CN104027447A - Traditional Chinese medicine for treating cancer - Google Patents

Traditional Chinese medicine for treating cancer Download PDF

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CN104027447A
CN104027447A CN201410319488.4A CN201410319488A CN104027447A CN 104027447 A CN104027447 A CN 104027447A CN 201410319488 A CN201410319488 A CN 201410319488A CN 104027447 A CN104027447 A CN 104027447A
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CN104027447B (en
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杨万泉
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Abstract

The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine for treating cancer. The traditional Chinese medicine is prepared from, by weight, 15-30 parts of angelica sinensis, 15-30 parts of sweet wormwood herbs, 15-30 parts of setose thistle, 10-20 parts of honeycombs, 15-30 parts of astragalus, 15-20 parts of processed semen strychni, 10-15 parts of processed dried lacquer, 15-25 parts of processed sea buckthorn fruit, 20-30 parts of saltpeter, 20-30 parts of agrimonia pilosa, 15-30 parts of urtica and 25-40 parts of fructus aurantii. The traditional Chinese medicine is hardly toxic to normal cells and is only toxic to the normal cells on the condition with the concentration approximately higher than that of the amount of adopted anticancer agents by a hundredfold. The traditional Chinese medicine fills the blank of anticancer drugs which have reliable anticancer effect without harming the normal cells. The traditional Chinese medicine has the advantages of wide in applicability and low in treatment cost; medicine sources are wide, low in price, and easy to obtain and manufacture.

Description

A kind of Chinese medicine for the treatment of cancer
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of cancer.
Background technology
Tumor is a great problem of world today's medical science tackling key problem, and the mankind's Jiankang and life security in serious threat.Death toll is nearly ten million cancer year in the world, and China approximately has people up to a million to die from malignant tumor every year.Unclear yet at present to the etiology and pathogenesis of tumor, still, normal histiocyte is under certain unfavorable factor or certain environmental conditions, and producer sudden change has occurred that paraplasm is tumor this point and builds consensus.
At present, modern medicine treatment malignant tumor method is more, but there is no specific treatment.Gene therapy can be the mankind and captures malignant tumor and open up new channel, but cost is high, expense is expensive, common people can bear absolutely not, there is major defect as the method such as radiotherapy, chemotherapy in other, lacks specificity, mostly when tumor cell is killed and wounded, normal histiocyte is is also killed and wounded, to making many patients shorten life cycle because serious toxicity reacts.
Traditional medicine think tumor be " positive QI-insufficiency, heresy and contain, stasis forms.", Chinese traditional treatment cancer is divided into righting and eliminating evil two aspects.Righting by regulating autoimmune function, reaches anticancer object; The eliminating evil focus that directly tackles, suppresses tumor growth.The Chinese medicine of some treatment malignant tumor is disclosed in prior art, be mainly select there is heat-clearing and toxic substances removing, the Chinese medicine of the effect such as blood circulation and promoting silt, resolving phlegm and softening hard masses, treating the poisonous disease with poisonous drugs regulates the physiological function of negative and positive, gas, blood, internal organs and the meridians of human body, with improve body immune disease-resistance power, health invigorating, delay the state of an illness and suppress cancer development.Although some Chinese medicines are obtained certain effect in clinical practice, overall therapeutic effect is bad, and usefulness, influence factor and the mechanism of action to medicine are not passed through scientific research and experiment.And many anticarcinogens that used are at present in causing cancer cell death, its serious toxic and side effects can cause Normocellular damage.Therefore, exploitation can be captured tumor, and injuring normal cell not again, and enhancing human body immunity function promote the medicine of rehabilitation, are current global key subjects.
Summary of the invention
For prior art above shortcomings, the object of this invention is to provide a kind of cost low, manufacturing process is simple and easy, and the suitability is wide, curative effect is reliable, and normal cell is not almost had to virose a kind of Chinese medicine for the treatment of cancer.
For achieving the above object, the present invention is achieved through the following technical solutions: a kind of Chinese medicine for the treatment of cancer, is characterized in that by the medical material of following weight parts formulated: Radix Angelicae Sinensis 15-30 part, Herba Artemisiae Annuae 15-30 part, Radix Cirsii Japonici 15-30 part, Nidus Vespae 10-20 part, Radix Astragali 15-30 part, Semen Strychni (processed) 15-20 part, Resina Toxicodendri 10-15 part processed, Fructus Hippophae 15-25 part processed, Sal Nitri 20-30 part, Herba Agrimoniae 20-30 part, Herba Urticae Cannabinae 15-30 part, Fructus Aurantii 25-40 part.
Wherein preferred: 28 parts of Radix Angelicae Sinensis, 28 parts of Herba Artemisiae Annuaes, 28 parts of Radix Cirsii Japonicis, 15 parts, Nidus Vespae, 25 parts of the Radixs Astragali, 17 parts of Semen Strychni (processed)s, 13 parts of Resina Toxicodendri processed, 20 parts of Fructus Hippophae processed, 25 parts, Sal Nitri, 28 parts of Herba Agrimoniaes, 20 parts of Herba Urticae Cannabinaes, 30 parts of Fructus Aurantiis.
Chinese medicine of the present invention can be made powder, pill, suppository, capsule, injection etc. by the method for prior art.
The present invention makes according to following mechanism: according to tumor be " positive QI-insufficiency; heresy and contain; stasis forms " pathogeny, it is monarch drug that the present invention adopts natural drug Radix Angelicae Sinensis, Herba Artemisiae Annuae, Radix Cirsii Japonici completely, the fragrant strongly fragrant row of Radix Angelicae Sinensis falls apart, the promoting the circulation of blood of enriching blood, invigorating middle warmer has, in row, has benefit, and blood must be supported and be stopped up stagnant faling apart, blood is gentle to skin infection rehabilitation, pain relief; Carbuncle diabrosis is with nourishing blood and promoting granulation.Herba Artemisiae Annuae is specially separated hectic fever due to YIN-deficiency consumptive fever, more pruritus caused by wind pathogen, and only fidgets due to deficiency night sweat, spleen is supported in appetizing, and improving eyesight exorcises evil spirits, and the pain of feeling at ease, treats malignant boil, and removing blood stasis with potent drugs granulation promoting is antibacterial, hemostasis, pain relieving, promotes cellular immunization performance antitumaous effect; Pathogenic fire purging heat, wasting QI-blood not again, the medicine with assistant QI and blood of using.Can monarch can minister can help and make, without toward should not be also.Radix Cirsii Japonici cooling blood and relieving pain, treats carbuncle skin infection, body void after curing the disease.Monarch drug strengthens mutually, the common removing mass detumescence of assaulting fortified position, promoting blood circulation, removing blood stasis and relieving pain, effect of the strong body of nourishing blood and promoting granulation brought into play.Nidus Vespae wind dispelling insecticide, removing toxic substances counteracting toxic substances, blood stasis dispelling relieving convulsion, loose swollen blood stasis dispelling, heart tonifying diuresis, hemostasis analgesic therapy, Xing Yang reduces phlegm, antiallergic, antitumor; Control sore swollen toxin, acute mastitis tumor, scrofula swells and ache, stubborn dermatitis malignant boil, the stiff pain in joint, frightened convulsion migratory arthralgia, the sexual impotence enuresis, and the anaphylactic reaction that may cause with the anti-Resina Toxicodendri of Herba Urticae Cannabinae.The strong body of astragalus root nourishing, tonifying Qi and lifting yang, nourishing kidney spleen reinforcing, strengthening superficial resistance to stop perspiration, the evacuation of pus of holder skin ulcer, detumescence and promoting granulation, protects the liver diuresis; There is enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely; Controlling carbuncle skin ulcer festers, does not close up for a long time and various cancers etc.Semen Strychni (processed) is strengthened mass dissipating and swelling eliminating, removing obstruction in the collateral to relieve pain, and expelling the stasis for the new, activated bone marrow hematopoietic function, antiphlogistic antibacterial, is applicable to various cancerous protuberances.Resina Toxicodendri processed is strengthened removing blood stasis, and hard masses softening and resolving, stimulates the menstrual flow, removing food stagnancy.Fructus Hippophae processed is strengthened promoting blood circulation to remove blood stasis, the chest stuffiness relieving that reduces phlegm, relieving dyspepsia, promoting the production of body fluid to quench thirst, clearing away heat to stop diarrhea, strengthens macrophage function, has resisting fatigue and enhancing body vigor and the special pharmacological performance such as anticancer, and promote wound healing, therefore both can supplement the nutrients, can improve again the resistance against diseases of body.Sal Nitri is strengthened the broken tumor heavily fortified point that disappears, the skin ulcer that disappears eliminating impediment, and pain relieving profit is drenched.This Six-element medicine is minister, coordinates monarch drug mutually collaborative, strengthens curative effect, treating the poisonous disease with poisonous drugs, and toxin expelling eliminating stagnation, strengthening the body resistance, strong body is eliminating evil, pushes away Chen Zhixin, refreshment and brain nourishing.Herba Agrimoniae is adjuvant drug, assists monarch drug relieve internal heat anticancer, cooling blood for hemostasis, the detumescent of healing the wounds, heat-clearing and toxic substances removing, QI invigorating Xing Yang.Herba Urticae Cannabinae is dispeled the wind, invigorates blood circulation, and pain relieving, antiallergic, anticancer swollen pain; The loose painful abdominal mass of the broken knot of Fructus Aurantii, the chest stuffiness relieving of regulating the flow of vital energy, stomach invigorating removing food stagnancy, two medicines are for making to work in coordination with and strengthen monarch drug and play altogether effect of anticancer righting.The mutual Synergistic of said medicine, strengthening vital QI to eliminate pathogenic factors, lifts sun and presses down the moon, hard masses softening and resolving, Yin Yang balancing, inducing diuresis to remove edema, can heat clearing away let out poison, and stasis-dispelling and pain-killing can temperature compensation be carried gas again, and spleen invigorating is dredged stagnant, adjust the five internal organs, fill blood, improve body's immunity, enhancing body anti-cancer ability, i.e. " righting, act sun "; Improve the interior environment of body simultaneously, excite reverse or the extinction of cancerous cell, i.e. " eliminating evil, press down cloudy ", to reach strengthening the body resistance, disappear effect of body Thailand of cancer, this is that " in healthy energy deposits, heresy can not be done." pharmacological effect of the each component of the present invention is as follows:
1, Radix Angelicae Sinensis (Angelica sinensis), nature and flavor are sweet, pungent, warm, GUIXIN, liver, spleen channel.Function cures mainly: nourishing blood and promoting granulation, and promoting blood circulation and stopping pain, the skin moistening of enriching blood, broken heap soil or fertilizer over and around the roots is dredged stagnant, loosening bowel to relieve constipation.Control all cards of blood deficiency, flaccidity syndrome and arthralgia syndrome, menoxenia, amenorrhea dysmenorrhea, lump in the abdomen knot is poly-, bleeding not during menses, asthenia cold abdominalgia, weight, ulcer sores, traumatic injury etc. after dryness of the intestine constipation, bloody dysentery.
2, Herba Artemisiae Annuae (Artemisia carvifolia), is a kind of plant for Compositae artemisia, and nature and flavor bitter, acrid, cold, return liver, gallbladder, three warmers, kidney channel.Function cures mainly: clear deficiency-heat thoroughly, removing heat from blood is except steaming, expelling summer-heat, preventing the attack (or recurrence) of malaria.Control pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat.Studies have reported that, arteannuin has immunoloregulation function, and intravenous injection arteannuin 50-100mg/kg can significantly improve Turnover of Mouse Peritoneal Macrophages phagocytic rate and phagocytic index.Arteannuin also can improve lymhocyte transformation rate, promotes immunization of cell.Artesunate can promote Ts cell proliferation, suppresses TE cell and produces, and stops the release of interleukin and various inflammatory mediators, thereby plays immunoregulation effect, brings into play anticancer usefulness.
3, Radix Cirsii Japonici (Cirsium japonicum Fisch.ex DC), Compositae, artichoke plant, the herb of Ji or root, nature and flavor are sweet, bitter, cool; GUIXIN, Liver Channel.Function cures mainly: cooling blood for hemostasis, blood stasis dispelling eliminating carbuncle, invigorating QI and tranquilization; Control epistaxis, haematemesis, hematuria, have blood in stool, bleeding not during menses, traumatic hemorrhage, carbuncle sore tumefacting virus, body void etc. after being ill.
4, Nidus Vespae is the nest of Vespidae insecticide fruit hornet Polistes olivaceous (DeGeer), the long foot wasp Polistes japonicus Saussure of Japan or different abdomen wasp Parapolybia varia Fabricius.Nature and flavor hardship, salty or sweet, flat.Return stomach warp.Enter bright, the liver of sun, lung meridian.Effect: wind dispelling insecticide, removing toxic substances counteracting toxic substances, blood stasis dispelling relieving convulsion, loose swollen blood stasis dispelling, heart tonifying diuresis, hemostasis analgesic therapy, Xing Yang reduces phlegm, antiallergic, antitumor; Control sore swollen toxin, acute mastitis tumor, scrofula swells and ache, stubborn dermatitis malignant boil, the stiff pain in joint, frightened convulsion migratory arthralgia, the sexual impotence enuresis and anaphylactic disease etc.
5, the Radix Astragali (Astragalus membranaceus (Fisch.) Bunge.), pulse family Astragalus.Nature and flavor are sweet, tepor.Return lung, spleen, liver, kidney channel.Function cures mainly: nourishing and body-strengthening, and tonifying Qi and lifting yang, nourishing kidney spleen reinforcing, strengthening superficial resistance to stop perspiration, the evacuation of pus of holder skin ulcer, detumescence and promoting granulation, protects the liver diuresis.The medicinal history of existing more than 2000 year so far of the Radix Astragali, it has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely; Controlling carbuncle skin ulcer festers, does not close up for a long time and various cancers etc.
6, Semen Strychni (Strychnos nux-vomica Linn), Loganiaceae Strychnos.Nature and flavor hardship, cold, poison, returns liver, spleen channel greatly.Function cures mainly: removing obstruction in the collateral to relieve pain, dispersing swelling and dissipating binds, expelling the stasis for the new, antiphlogistic antibacterial, refreshment, stomach invigorating ventilation, toxic removing removing heat from blood; Control mammary gland tumor, carbuncle pyogenic infections from tumour or sore and swelling and pain due to blood stasis, throat arthralgia pain, mass in the abdomen cancerous protuberance, anemofrigid-damp arthralgia, neural paralysis, myasthenia gravis, poliomyelitis, inappetence, abdominal distention constipation etc.
7, Resina Toxicodendri is Anacardiaceae plant Toxicodendron verniciflnum (Stokes) F. A. Barkley (Rhus verniciflua Stokes) (Toxicodendron vernicifluum(Stokes) F. A. Barkl.) resin through processing after dry product.Nature and flavor are pungent, warm, mild toxicity, return liver, spleen channel.Function cures mainly: removing blood stasis with potent drugs blood, by stagnant long-pending, parasite killing stimulates the menstrual flow.Control women's amenorrhea, blood stasis lump in the abdomen, abdominal pain due to worm stagnation etc.
8, Fructus Hippophae, for the fruit of Elaeangnaceae hippophae plant Fructus Hippophae (Hippophae rhamnoides L.), has another name called fructus hippophae, sour bur.Property acid, puckery, warm.Function cures mainly: promoting blood circulation to remove blood stasis, the chest stuffiness relieving that reduces phlegm, relieving dyspepsia, promoting the production of body fluid to quench thirst, clearing away heat to stop diarrhea.Control and fall damage congestive edema, blood stasis amenorrhea, lung abscess, cough with copious phlegm, stomachache, dyspepsia, enteritis and dysentery, high thermal burn the moon etc.In Fructus Hippophae, flavone can improve SC level, strengthens the function of macrophage, therefore both can supplement the nutrients, can improve again the resistance against diseases of body.In Oleum Hippophae, contain 206 kinds of active substances useful to human body; wherein there are 46 kinds of bioactive substances; contain a large amount of vitamin Es, vitamin A, pyrite etc.; there is resisting fatigue and enhancing body vigor and the special pharmacological performance such as anticancer; protect and accelerate to repair gastric mucosa, increasing intestinal bifidobacteria, falling and subtract plasma cholesterol; anti-curing hyperlipemia and atherosclerosis, and have the effect that promotes wound healing.
9, Sal Nitri, claims again flame nitre, niter etc., is a kind of natural minerals, and main component is potassium nitrate, nature and flavor hardship, cold.Function cures mainly: removing mass is loose hard, and the skin ulcer that disappears is removed painful abdominal mass, blood circulation promoting and blood stasis dispelling, and inducing diuresis to remove edema, fossil profit is drenched, pain relieving.Control a severe pain, chest pain, waist stomachache, furious swelling and ache, eyes is hidden from view, sore throat, dysentery, pouring disease, back of the body cellulitis urticaria etc.
10, Herba Agrimoniae, is the aerial parts of rosaceous plant Agrimony (Agrimonia pilosa Ledeb.), and nature and flavor hardship, cool, returns stomach, liver, spleen, lung, large intestine channel.Function cures mainly: anticancer, the cooling blood for hemostasis of relieving internal heat, the detumescent of healing the wounds, preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances.Control the various heat in blood such as gastric cancer, the esophageal carcinoma, hepatocarcinoma, palace body adenocarcinoma, breast carcinoma, leukemia, hemoptysis, haematemesis, epistaxis hemorrhage, carbuncle, malaria, de-power impairment caused by overstrain etc.
11, Herba Urticae Cannabinae (Nettle) is the root of Urticaceae Urtica plant.Nature and flavor hardship, pungent, temperature; Slightly poisonous.Function cures mainly: dispel the wind, invigorate blood circulation, pain relieving, antiallergic.Swollen pain for cancer, rheumatic ostalgia, urticaria, eczema, snakebite, hypertension etc.
12, Fructus Aurantii, this product is the dry immature fruit of rutaceae Citrus aurantium Linn. (Citrus aurantium L.) and variety thereof.Nature and flavor hardship, pungent, sour, warm, returns spleen, stomach warp.Function cures mainly: dispelling the stagnated QI reduces phlegm, the loose painful abdominal mass of broken knot, and the chest stuffiness relieving of regulating the flow of vital energy, removing food stagnancy stomach invigorating, dredges the stagnant heap soil or fertilizer over and around the roots that disappears.Control the breast side of body stagnation of QI, coerce swollen pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention, the feeling of stuffiness in chest, and eructation, vomiting, heavy after dysentery, gastroptosis, proctoptosis, uterine prolapse etc.
For the mechanism of action, cytotoxicity and the immunologic function of Chinese medicine of the present invention " anticancer righting is loose " are studied, inventor poplar ten thousand springs from 2008 so far, cooperate with medical college department of physiology of Qing Bei national university of Taegu of Korea S, completed usefulness and the effect research to tumor cell at animal model to " anticancer righting is loose ".The various dose for method " anticancer righting is loose " adopting in this achievement in research is processed cancerous cell and mouse macrophage, detect the activity of cell by MTT analytical method, and carry out morphological observation, testing cancerous cell used has lung carcinoma cell, prostate gland cancer cell, hepatoma carcinoma cell, breast cancer cell, macrophage etc.With the cytokine gene expression of real-time polymerase chain reaction fluorescence quantitative PCR detection macrophage, detect the phagocytic function of macrophage with phagocytosis test.Through overtesting, confirm that " anticancer righting is loose " safety range is large, only than using anticancer dosage to exceed under concentration nearly a hundred times, just toxic to cell.Its mechanism of action is that activating macrophage phagocytic function is engulfed cancerous cell, and induced tumor necrosin-a(TNF-a), the generation of the cytokine such as interleukin (IL) 1,6,10 and monocyte chemoattractant protein-1 (MCP-1), thereby suppress tumor growth or promote cancer cell death, bringing into play anticancer centralizing function.
Compared with prior art, the beneficial effect that the present invention has has:
1, Chinese medicine of the present invention does not almost have toxicity to normal cell, only than using anticancer dosage to exceed under concentration nearly a hundred times, just toxic to normal cell.Filled up existing reliable anticancer effect, again without the cancer therapy drug blank of normal cell damage.
2, the technology of the present invention maturation, curative effect are reliable, the kinds cancers such as gastric cancer, hepatocarcinoma, esophageal carcinoma, lymphatic cancer, cerebroma, pulmonary carcinoma, nasopharyngeal carcinoma, uterus carcinoma, breast carcinoma, renal carcinoma, bladder cancer, carcinoma of prostate can be treated, and various early, middle and late phase malignant tumor can be adapted to; Through the clinical trial of part malignant tumor patient, curative effect is reliable.
The advantages such as it is wide that 3, the present invention has medicine source, cheap and easy to get, making is simple, and the suitability is wide, and medical expense is low.If general cancer patient adopts radiotherapy or chemotherapy, the average annual expense of people is more than 100,000 yuan, and uses treatment by Chinese herbs of the present invention, and the average annual expense of people only need be ten thousand yuan of 2-3, are 1/5th of conventional therapies.
Usage of the present invention and consumption: depending on different patients' the state of an illness, each 1-6 gram, every day 3 times, warm water is swallowed, and within 30 days, is 1 course for the treatment of, generally serve on 3 to 6 courses for the treatment of.Some meetings are more longer, the course for the treatment of interval 3-5 days; Whether after symptom, sign disappear completely, take 1 course for the treatment of every half a year, after 3,4 courses for the treatment of, changes into and take every year 1-and carry out after treatment 2 courses for the treatment of, take medicine, depending on the concrete state of an illness later.
Below in conjunction with clinical experiment data declaration therapeutic effect of the present invention:
1, physical data
Inventor collects altogether 100 routine hospitals and is diagnosed as out-patient's (male 68 examples of cancer between year January April to 2011 nineteen ninety, female's 32 examples, age 6-78 year, 40-49 year accounts for 18%, 50-59 year accounts for 20%, 60-69 year accounts for 36%, 70 years old and account for above 12%, be less than 40 years old and account for 14%), wherein gastric cancer accounts for 28%, pulmonary carcinoma accounts for 12%, cerebroma accounts for 10%, hepatocarcinoma and esophageal carcinoma account for 16%, rectal cancer and pancreas cancer account for 10%, uterus carcinoma accounts for 4%, duodenal carcinoma, colon cancer, Gallbladder Adenocarcinoma, breast carcinoma, carcinoma of parotid gland, nasopharyngeal carcinoma, renal carcinoma, bladder cancer, malignant lymphoma, acute lymphoblastic leukemia accounts for 20%.In therapeutic process, observe Chinese medicine of the present invention to gastric cancer, hepatocarcinoma, esophageal carcinoma, lymphatic cancer, cerebroma, curative effect is outstanding especially, and pulmonary carcinoma, nasopharyngeal carcinoma, uterus carcinoma, breast carcinoma, renal carcinoma, bladder cancer curative effect are taken second place, and other cancers are also had to curative effect in various degree.
2, test method
2.1 Therapeutic Method
Matched group oral placebo is stuck with paste rice Fagopyrum esculentum Moench powder, and each 3 grams, every day 3 times, warm water is swallowed, 90 days courses for the treatment of.
The Chinese medicine that the oral specific embodiment of the invention embodiment 1 for the treatment of group makes, each 3 grams, every day 3 times, warm water is swallowed, 90 days courses for the treatment of.
2.2 observation item
Treatment Patients Before And After body weight, blood pressure, routine blood test, anemia, pain, become thin, the variation of weak, edema, inappetence, heating, the symptom such as vomit, have blood in stool.Lab testing cancerous tissue size variation and deterioration situation.Record drug withdrawal patient's situation of surviving after 2 years.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms takes a turn for the better gradually even and to disappear, test chamber checks that cancerous tissue disappears or transfers to optimumly, survives and gradually recovers one's health and have no recurrence for 2 years.
Take a turn for the better: clinical symptom relief, lab testing cancerous tissue stops diffusion or growth, and survival is more than 2 years.
Invalid: clinical symptoms increases the weight of without being clearly better or continuing, lab testing cancerous tissue continues diffusion or growth, dead in two years.
3.2 treatment statistical results are in table 1.
Table 1 liang group curative effect comparison
Group Case (example) Recovery from illness (example) Take a turn for the better (example) Invalid (example) Total effective rate (%)
Treatment group 70 48(68%) 21 1 98
Matched group 30 0(0%) 1 29 3
Visible, the Chinese medicine that the present invention makes can safe and effective treatment kinds cancer.After general patient takes medicine one week, mental status generally takes on a new look, and pain, edema alleviate, and appetite is progressively recovered, and temperature recovery is normal; Continue to take medicine after two weeks, lump dwindles, and disease is day by day alleviated, and blood pressure, hemogram improve, and body weight is gone up, and body constitution strengthens day by day; After three weeks, symptom disappears substantially; After six weeks, energy daily routines, manage household affairs; Adhere to taking 3-6 the course for the treatment of, be 30 days a course for the treatment of, and generally sb.'s illness took a favorable turn, part recovery from illness.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, but is not limited to embodiment.
Embodiment 1
Treat a Chinese medicine for cancer, it is characterized in that by the medical material of following weight parts formulated: 28 parts of Radix Angelicae Sinensis, 28 parts of Herba Artemisiae Annuaes, 28 parts of Radix Cirsii Japonicis, 15 parts, Nidus Vespae, 25 parts of the Radixs Astragali, 17 parts of Semen Strychni (processed)s, 13 parts of Resina Toxicodendri processed, 20 parts of Fructus Hippophae processed, 25 parts, Sal Nitri, 28 parts of Herba Agrimoniaes, 20 parts of Herba Urticae Cannabinaes, 30 parts of Fructus Aurantiis.
The preparation method of this Chinese medicine is that above-mentioned medical material is removed to impurity, dried, after pretreatment, weighs, mixes, pulverizes by described weight portion, sieves by 100 mesh sieves, after packaging, makes.Prescription meets the sanitary standard that the Pharmacopoeia of the People's Republic of China (nineteen ninety-five version one) annex powder general rule requires and Ministry of Public Health specifies.
Wherein the manufacture method of Semen Strychni (processed) is the method that adopts the Pharmacopoeia of the People's Republic of China (version in 1985) to record, and gets sand and puts in pot, after making popular with high heat, add clean Semen Strychni, constantly stir, scald to heaving and aobvious sepia or dark-brown, take out, sieve removes sand, cools for subsequent use.
Wherein the manufacture method of Resina Toxicodendri processed is to adopt the method for recording in " handbook is concocted in Chinese herbal medicine processing " (.1971.12. of the Shandong People's Press first edition), Resina Toxicodendri knock fritter, puts in iron pan and is fired to and is bulk shiny black bulk, takes out, and cools for subsequent use.
Wherein the manufacture method of Fructus Hippophae processed is: get sand and enter after iron pan intense fire is made popular to add clean Fructus Hippophae, constantly stir, scald to the aobvious brown of epidermis or dark-brown and take out, sieve removes sand, for subsequent use by drying after Fructus Hippophae rapid water rinsing.
The Chinese medicine scope of application of the present invention: various early, middle and late phase malignant tumor, precancerous lesion, immunization therapy, operation, radiotherapy, chemotherapeutic period and anaphase thereof.As by Chinese medicine of the present invention and some chemical drugs use in conjunction, in treatment, play synergism, and can alleviate the toxic and side effects of chemotherapeutics.Chinese medicine of the present invention can improve the hemogram after schistosomicide liver damage and chemotherapy, without cytotoxicity such as alopecia, oral ulcer, bone marrow depression.
Embodiment 2
Treat a Chinese medicine for cancer, it is characterized in that by the medical material of following weight parts formulated: 15 parts of Radix Angelicae Sinensis, 15 parts of Herba Artemisiae Annuaes, 15 parts of Radix Cirsii Japonicis, 10 parts, Nidus Vespae, 15 parts of the Radixs Astragali, 15 parts of Semen Strychni (processed)s, 10 parts of Resina Toxicodendri processed, 15 parts of Fructus Hippophae processed, 20 parts, Sal Nitri, 20 parts of Herba Agrimoniaes, 15 parts of Herba Urticae Cannabinaes, 40 parts of Fructus Aurantiis.All the other are with embodiment 1.
Embodiment 3
Treat a Chinese medicine for cancer, it is characterized in that by the medical material of following weight parts formulated: 30 parts of Radix Angelicae Sinensis, 30 parts of Herba Artemisiae Annuaes, 30 parts of Radix Cirsii Japonicis, 20 parts, Nidus Vespae, 30 parts of the Radixs Astragali, 20 parts of Semen Strychni (processed)s, 15 parts of Resina Toxicodendri processed, 25 parts of Fructus Hippophae processed, 30 parts, Sal Nitri, 30 parts of Herba Agrimoniaes, 30 parts of Herba Urticae Cannabinaes, 40 parts of Fructus Aurantiis.
The typical case who enumerates treatment below falls ill:
Case 1: Li Xiangyu, female, 50 years old, lie up in Nujiang Autonomous Prefecture of Yunnan Province the People's Hospital.Cause hematemesis repeatedly, melena 5 days, in Zhu No.1 Hospital Attached to Kunming Medical College in April 11 nineteen ninety.Previously there are " ulcer of upper digestive tract " history of repeated attack 8 years; Gastrorrhagia 5 times, is in hospital 3 times.Have a medical check-up: ordinary circumstance is poor, dyscrasia, critical sickly complexion, 34 kilograms of body weight.Cardiopulmonary are without extremely; Epigastrium tenderness is obvious, and liver spleen is without enlargement, sign of ascites feminine gender.After being admitted to hospital, hemoglobin is the decline of carrying out property, when minimum, can reach 3.5g/dl.Gastroscope (#900590) diagnosis: 1, gastric cancer; 2, duodenal bulbar ulcer (cicatricial phase); Sick inspection (#90-2600) is diagnosed as poorly differentiated adenocarcinoma, signet-ring cell carcinoma.Row " stomach radical correction " a course for the treatment of of systemic chemotherapy, improvement is left hospital.After leaving hospital, because of the resistance to chemotherapy of can't stand, impose Chinese medicine of the present invention " anticancer righting is loose " oral, each 2 grams, every day 3 times, after half a year, change into and monthly take 2 weeks.Physical rehabilitation after 1 year, can manage household affairs, after change each 1 gram into, every day 2 times, take medicine every half a year 1 week, check gastroscope and sick inspection to nineteen ninety-five to former operation hospitals, result is cured and drug withdrawal completely.So far follow up a case by regular visits to patient alive, and also manage household affairs.
Case 2: Yang Yanzhen, female, 41 years old, Xin Tun town, Dali Prefecture, Yunnan Province Heqing County Red Star village peasant.Because continuing the right hypochondrial region hot first quarter moon that occurs together, in Lai Heqing County the People's Hospital treatment Mays 22 in 1997.Before patient's first quarter moon, because of busy farming season fatigue Hou Ganyoulei district persistence distending pain, twinge, be the aggravation of carrying out property, pain is to homonymy shoulder, arm radiation, and to making limb activity limited, when upright or flat crouching, pain more so, can not alleviate by general antipyretic analgesic.Occur together heat, poor appetite, weak, gradual becoming thin, facial edema etc.Local diagnosis " liver abscess ", infusion heavy dose " ampicillin, micronomicin, metronidazole " and the Supporting Therapy more than 10 days of suiting the medicine to the illness are invalid.Previously there is " schistosomicide " history, ediblely salt down for a long time, cured saline taste product.Have a medical check-up: 38.3 DEG C of T, 96 beats/min of P, 24 beats/min of R, BP 110/70mmHg.Shallow complexion, facial edema, anemia looks, chronic pain sickly complexion, 43 kilograms of body weight, right front flexing position, walks with difficulty.Light red tongue purple, white and thin fur, wiry and frequent pulse.Cardiopulmonary are normal.Right hepatic region tenderness, kowtow pain, the liver upper bound rises to right midclavicular line the 4th intercostal space, the flat arcus costarum lower edge of lower bound.Blood RBC 3.6 × 10 12/ L, HGB 95g/L, WBC 10.3 × 10 9/ L; Liver function is normal, HBsAg feminine gender, AFP strong positive; Two is just normal; B ultrasonic (#19524) is shown in that liver form is regular, density unevenness, have an appointment the slightly low echo area of 33 × 25mm of right hepatic region, internal echo inequality, prompting: 1, schistosomicide hepatic injury; 2, right lobe of liver reality enclosed mass character is undetermined; Chest just, side position X-ray film (#30134) shows: right diaphragm raises, and considers canceration under diaphragm.First visit: primary hepatocarcinoma (inflammatory type), impose each 5 grams of Chinese medicine of the present invention " anticancer righting is loose ", every day 3 times, swallow with Radix Artemisia ordosicae soup, be aided with to the ill Supporting Therapy 1 week, symptom slightly alleviates, May 28 to Lijiang City examination in hospital, liver function was normal, HBsAg feminine gender, B ultrasonic (#1982) is shown in part spy and approximately slightly low echo area of 20 × 20mm of size in the right back leaf of liver, owe clearly with boundary around, liver size and form is normal, and the increasing of essence echo is slightly latticed change, skewness, prompting: 1, slightly low echo area (character is undetermined) of the right back leaf of liver; 2, schistosomicide liver damage ultrasonogram; 3, slightly enlargement of spleen.Treatment 1 week before continuous, symptom and spirit are further improved, and appetite increases.Clarified a diagnosis to Dali prefecture the People's Hospital June 3, CT scan (#10247) is shown: hepatomegaly, the low-density kitchen ranges such as the visible approximately 4 × 4cm size of right lobe of liver epimere, after CE, show heterogeneity strengthening, through delayed sweep, focal zone still shows a cryptomere low-density kitchen range, and in capsule, CT value is 21Hu, diagnostic comments " hepatocarcinoma, suggestion is done AFP association and examined "; AFP was put and was exempted from testing result higher than normal value June 6.Before continuous, treat to further consultation on June 13, symptom disappears substantially, and diet approaches normal, still feels weak.Look into: AFP, without kowtowing pain, is surveyed weak positive in hepatic region.Before continuous, treat to further consultation on August 15, the further rehabilitation of health, can be engaged in general housework.Look into: liver upper right circle recovers normal; Blood RBC 4.2 × 10 12/ L, HGB 116g/L, WBC 4.6 × 10 9/ L, PLT 259 × 10 9/ L; Liver function is normal, AFP feminine gender.B ultrasonic shows: the slightly low echo area of the right former 33 × 25mm in hepatic region disappears.Continuous " anticancer righting is loose " decrement, to each 3 grams, every day 3 times, arrives Dali prefecture the People's Hospital on the 6th to JIUYUE and checks, CT(#10247) to show: liver parenchyma density is normal, shows homogeneous strengthening after CE, and with CT comparison on June 3, the low-density such as lobus dexter disappear.Continuous with " anticancer righting is loose " drug withdrawal after 1 week.Disease is fully recovered, follows up a case by regular visits to so far, alive without uncomfortable, participates in field and housework always.
Case 3: Yang Xiuqian, female, 62 years old, the retirement of personnel bureau of Di-qing County, Yunnan Wei Xi county.Because making a definite diagnosis " liver metastases cancer " April, in Lai Heqing County the People's Hospital treatment October 13 in 1997.Patient from 1992 in Dali prefecture the People's Hospital row " duodenum sarcoma " excision; Again live former operation hospitals June in the same year " find epigastrium enclosed mass January remaining ", through CT(#10277) and put and exempt from AFP and measure and make a definite diagnosis.Due to " lump is huge, and liver left and right leaf all involves, and has lost opportunity of operation ", leave hospital through systemic chemotherapy.The postabdomen enclosed mass of leaving hospital continues to increase, and in the JIUYUE row secondary chemotherapy of being again in hospital, color ultrasound is shown during this time: liver enlargement, and the multiple Space Occupying Solid Lesion of liver, wherein maximum one is 13 × 9.7cm.After end of chemotherapy is left hospital, giddy, tinnitus, weak, bitter taste, upper abdomen Men Zhangjilei district distending pain, sled pain increase the weight of day by day, so that limitation of activity, anorexia.Ordinary circumstance is poor, and shape is thin sallow, exhaustion, dyscrasia, 35 kilograms of body weight.Crimson tongue purple, tongue is stripped off, stringy and thready pulse, cardiopulmonary are normal.Epigastrium protuberance, can touch approximately 25 × 18 × 6cm essence enclosed mass.Blood RBC 3.33 × 10 12/ L, HGB 97g/L, PLT 99 × 10 9/ L, WBC 3.3 × 10 9/ L, GRA 48%; Two is just conventional normal; Liver function is normal, HbsAg feminine gender.B ultrasonic (#349) shows: liver parenchyma Echo heterogenicity matter, in it, there are multiple low echo areas that differ in size, and maximum twoth district are respectively 173 × 98mm, 88 × 68mm.Hospital informs that family members patient is unlikely to survive several months, for it prepares funeral affairs.Impose Chinese medicine of the present invention " anticancer righting is loose " oral, each 3 grams, every day 3 times, patient's symptom fades away, and it is normal that diet recovers, and can manage household affairs.In therapeutic process, repeatedly to do B ultrasonic and observe, carrying out property of liver enclosed mass is dwindled.Further consultation again on November 26 in 1997, patient does not tell discomfort.Look into: epigastrium enclosed mass is reduced to 12 × 8.5 × 2.5cm, B ultrasonic (#719) shows: in liver, maximum two low echo areas are respectively 104 × 95mm, 87 × 56mm.Before continuous, treat more than half a year, after 6 years, patient is dead.
Case 4: Zhao Kechun, man, 67 years old, Heqing Party school of county Party committee left one's post.Find cervical region Silent Neuritis lump more than 7 years, successively on April 11st, 1996 to DaLi Medicine Academy, (sick inspection #960334) and on January 15th, 1998 were carried out check pathological section to the Kun Yifu First Academy (sick inspection #97-9), were diagnosed as " Non-Hodgkin ' sMalignant Lymphomas ".Carry out local enlarged lymph node excision for several times therebetween, imposed chemotherapy simultaneously.Each chemotherapy tumor all after of short duration control, is recurred again and spread and carrying out property increases the weight of, in Lai Heqing County the People's Hospital treatment Augusts 10 in 1998.Patient's ordinary circumstance is poor, right side cervical region can touch the lymph node that several Semen Castaneaes are differed in size to Semen arachidis hypogaeae sample, matter is hard, rough, edge adhesion, restriction of neck motion, imposes Chinese medicine of the present invention " anticancer righting is loose " oral, each 1.5 grams, 3 treatments every day, a further consultation in month, diet and mental status take a turn for the better, lump deliquescing and without continue increase, cervical region activity makes moderate progress, continuous with " anticancer righting is loose " 3.0 grams, every day 3 times, Radix Artemisia ordosicae soup is swallowed, treatment is looked into lump after three months and is contracted to Semen Glycines size continuously, and matter is soft, and cervical region activity freely.Disease has been fully recovered and has not been recurred, alive so far.

Claims (2)

1. treat a Chinese medicine for cancer, it is characterized in that by the medical material of following weight parts formulated: Radix Angelicae Sinensis 15-30 part, Herba Artemisiae Annuae 15-30 part, Radix Cirsii Japonici 15-30 part, Nidus Vespae 10-20 part, Radix Astragali 15-30 part, Semen Strychni (processed) 15-20 part, Resina Toxicodendri 10-15 part processed, Fructus Hippophae 15-25 part processed, Sal Nitri 20-30 part, Herba Agrimoniae 20-30 part, Herba Urticae Cannabinae 15-30 part, Fructus Aurantii 25-40 part.
2. a kind of Chinese medicine for the treatment of cancer according to claim 1: it is characterized in that by the medical material of following weight parts formulated: 30 parts of 28 parts of Radix Angelicae Sinensis, 28 parts of Herba Artemisiae Annuaes, 28 parts of Radix Cirsii Japonicis, 15 parts, Nidus Vespae, 25 parts of the Radixs Astragali, 17 parts of Semen Strychni (processed)s, 13 parts of Resina Toxicodendri processed, 20 parts of Fructus Hippophae processed, 25 parts, Sal Nitri, 28 parts of Herba Agrimoniaes, Herba Urticae Cannabinae 20, Fructus Aurantii.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107837317A (en) * 2017-11-30 2018-03-27 青岛大学 A kind of medicine for treating cancer and inflammation
CN115282247A (en) * 2021-12-31 2022-11-04 杨杰 Traditional Chinese medicine for treating advanced cancer and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1073866A (en) * 1992-08-09 1993-07-07 付耀华 Oral liquid for curing cancer and compound method thereof
CN101543616A (en) * 2009-04-21 2009-09-30 闫树清 Traditional Chinese medicine composition for preventing and treating tumor and its preparation method
CN102274361A (en) * 2011-07-29 2011-12-14 李丰曹 Anticancer medicinal composition and preparation method of decoction thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1073866A (en) * 1992-08-09 1993-07-07 付耀华 Oral liquid for curing cancer and compound method thereof
CN101543616A (en) * 2009-04-21 2009-09-30 闫树清 Traditional Chinese medicine composition for preventing and treating tumor and its preparation method
CN102274361A (en) * 2011-07-29 2011-12-14 李丰曹 Anticancer medicinal composition and preparation method of decoction thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107837317A (en) * 2017-11-30 2018-03-27 青岛大学 A kind of medicine for treating cancer and inflammation
CN115282247A (en) * 2021-12-31 2022-11-04 杨杰 Traditional Chinese medicine for treating advanced cancer and preparation method thereof

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