CN106668726A - Hui Nationality traditional Chinese medicinal Rhizoma Curcumae and glabrous sarcandra herb leukemia treatment tablet and preparation method thereof - Google Patents

Abstract

The invention concretely relates to a formula and a preparation method of a Hui Nationality traditional Chinese medicinal Rhizoma Curcumae and glabrous sarcandra herb leukemia treatment tablet. The tablet is a green high-tech Chinese herbal medicine used for treating leukemia. The tablet is a traditional Chinese medicinal tablet prepared through the following steps: mixing of Rhizoma Curcumae, glabrous sarcandra herb, isatis root, Tylophora floribunda Miquel, pawpaw and other Chinese herbal medicines according to a certain ratio, water adding, decoction, extraction, concentration and tabletting. The tablet is mainly used for treating the leukemia, and also is used for treating throat cancer, stomach cancer, colorectal cancer and other digestive system cancers. The tablet has the characteristics of small medicine variety quantity and moderate dosage, and all the medicines are proved by modern medical science pharmacological experiments to be suitable for treating the cancers. The tablet fundamentally improves the body functions, prevents condition exacerbation and recovers the health of bodies at a low cost.

Description

White blood health piece of Hui ethnic group's Chinese medicine art wind and preparation method thereof

Technical field

Hui ethnic group's Chinese medicine " the white blood health piece of art wind " according to the present invention is a kind of leukemic green high-tech Chinese herbal medicine of prevention and treatment.The invention further relates to the preparation method of the medicine, belongs to traditional Chinese medicine class.

Background technology

According to《China's tumour registration annual report in 2014》Data display, according to China for each person 74 years old life-span calculate, Chinese all one's life suffer from malignant tumour probability be 22%, average minute clock has 6 people to be diagnosed as malignant tumour, and tumour has become a kind of common disease in China.At present the cancer patient of China is about ten thousand people more than 800, and every year with the speed of more than 100 ten thousand people in increase（Also have data to show every year is being increased with the speed of 3,120,000 people）.And the whole world

According to statistics, in the cancer patient of China nearly 8,000,000, although the leukemic incidence of disease and number of the infected are not also first 10, the 5/100000 of population is accounted for per annual morbidity, the annual people of about 8-9 ten thousand, but death rate height but as the carninomatosis such as lung cancer, liver cancer, the breast cancer for coming top ten, which results in many patients and loses confidence to living.Leukaemia is constantly bred without limit due to malignant cell clone, and a large amount of proliferative cells have spatially tied up ossis, as a result cause marrow failure and body tissue's organ to be done harm to by leaching, such as acid of the same race because leukaemia can produce some body fluid inhibiting factorsFerritinEtc. (isoferritin) suppress normally to makeHaemocytePropagation, thus just generate clinical a series of sings and symptoms.And most terribly be that while that some people's household economy are not short of money, but due to national all of tumour hospital all the year round overstaffed, thus can get one treatment bed, leukaemic that the regular treatment of some famous expert hospitals --- including over-treatment --- can be enjoyed or relatively little of, addsLeukemic treatmentIt is relatively difficult, many also need to HSCT, Umbilical Cord Blood Transplant,Gene therapyDeng so just more making many leukaemics for still having existence leeway accelerate to have moved towards dead road.

Leukemic pathogenic factor substantially has three, and one is chemical factor, and this reason may not be common, because premise must be some chemicals of patient's Long Term Contact, such as benzene, affirmative is compared in the cause leukaemia effect of benzene.Benzene causes acute leukemia based on acute myeloblastic leukemia and erythroleukemia.Two is inherent cause, and this pathogenic factors is not also proved so far, is have leukaemia family history person to account for percentage eight in leukaemic the reason for clinically why so thinking, so can not ignore the reason for be relatively common.Three is virus, and if patient is in early stage other are suffered fromDiseaseIf, such as some tumours, at this time it is possible to leukaemia, because the homologous gene of most vertebrate is all source tumor gene, this is also one of leukemogenic cause of disease.Although leukemic pathogenic factor clinically also has many disputes, above-mentioned three kinds are relatively common.

It is to carry out regular chemotherapy to regular large hospital to treat leukemic best method at present, and the cure rate of ALL can reach the cure rate of more than 80%, ANLL and also can reach 50%.The incurable chronic myelocytic leukemia patient of those chemotherapy, by Hemopoietic Stem Cell Transplantation, can also also have the healing of 50%-60% possible.But various treatment technologies have its own advantage and a deficiency again, such as HSCT technology, the high-risk or recurrent and refractory leukaemic that can make over to cure obtains and cures chance, but have it is expensive, cause the deficiencies such as rejection；And chemotherapy, chemotherapy not only large side effects, patient suffering is difficult to stand, and needs the time of several years, and success rate is nor 100% ...

Leukaemia is a kind of malignant tumour of general.Traditional Chinese medicine has no leukemic name of disease, but with regard to categories such as category " blood trouble ", " deficiency of blood ", " consumptive disease ", " evil cores " more than its clinical manifestation.Leukaemia is at present more refractory disease more, but refractory representative cannot be controlled, and in addition to above-mentioned western medical treatment method, the traditional Chinese medical science also has many effectively treatment methods.Existing clinical proof Chinese medicine relaxes to this sick curative effect to be stablized, and can reduce the toxic and side effect of chemotherapy, does not produce resistance, and leukemic each phase can be applied.The traditional Chinese medical science, according to the whole body feature diagnosis and treatment of patient, goes for various each phase cancer with organic conception.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effect is slight, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band knurl, and patient is easy to receive and expense is than less expensive.At present doctor trained in Western medicine is also considered as traditional Chinese medicine can contribute to reducing the toxicity of Radiotherapy chemotherapy as the auxiliary treatment of cancer, improve cancer related symptoms, improve life quality, extend life cycle.But exist problem be the traditional Chinese medical science prescription uniformity it is poor, treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always there is --- majority is more than more than half --- medicine to be all not prove " compatibility " medicine of function for cancer and effect " diagnosis and treatment based on an overall analysis of the illness and the patient's condition " by modern medicine pharmacological evaluation in selected Chinese herbal medicine medicinal material, inventors believe that very improper；And folk prescription, folk prescription cure the disease lean on be test, often stop over the time cured the disease.

The content of the invention

The purpose of the present invention, be aiming at Chinese leukaemic it is medical be difficult to and the traditional Chinese medical science see a doctor it is normative it is poor, it is repeatable it is poor, lack high level evidence-based medicine EBM theory and evidence, thus the situation for waiting deficiency by rule of thumb that is mainly for cancer, propose a kind of new dosage and preparation method, there is provided a kind of from the beginning of prevention, reduce the leukemic incidence of disease, start to slow down its tempo induction its apoptosis of induction from canceration or differentiation reverts to the green high-tech Chinese herbal medicine of normal cell, with very low cost, fundamentally improve physical function, so as to get well.Its sharpest edges are to greatest extent to induce self apoptosis of cancer cell and differentiation, promote it progressively to recover normal condition.In specific formula, also coordinate diagnosis and treatment based on an overall analysis of the illness and the patient's condition, according to leukemic origin cause of formation system " blood trouble ", " deficiency of blood ", " consumptive disease ", the features such as " evil core ", according to the concrete condition of patient, different formulas are respectively adopted, with the method for strengthening vital QI to eliminate pathogenic factors adopting both clearing heat method and tonification method, or boosting qi and nourishing yin, strong spleen and liver, or enriching kidney essence, strengthening spleen, tonifying kidney, or it is clearing heat and detoxicating, it is promoting blood circulation and removing blood stasis, or strengthening the spleen and stomach, strongly invigorating QI and blood ... is accomplished not hindering just clearly, benefit does not stay heresy, there is benefit in clear, giving consideration to both the incidental and fundamental, complement each other, a good internal environment is created to hemopoietic system, to accelerate the recovery of hematopoiesis function, it is empty in healthy tendency to correct, the solidifying poison of heresy is poly- and internal organs imbalance of yin and yang function reduces the deficiency that disequilibrium causes immunologic hypofunction, adjust and improve the immunologic function of body, to reachAdopting both clearing heat method and tonification methodThe purpose of overall suppression disease, so as to improve the overall curative effect and late result of leukemia treating, a kind of green high-tech Chinese herbal medicine formula and compound method that function for cancer and effect are proved by modern medicine pharmacological evaluation is provided for leukaemic, with very low or relatively low cost, fundamentally improve physical function, the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, and finally recovers healthy.Thus also to patient one select different treatment methods or several method to share particularly traditional Chinese and western medicine to combine the leeway of complex treatment application to consider according to the personal state of an illness, economic situation, personal inclination, to obtaining optimum curative effect, survival rate is easily improved --- particularly more than 5 years survival rates.

Technical scheme proposed by the invention is：

First, leukemic Hui ethnic group's Chinese medicine of described prevention and treatment " the white blood health piece of art wind " and preparation method thereof, is by made by the weight proportion of following raw materials according：

Curcuma zedoary 30g, Glabrous Sarcandra Herb 30g, Radix Isatidis 15g, Ligusticum wallichii 9g,

Bush 10g, radix tylophorae 5g, pawpaw 15g, camplotheca acuminata 5g,

Indigo naturalis 1.5g, Radix Glycyrrhizae 9g, oldenlandia diffusa 30g,

This side is substantially square for one decoction on the one.In practical application, also the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " theory can be increased according to the physique of patient and conditions“Dialectical compatibility " medicine.

In view of with this, basic side's decoction decoction of medicinal ingredients amount is big, taste is not good enough, patient is difficult to drink, therefore must be prepared using special process.

2nd, it is by the preparation method that above-mentioned each raw material makes Chinese medicinal tablet of the present invention：

A, extract preparation

（1）, extract

A, for the first time extraction：By the weight of said herbal medicine in addition to indigo naturalis, Radix Glycyrrhizae, all amplify 10 times, after clean water, be placed in BT-2 stainless steels and extract in kettle, plus after 7-9 times of running water, be heated to 100 DEG C of constant temperature and extract 1.5-2 hours, extraction fluid, pressure filtration, filtrate is standby.

B, second extraction：Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.

C, third time are extracted：Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.

（2）, concentration

The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10～1.20, it is standby.

（3）, powder processed

Indigo naturalis 1.5g, Radix Glycyrrhizae 9g are respectively amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby.

（4）, dispensing

In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and proper honey water and is sufficiently mixed, stir.

(5) drying, crushing

The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.

(6) granulate

The spice being well mixed is inserted in comminutor and is granulated.

(7) whole grain

The particle for making is carried out into whole grain, 35 mesh sieves are crossed.

(8) it is dried

Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture ＜ 8% at 80 DEG C.

(9) compressing tablet

Add magnesium stearate to be well mixed dry mixed gained medicine and be placed in compressing tablet in tablet press machine（Also can coating）, every 0.5g.

B, packaging

In first the tablet for pressing being fitted into vial or vinyon bottle, then the bottle mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy）.

, warehouse-in

Irradiated finished product is put in storage by the principle of first in first out.

Routine instructions of taking of the invention：Three times a day, 10 tablets once for above-mentioned tablet, and administered at empty stomach is with (taking half an hour after can not drink water in a large number, in order to avoid water down liquid).The pungent grade food larger to gastrointestinal irritation is not eaten during medication.

If this medicine does medicine efficacy enhancing ingredient and takes with pan-fried tomato soup, better.The specific practice of pan-fried tomato soup is：Take from so well-done little tomato（50 grams or so）Chopping, puts 10 grams or so vegetable oil in pot, heat, and is put into appropriate chopped spring onion, salt, pours into be decocted in pot by the tomato of chopping when chopped spring onion blows out fragrance and fries 1-2 minutes, then infuses to be got away into suitable quantity of water and take the dish out of the pot.

The effect of each raw material of the present invention：

Curcuma zedoary,Nature and flavorEffect：It is bitter, pungent, it is warm in nature.Promoting the circulation of qi blood-breaking, Xiao Ji Zhi Tong.It is clinicalUsing：It is mainly used in sonCervical carcinoma, apply also for other various tumours such as liver cancer,Cancer of the stomach, cancer of pancreas,Oophoroma, colon cancer, lung cancer,SkinCancer, leukaemia, spermatogonium cancer, lip cancer, carcinoma of vulva etc..Additionally, this product is additionally operable to treatment, and a lump in the abdomen causing distension and pain, gastral cavity abdomenDistending pain, dyspepsia distending pain, AmenorrheaStomachacheDeng.

Glabrous Sarcandra Herb,Nature and flavorEffect：Taste is pungent, it is mild-natured.It is clearing heat and detoxicating, dispelling wind and eliminating dampness, promoting blood circulation and stopping pain.It is clinicalUsing：Suitable for kinds of tumors, such as the cancer of the esophagus,Cancer of the stomach, colon and rectum carcinoma, cancer of pancreas, liver cancer, acute leukemia etc..

Radix Isatidis,Radix Isatidis is bitter, trembles with fear.The thoughts of returning home, stomach.Effect is clearing heat and detoxicating, cool blood, profit pharynx.Its chemical composition is：Woaded blue root containing indigo, indigo red, cupreol,PalmAcid, uridine, hypoxanthine, uracil,Indigo naturalisKetone and daucosterol etc..Its pharmacological action is：This product has inhibitory action to various gram-positive bacterias, Gram-negative bacteria and influenza virus, arboviruse, parotid gland virus.Improving immunocompetence；There is obvious antipyretic response.Indigo red contained by this product has significant leukemia resisting action；Banlangen Polysaccharide can reduce the content of animal used as test serum cholesterol and triglycerides, and reduce MDA contents, so as to prove this product Wheat Protein.

Ligusticum wallichii,Nature and flavorEffect：Taste is pungent, slight bitter, property intestines trail temperature.Blood-activating and qi-promoting, wind-expelling pain-stopping.Chemical composition：Containing phenolic substances such as alkaloid, forulic acids, also, chuanxingol, Diligustilide, ligustrazine, trimethylamine hydrochloride, choline hydrochloride etc..Additionally, Rhizome of Ligusticum Sinense Oliv. Cv. Chuanxiong still contain neutral oil, its composition be 15,16,17, octadecanoid acid ethyl ester, different 17, isooctadecane acetoacetic ester and different methyl margarate.Drug effect differentiates：This product is important blood-activating analgesic." walk and do not keep ".Invigorate blood circulation and simultaneous energy promote breath and open depression, be " gas medicine in blood "." whole body blood vessels can be led to ", " the up head, lower menstruation regulating water, middle relieving stagnation ".Promoting blood circulation and stopping pain and the scattered exogenous wind that can dispel, are longer than and only have a headache especially.Ligusticum wallichii is fried and deoiled, and life is attacked with numbness pain.Face card application：1. antimigraine：With Ligusticum wallichii,The root of Dahurain angelica, processPolygala rootEach 50g,Borneol7g, grinds altogether, with a little medicine end plug nose of gauze bag, right side headache plug left nose, the right nose of left side headache plug.It is clinicalUsing：For anticancerTreatment.Additionally, being additionally operable to treatmentFluChill, dizziness, headache, costalgia of chest,Irregular menstruation, AmenorrheaStomachache、PostpartumStasis of blood, and the disease such as traumatic injury, sore swell and ache curative, arthralgia due to wind-dampness.

Bush,Nature and flavorEffect：It is sweet, salty, mild-natured.Promoting circulation of blood broken stasis of blood, swelling and pain relieving.It is clinicalUsing：This product closely be used for alimentary canal arsine knurl andCervical carcinoma、Oophoroma, liver cancer and chronic myelogenous leukemia.Additionally, being additionally operable toTreatmentAmenorrheaStomachache、PostpartumHemostasis, suffer from abdominal pain uncomfortable in chest, traumatic injury, knife wound bleeding, icteric hepatitis, La diseases, orchitis,Anaemia, afterpains.Furuncle pain, urinary tract infections, renal shutdownPain in the back, chronic enteritis, enterorrhagia, haematemesis etc..

Radix tylophorae,Nature and flavorEffect：Root：It is bitter, pungent, it is warm in nature, it is poisonous.Dispelling wind and eliminating dampness, blood stasis removing analgesic, relieving cough and relieving asthma antidotes against snake bite.

It is clinicalUsing：Applicable various hematological system tumors, such as leukaemia, lymthoma, lymphosarcoma, also try out in other tumours.

Pawpaw,Pawpaw has liver protection, and antibacterial is antitumor to wait effect.Arthralgia due to wind-dampness, vague aching of limbs, muscle arteries and veins contraction, convulsion of vomiting and diarrhoea, tinea pedis oedema can be controlled.Pawpaw has the reasonable effect of stimulating the circulation of the blood and cause the muscles and joints to relax, and can dry except numbness, is the stupid numbness of long wind, the key medicine of spasm of muscles and vessels.Pawpaw can dehumidify with, stimulate the circulation of the blood and cause the muscles and joints to relax with slow contraction urgency, except vomiting and diarrhoea.Pawpaw includes a kind of ferment, claims pawpaw element, and energy digesting protein can be sharp to absorb with aid digestion, favourable with dyspeptic people to indigestion.It is believed that the pawpaw effect of stimulating the secretion of milk, puerpera can use.Chinese flowering quince juice is wiped on ulcerous skin, ulcer surface healing acceleration can be made.Pawpaw plays the role of to relax gastrointestinal smooth muscle and limb muscle spasm, has significant therapeutic effect to systremma.Papain is used to drive away tapeworm, roundworm and whipworm etc. effectively.Pawpaw contains benzyl isothiocyanate, is broad-spectrum antibiotic, and to saccharomycete, 20 kinds of fungies and tens of kinds of other bacterial strains have effect.Papain reduces can tumor tissues.Pawpaw is kind to control inflexible spasm, is amusing in adjusting with stomach.Cydonic acid adstringency tepor, rheumatism of stimulating the circulation of the blood and cause the muscles and joints to relax numbness.Choleraic myospasm and vomiting and diarrhoea, run quickly globefish tinea pedis has effect.

Camplotheca acuminata,Nature and flavorEffect：It is bitter, puckery, it is cold in nature, it is poisonous.Anticancer, dissipating bind, heat-clearing desinsection.It is clinicalUsing：Suitable for kinds of tumors, such as the cancer of the esophagus,Cancer of the stomach, the carcinoma of the rectum, liver cancer, carcinoma of urinary bladder, adenocarcinoma ovaries, chronic granulocytic leukemia, acute lymphatic leukemia, lymphosarcoma etc..

Indigo naturalis, meridian distribution of property and flavor：It is salty, tremble with fear.Return liver, lung channel.Effect：It is clearing heat and detoxicating, blood cooling and ecchymoses removing, clearing liver-fire, arresting convulsion.Pharmacological action：This product has antitumaous effect, its active ingredient indigo red has the inhibitory action of moderate strength to animal transplanting tumor.There is antibacterial action to staphylococcus aureus, bacillus anthracis, Shigella shigae, comma bacillus.It is indigo still to have certain hepatoprotective effect.Clinical research：It is reported that, indigo naturalis can be used for various diseases, such as：Acute pelvitis of pelvic cavity, Cardiac and esophageal carcinoma obstruction, acute icteric hepatitis, CAH, additionally, indigo naturalis still treats indirect bilirubin increases disease, chronic granulocyteLeukaemia, epilepsy, nasal vestibulitis, hemorrhage of digestive tract, bedsore, orchitis, eczema of anus and senile vahinitis etc..

Radix Glycyrrhizae,Root and root system master contain triterpenoid saponin, wherein main one kind is commonly called as glycyrrhizin, and the 4',7-Dihydroxyflavanone of chlorins compound containing flavones, liquiritin etc., the also Radix Glycyrrhizae of compound containing Coumarins coumarin, glycyol etc., separately containing compounds such as alkaloid, Radix Glycyrrhizae glucan GBW.Sweet, mild-natured, returns spleen, stomach, the heart, lung channel, invigorating middle warmer and replenishing QI, relieving spasm to stop pain moistens the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription.Burnout deficiency of food is cured mainly, the thin face of flesh is yellow, palpitation, suffer from abdominal pain loose stool, four limbs contraction, hysteria, cough and asthma, abscess of throat, ulcerative carbuncle pyogenic infections, infant fetal toxin and medicine, food poisoning.Radix Glycyrrhizae has removing toxic substances antibacterial action, anti-AIDS toxic action, licorice polysaccharide has obvious inhibiting effect to vesicular stomatitis virus, adenovirus II type, herpes simplex virus I type and vaccinia virus in vitro, not only can directly inactivate this several virus, and also have effect to intracellular virus, additionally, Radix Glycyrrhizae also has Antitussive and Expectorant Effect, with anti-inflammatory, affect digestive system, immune system and cardiovascular system, the effect such as antitumor and anti-mutation, corticotropin sample, anti-oxidant.The acute and chronic viral hepatitis of clinical treatment, treatment diabetes, treatment gastric and duodenal ulcer etc..The present invention is to the concocting method of Radix Glycyrrhizae：Extracting liquorice, except removing LU and impurity, size bar is separate, be dipped to 3 four one-tenth it is saturating when, pick up and soften, cut sheet, be dried.

Long-noded pit viper house grass：Effect:It is clearing heat and detoxicating, diuresis of blood circulation promoting, Xiaofeng San gas, removing toxic substances detumescence, pain relieving.Cure mainly：Lung heat, intestines heat, heat accumulating in the large intestine, laryngalgia, sore swells, snake sore, all enterodynia, appendicitis, tonsillitis, sphagitis, urinary tract infections, pelvic infecton, appendicitis, hepatitis, bacillary dysentery, venomous snake bite, tumour.Also can be used for alimentary tract cancer.Modern pharmacology research proves that Hedyotidis Diffusae can strengthen the immunity of body, suppresses the growth of tumour cell, has inhibitory action to pathogenic bacteria such as Pseudomonas aeruginosa, staphylococcus aureus, pneumococcus, shigella dysenteriaes, is in fact the good medicine of " clearing heat and detoxicating ".

The effect of the present invention：

Cure mainly：Leukaemia, particularly early stage leukaemia, fundamentally improve physical function, and control tumour continues to overgrow and makes it that final disappearance is gradually reduced, so as to recover healthy.

It is simultaneous to control：The cancer in digestive system such as cancer of the stomach, the cancer of the esophagus, throat cancer, cardiac cancer, pylorus cancer, colorectal cancer.

Our the characteristics of is：

1st, flavour of a drug are moderate, and dosage is moderate, spend relatively low, do not waste.

2nd, selected flavour of a drug are all to be proved for cancer particularly can to treat leukemic by modern medicine pharmacological evaluation.And then always have in existing proved recipe for cancer, folk prescription --- even more than medicine more than half be all not by modern medicine pharmacological evaluation proved function for cancer and effect.

3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.As long as rather than it is for cancer, just jump on the bandwagon, be as a result that " dragon " does not harness the river on the contrary more.

4th, as much as possible " neutralisation ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.Patient can be thus set to suffer less within the cycle of whole medication, pull the devil by the tail less.And if really there is the situation of " getting angry " or " under let out ", then can be directed to concrete individual concrete condition completely, a bit " stopping leak ", the medicine of " fall fire " are specifically solved for interim addition.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicines are added to prescription, patient is all taken always during very long very long medication, ultimately cause adverse consequences.

The conventional taking dose of the present invention, method are：Three times a day, 10 tablets once, and administered at empty stomach is used；The foods larger to gastrointestinal irritation such as relatively more pungent comparison is sweet are eaten during medication.Medicine efficacy enhancing ingredient is done with pan-fried tomato soup to take, it is better.This medicine is a course for the treatment of in three months, typically takes two to three courses for the treatment of, at most takes four courses for the treatment of.

Specific embodiment：Curcuma zedoary 30g, Glabrous Sarcandra Herb 30g, Radix Isatidis 15g, Ligusticum wallichii 9g, bush 10g, radix tylophorae 5g, pawpaw 15g, camplotheca acuminata 5g, oldenlandia diffusa 30g are respectively amplified into 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, it is heated to 100 DEG C of constant temperature to extract 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.Extract for second：Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.Third time is extracted：Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.Concentration：The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10～1.20, it is standby.Powder processed：Indigo naturalis 1.5g, Radix Glycyrrhizae 9g are respectively amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby.Dispensing：In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and proper honey water and is sufficiently mixed, stir.Drying, crushing：The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.Granulation：The spice being well mixed is inserted in comminutor and is granulated.Whole grain：The particle for making is carried out into whole grain, 35 mesh sieves are crossed.It is dried：Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture ＜ 8% at 80 DEG C.Compressing tablet：Add magnesium stearate to be well mixed dry mixed gained medicine and be placed in compressing tablet in tablet press machine（Also can coating）, every 0.5g.Packaging：In first the tablet for pressing being fitted into vial or vinyon bottle, then the bottle mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy）.Warehouse-in：Irradiated finished product is put in storage by the principle of first in first out.

Claims (2)

1. white blood health piece of Hui ethnic group's Chinese medicine art wind and preparation method thereof, is by made by the weight proportion of following raw materials according：

Curcuma zedoary 30g, Glabrous Sarcandra Herb 30g, Radix Isatidis 15g, Ligusticum wallichii 9g,

Bush 10g, radix tylophorae 5g, pawpaw 15g, camplotheca acuminata 5g,

Indigo naturalis 1.5g, Radix Glycyrrhizae 9g, oldenlandia diffusa 30g

This side is the substantially square of one decoction on the one, in practical application, can also increase the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " theory according to the physique of patient and conditions“Dialectical compatibility " medicine.

2. the weight proportion of the white blood health piece of Hui ethnic group's Chinese medicine art wind according to claim 1, it is characterised in that including following preparation processes：

A, extract preparation

（1）, extract

A, for the first time extraction：By the weight of said herbal medicine in addition to indigo naturalis, Radix Glycyrrhizae, all amplify 10 times, after clean water, be placed in BT-2 stainless steels and extract in kettle, plus after 7-9 times of running water, be heated to 100 DEG C of constant temperature and extract 1.5-2 hours, extraction fluid, pressure filtration, filtrate is standby；

B, second extraction：Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby；

C, third time are extracted：Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby；

（2）, concentration

The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10～1.20, it is standby；

（3）, powder processed

Indigo naturalis 1.5g, Radix Glycyrrhizae 9g are respectively amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby；

（4）, dispensing

In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and proper honey water and is sufficiently mixed, stir；

(5) drying, crushing

The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves；

(6) granulate

The spice being well mixed is inserted in comminutor and is granulated；

(7) whole grain

The particle for making is carried out into whole grain, 35 mesh sieves are crossed；

(8) it is dried

Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture ＜ 8% at 80 DEG C；

(9) compressing tablet

Add magnesium stearate to be well mixed dry mixed gained medicine and be placed in compressing tablet in tablet press machine（Also can coating）, every 0.5g；

B, packaging

In first the tablet for pressing being fitted into vial or vinyon bottle, then the bottle mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy）；

C, warehouse-in

Irradiated finished product is put in storage by the principle of first in first out.