CN106668525A - Hui-nationality traditional Chinese medicine caterpillar fungus oral solution for treating leukemia and preparation method thereof - Google Patents
Hui-nationality traditional Chinese medicine caterpillar fungus oral solution for treating leukemia and preparation method thereof Download PDFInfo
- Publication number
- CN106668525A CN106668525A CN201510749378.6A CN201510749378A CN106668525A CN 106668525 A CN106668525 A CN 106668525A CN 201510749378 A CN201510749378 A CN 201510749378A CN 106668525 A CN106668525 A CN 106668525A
- Authority
- CN
- China
- Prior art keywords
- traditional chinese
- chinese medicine
- cancer
- medicine
- hui
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention provides a formula and preparation method of a Hui-nationality traditional Chinese medicine caterpillar fungus oral solution for treating leukemia. The medicine is a green and high-tech traditional Chinese medicine for treating the leukemia. The Hui-nationality traditional Chinese medicine caterpillar fungus oral solution is a traditional Chinese medicine oral solution prepared by mixing traditional Chinese medicines including herba sarcandrae, 30g of radix sophorae subprostratae, tulip bulb, radix isatidis and the like at a certain ratio, adding water and decocting, extracting and concentrating. The Hui-nationality traditional Chinese medicine caterpillar fungus oral solution is used for mainly treating the leukemia and can also be used for treating digestive system cancers including pharyngolaryngeal cancer, gastric cancer, colorectal cancer and the like. The Hui-nationality traditional Chinese medicine caterpillar fungus oral solution has the characteristics of a few of medicines and moderate dosage; modern medicine pharmacological experiments of most of the selected medicines show that the medicines can be used for treating the cancer; the physical function is radically improved at relatively low cost; the deterioration of diseases is prevented and the body health is recovered.
Description
Technical field
Hui ethnic group's Chinese medicine Chinese caterpillar fungus leukemia recovery oral liquid according to the present invention is a kind of leukemic green high-tech of prevention and treatment
Skill Chinese herbal medicine.The invention further relates to the preparation method of the medicine, belongs to traditional Chinese medicine class.
Background technology
According to《China's tumour registration annual report in 2014》Data display, according to China for each person 74 years old life-span calculate, China
The probability that people suffers from malignant tumour in all one's life is 22%, and average minute clock has 6 people to be diagnosed as malignant tumour, tumour China into
For a kind of common disease.At present the cancer patient of China is about ten thousand people more than 800, and every year with the speed of more than 100 ten thousand people in increase
(Also have data to show every year is being increased with the speed of 3,120,000 people).And the whole world
According to statistics, in the cancer patient of China nearly 8,000,000, although the leukemic incidence of disease and number of the infected are not also front 10
Position, accounts for the 5/100000 of population per annual morbidity, every year the people of about 8-9 ten thousand, but the death rate but and come top ten lung cancer,
The same height of the carninomatosis such as liver cancer, breast cancer, which results in many patients lose to live confidence.Leukaemia is due to pernicious thin
Born of the same parents clone constantly breeds without limit, and a large amount of proliferative cells have spatially tied up ossis, as a result causes marrow failure and complete
Body histoorgan is done harm to by leaching, such as acid of the same race because leukaemia can produce some body fluid inhibiting factorsFerritin
Etc. (isoferritin) suppress normally to makeHaemocytePropagation, thus just generate clinical a series of sings and symptoms.And most
Terribly be that while that some people's household economy are not short of money, but due to national all of tumour hospital people all the year round it is full
To suffer from, thus the bed of a treatment can be got, the regular treatment of some famous expert hospitals can be enjoyed --- including excessively controlling
Treat --- leukaemic or relatively little of, addLeukemic treatmentRelatively difficult, it is thin that many also needs to Hematopoietic Stem
Born of the same parents' transplanting, Umbilical Cord Blood Transplant,Gene therapyDeng, so just more make it is many still have existence leeway leukaemics add
Speed has moved towards dead road.
Leukemic pathogenic factor substantially has three, and one is chemical factor, and this reason may not be common, because premise is necessary
It is some chemicals of patient's Long Term Contact, such as benzene, affirmative is compared in the cause leukaemia effect of benzene.Benzene causes acute leukemia with acute grain
Based on chronic myeloid leukemia and erythroleukemia.Two is inherent cause, and this pathogenic factors is not also proved so far, clinically why this
The reason for thinking, is have leukaemia family history person to account for percentage eight in leukaemic, so can not the reason for be relatively common
Ignore.Three is virus, and if patient is in early stage other are suffered fromDiseaseIf, such as some tumours, at this time it is possible to generation
Leukaemia, because the homologous gene of most vertebrate is all source tumor gene, this is also the leukemogenic cause of disease
One of.Although leukemic pathogenic factor clinically also has many disputes, above-mentioned three kinds are relatively common.
It is to carry out regular chemotherapy to regular large hospital to treat leukemic best method at present, and the cure rate of ALL can
50% is also can reach with the cure rate for reaching more than 80%, ANLL.The incurable chronic myelocytic leukemia patient of those chemotherapy,
By Hemopoietic Stem Cell Transplantation, can also also there is the healing of 50%-60% possible.But various treatment technologies have it certainly again
Body advantage and deficiency, such as HSCT technology, can make the high-risk or recurrent and refractory leukaemia that cannot cure over
Patient obtain cure chance, but have it is expensive, cause the deficiencies such as rejection;And chemotherapy, chemotherapy not only large side effects,
Patient suffering is difficult to stand, and needs the time of several years, and success rate is nor 100% ...
Leukaemia is a kind of malignant tumour of general.Traditional Chinese medicine has no leukemic name of disease, but with regard to belonging to " blood its clinical manifestation more
The category such as card ", " deficiency of blood ", " consumptive disease ", " evil core ".Leukaemia is disease more more refractory at present, but refractory representative cannot
Can control, in addition to above-mentioned western medical treatment method, the traditional Chinese medical science also there are many effectively treatment methods.Existing clinical proof Chinese medicine is to this disease
Curative effect relaxes to be stablized, and can reduce the toxic and side effect of chemotherapy, does not produce resistance, and leukemic each phase can be applied.The traditional Chinese medical science is with entirety
Idea goes for various each phase cancer according to the whole body feature diagnosis and treatment of patient.The advantage of Chinese medicine cancer exists
In being conducive to stablizing the state of an illness, toxic and side effect is slight, symptom improves more apparent, slow down PD, tumor regression or band knurl compared with
Long term survival, patient is easy to receive and expense is than less expensive.At present doctor trained in Western medicine is also considered as traditional Chinese medicine can control as the auxiliary of cancer
Treat, contribute to reducing the toxicity of Radiotherapy chemotherapy, improve cancer related symptoms, improve life quality, extend life cycle.But exist
Problem is that the prescription uniformity of the traditional Chinese medical science is poor, treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, chosen
Medicine is all not by modern medicine pharmacology reality always --- majority is more than more than half --- in herbal medicine medicinal material
" compatibility " medicine of " diagnosis and treatment based on an overall analysis of the illness and the patient's condition " that prove function for cancer and effect is tested, inventors believe that very improper;And folk prescription,
Folk prescription cure the disease lean on be test, often stop over the time cured the disease.
The content of the invention
The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and in the side's of curing the desease poor consistency, repeatability
Poor, high level evidence-based medicine EBM is theoretical and evidence is relative lacks, thus the situation for mainly waiting deficiency by rule of thumb for cancer, proposition one
The new dosage of kind and preparation method, there is provided one kind reduces the leukemic incidence of disease from the beginning of prevention, starts to subtract from canceration
Delaying its tempo induction induces its apoptosis or differentiation to revert to the green high-tech Chinese herbal medicine of normal cell, with very low flower
Take, fundamentally improve physical function, so as to get well.Its sharpest edges are to greatest extent to induce cancer cell certainly
My apoptosis and differentiation, promote it progressively to recover normal condition.In specific formula, also coordinate diagnosis and treatment based on an overall analysis of the illness and the patient's condition, according to leukaemia
Origin cause of formation system " blood trouble ", " deficiency of blood ", " consumptive disease ", " evil core " the features such as, according to the concrete condition of patient, different matching somebody with somebody is respectively adopted
Just, with the method for strengthening vital QI to eliminate pathogenic factors adopting both clearing heat method and tonification method, or boosting qi and nourishing yin, strong spleen and liver, or enriching kidney essence, strengthening spleen, tonifying kidney, or heat-clearing solution
Malicious, promoting blood circulation and removing blood stasis, or strengthening the spleen and stomach, strongly invigorating QI and blood ... accomplish not hindering clearly just, benefit does not stay heresy, it is clear in have benefit, giving consideration to both the incidental and fundamental, phase
It is auxiliary to coordinate, create a good internal environment to hemopoietic system, to accelerate the recovery of hematopoiesis function, with correct in healthy tendency it is empty,
The solidifying poison of heresy is poly- and internal organs imbalance of yin and yang function reduces the deficiency that disequilibrium causes immunologic hypofunction, adjusts and improve exempting from for body
Epidemic disease function, to reachAdopting both clearing heat method and tonification methodThe purpose of overall suppression disease, so as to improve the overall curative effect and late result of leukemia treating, be
Leukaemic is provided in a kind of green high-tech that function for cancer and effect are proved by modern medicine pharmacological evaluation
Herb formulation and compound method, with very low or relatively low cost, fundamentally improve physical function, the deterioration of symptom management
And make the state of an illness gradually take a turn for the better, finally recover healthy.Thus also to patient one according to the personal state of an illness, economic situation, individual
Wish selects different treatment methods or several method to share particularly traditional Chinese and western medicine to combine complex treatment application to consider
Leeway, to obtaining optimum curative effect, easily improves survival rate --- particularly more than 5 years survival rates.
Technical scheme proposed by the invention is:
First, leukemic Hui ethnic group's Chinese medicine Chinese caterpillar fungus leukemia recovery oral liquid of described prevention and treatment and preparation method thereof, is by following
Made by the weight proportion of raw material:
Cordyceps sinensis 10g, Glabrous Sarcandra Herb 30g, purple mound 10g, edible tulip 5g,
Radix Isatidis 15g, subprostrate sophora 30g, bush 15g, Radix Astragali 15g,
Thunder godvine 3g, Ligusticum wallichii 5g, Radix Glycyrrhizae 5g
This side is substantially square for one decoction on the one.In practical application, can also be increased according to the physique of patient and conditions
Theoretical " dialectical compatibility " medicine of the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert ".
In view of with this, basic side's decoction decoction of medicinal ingredients amount is big, taste is not good enough, patient is difficult to drink, therefore must apply special process
It is prepared.
2nd, it is by the preparation method that above-mentioned each raw material makes traditional Chinese herbal decoction of the present invention:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to Cordyceps sinensis, Radix Glycyrrhizae, all amplify 10 times, clean water
Afterwards, BT-2 stainless steels are placed in extract in kettle, plus after 7-9 times of running water, 100 DEG C of constant temperature are heated to and are extracted 1.5-2 hours, separated
Extract, pressure filtration, filtrate is standby.
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract half an hour
Left and right, extraction fluid, pressure filtration, filtrate is standby.
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes
Left and right, extraction fluid, pressure filtration, filtrate is standby.
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg),
80 DEG C are heated to, 870-910ml is concentrated into, it is standby.
(3), powder processed
Cordyceps sinensis 10g, Radix Glycyrrhizae 5g are respectively amplified 10 times, it is end together to crush, and crosses 100 mesh sieves, standby in being fitted into 0.5g capsules
With.
B, packaging
A. in the concentrate for preparing being fitted into vial or vinyon bottle, every bottle of 30ml, mounted box, vanning, sterilizing (are adopted
60Co irradiation is used, irradiation dose is 8kGy).
B. in capsule being fitted into vial or vinyon bottle, mounted box, vanning, sterilizing (adopt 60Co irradiation, irradiation
Dosage is 8kGy).
, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Routine instructions of taking of the invention:Above-mentioned decoction three times a day, 1 bottle every time(30ml), administered at empty stomach use;Each take soup
10 capsules are taken while agent.(taking half an hour after can not drink water in a large number, in order to avoid water down liquid).Do not eat during medication pungent
The peppery grade food larger to gastrointestinal irritation.
The effect of each raw material of the present invention:
Cordyceps sinensis, Cordyceps sinensis is a kind of traditional famous and precious nourishingChinese medicineMaterial, there is regulation function of immune system, antitumor, anti-
Fatigue etc. is variousEffect.The main component of Cordyceps sinensis include cordycepic acid, cordycepin, amino acid, sterol, mannitol, alkaloid,
Vitamin B1, B2, polysaccharide and mineral matter etc..The effects such as with anticancer, nourishing, immunological regulation, antibacterial, tranquilizing soporific.Tradition
Medical science《The new compilation of materia medica》Record:" sweet warm in nature, secret lean gas, specially mends the gate of vitality." modern medicine study confirmation, its composition is containing fat
Fat, protamine, smart fiber, cordycepic acid, CORDYCEPS element and vitamin B12 etc..Cordyceps sinensis is usually used in antitumor, raising immunity,
Cell ability is improved, improves cardiac function, adjust respiratory system, renal function improves hematopoiesis function, adjusts blood fat, modulability
Function etc..Wherein antitumous effect and raising immunologic function are used for simultaneouslyIt is clinicalMalignant tumourTreatmentGood effect can be obtained
Really.Cordyceps extract has in vitro clearly suppression, the effect of killing tumor cell.Contain Chinese caterpillar fungus in Cordyceps sinensis
Element, is the main component of its performance antitumor action.Clinically adjuvant therapy of malignant tumor mostly is using cordycepin,SymptomObtain
Improve more than 91.7%;It is mainly used in rhinocarcinoma, pharynx cancer, lung cancer, leukaemia, the patient of the cancer of the brain and other malignant tumours.Very
Many antineoplastic Chinese traditional medicines are also made by with Cordyceps sinensis as primary raw material, such as clearing lung-heat Sanjie Pill, can to improve immunologic function
While inhibition cancer cell.
Glabrous Sarcandra Herb, nature and flavorEffect:Taste is pungent, it is mild-natured.It is clearing heat and detoxicating, dispelling wind and eliminating dampness, promoting blood circulation and stopping pain.It is clinicalUsing:It is applied to
Kinds of tumors, the such as cancer of the esophagus,Cancer of the stomach, colon and rectum carcinoma, cancer of pancreas, liver cancer, acute leukemia etc..
It is purple abundant, another name:Radix macrotomiae (common name), mountain Asian puccoon, red stone root.Nature and flavorEffect:Bitter, it is cold in nature.Cooling and activating blood, heat-clearing
Removing toxic substances, laxation defaecation.Applicable kinds of tumors, such as chorioepithelioma,UterusCancer, liver cancer, lung cancer, leukaemia.
Mountain is kind to eat, and nature and flavor are sweet, pungent, cool, mild toxicity.Return liver, kidney, lung, stomach,Large intestine channel.Drug effect:Internal heat anticance,DetumescenceDissipating bind.It is clinicalUsing:Suitable for kinds of tumors, it is mainly used inBreast cancer, also for malignant lymphoma, thyroid cancer,SkinCancer,Uterine neck Cancer, nasopharyngeal carcinoma, the cancer of the esophagus, leukaemia,Cancer of the stomachDeng.Additionally, applying also for carbuncle swells serious case of furuncle, scrofula, snake bite and benign swollen
Knurl, such as thyroid adenoma, cystic hyperplasia of mammary gland, mammary gland fibroma, hemangioma.It is medicinal(1)Internal heat anticance, for carcinoma product poison.
Radix Isatidis, Radix Isatidis is bitter, trembles with fear.The thoughts of returning home, stomach.Effect is clearing heat and detoxicating, cool blood, profit pharynx.Its chemical composition is:Ancient name for Chinese cabbage
Blue root containing indigo, indigo red, cupreol,PalmAcid, uridine, hypoxanthine, uracil,Indigo naturalisKetone and daucosterol etc..Its
Pharmacological action is:This product is equal to various gram-positive bacterias, Gram-negative bacteria and influenza virus, arboviruse, parotid gland virus
There is inhibitory action.Improving immunocompetence;There is obvious antipyretic response.Indigo red contained by this product has significant anti-leukocythemia to make
With;Banlangen Polysaccharide can reduce the content of animal used as test serum cholesterol and triglycerides, and reduce MDA contents, so as to prove
This product Wheat Protein.
Subprostrate sophora, beLegume root of subprostrate sophoraRoot.Bitter cold in nature.Effect is to relieve inflammation or internal heat, detoxifying, subsiding a swelling, pain relieving.Cure mainly:
Laryngalgia, sore-throat,Larynx numbness,Swelling and aching of gum,Breathe heavily fullHeat is coughed,Jaundice, diarrhea, heat is swollen,Mange, snakeworm dog bite.Its is rightThe cancer of the esophagus、Nose Pharynx cancer, cervical carcinoma,Carcinoma of urinary bladder, leukaemia have inhibitory action.Composition pharmacology:Containing TA about 0.93%, whereinMatrine
(Matrine) 0.52%,Oxymatrine(Oxymatrine) 0.35%, Yi JihanD-maackianin-β-D-glucoside(Sophoraponicin)、Red sandalwood
Plain (Pterorepine),Screw oil expeller axleGrass roots glucoside (TrifolirhiZin),Albizzia kalkoraPlain (Maackian), sophoradin (Sophra)
Deng.DNA and RNA synthesis of the subprostrate sophora to tumour cell has obvious inhibitory action, so as to block the propagation of tumour cell, can promote
Enter lymphocyte transformation, excite or strengthen the CDCC of lymphocyte, improve T cell ratio, strengthen or adjustment macrophage is thin
Born of the same parents' phagocytic function, moreover it is possible to adjust endocrine, strengthens adrenocortical function, thus affects the occurrence and development of tumour.
Bush, nature and flavorEffect:It is sweet, salty, mild-natured.Promoting circulation of blood broken stasis of blood, swelling and pain relieving.It is clinicalUsing:This product is closely used to disappear
Change road arsine knurl andCervical carcinoma、Oophoroma, liver cancer and chronic myelogenous leukemia.Additionally, being additionally operable toTreatmentAmenorrheaStomachache、PostpartumThe stasis of blood
Blood, suffer from abdominal pain uncomfortable in chest, traumatic injury, knife wound bleeding, icteric hepatitis, La diseases, orchitis,Anaemia, afterpains.Furuncle pain, urine
Road feel dye, renal shutdownPain in the back, chronic enteritis, enterorrhagia, haematemesis etc..
The Radix Astragali, the Radix Astragali is sweet, tepor.Returns spleen, lung channel.Tonifying spleen lung qi, yang invigorating, benefit defends solid table, diuresis, eliminating toxic life
Flesh.The Radix Astragali is the dry root of legume astragalus mongolicus Astragalus membranacus.It is sweet containing amino acid, mucilaginous substance, carbohydrate, bitter principle, choline
Dish alkali folic acid, kumatakenin, cupreol(, astragalus polyose etc..It is allCancerPatient is white because of spleen-lung Qi deficiency caused complexion white light, burnout
It is powerless, receive few loose stool, hematemesis hematochezia, cough and asthma shortness of breath, abundant expectoration is dilute white, deficiency of QI with disinclination to talk, weak spontaneous perspiration, palpitation and insomnia, fever due to deficiency of vital energy,
Edema oliguria etc. can use it.The Radix Astragali can strengthen the phagocytic function of reticuloendothelial system, there is facilitation to interferon system, right
Cancer patient lymphocytes' function has completeness Immunonormalizing action, has fabulous curative effect to precancerous lesion gastric ulcer.
Thunder godvine, effect:Dispelling wind and eliminating dampness, promoting blood circulation and removing obstruction in channels, swelling and pain relieving, desinsection removing toxic substances.Cure mainly rheumatoid and rheumatism
Property arthritis, glomerulonephritis, nephrotic syndrome, intractable headache bodily pain, lupus erythematosus, Behcet's disease, psoriasis, leprosy,
Eczema, scabies, stubborn dermatitis, venomous snake bite.One of effect of thunder godvine antitumor action:It is thin that triptolide can resist human leukemia
Born of the same parents system m cangue soft-fractrue rock mass.Triptolide also has therapeutic action to various solid tumors.In vitro to Hela, KB, SG7901
There is lethal effect etc. several human cancer cells.Triptolide is that one kind belongs to cycle non-specific antineoplastic, mainly
Inhibit the synthesis of DNA.NSC-163063 has obvious antitumor activity to mouse leukemia L1210, and L615 leukaemia can be made little
Mouse long-term surviving.Tripterygone has inhibitory action to the human nasopharyngeal carcinoma KB cells of in vitro culture.
Ligusticum wallichii, nature and flavorEffect:Taste is pungent, slight bitter, property intestines trail temperature.Blood-activating and qi-promoting, wind-expelling pain-stopping.Chemical composition:Containing biology
The phenolic substances such as alkali, forulic acid, also, chuanxingol, Diligustilide, ligustrazine, trimethylamine hydrochloride, choline hydrochloride etc..This
Outward, Rhizome of Ligusticum Sinense Oliv. Cv. Chuanxiong still contains neutral oil, its composition is 15,16,17, octadecanoid acid ethyl ester, different 17, isostearic acid second
Ester and different methyl margarate.Drug effect differentiates:This product is important blood-activating analgesic." walk and do not keep ".Invigorate blood circulation and the promoting the circulation of qi of simultaneous energy
Open strongly fragrant, be " gas medicine in blood "." whole body blood vessels can be led to ", " the up head, lower menstruation regulating water, middle relieving stagnation ".Promoting blood circulation and stopping pain and can dispel
Scattered exogenous wind, is longer than and only has a headache especially.Ligusticum wallichii is fried and deoiled, and life is attacked with numbness pain.Face card application:1. antimigraine:With Ligusticum wallichii,The root of Dahurain angelica, processFar WillEach 50g,Borneol7g, grinds altogether, with a little medicine end plug nose of gauze bag, right side headache plug left nose, the right nose of left side headache plug.It is clinical
Using:For anticancerTreatment.Additionally, being additionally operable to treatmentFluChill, dizziness, headache, costalgia of chest,Irregular menstruation, AmenorrheaAbdomen Bitterly、PostpartumStasis of blood, and the disease such as traumatic injury, sore swell and ache curative, arthralgia due to wind-dampness.
Radix Glycyrrhizae, root and root system master contain triterpenoid saponin, wherein main one kind is commonly called as glycyrrhizin, and the chemical combination of class containing flavonol
Thing 4',7-Dihydroxyflavanone, liquiritin etc., also compound containing Coumarins Radix Glycyrrhizae coumarin, glycyol etc., separately gather containing alkaloid, Radix Glycyrrhizae Portugal
The compounds such as sugared GBW.Sweet, mild-natured, returns spleen, stomach, the heart, lung channel, invigorating middle warmer and replenishing QI, relieving spasm to stop pain moistens the lung and relieve the cough, purging intense heat and detonicating,
Coordinating the drug actions of a prescription.Burnout deficiency of food is cured mainly, the thin face of flesh is yellow, palpitation, loose stool of suffering from abdominal pain, four limbs contraction, hysteria, cough and asthma,
Abscess of throat, ulcerative carbuncle pyogenic infections, infant fetal toxin and medicine, food poisoning.Radix Glycyrrhizae has removing toxic substances antibacterial action, and anti AIDS virus are made
With, licorice polysaccharide in vitro to vesicular stomatitis virus, adenovirus II type, herpes simplex virus I type and vaccinia virus are equal
There is obvious inhibiting effect, not only can directly inactivate this several virus, and also have effect to intracellular virus, additionally, sweet
Grass also has Antitussive and Expectorant Effect, with anti-inflammatory, affects digestive system, immune system and cardiovascular system, antitumor and anti-prominent
Change, corticotropin sample, anti-oxidant etc. are acted on.The acute and chronic viral hepatitis of clinical treatment, treatment diabetes, treatment
Gastric and duodenal ulcer etc..The present invention is to the concocting method of Radix Glycyrrhizae:Extracting liquorice, except removing LU and impurity, size bar is separate,
Be dipped to 3 four one-tenth it is saturating when, pick up and soften, cut sheet, be dried.
The effect of the present invention:
Cure mainly:Leukaemia, particularly early stage leukaemia, fundamentally improve physical function, and control tumour continues to overgrow and makes it
Final disappearance is gradually reduced, so as to recover healthy.
It is simultaneous to control:The cancer in digestive system such as cancer of the stomach, the cancer of the esophagus, throat cancer, cardiac cancer, pylorus cancer, colorectal cancer.
Our the characteristics of is:
1st, flavour of a drug are moderate, and dosage is moderate, spend moderate, not excessive to waste.
2nd, selected flavour of a drug are all to be proved that for cancer leukaemia particularly can be treated by modern medicine pharmacological evaluation
's.And then always have in existing proved recipe for cancer, folk prescription --- even more than medicine more than half be all not by
Modern medicine pharmacological evaluation proves function for cancer with effect;
3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.Rather than only
It is for cancer, just jump on the bandwagon, as a result it is that " dragon " does not harness the river on the contrary more.
4th, as much as possible " neutralisation ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.This
Sample can just make patient suffer less within the cycle of whole medication, pull the devil by the tail less.And if really occurring " getting angry " or " under let out "
Situation, then can be directed to concrete individual concrete condition completely, a bit " stopping leak ", the medicine of " fall fire " are specifically solved for interim addition
Certainly.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicine sides of being added to
Son, makes patient all take always during very long very long medication, ultimately causes adverse consequences.
The conventional taking dose of the present invention, method are:Above-mentioned decoction three times a day, 1 bottle every time(30ml), administered at empty stomach use;
10 capsules are taken while each taking decoction.Relatively more pungent comparison is eaten during medication sweet etc. to gastrointestinal irritation
Larger food.Medicine efficacy enhancing ingredient is done with pan-fried tomato soup to take, it is better.This medicine three months is a course for the treatment of, typically take two to
Three courses for the treatment of, at most take four courses for the treatment of.
Specific embodiment:By Glabrous Sarcandra Herb 30g, purple mound 10g, edible tulip 5g, Radix Isatidis 15g, subprostrate sophora 30g, bush
15g, Radix Astragali 15g, thunder godvine 3g respectively amplify 10 times, after clean water, are placed in BT-2 stainless steels and extract in kettle, plus 7-9 times oneself
After water, it is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.Extract for second:
Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, plus press through
Filter, filtrate is standby.Third time is extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 points
Clock or so, extraction fluid, pressure filtration, filtrate is standby.Concentration:The extract of three times is merged, B-500 type triple effects are placed in
In vacuum high energy evaporation concentrator, reduce pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into 870-910ml, it is standby.Powder processed:Will
Cordyceps sinensis 10g, Radix Glycyrrhizae 5g respectively amplify 10 times, and it is end together to crush, and cross 100 mesh sieves, standby in being fitted into 0.5g capsules.Packaging:
A. in the concentrate for preparing being fitted into vial or vinyon bottle, every bottle of 30ml, mounted box, vanning, sterilizing (are adopted
60Co irradiation, irradiation dose is 8kGy);B. in capsule being fitted into vial or vinyon bottle, mounted box, vanning, sterilizing (
Using 60Co irradiation, irradiation dose is 8kGy).Warehouse-in:Irradiated finished product is put in storage by the principle of first in first out.
Claims (2)
1. Hui ethnic group's Chinese medicine " Chinese caterpillar fungus leukemia recovery oral liquid " and preparation method thereof, it is by made by the weight proportion of following raw materials according:
Cordyceps sinensis 10g, Glabrous Sarcandra Herb 30g, purple mound 10g, edible tulip 5g,
Radix Isatidis 15g, subprostrate sophora 30g, bush 15g, Radix Astragali 15g,
Thunder godvine 3g, Ligusticum wallichii 5g, Radix Glycyrrhizae 10g
This side is the substantially square of one decoction on the one, in practical application, can also be increased according to the physique of patient and conditions
Theoretical " dialectical compatibility " medicine of the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert ".
2. the raw material weight proportioning of soup processed method of Hui ethnic group's Chinese medicine " Chinese caterpillar fungus leukemia recovery oral liquid " according to claim 1,
It is characterized in that including following preparation processes:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to Cordyceps sinensis, Radix Glycyrrhizae, all amplify 10 times, clean water
Afterwards, BT-2 stainless steels are placed in extract in kettle, plus after 7-9 times of running water, 100 DEG C of constant temperature are heated to and are extracted 1.5-2 hours, separated
Extract, pressure filtration, filtrate is standby;
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature extraction half an hour left
The right side, extraction fluid, pressure filtration, filtrate is standby;
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so,
Extraction fluid, pressure filtration, filtrate is standby;
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg),
80 DEG C are heated to, 870-910ml is concentrated into, it is standby;
(3), powder processed
Cordyceps sinensis 10g, Radix Glycyrrhizae 5g are respectively amplified 10 times, it is end together to crush, and crosses 100 mesh sieves, standby in being fitted into 0.5g capsules
With;
B, packaging
A. in the concentrate for preparing being fitted into vial or vinyon bottle, every bottle of 30ml, mounted box, vanning, sterilizing (are adopted
60Co irradiation, irradiation dose is 8kGy);
B. in capsule being fitted into vial or vinyon bottle, mounted box, vanning, sterilizing (adopt 60Co irradiation, irradiation dose
For 8kGy);
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510749378.6A CN106668525A (en) | 2015-11-08 | 2015-11-08 | Hui-nationality traditional Chinese medicine caterpillar fungus oral solution for treating leukemia and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510749378.6A CN106668525A (en) | 2015-11-08 | 2015-11-08 | Hui-nationality traditional Chinese medicine caterpillar fungus oral solution for treating leukemia and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106668525A true CN106668525A (en) | 2017-05-17 |
Family
ID=58858058
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510749378.6A Withdrawn CN106668525A (en) | 2015-11-08 | 2015-11-08 | Hui-nationality traditional Chinese medicine caterpillar fungus oral solution for treating leukemia and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106668525A (en) |
-
2015
- 2015-11-08 CN CN201510749378.6A patent/CN106668525A/en not_active Withdrawn
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101972338B (en) | Chinese medicinal preparation for treating infantile upper respiratory tract infection and preparation method thereof | |
CN102784363B (en) | Traditional Chinese medicine composition for treating pancreatic cancer and preparation method thereof | |
CN103099959B (en) | Traditional Chinese medicine preparation for treating ulcerative colitis and preparation method thereof | |
CN102078569B (en) | Traditional Chinese medicine preparation for treating liver cancer and preparation method thereof | |
CN103041256B (en) | Chinese herb preparation for curing recurrent respiratory tract infection of children | |
CN103041257B (en) | Chinese materia medica preparation for curing high fever and respiratory tract infection of children | |
CN103041255B (en) | Chinese materia medica preparation for curing swollen sore throat and respiratory tract infection of children | |
CN103007145B (en) | Traditional Chinese medicine composition for treating children rotavirus enteritis and preparation method of composition | |
CN106668409A (en) | Hui traditional Chinese medicine hedyotis diffusa willd anti-esophageal cancer oral liquid and preparation method thereof | |
CN103735906A (en) | Chinese herb preparation for treating dry bronchiectasis and preparation method thereof | |
CN103520337A (en) | Traditional Chinese medicinal composition for treating liver cancer | |
CN103028028B (en) | Traditional Chinese medicine agent for treating primary hepatic carcinoma | |
CN103041258B (en) | Chinese materia medica preparation for curing respiratory tract infection with poor appetite of children | |
CN106668525A (en) | Hui-nationality traditional Chinese medicine caterpillar fungus oral solution for treating leukemia and preparation method thereof | |
CN106668540A (en) | Hui nationality traditional Chinese medicine cordyceps sinensis blood cancer rehabilitation tablet and preparation method thereof | |
CN106668527A (en) | Hui-nationality traditional Chinese medicine caterpillar fungus pills for treating leukemia and preparation method thereof | |
CN106668536A (en) | Hui-nationality traditional Chinese medicine caterpillar fungus granules for treating leukemia and preparation method thereof | |
CN106668699A (en) | Rhizoma zedoariae and herba sarcandrae leukemia-rehabilitating oral liquid as traditional Chinese medicine of Hui nationality and preparation method of rhizoma zedoariae and herba sarcandrae leukemia-rehabilitating oral liquid | |
CN106668734A (en) | Hui nationality traditional Chinese medicine rhizoma curcumae and herba sarcandrae leukemia rehabilitation pill and preparation method thereof | |
CN103041259B (en) | Chinese materia medica preparation for curing excessive phlegm, cough and respiratory tract infection of children | |
CN106668726A (en) | Hui Nationality traditional Chinese medicinal Rhizoma Curcumae and glabrous sarcandra herb leukemia treatment tablet and preparation method thereof | |
CN106668746A (en) | Hui-nationality traditional Chinese medicine rhizoma curcumae and herba sarcandrae granules for treating leukemia and preparation method thereof | |
CN114869987A (en) | A Chinese medicinal composition for preventing and treating hepatocarcinoma | |
CN107823424A (en) | A kind of Chinese medicine composition for treating chronic pharyngitis and preparation method thereof | |
CN106668531A (en) | Hui nationality traditional Chinese medicine six ingredients pills for treating leukaemia and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170517 |