104027447B - A kind of Chinese medicine of Therapeutic cancer - Google Patents
A kind of Chinese medicine of Therapeutic cancer Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine of Therapeutic cancer.It is characterized in that by the medical material of following weight parts formulated: Radix Angelicae Sinensis 15-30 part, Herba Artemisiae Annuae 15-30 part, Radix Cirsii Japonici 15-30 part, Nidus Vespae 10-20 part, Radix Astragali 15-30 part, Semen Strychni (processed) 15-20 part, Resina Toxicodendri 10-15 part processed, Fructus Hippophae 15-25 part processed, Sal Nitri 20-30 part, Herba Agrimoniae 20-30 part, Herba Urticae Cannabinae 15-30 part, Fructus Aurantii 25-40 part.Chinese medicine of the present invention does not almost have toxicity to normal cell, only than under the concentration using anticancer dosage to exceed nearly a hundred times, just toxic to normal cell.Fill up existing reliable anticancer effect, again without the cancer therapy drug blank of normal cell damage.It is wide that the present invention has medicine source, cheap and easy to get, make simple, and the suitability is wide, the advantages such as medical expense is low.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine of Therapeutic cancer.
Background technology
Tumor is a great problem of world today's medical science tackling key problem, and the health and lives safety of the mankind in serious threat.In the world cancer year death toll nearly ten million, China about has people up to a million to die from malignant tumor every year.Unclear yet at present to the etiology and pathogenesis of tumor, but normal histiocyte is under certain unfavorable factor or certain environmental conditions, and producer sudden change has occurred that paraplasm is tumor this point and builds consensus.
At present, Modern medical therapy malignant tumor method is more, but there is no specific treatment.Gene therapy can be the mankind and captures malignant tumor and open up new channel, but cost is high, expense is expensive, common people can bear absolutely not, there is major defect as the method such as radiotherapy, chemotherapy in other, lacks specificity, mostly while tumor cell is killed and wounded, normal histiocyte is is also killed and wounded, and shortens life cycle to making many patients because of serious toxicity reaction.
Traditional medicine think tumor be " positive QI-insufficiency, heresy and contain, stasis forms.", Chinese traditional treatment cancer is divided into righting and eliminating evil two aspects.Namely righting by regulating autoimmune function, reaches anticancer object; Eliminating evil, directly tackle focus, Tumor suppression grows.The Chinese medicine of some treatment malignant tumor is disclosed in prior art, mainly select the Chinese medicine with effects such as heat-clearing and toxic substances removing, blood circulation and promoting silt, resolving phlegm and softening hard masses, treating the poisonous disease with poisonous drugs to regulate the physiological function of the negative and positive of human body, gas, blood, internal organs and meridians, with improve body immune disease-resistance power, health invigorating, delay the state of an illness and suppress cancer development.Although some Chinese medicines obtain certain effect in clinical practice, overall treatment effect is bad, to the usefulness of medicine, influence factor and the mechanism of action not through scientific research and experiment.And many at present by the anticarcinogen that uses while causing cancer cell death, its serious toxic and side effects can cause Normocellular damage.Therefore, exploitation can capture tumor, again not injuring normal cell, and enhancing human body immunity function, promoting the medicine of rehabilitation, is current global key subjects.
Summary of the invention
For prior art above shortcomings, the object of this invention is to provide a kind of cost low, manufacturing process is simple and easy, and the suitability is wide, curative effect is reliable, normal cell is not almost had to the Chinese medicine of virose a kind of Therapeutic cancer.
For achieving the above object, the present invention is achieved through the following technical solutions: a kind of Chinese medicine of Therapeutic cancer, it is characterized in that by the medical material of following weight parts formulated: Radix Angelicae Sinensis 15-30 part, Herba Artemisiae Annuae 15-30 part, Radix Cirsii Japonici 15-30 part, Nidus Vespae 10-20 part, Radix Astragali 15-30 part, Semen Strychni (processed) 15-20 part, Resina Toxicodendri 10-15 part processed, Fructus Hippophae 15-25 part processed, Sal Nitri 20-30 part, Herba Agrimoniae 20-30 part, Herba Urticae Cannabinae 15-30 part, Fructus Aurantii 25-40 part.
Wherein preferred: Radix Angelicae Sinensis 28 parts, Herba Artemisiae Annuae 28 parts, Radix Cirsii Japonici 28 parts, 15 parts, Nidus Vespae, the Radix Astragali 25 parts, Semen Strychni (processed) 17 parts, Resina Toxicodendri processed 13 parts, Fructus Hippophae processed 20 parts, 25 parts, Sal Nitri, Herba Agrimoniae 28 parts, Herba Urticae Cannabinae 20 parts, Fructus Aurantii 30 parts.
Chinese medicine of the present invention can make powder, pill, suppository, capsule, injection etc. by the method for prior art.
The present invention makes according to following mechanism: according to tumor be " positive QI-insufficiency; heresy and contain; stasis forms " pathogeny, the present invention adopts natural drug Radix Angelicae Sinensis, Herba Artemisiae Annuae completely, Radix Cirsii Japonici is monarch drug, and the fragrant strongly fragrant row of Radix Angelicae Sinensis falls apart, to enrich blood promoting the circulation of blood, invigorating middle warmer has, and have benefit in row, blood must be supported, and stops up stagnant loose, blood is gentle to then skin infection rehabilitation, pain relief; Carbuncle diabrosis is then with nourishing blood and promoting granulation.Hectic fever due to YIN-deficiency consumptive fever specially separated by Herba Artemisiae Annuae, more pruritus caused by wind pathogen, only fidgets due to deficiency night sweat, and spleen is supported in appetizing, and improving eyesight exorcises evil spirits, and pain of feeling at ease, treats malignant boil, removing blood stasis with potent drugs granulation promoting, antibacterial, hemostasis, pain relieving, promotes that cellular immunization plays antitumaous effect; Pathogenic fire purging heat, not wasting QI-blood again, the medicine to help QI and blood of use.Monarch can can help and make by minister, without toward should not be also.Radix Cirsii Japonici cooling blood and relieving pain, treats carbuncle skin infection, and after curing the disease, body is empty.Monarch drug strengthens mutually, and the common removing mass of assaulting fortified position that plays is subsided a swelling, promoting blood circulation, removing blood stasis and relieving pain, effect of the strong body of nourishing blood and promoting granulation.Nidus Vespae wind dispelling insecticide, removing toxic substances counteracting toxic substances, blood stasis dispelling relieving convulsion, loose swollen blood stasis dispelling, heart tonifying diuresis, hemostasis analgesic therapy, Xing Yang reduces phlegm, antiallergic, antitumor; Control sore swollen toxin, acute mastitis tumor, scrofula swells and ache, stubborn dermatitis malignant boil, the stiff pain in joint, frightened convulsion migratory arthralgia, the sexual impotence enuresis, and with the anaphylactic reaction that the anti-Resina Toxicodendri of Herba Urticae Cannabinae may cause.The strong body of astragalus root nourishing, tonifying Qi and lifting yang, nourishing kidney spleen reinforcing, strengthening superficial resistance to stop perspiration, the evacuation of pus of holder skin ulcer, detumescence and promoting granulation, protects the liver diuresis; There is enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely; Control carbuncle skin ulcer to fester, do not close up for a long time and various cancers etc.Semen Strychni (processed) strengthens mass dissipating and swelling eliminating, and removing obstruction in the collateral to relieve pain, expelling the stasis for the new, activated bone marrow hematopoietic function, antiphlogistic antibacterial, is applicable to various cancerous protuberance.Resina Toxicodendri processed strengthens removing blood stasis, and hard masses softening and resolving, stimulates the menstrual flow, removing food stagnancy.Fructus Hippophae processed strengthens promoting blood circulation to remove blood stasis, and reduce phlegm the chest stuffiness relieving, relieving dyspepsia, promoting the production of body fluid to quench thirst, clearing away heat to stop diarrhea, strengthens macrophage function, has resisting fatigue and enhancing body vigor and the special pharmacological performance such as anticancer, and promote wound healing, therefore both can supplement the nutrients, the resistance against diseases of body can be improved again.Sal Nitri is strengthened broken tumor and to be disappeared heavily fortified point, and the skin ulcer that disappears eliminating impediment, pain relieving profit is drenched.This Six-element medicine is minister, and coordinate monarch drug mutually to work in coordination with, strengthen curative effect, treating the poisonous disease with poisonous drugs, toxin expelling eliminating stagnation, strengthening the body resistance, strong body is eliminating evil, pushes away Chen Zhixin, refreshment and brain nourishing.Herba Agrimoniae is adjuvant drug, assists monarch drug to relieve internal heat anticancer, cooling blood for hemostasis, detumescent of healing the wounds, heat-clearing and toxic substances removing, QI invigorating Xing Yang.Herba Urticae Cannabinae is dispeled the wind, and invigorates blood circulation, pain relieving, antiallergic, anticancer swollen pain; The loose painful abdominal mass of the broken knot of Fructus Aurantii, the chest stuffiness relieving of regulating the flow of vital energy, stomach invigorating removing food stagnancy, two medicines are for making to work in coordination with and strengthening effect that monarch drug plays anticancer righting altogether.The mutual Synergistic of said medicine, strengthening vital QI to eliminate pathogenic factors, lifts sun and presses down cloudy, hard masses softening and resolving, Yin Yang balancing, inducing diuresis to remove edema, heat clearing away can let out poison, stasis-dispelling and pain-killing, and temperature compensation can carry gas again, spleen invigorating is dredged stagnant, adjust the five internal organs, fill blood, improve body's immunity, enhancing body anti-cancer ability, be i.e. " righting, act sun "; Improve the environment of body simultaneously, excite reverse or the extinction of cancerous cell, be i.e. " eliminating evil, press down cloudy ", to reach strengthening the body resistance, cancer disappears effect of body Thailand, and this is that " in healthy energy deposits, heresy can not be done." pharmacological effect of each component of the present invention is as follows:
1, Radix Angelicae Sinensis (Angelicasinensis), nature and flavor are sweet, pungent, warm, GUIXIN, liver, spleen channel.Function cures mainly: nourishing blood and promoting granulation, promoting blood circulation and stopping pain, skin moistening of enriching blood, and broken heap soil or fertilizer over and around the roots is dredged stagnant, loosening bowel to relieve constipation.Control all cards of blood deficiency, flaccidity syndrome and arthralgia syndrome, menoxenia, amenorrhea dysmenorrhea, lump in the abdomen knot is poly-, bleeding not during menses, asthenia cold abdominalgia, weight, ulcer sores, traumatic injury etc. after dryness of the intestine constipation, bloody dysentery.
2, Herba Artemisiae Annuae (Artemisiacarvifolia) is a kind of plant of Compositae artemisia, nature and flavor bitter, acrid, cold, returns liver, gallbladder, three burnt, kidney channels.Function cures mainly: clear deficiency-heat thoroughly, removing heat from blood removes and steams, expelling summer-heat, preventing the attack (or recurrence) of malaria.Control pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat.Studies have reported that, arteannuin has immunoloregulation function, and intravenous injection arteannuin 50-100mg/kg can significantly improve Turnover of Mouse Peritoneal Macrophages phagocytic rate and phagocytic index.Arteannuin also can improve lymhocyte transformation rate, promotes immunization of cell.Artesunate can promote Ts cell proliferation, suppresses TE cell to produce, stops the release of interleukin and various inflammatory mediator, thus play immunoregulation effect, play anticancer usefulness.
3, Radix Cirsii Japonici (CirsiumjaponicumFisch.exDC), Compositae, artichoke plant, the herb of Ji or root, nature and flavor are sweet, bitter, cool; GUIXIN, Liver Channel.Function cures mainly: cooling blood for hemostasis, blood stasis dispelling eliminating carbuncle, invigorating QI and tranquilization; Control epistaxis, haematemesis, hematuria, have blood in stool, bleeding not during menses, traumatic hemorrhage, carbuncle sore tumefacting virus, after being ill body are empty.
4, Nidus Vespae is Vespidae insecticide fruit hornet Polistesolivaceous(DeGeer), the nest of Japanese long foot wasp PolistesjaponicusSaussure or different abdomen wasp ParapolybiavariaFabricius.Nature and flavor are bitter, salty or sweet, flat.Return stomach warp.Enter bright, the liver of sun, lung meridian.Effect: wind dispelling insecticide, removing toxic substances counteracting toxic substances, blood stasis dispelling relieving convulsion, loose swollen blood stasis dispelling, heart tonifying diuresis, hemostasis analgesic therapy, Xing Yang reduces phlegm, antiallergic, antitumor; Control sore swollen toxin, acute mastitis tumor, scrofula swells and ache, stubborn dermatitis malignant boil, the stiff pain in joint, frightened convulsion migratory arthralgia, the sexual impotence enuresis and anaphylactic disease etc.
5, the Radix Astragali (Astragalusmembranaceus (Fisch.) Bunge.), pulse family Astragalus.Nature and flavor are sweet, tepor.Return lung, spleen, liver, kidney channel.Function cures mainly: nourishing and body-strengthening, tonifying Qi and lifting yang, nourishing kidney spleen reinforcing, strengthening superficial resistance to stop perspiration, and the evacuation of pus of holder skin ulcer, detumescence and promoting granulation, protects the liver diuresis.The history of medicinal existing more than 2000 year so far of the Radix Astragali, it has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely; Control carbuncle skin ulcer to fester, do not close up for a long time and various cancers etc.
6, Semen Strychni (Strychnosnux-vomicaLinn), Loganiaceae Strychnos.Nature and flavor are bitter, cold, and poison, returns liver, spleen channel greatly.Function cures mainly: removing obstruction in the collateral to relieve pain, dispersing swelling and dissipating binds, expelling the stasis for the new, antiphlogistic antibacterial, refreshment, and stomach invigorating is ventilated, toxic removing removing heat from blood; Control mammary gland tumor, carbuncle pyogenic infections from tumour or sore and swelling and pain due to blood stasis, throat arthralgia pain, mass in the abdomen cancerous protuberance, anemofrigid-damp arthralgia, neural paralysis, myasthenia gravis, poliomyelitis, inappetence, abdominal distention constipation etc.
7, Resina Toxicodendri is Anacardiaceae plant Toxicodendron verniciflnum (Stokes) F. A. Barkley (Rhus verniciflua Stokes) (Toxicodendronvernicifluum(Stokes) F.A.Barkl.) resin through processing after dry product.Nature and flavor are pungent, warm, mild toxicity, return liver, spleen channel.Function cures mainly: removing blood stasis with potent drugs blood, and by stagnant long-pending, stimulate the menstrual flow parasite killing.Control women's amenorrhea, blood stasis lump in the abdomen, abdominal pain due to worm stagnation etc.
8, Fructus Hippophae, is the fruit of Elaeangnaceae hippophae plant Fructus Hippophae (HippophaerhamnoidesL.), has another name called fructus hippophae, sour bur.Property is sour, puckery, warm.Function cures mainly: promoting blood circulation to remove blood stasis, and reduce phlegm the chest stuffiness relieving, relieving dyspepsia, promoting the production of body fluid to quench thirst, clearing away heat to stop diarrhea.Control and fall damage congestive edema, blood stasis amenorrhea, lung abscess, cough with copious phlegm, stomachache, dyspepsia, enteritis and dysentery, high thermal burn is cloudy.In Fructus Hippophae, flavone can improve SC level, strengthens the function of macrophage, therefore both can supplement the nutrients, can improve again the resistance against diseases of body.Containing 206 kinds of active substances useful to human body in Oleum Hippophae; wherein there are 46 kinds of bioactive substances; containing a large amount of vitamin Es, vitamin A, pyrite etc.; there is resisting fatigue and enhancing body vigor and the special pharmacological performance such as anticancer; protect and accelerate to repair gastric mucosa, increasing intestinal bifidobacteria, fall and subtract plasma cholesterol; anti-curing hyperlipemia and atherosclerosis, and have the effect promoting wound healing.
9, Sal Nitri, also known as flame nitre, niter etc., be a kind of natural minerals, main component is potassium nitrate, and nature and flavor are bitter, cold.Function cures mainly: removing mass is loose hard, and the skin ulcer that disappears is except painful abdominal mass, and blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema, fossil profit is drenched, pain relieving.Control a severe pain, chest pain, waist is suffered from abdominal pain, and be envious and swell and ache, eyes is hidden from view, sore throat, dysentery, pouring disease, back of the body cellulitis urticaria etc.
10, Herba Agrimoniae is the aerial parts of rosaceous plant Agrimony (AgrimoniapilosaLedeb.), and nature and flavor are bitter, cool, return stomach, liver, spleen, lung, large intestine channel.Function cures mainly: anticancer, the cooling blood for hemostasis of relieving internal heat, detumescent of healing the wounds, preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances.Control the various heat in blood such as gastric cancer, the esophageal carcinoma, hepatocarcinoma, palace body adenocarcinoma, breast carcinoma, leukemia, hemoptysis, haematemesis, epistaxis hemorrhage, carbuncle, malaria, de-power impairment caused by overstrain etc.
11, Herba Urticae Cannabinae (Nettle) is the root of Urticaceae Urtica plant.Nature and flavor are bitter, pungent, temperature; Slightly poisonous.Function cures mainly: dispel the wind, and invigorates blood circulation, pain relieving, antiallergic.Swollen pain for cancer, rheumatic ostalgia, urticaria, eczema, snakebite, hypertension etc.
12, Fructus Aurantii, this product is the dry immature fruit of rutaceae Citrus aurantium Linn. (CitrusaurantiumL.) and variety thereof.Nature and flavor are bitter, pungent, sour, warm, return spleen, stomach warp.Function cures mainly: dispelling the stagnated QI reduces phlegm, the loose painful abdominal mass of broken knot, and the chest stuffiness relieving of regulating the flow of vital energy, removing food stagnancy stomach invigorating, dredges the stagnant heap soil or fertilizer over and around the roots that disappears.Control the breast side of body stagnation of QI, coerce swollen pain, accumulation of food in the stomach and intes tine due to indigestion, stop in phlegm retention, the feeling of stuffiness in chest, eructation, vomiting, heavy after dysentery, gastroptosis, proctoptosis, uterine prolapse etc.
For studying the mechanism of action, cytotoxicity and the immunologic function of Chinese medicine of the present invention " anticancer righting is fallen apart ", inventor poplar ten thousand spring from 2008 so far, found University Medical College department of physiology with the celebrating northern part of the country, Taegu of Korea S to cooperate, completed to the usefulness of " anticancer righting is fallen apart " with at the Effect study of animal model to tumor cell.Method various dose " anticancer righting is fallen apart " the process cancerous cell adopted in this achievement in research and mouse macrophage, the activity of cell is detected by MTT analytical method, and carry out morphological observation, testing cancerous cell used has lung carcinoma cell, prostate gland cancer cell, hepatoma carcinoma cell, breast cancer cell, macrophage etc.With the cytokine gene expression of real-time polymerase chain reaction fluorescence quantitative PCR detection macrophage, detect the phagocytic function of macrophage with phagocytosis test.Through overtesting, confirm that " anticancer righting is fallen apart " safety range is large, only than under the concentration using anticancer dosage to exceed nearly a hundred times, just toxic to cell.Its mechanism of action is that activating macrophage phagocytic function engulfs cancerous cell, and the inducing tumor necrosis factor-a(TNF-a), the generation of the cytokine such as interleukin (IL) 1,6,10 and monocyte chemoattractant protein-1 (MCP-1), thus Tumor suppression growth or promotion cancer cell death, play anticancer centralizing function.
Compared with prior art, the beneficial effect that the present invention has has:
1, Chinese medicine of the present invention does not almost have toxicity to normal cell, only than under the concentration using anticancer dosage to exceed nearly a hundred times, just toxic to normal cell.Fill up existing reliable anticancer effect, again without the cancer therapy drug blank of normal cell damage.
2, the technology of the present invention is ripe, curative effect is reliable, the kinds cancers such as gastric cancer, hepatocarcinoma, esophageal carcinoma, lymphatic cancer, cerebroma, pulmonary carcinoma, nasopharyngeal carcinoma, uterus carcinoma, breast carcinoma, renal carcinoma, bladder cancer, carcinoma of prostate can be treated, and various early, middle and late phase malignant tumor can be adapted to; Through the clinical trial of part malignant tumor patient, curative effect is reliable.
3, to have medicine source wide, cheap and easy to get, it is simple to make in the present invention, and the suitability is wide, the advantages such as medical expense is low.If general cancer patient adopts radiotherapy or chemotherapy, the average annual expense of people is more than 100,000 yuan, and uses treatment by Chinese herbs of the present invention, and the average annual expense of people need, 2-3 ten thousand yuan, be only 1/5th of conventional therapy.
Usage of the present invention and consumption: depending on the state of an illness of different patient, each 1-6 gram, every day 3 times, warm water is swallowed, and within 30 days, is 1 course for the treatment of, generally serve on 3 to 6 courses for the treatment of.Some meetings are more longer, the course for the treatment of interval 3-5 days; Whether after symptom, sign disappear completely, every half a year takes 1 course for the treatment of, after 3,4 courses for the treatment of, change into and take 1-2 the course for the treatment of every year and carry out after treatment, take medicine, depending on the concrete state of an illness later.
Below in conjunction with clinical laboratory data, therapeutic effect of the present invention is described:
1, physical data
Inventor collects out-patient's (man 68 example that 100 routine hospitals are diagnosed as cancer altogether between year January April to 2011 nineteen ninety, female 32 example, age 6-78 year, 40-49 year accounts for 18%, 50-59 year accounts for 20%, 60-69 year accounts for 36%, 70 years old and account for 12% above, be less than 40 years old and account for 14%), wherein gastric cancer accounts for 28%, pulmonary carcinoma accounts for 12%, cerebroma accounts for 10%, hepatocarcinoma and esophageal carcinoma account for 16%, rectal cancer and pancreas cancer account for 10%, uterus carcinoma accounts for 4%, duodenal carcinoma, colon cancer, Gallbladder Adenocarcinoma, breast carcinoma, carcinoma of parotid gland, nasopharyngeal carcinoma, renal carcinoma, bladder cancer, malignant lymphoma, acute lymphoblastic leukemia accounts for 20%.Observe Chinese medicine of the present invention over the course for the treatment of to gastric cancer, hepatocarcinoma, esophageal carcinoma, lymphatic cancer, cerebroma, curative effect is outstanding especially, takes second place to pulmonary carcinoma, nasopharyngeal carcinoma, uterus carcinoma, breast carcinoma, renal carcinoma, bladder cancer curative effect, also has curative effect in various degree to other cancers.
2, test method
2.1 Therapeutic Method
Matched group oral placebo sticks with paste rice Fagopyrum esculentum Moench powder, and each 3 grams, every day 3 times, warm water is swallowed, 90 days courses for the treatment of.
The Chinese medicine that the oral specific embodiment of the invention embodiment for the treatment of group 1 is obtained, each 3 grams, every day 3 times, warm water is swallowed, 90 days courses for the treatment of.
2.2 observation item
Treatment Patients Before And After body weight, blood pressure, routine blood test, anemia, pain, become thin, weak, edema, inappetence, heating, vomit, the change of the symptom such as to have blood in stool.Lab testing cancerous tissue size variation and deterioration.Record drug withdrawal patient's Survival after 2 years.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms takes a turn for the better gradually and even disappears, test chamber checks that cancerous tissue disappears or transfers to optimum, survives and gradually recovers one's health and have no recurrence for 2 years.
Take a turn for the better: clinical symptom relief, lab testing cancerous tissue stops diffusion or growth, survives more than 2 years.
Invalid: clinical symptoms is without being clearly better or continuing to increase the weight of, and lab testing cancerous tissue continues diffusion or growth, dead in two years.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
| Group | Case (example) | Recovery from illness (example) | Take a turn for the better (example) | Invalid (example) | Total effective rate (%) |
| Treatment group | 70 | 48(68%) | 21 | 1 | 98 |
| Matched group | 30 | 0(0%) | 1 | 29 | 3 |
Visible, the Chinese medicine that the present invention obtains can safe and effective treatment kinds cancer.After general patient takes medicine one week, mental status generally takes on a new look, and pain, edema alleviate, and appetite is progressively recovered, and temperature recovery is normal; After continuing to take medicine two weeks, mass reduction, disease is day by day alleviated, and blood pressure, hemogram improve, and body weight is gone up, and body constitution strengthens day by day; After three weeks, symptom disappears substantially; After six weeks, energy daily routines, manage household affairs; Adhere to taking 3-6 the course for the treatment of, a course for the treatment of is 30 days, and generally sb.'s illness took a favorable turn, part recovery from illness.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, but is not limited to embodiment.
Embodiment 1
A Chinese medicine for Therapeutic cancer, is characterized in that by the medical material of following weight parts formulated: Radix Angelicae Sinensis 28 parts, Herba Artemisiae Annuae 28 parts, Radix Cirsii Japonici 28 parts, 15 parts, Nidus Vespae, the Radix Astragali 25 parts, Semen Strychni (processed) 17 parts, Resina Toxicodendri processed 13 parts, Fructus Hippophae processed 20 parts, 25 parts, Sal Nitri, Herba Agrimoniae 28 parts, Herba Urticae Cannabinae 20 parts, Fructus Aurantii 30 parts.
The preparation method of this Chinese medicine above-mentioned medical material is removed impurity, dries, after pretreatment, weighs, mixes, pulverizes, by 100 mesh sieve, make after packaging by described weight portion.Prescription meets the sanitary standard that the Pharmacopoeia of the People's Republic of China (nineteen ninety-five version one) annex powder general rule requires and Ministry of Public Health specifies.
Wherein the manufacture method of Semen Strychni (processed) is the method adopting the Pharmacopoeia of the People's Republic of China (version in 1985) to record, and namely gets sand and puts in pot, after making popular with high heat, add clean Semen Strychni, constantly stir, scald to heaving and showing sepia or dark-brown, take out, sieve removes sand, cools for subsequent use.
Wherein the manufacture method of Resina Toxicodendri processed adopts the method recorded in " Chinese herbal medicine Processing methods handbook " (Shandong People's Press .1971.12. first edition), namely Resina Toxicodendri knock fritter, puts in iron pan and be fired in bulk shiny black bulk, takes out, cool for subsequent use.
Wherein the manufacture method of Fructus Hippophae processed is: get sand and enter after iron pan intense fire is made popular to add clean Fructus Hippophae, constantly stir, and scald and show brown or dark-brown taking-up to epidermis, sieve removes sand, for subsequent use by drying after Fructus Hippophae rapid water rinsing.
The Chinese medicine scope of application of the present invention: various early, middle and late phase malignant tumor, precancerous lesion, immunization therapy, operation, radiotherapy, chemotherapeutic period and anaphase thereof.As by Chinese medicine of the present invention and some chemical drugs use in conjunction, synergism is played in treatment, and the toxic and side effects of chemotherapeutics can be alleviated.Chinese medicine of the present invention can improve the hemogram after schistosomicide hepatic injury and chemotherapy, without cytotoxicity such as alopecia, oral ulcer, bone marrow depression.
Embodiment 2
A Chinese medicine for Therapeutic cancer, is characterized in that by the medical material of following weight parts formulated: Radix Angelicae Sinensis 15 parts, Herba Artemisiae Annuae 15 parts, Radix Cirsii Japonici 15 parts, 10 parts, Nidus Vespae, the Radix Astragali 15 parts, Semen Strychni (processed) 15 parts, Resina Toxicodendri processed 10 parts, Fructus Hippophae processed 15 parts, 20 parts, Sal Nitri, Herba Agrimoniae 20 parts, Herba Urticae Cannabinae 15 parts, Fructus Aurantii 40 parts.All the other are with embodiment 1.
Embodiment 3
A Chinese medicine for Therapeutic cancer, is characterized in that by the medical material of following weight parts formulated: Radix Angelicae Sinensis 30 parts, Herba Artemisiae Annuae 30 parts, Radix Cirsii Japonici 30 parts, 20 parts, Nidus Vespae, the Radix Astragali 30 parts, Semen Strychni (processed) 20 parts, Resina Toxicodendri processed 15 parts, Fructus Hippophae processed 25 parts, 30 parts, Sal Nitri, Herba Agrimoniae 30 parts, Herba Urticae Cannabinae 30 parts, Fructus Aurantii 40 parts.
The typical case enumerating treatment below falls ill:
Case 1: Li Xiangyu, female, 50 years old, lie up in Nujiang Autonomous Prefecture of Yunnan Province the People's Hospital.Cause hematemesis repeatedly, melena 5 days, in Zhu No.1 Hospital Attached to Kunming Medical College in April 11 nineteen ninety.Previously there are " ulcer of upper digestive tract " history of repeated attack 8 years; Gastrorrhagia 5 times, is in hospital 3 times.Have a medical check-up: ordinary circumstance is poor, dyscrasia, critical sickly complexion, body weight 34 kilograms.Cardiopulmonary are without exception; Epigastrium tenderness is obvious, and liver spleen is without enlargement, and sign of ascites is negative.After being admitted to hospital, hemoglobin is that Progressive symmetric erythrokeratodermia declines, and can reach 3.5g/dl time minimum.Gastroscope (#900590) is diagnosed: 1, gastric cancer; 2, duodenal bulbar ulcer (cicatricial phase); Sick inspection (#90-2600) is diagnosed as poorly differentiated adenocarcinoma, signet-ring cell carcinoma.Row " stomach radical correction " a course for the treatment of of systemic chemotherapy, improvement is left hospital.Can't stand chemotherapy because of resistance to after leaving hospital, impose Chinese medicine of the present invention " anticancer righting is fallen apart " oral, each 2 grams, every day 3 times, change into after half a year and monthly take 2 weeks.Physical rehabilitation after 1 year, can manage household affairs, after change each 1 gram into, every day 2 times, take medicine every half a year 1 week, check gastroscope and sick inspection to nineteen ninety-five to former operation hospitals, result is cured and drug withdrawal completely.So far follow up a case by regular visits to patient to be still living and in good health, and also manage household affairs.
Case 2: Yang Yanzhen, female, 41 years old, Xin Tun town, Dali Prefecture, Yunnan Province Heqing County Red Star village peasant.To occur together hot first quarter moon because continuing right hypochondrial region, treating in Lai in May 22 Heqing County in 1997 the People's Hospital.Because of busy farming season tired Hou Ganyoulei district persistence distending pain, twinge before patient's first quarter moon, aggravate in Progressive symmetric erythrokeratodermia, pain to homonymy shoulder, arm radiation, to making limb activity limited, upright or flat sleeping time pain more so, general antipyretic analgesic can not be alleviated.Occur together heat, poor appetite, weak, gradually becomes thin, facial edema etc.Local diagnosis " liver abscess ", infusion heavy dose " ampicillin, micronomicin, metronidazole " and to the ill more than 10 days of Supporting Therapy are invalid.Previously have " schistosomicide " history, ediblely to salt down for a long time, cured saline taste product.Have a medical check-up: T38.3 DEG C, P96 beat/min, R24 beat/min, BP110/70mmHg.Shallow complexion, facial edema, anemia looks, chronic pain sickly complexion, body weight 43 kilograms, right front flexing position, walks with difficulty.Light red tongue is purple, white and thin fur, wiry and frequent pulse.Cardiopulmonary are normal.Right hepatic region tenderness, kowtow pain, the liver upper bound rises to right midclavicular line the 4th intercostal space, the flat arcus costarum lower edge of lower bound.Blood RBC3.6 × 10
12/ L, HGB95g/L, WBC10.3 × 10
9/ L; Liver function is normal, and HBsAg is negative, AFP strong positive; Two is just normal; B ultrasonic (#19524) is shown in that liver form is regular, density unevenness, and have an appointment the slightly low echo area of 33 × 25mm in right hepatic region, internal echo is uneven, prompting: 1, schistosomicide hepatic injury; 2, right lobe of liver solid enclosed mass character is undetermined; Chest just, position, side X-ray film (#30134) shows: right diaphragm raises, and considers canceration under diaphragm.First visit: primary hepatocarcinoma (inflammatory type), impose each 5 grams of Chinese medicine of the present invention " anticancer righting is fallen apart ", every day 3 times, swallow with Radix Artemisia ordosicae soup, be aided with to the ill Supporting Therapy 1 week, symptom slightly alleviates, May 28 to Lijiang City examination in hospital, liver function was normal, and HBsAg is negative, B ultrasonic (#1982) is shown in that in the right back leaf of liver, part is visited and size about 20 × 20mm slightly low echo area, owe clear with demarcating around, liver size and form is normal, and essence echo increases thick in latticed change, skewness, prompting: 1, the right back leaf of liver slightly low echo area (character is undetermined); 2, schistosomicide hepatic injury ultrasonogram; 3, spleen slightly enlargement.Treatment 1 week before continuous, symptom and spirit are improved further, and appetite increases.Clarified a diagnosis June 3 to Dali prefecture the People's Hospital, CT scan (#10247) is shown: hepatomegaly, the low-density stoves such as the visible about 4 × 4cm size of right lobe of liver epimere, heterogeneity strengthening is showed after CE, through delayed sweep, focal zone still shows a cryptomere low-density stove, and in capsule, CT value is 21Hu, diagnostic comments " hepatocarcinoma, suggestion is done AFP association and examined "; AFP was put and was exempted from testing result higher than normal value June 6.Before continuous, treatment is to further consultation on June 13, and symptom disappears substantially, and diet, close to normal, is still felt weak.Look into: the weak positive of AFP, without kowtowing pain, is surveyed in hepatic region.Before continuous, treatment is to further consultation on August 15, and the further rehabilitation of health, can be engaged in general housework.Look into: liver upper right circle recovers normal; Blood RBC4.2 × 10
12/ L, HGB116g/L, WBC4.6 × 10
9/ L, PLT259 × 10
9/ L; Liver function is normal, AFP negative.B ultrasonic shows: the slightly low echo area of the former 33 × 25mm in right hepatic region disappears.Continuous " anticancer righting is fallen apart " decrement, to each 3 grams, every day 3 times, is checked to Dali prefecture the People's Hospital to JIUYUE, CT(#10247 on the 6th) to show: the low-density such as liver parenchyma density is normal, shows homogeneous strengthening, compare with CT on June 3 after CE, lobus dexter disappear.Continuous with " anticancer righting is fallen apart " drug withdrawal after 1 week.Disease is fully recovered, follows up a case by regular visits to so far, alive without uncomfortable, participates in field and housework always.
Case 3: Yang Xiuqian, female, 62 years old, the retirement of Di-qing County, Yunnan Uighur women personnel bureau.Because making a definite diagnosis " liver metastases cancer " April, treat in Lai in October 13 Heqing County in 1997 the People's Hospital.Patient from 1992 in Dali prefecture the People's Hospital row " duodenum sarcoma " excision; June in the same year " find epigastrium enclosed mass January remaining " lives former operation hospitals again, through CT(#10277) and put and exempt from AFP and measure and make a definite diagnosis.Due to " lump is huge, and liver left and right leaf all involves, and loses opportunity of operation ", leave hospital through systemic chemotherapy.Postabdomen enclosed mass of leaving hospital continue increase, in JIUYUE be again in hospital row secondary chemotherapy, period color ultrasound show: liver enlargement, the multiple Space Occupying Solid Lesion of liver, wherein maximum one is 13 × 9.7cm.After end of chemotherapy is left hospital, giddy, tinnitus, weak, bitter taste, upper abdomen Men Zhangjilei district distending pain, sled pain increase the weight of day by day, so that limitation of activity, and anorexia.Ordinary circumstance is poor, and shape is thin sallow, exhaustion, dyscrasia, body weight 35 kilograms.Crimson tongue is purple, and tongue is stripped off, stringy and thready pulse, and cardiopulmonary are normal.Epigastrium is swelled, and can touch about 25 × 18 × 6cm essence enclosed mass.Blood RBC3.33 × 10
12/ L, HGB97g/L, PLT99 × 10
9/ L, WBC3.3 × 10
9/ L, GRA48%; Two is just conventional normal; Liver function is normal, and HbsAg is negative.B ultrasonic (#349) shows: liver parenchyma Echo heterogenicity matter, has multiple low echo area differed in size in it, and maximum twoth district are respectively 173 × 98mm, 88 × 68mm.Hospital informs that family members patient is unlikely to survive several months, for it prepares funeral affairs.Impose Chinese medicine of the present invention " anticancer righting is fallen apart " oral, each 3 grams, every day 3 times, patients symptomatic fades away, and diet recovers normal, can manage household affairs.Over the course for the treatment of, repeatedly do B ultrasonic and observe, liver enclosed mass Progressive symmetric erythrokeratodermia reduces.Further consultation again on November 26 in 1997, patient does not tell discomfort.Look into: epigastrium enclosed mass is reduced to 12 × 8.5 × 2.5cm, B ultrasonic (#719) shows: in liver, maximum two low echo areas are respectively 104 × 95mm, 87 × 56mm.Treat more than half a year before continuous, after 6 years, patient is dead.
Case 4: Zhao Kechun, man, 67 years old, Heqing Party school of county Party committee left one's post.Find cervical region Silent Neuritis lump more than 7 years, successively carry out check pathological section to DaLi Medicine Academy (sick inspection #960334) and on January 15th, 1998 to the Kun Yifu First Academy (sick inspection #97-9) on April 11st, 1996, be diagnosed as " Non-Hodgkin ' sMalignant Lymphomas ".Carry out local enlarged lymph node excision for several times therebetween, impose chemotherapy simultaneously.Each chemotherapy tumor is all recurred again after of short duration control and spreads also Progressive symmetric erythrokeratodermia to be increased the weight of, and treats in Lai in August 10 Heqing County in 1998 the People's Hospital.Patient's ordinary circumstance is poor, right neck can touch the lymph node that several Semen Castaneae is differed in size to Semen arachidis hypogaeae sample, matter is hard, rough, edge adhesion, restriction of neck motion, imposes Chinese medicine of the present invention " anticancer righting is fallen apart " oral, each 1.5 grams, 3 treatments every day, a further consultation in month, diet and mental status take a turn for the better, lump deliquescing and without continuation increase increase, cervical region activity makes moderate progress, continuous with " anticancer righting is fallen apart " 3.0 grams, every day 3 times, Radix Artemisia ordosicae soup is swallowed, continuous treatment looks into mass reduction to Semen Glycines size after three months, matter is soft, and cervical region activity freely.Disease has been fully recovered and has not been recurred, and is still living and in good health so far.
Claims (2)
1. a Chinese medicine for Therapeutic cancer, is characterized in that by the medical material of following weight parts formulated: Radix Angelicae Sinensis 15-30 part, Herba Artemisiae Annuae 15-30 part, Radix Cirsii Japonici 15-30 part, Nidus Vespae 10-20 part, Radix Astragali 15-30 part, Semen Strychni (processed) 15-20 part, Resina Toxicodendri 10-15 part processed, Fructus Hippophae 15-25 part processed, Sal Nitri 20-30 part, Herba Agrimoniae 20-30 part, Herba Urticae Cannabinae 15-30 part, Fructus Aurantii 25-40 part.
2. the Chinese medicine of a kind of Therapeutic cancer according to claim 1: it is characterized in that by the medical material of following weight parts formulated: Radix Angelicae Sinensis 28 parts, Herba Artemisiae Annuae 28 parts, Radix Cirsii Japonici 28 parts, 15 parts, Nidus Vespae, the Radix Astragali 25 parts, Semen Strychni (processed) 17 parts, Resina Toxicodendri processed 13 parts, Fructus Hippophae processed 20 parts, 25 parts, Sal Nitri, Herba Agrimoniae 28 parts, Herba Urticae Cannabinae 20 parts, Fructus Aurantii 30 parts.
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| CN1073866A (en) * | 1992-08-09 | 1993-07-07 | 付耀华 | Oral liquid for curing cancer and compound method thereof |
| CN101543616A (en) * | 2009-04-21 | 2009-09-30 | 闫树清 | Traditional Chinese medicine composition for preventing and treating tumor and its preparation method |
| CN102274361A (en) * | 2011-07-29 | 2011-12-14 | 李丰曹 | Anticancer medicinal composition and preparation method of decoction thereof |
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| CN1073866A (en) * | 1992-08-09 | 1993-07-07 | 付耀华 | Oral liquid for curing cancer and compound method thereof |
| CN101543616A (en) * | 2009-04-21 | 2009-09-30 | 闫树清 | Traditional Chinese medicine composition for preventing and treating tumor and its preparation method |
| CN102274361A (en) * | 2011-07-29 | 2011-12-14 | 李丰曹 | Anticancer medicinal composition and preparation method of decoction thereof |
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