CN103100047A - Traditional Chinese medicine composition for treating gastric cancer and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating gastric cancer and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating gastric cancer, in particular to a traditional Chinese medicine composition for treating gastric cancer and a preparation method thereof. The traditional Chinese medicine composition comprises pseudo-ginseng, bittersweet herb, hairyvein agrimonia herb and bud, Indian iphigenia bulb, pinellia tuber, spreading hedyotis herb, barbed skullcap herb, cochinchnese asparagus root, dwarf lilyturf tuber, flos sophorae, vietnamese sophora root, rhizoma corydalis, largehead atractylodes rhizome, turmeric and onions. The traditional Chinese medicine composition is effective in treatment of gastric cancer, and not only has the effects of relieving pain and stopping bleeding, but also is anticancer and antitumor. The traditional Chinese medicine composition for treating gastric cancer usually employs local common medicinal materials, so that the cost is low, and the economical burden of a patient is reduced.
Description
Technical field
The invention discloses a kind of gastric cancer Chinese medicine composition for the treatment of, especially treat Chinese medicine composition of gastric cancer and preparation method thereof.Genus Chinese medicine field.
Background technology
Gastric cancer is one of cancer that in worldwide, sickness rate is the highest.Annual newly-increased 900,000 patients with gastric cancer in the whole world have 700,000 people to die from gastric cancer simultaneously every year.The sickness rate of gastric cancer significantly raises along with the increase at age, and the peak age of morbidity was at 50 years old～80 years old.Wherein, male's sickness rate is 1.5～2.5 times of women, occupies second and mortality rate is only second to pulmonary carcinoma.Simultaneously, women's incidence gastric cancer rate and mortality rate trend that rising is arranged.China is the district occurred frequently of gastric cancer, gastric cancer year prevalence and mortality rate are all more than 2 times of world average level.Show according to the Second National coroner's inquest result of sanitation Ministry tissue, the mortality rate of Chinese gastric cancer accounts for all because of 23.2% of cancer mortality number, near 1/4th.
The symptom of gastric cancer:
1. the above non-evident sympton of early gastric cancer 70%, development along with the state of an illness, can engender nonspecific, as to exactly like gastritis or gastric ulcer symptom, comprise the glutted discomfort of epigastrium or dull pain, pantothenic acid, belch, feel sick, vomiting, loss of appetite, melena etc. are occasionally arranged.
2. the advanced gastric carcinoma symptom is seen gastric area pain, often is gnawing property, without obvious relation, similar peptic ulcer pain is arranged also with feed, can alleviate after feed.
Epigastrium feeling of repletion, sense of heaviness, anorexia, stomachache, nausea,vomiting,diarrhea, become thin, anemia, edema, heating etc.The carcinoma of gastric cardia main manifestations is uncomfortable under xiphoid-process, pain or retrosternal pain, companion's dysphagia sense or dysphagia; At the bottom of stomach and the normal non-evident sympton of cardia inferior segment cancer, just arouse attention when the diabrosis that necroses causes upper gastrointestinal hemorrhage until tumor is huge, or cause and begin to give attention after dysphagia because of the tumor-infiltrated cardia that extends to; The body of stomach cancer is more common with intumescent, and the uncomfortable appearance of pain is more late; The gastric antrum lesser curvature side is the most common with ulcer type cancer, thus the symptom of epigastrium pain occur early, when tumor prolong and during pyloric ostium, can cause nausea, the pyloric obstruction symptom such as vomiting.The cancerous protuberance diffusion transfer can cause the transfer of ascites, hepatomegaly, jaundice and lung, brain, the heart, prostate, ovary, bone marrow etc. and corresponding symptom occur.
For the treatment of gastric cancer, doctor trained in Western medicine adopts operative treatment, radiotherapy or chemotherapy three one usually now, or the method for together treating.Operative treatment: generally include radical surgery, palliative operation, the operation of detecting property.Namely take operation as the means complete removal of lesions was or the cut-out focus, reach the method for curing or controlling cancer.Radiotherapy: being called for short radiotherapy, is to utilize the high-energy electromagnetic radiation line to act on life entity, and biomolecular structure is changed, and reaches a kind of Therapeutic Method of destruction of cancer cells purpose.It is because cancerous cell is responsive to lonizing radiation that radiation can be treated cancer.The lonizing radiation of using clinically at present have x-ray treatment and r line to treat two kinds.Chemotherapy: chemotherapy is to take the medicine intravascular to whole body, and is all influential to the health all cells.This therapy is sometimes also referred to as " born of the same parents poison therapy ", because medicine used all is harmful to, or even with toxicity, and cells in vivo, whether no matter malignant cell, all be damaged.
No matter be adopt operative treatment, radiotherapy or adopt chemotherapy, all patient's health caused great burden, and costly, sufferer is born painful large.
Summary of the invention
Development along with Chinese Chinese medicine, on treatment and control gastric cancer, people have recognized that gradually treatment by Chinese herbs gastric cancer disease therapeutic process has no side effect, the patient bears painful little, and the advantage that cost is saved relatively is for the present situation of existing western medical treatment cancer, one of purpose of the present invention is to provide a kind of Chinese medicine composition for the treatment of cancer, have characteristics easy to operate, evident in efficacy, and its adopts comparatively common in the localities Chinese crude drug as raw material, with low cost.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of Chinese medicine composition for the treatment of gastric cancer takes off the primary raw material of stating weight proportion and is prepared from: Radix Notoginseng 3-9 part, Herba Solani Lyrati 15-30 part, Herba Agrimoniae 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 3-9 part, Rhizoma Pinelliae 3-10 part, Herba Hedyotidis Diffusae 15-30 part (preferred, Herba Hedyotidis Diffusae 15.5-29.5 part), Herba Scutellariae Barbatae 15-30 part, Radix Asparagi 10-20 part, Radix Ophiopogonis 10-20 part, Flos Sophorae 5-9 part, Radix Sophorae Tonkinensis 3-6 part, Rhizoma Corydalis 3-15 part, Rhizoma Atractylodis Macrocephalae 15-40 part, Rhizoma Curcumae Longae 10-30 part, Bulbus Allii Cepae 10-30 part.
A kind of Chinese medicine composition for the treatment of gastric cancer, preferred scheme is taken off the primary raw material of stating weight proportion and is prepared from: Radix Notoginseng 5-9 part, Herba Solani Lyrati 16-25 part, Herba Agrimoniae 15-25 part, Pseudobulbus Cremastrae Seu Pleiones 4-8 part, Rhizoma Pinelliae 4-8 part, Herba Hedyotidis Diffusae 18-28 part, Herba Scutellariae Barbatae 18-25 part, Radix Asparagi 12-18 part, Radix Ophiopogonis 14-18 part, Flos Sophorae 6-8 part, Radix Sophorae Tonkinensis 3.5-5 part, Rhizoma Corydalis 6-14 part, Rhizoma Atractylodis Macrocephalae 20-38 part, Rhizoma Curcumae Longae 15-28 part, Bulbus Allii Cepae 12-28 part.
A kind of Chinese medicine composition for the treatment of gastric cancer, best scheme is taken off the primary raw material of stating weight proportion and is prepared from: 8 parts of Radix Notoginseng, 20 parts of Herba Solani Lyratis, 20 parts of Herba Agrimoniaes, 6 parts of Pseudobulbus Cremastrae Seu Pleioness, 5 parts of the Rhizoma Pinelliaes, 20 parts of Herba Hedyotidis Diffusaes, 20 parts of Herba Scutellariae Barbataes, 15 parts of Radix Asparagis, 15 parts of Radix Ophiopogonis, 7 parts, Flos Sophorae, 4 parts of Radix Sophorae Tonkinensiss, 12 parts of Rhizoma Corydalis, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts, Rhizoma Curcumae Longae, 15 parts of Bulbus Allii Cepaes.
Another object of the present invention just is to provide the preparation method of above-mentioned treatment gastric cancer.
A kind of preparation method for the treatment of the Chinese medicine composition of gastric cancer mainly is prepared from by following step:
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, Bulbus Allii Cepae are smashed and be soaked in water 20-60 minute, boiled with high heat, change slow fire and add thermal distillation or pass into vapor distillation 30-120 minute, volatile oil and water are together distilled, collect distillate, standing 20-50 minute, distillate was cooled to 20-30 ℃, after get upper strata fluid, fluid is heated to 100 ℃-200 ℃, keep sterilization in 2-8 minute, be cooled to room temperature, after to be distributed into air-tight bottle standby.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Rhizoma Pinelliae intense fire are fried open, turn 10-20 at a simmer minute, then putting into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Radix Ophiopogonis, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis changes intense fire and is fried open, rear slow fire is continuous to be fried in shallow oil 20-40 minute, leach medicinal liquid, be a pair, once a day.
A kind of preparation method for the treatment of the Chinese medicine composition of gastric cancer, preferred, mainly be prepared from by following step:
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, Bulbus Allii Cepae are smashed and be soaked in water 30-50 minute, boiled with high heat, change slow fire and add thermal distillation or pass into vapor distillation 40-80 minute, volatile oil and water are together distilled, collect distillate, standing 25-40 minute, distillate was cooled to 25-28 ℃, after get upper strata fluid, fluid is heated to 120-180 ℃, keep sterilization in 3-6 minute, be cooled to room temperature, after to be distributed into air-tight bottle standby.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Rhizoma Pinelliae intense fire are fried open, turn 12-18 at a simmer minute, then putting into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Radix Ophiopogonis, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis changes intense fire and is fried open, rear slow fire is continuous to be fried in shallow oil 25-35 minute, leach medicinal liquid, be a pair, once a day.
A kind of preparation method for the treatment of the Chinese medicine composition of gastric cancer, best, mainly be prepared from by following step:
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, Bulbus Allii Cepae are smashed and be soaked in water 35 minutes, boiled with high heat, change slow fire and add thermal distillation or passed into vapor distillation 45 minutes, volatile oil and water are together distilled, collect distillate, standing 30 minutes, distillate was cooled to 26 ℃, after get upper strata fluid, fluid is heated to 150 ℃, keep sterilization in 4 minutes, be cooled to room temperature, after to be distributed into air-tight bottle standby.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Rhizoma Pinelliae intense fire are fried open, turn 15 minutes at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Radix Ophiopogonis, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be fried in shallow oil 30 minutes, leaching medicinal liquid, is a pair, once a day.
This Chinese medicine composition is remarkable to the gastric cancer effect, and the effect of pain relieving, hemostasis is not only arranged, and also has anticancer antineoplastic action.Multiselect of the present invention is with local common medical material, and is cheap, alleviated patient's financial burden.
The pharmacological effect of each crude drug is respectively:
Radix Notoginseng: sweet in the mouth, little hardship, warm in nature.Styptic powder blood is arranged, and antiinflammatory protects the liver, antitumor, and the effect of analgesic therapy is used for having a delicate constitution and all kinds of mass formed by blood stasis patient.
Herba Solani Lyrati: another name Herba Solani Lyrati, Pennisetum centrasiaticum Tzvel, hair Herba Senecionis Scandentis, hair Radix seu Caulis fici Martinii, Solanum lyratum Thunb., hair Xiucai, calabash grass, gold thread mossback.Bitter in the mouth, property is flat, and is slightly poisonous.Removing toxic substances and promoting subsidence of swelling is arranged, and anticancer effect is used for cancer, icterohepatitis.
Herba Agrimoniae: cry again Western Agrimony.Bitter in the mouth, warm in nature.Astringing to arrest bleeding, dysentery relieving, parasite killing.Be widely used in various hemorrhage cards, for example: haematemesis, hematuria, have blood in stool, metrorrhagia, spitting of blood, epistaxis, dysentery, impairment caused by overstrain is taken off power, carbuncle, traumatic injury, the cards such as wound hemorrhage have inhibitory action to cancerous cell, are used for cancer and various hemorrhage disease.
Pseudobulbus Cremastrae Seu Pleiones: sweet in the mouth, cool in nature.Heat-clearing and toxic substances removing is arranged, eliminating stagnation, antineoplastic effect.
The Rhizoma Pinelliae: acrid in the mouth, warm in nature, slightly poisonous.Antitussive is arranged, and tell in the town, anticancer, and the effect of blood pressure lowering is used for cancer, nausea and vomiting.
Herba Hedyotidis Diffusae: bitter in the mouth, cold nature.Another name: Herba Hedyotidis Diffusae, Herba Turczaninowiae Fastigiatae, Radix Picriae felterrae are the dry herb of Maguireothamnus speciosus Herba Hedyotidis Diffusae.Heat reliving and toxin-eliminating is arranged, resolving carbuncle and expulsing boil, detumescence, antitumor, the effect of antiinflammatory is used for the tumors such as acute lymphoblastic type, granulocyte type.
Herba Scutellariae Barbatae: acrid in the mouth, hardship, cold in nature.Heat-clearing and toxic substances removing is arranged, the dissipating blood stasis hemostasis, anticancer effect is used for leukemia, gastric cancer, esophageal carcinoma.
Radix Asparagi: sweet in the mouth, cold in nature, be tonic.Have nourshing Yin and drynsessmoistening prescriptionly, antibiotic, the antineoplastic effect is used for leukemia, the disease of the deficiency of YIN.
Radix Ophiopogonis: sweet in the mouth, cold nature.Reinforcing stomach reg fluid is arranged, hemostasis, hypoglycemic effect is used for diabetes, spitting of blood, the disease of haematemesis.
Flos Sophorae: bitter in the mouth, cold nature.Hemostasis is arranged, pain relieving, antiinflammatory, the antiulcer effect is used for spitting blood, gastroenteritic ulcer etc.
Radix Sophorae Tonkinensis: bitter in the mouth, cold in nature.Detoxifcation is arranged, detumescence, pain relieving, the antineoplastic effect is used for the malignant tumor effect remarkable.
Rhizoma Corydalis: acrid in the mouth, warm in nature.Promoting blood circulation to remove blood stasis is arranged, promoting the circulation of QI pain relieving, the breast side of body, epigastric pain. amenorrhea dysmenorrhea, postpartum stagnation, the effect of tumbling and swelling.
The Rhizoma Atractylodis Macrocephalae: sweet in the mouth, warm in nature.Invigorating the spleen and benefiting QI is arranged, improve resistance against diseases, the antineoplastic effect is used for esophageal carcinoma, deficiency of the spleen causing weakness of QI.
Rhizoma Curcumae Longae: acrid in the mouth, warm in nature.Circulation of qi promoting is arranged, inducing menstruation to relieve menalgia, antitumor, antiinflammatory, the effect of blood fat reducing is used for lymphatic cancer, the twinge of the breast side of body.
Bulbus Allii Cepae: acrid in the mouth, warm in nature.Another name: ball Herba Alii fistulosi, onion, Onion, onion, Dutch Herba Alii fistulosi.Stomach-invigorating intestine-moisturizing is arranged, the cold expelling blood pressure lowering, the effect of prophylaxis of cancer is used for inappetence, three-hypers.
Chinese medicine composition of the present invention is debated the principle of disease treatment based on Chinese medicine.The medical material of selecting is divided into the Orally-administered decoction medicine and external is applied ointment or plaster, and inside and outsidely treats simultaneously, treats more comprehensively, and the affected area administration is rapider, and lasting medicine is taken into account inside and outside belonging to, the gastric cancer prescription for the treatment of both the principal and secondary aspects of a disease.Gastric cancer there is fabulous therapeutical effect, for because of the long-term thin and weak health of chemicotherapy, fabulous opsonic action being arranged.
The specific embodiment
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1A kind of Chinese medicine composition for the treatment of gastric cancer takes off the primary raw material of stating weight proportion and is prepared from Radix Notoginseng 3 grams, Herba Solani Lyrati 15 grams, Herba Agrimoniae 10 grams, Pseudobulbus Cremastrae Seu Pleiones 3 grams, the Rhizoma Pinelliae 3 grams, Herba Hedyotidis Diffusae 15 grams, Herba Scutellariae Barbatae 15 grams, Radix Asparagi 10 grams, Radix Ophiopogonis 10 gram, Flos Sophorae 5 grams, Radix Sophorae Tonkinensis 3 grams, Rhizoma Corydalis 3 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Rhizoma Curcumae Longae 10 grams, Bulbus Allii Cepae 10 grams.
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, Bulbus Allii Cepae are smashed and be soaked in water 20 minutes, boiled with high heat, change slow fire and add thermal distillation or passed into vapor distillation 30 minutes, volatile oil and water are together distilled, collect distillate, standing 20 minutes, distillate was cooled to 20 ℃, after get upper strata fluid, fluid is heated to 100 ℃, keep sterilization in 2 minutes, be cooled to room temperature, after to be distributed into air-tight bottle standby.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Rhizoma Pinelliae intense fire are fried open, turn 10 minutes at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Radix Ophiopogonis, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be fried in shallow oil 20 minutes, leaching medicinal liquid, is a pair, once a day.
Embodiment 2A kind of Chinese medicine composition for the treatment of gastric cancer takes off the primary raw material of stating weight proportion and is prepared from Radix Notoginseng 5 grams, Herba Solani Lyrati 16 grams, Herba Agrimoniae 15 grams, Pseudobulbus Cremastrae Seu Pleiones 4 grams, the Rhizoma Pinelliae 4 grams, Herba Hedyotidis Diffusae 18 grams, Herba Scutellariae Barbatae 18 grams, Radix Asparagi 12 grams, Radix Ophiopogonis 14 gram, Flos Sophorae 6 grams, Radix Sophorae Tonkinensis 3.5 grams, Rhizoma Corydalis 6 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, Rhizoma Curcumae Longae 15 grams, Bulbus Allii Cepae 12 grams.
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, Bulbus Allii Cepae are smashed and be soaked in water 30 minutes, boiled with high heat, change slow fire and add thermal distillation or passed into vapor distillation 40 minutes, volatile oil and water are together distilled, collect distillate, standing 25 minutes, distillate was cooled to 25 ℃, after get upper strata fluid, fluid is heated to 120 ℃, keep sterilization in 3 minutes, be cooled to room temperature, after to be distributed into air-tight bottle standby.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Rhizoma Pinelliae intense fire are fried open, turn 12 minutes at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Radix Ophiopogonis, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be fried in shallow oil 25 minutes, leaching medicinal liquid, is a pair, once a day.
Embodiment 3A kind of Chinese medicine composition for the treatment of gastric cancer takes off the primary raw material of stating weight proportion and is prepared from Radix Notoginseng 9 grams, Herba Solani Lyrati 25 grams, Herba Agrimoniae 25 grams, Pseudobulbus Cremastrae Seu Pleiones 8 grams, the Rhizoma Pinelliae 8 grams, Herba Hedyotidis Diffusae 28 grams, Herba Scutellariae Barbatae 25 grams, Radix Asparagi 18 grams, Radix Ophiopogonis 18 gram, Flos Sophorae 8 grams, Radix Sophorae Tonkinensis 5 grams, Rhizoma Corydalis 14 grams, the Rhizoma Atractylodis Macrocephalae 38 grams, Rhizoma Curcumae Longae 28 grams, Bulbus Allii Cepae 28 grams.
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, Bulbus Allii Cepae are smashed and be soaked in water 50 minutes, boiled with high heat, change slow fire and add thermal distillation or passed into vapor distillation 80 minutes, volatile oil and water are together distilled, collect distillate, standing 40 minutes, distillate was cooled to 28 ℃, after get upper strata fluid, fluid is heated to 180 ℃, keep sterilization in 6 minutes, be cooled to room temperature, after to be distributed into air-tight bottle standby.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Rhizoma Pinelliae intense fire are fried open, turn 18 minutes at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Radix Ophiopogonis, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be fried in shallow oil 35 minutes, leaching medicinal liquid, is a pair, once a day.
Embodiment 4A kind of Chinese medicine composition for the treatment of gastric cancer takes off the primary raw material of stating weight proportion and is prepared from Radix Notoginseng 9 grams, Herba Solani Lyrati 30 grams, Herba Agrimoniae 30 grams, Pseudobulbus Cremastrae Seu Pleiones 9 grams, the Rhizoma Pinelliae 10 grams, Herba Hedyotidis Diffusae 30 grams, Herba Scutellariae Barbatae 30 grams, Radix Asparagi 20 grams, Radix Ophiopogonis 20 gram, Flos Sophorae 9 grams, Radix Sophorae Tonkinensis 6 grams, Rhizoma Corydalis 15 grams, the Rhizoma Atractylodis Macrocephalae 40 grams, Rhizoma Curcumae Longae 30 grams, Bulbus Allii Cepae 30 grams.
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, Bulbus Allii Cepae are smashed and be soaked in water 60 minutes, boiled with high heat, change slow fire and add thermal distillation or passed into vapor distillation 120 minutes, volatile oil and water are together distilled, collect distillate, standing 50 minutes, distillate was cooled to 30 ℃, after get upper strata fluid, fluid is heated to 200 ℃, keep sterilization in 8 minutes, be cooled to room temperature, after to be distributed into air-tight bottle standby.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Rhizoma Pinelliae intense fire are fried open, turn 20 minutes at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Radix Ophiopogonis, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be fried in shallow oil 40 minutes, leaching medicinal liquid, is a pair, once a day.
Embodiment 5A kind of Chinese medicine composition for the treatment of gastric cancer takes off the primary raw material of stating weight proportion and is prepared from Radix Notoginseng 8 grams, Herba Solani Lyrati 20 grams, Herba Agrimoniae 20 grams, Pseudobulbus Cremastrae Seu Pleiones 6 grams, the Rhizoma Pinelliae 5 grams, Herba Hedyotidis Diffusae 20 grams, Herba Scutellariae Barbatae 20 grams, Radix Asparagi 15 grams, Radix Ophiopogonis 15 gram, Flos Sophorae 7 grams, Radix Sophorae Tonkinensis 4 grams, Rhizoma Corydalis 12 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Rhizoma Curcumae Longae 25 grams, Bulbus Allii Cepae 15 grams.
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, Bulbus Allii Cepae are smashed and be soaked in water 35 minutes, boiled with high heat, change slow fire and add thermal distillation or passed into vapor distillation 45 minutes, volatile oil and water are together distilled, collect distillate, standing 30 minutes, distillate was cooled to 26 ℃, after get upper strata fluid, fluid is heated to 150 ℃, keep sterilization in 4 minutes, be cooled to room temperature, after to be distributed into air-tight bottle standby.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Rhizoma Pinelliae intense fire are fried open, turn 15 minutes at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Radix Ophiopogonis, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be fried in shallow oil 30 minutes, leaching medicinal liquid, is a pair, once a day.
For making the present invention reach optimum therapeuticing effect, Chinese medicine decoction of the present invention, once a day, each pair, volatile oil is applied in the body surface at Ashi point (generally all decide with sick at the acupuncture point, and multidigit is around pathological changes), the tsusanli acupoint (two) and position, tumor place, twice of every day.
Model case one
Liu xx, female, 47 years old, Liaocheng of Shandong Province Shenxian County Zhang Lou.Symptom: the regular dull pain of stomach, belch, vomiting do not have appetite, and health is become thin weak.Go to hospital to make a definite diagnosis and be gastric cancer mid-term, did chemotherapy 2 months, stop treatment because standing and hold untoward reaction and high expense that can't stand chemotherapy.Sick age: 1 year.Examine the time: on March 23rd, 2011; Take Chinese medicine decoction of the present invention, once a day, and smear volatile oil in the tsusanli acupoint (two), WEIYU acupoint, Shangwan point, used traditional Chinese medicine composition for treating of the present invention 5 days every day twice, pain symptom alleviates, and appetite is recovered to some extent; Use traditional Chinese medicine composition for treating of the present invention 4 months, and went the not diffusion of hospital's check cancerous cell; Used traditional Chinese medicine composition for treating of the present invention 7 months, tumor cell diminishes, at present rehabilitation.
Model case two
Liu xx, man, 39 years old, Meng Jia village, Jin Zhuan town, Jining City in Shandong Province Sishui County.Symptom: the difficulty of swallowing of eating, weight loss, intermittent stomach pain is with serious vomiting, and removing hospital diagnosis is early gastric cancer.Sick age: 5 months.Examine the time: on July 3rd, 2010; Take Chinese medicine decoction of the present invention, once a day, and smear volatile oil in the tsusanli acupoint (two), diaphragm shu cave, used traditional Chinese medicine composition for treating of the present invention 10 days every day twice, symptoms of emesis alleviates, and pain has very large alleviation; Used traditional Chinese medicine composition for treating of the present invention 3 months, function of deglutition recovers fully, obviously diminishes through the examination in hospital tumor.Used traditional Chinese medicine composition for treating of the present invention 10 months, tumor disappears; Use separately volatile oil to consolidate one month, so far without recurrence.
Model case three
Open xx, female, 48 years old, the Han Zhuan of Pingdu City Lan Di town, Shandong Province Soviet Union.Symptom: just begun to swallow the pain obstinate, with the symptom of serious cough, spat blood afterwards, the obvious enlargement of throat.Be diagnosed as intermediate gastric carcinoma through examination in hospital.Sick age: 6 months.Examine the time: on July 22nd, 2011; Take Chinese medicine decoction of the present invention, once a day, and in (on forearm palmar band 2 cun of Neiguan acupoints, article two, between muscle), (below knee joint approximately 3 cun of the tsusanli acupoints, the about distance of 4 horizontal fingers), ZHONGWAN acupoint (central authorities of xiphoid-process and umbilicus line) massage administration, every day twice, used traditional Chinese medicine composition for treating of the present invention 10 days, the spitting of blood sx↓, pharyngeal pain is alleviated to some extent; Used traditional Chinese medicine composition for treating of the present invention 2 months, laryngeal neoplasm dwindles; Use traditional Chinese medicine composition for treating of the present invention 5 months, and found atrophy of tumor after hospital's check, in continuing at present to take.
Model case four
Liu xx, man, 55 years old, the Jining City in Shandong Province Tang Cun of Zoucheng City.Symptom: on November 29th, 2010 is medical because of hepatic region severe pain, checks and finds that liver has a tumor llx10cm.December CT check tumor on the 31st increases to 13xl3cm, and various symptoms increase the weight of day by day, are unable to leave the bed, and are diagnosed as late gastric cancer, lose operation and chemicotherapy chance.Sick age: 1 year.Examine the time: on March 12nd, 2011; Take Chinese medicine decoction of the present invention, once a day, and in (on forearm palmar band 2 cun of Neiguan acupoints, article two, between muscle), (below knee joint approximately 3 cun of the tsusanli acupoints, the about distance of 4 horizontal fingers) massage with medicine for external use, every day twice, used traditional Chinese medicine composition for treating of the present invention 20 days, self-induction gastric area pain symptom alleviates; Used traditional Chinese medicine composition for treating of the present invention 1 month, muscle power obviously increases, and oneself can get up and arrive outdoor stroll; Continue medication to 2011 year August, complexion is checked through hospital than very large change was arranged originally, cancerous cell is without diffusing phenomenon, and body weight increases, and quality of life has very large change during than western medical treatment, mood is more optimistic than originally, and life has been had new hope, in continuing at present to take.
In order to verify the effect of Chinese medicine composition of the present invention, we have carried out the experiment (embodiment 5) of medicine, and accurately data have been carried out statistics and mathematical analysis.
Concrete experimental result such as following table:
Table 1:
Table 2:
Prove through clinical trial, use Chinese medicine composition of the present invention to compare with the means of western medical treatment cancer, after curing, relapse rate is low, treatment means is more comprehensive thoroughly, have no side effect between the operating period, in treatment gastric cancer, can alleviate the symptoms such as the pain brought by gastric cancer, inappetence.Prove through clinical trial, Chinese drugs agentia effective percentage of the present invention is 98%, for early stage and late gastric cancer, good therapeutical effect is arranged all, and most of patients with gastric cancer are in medication about 5 days, and pain symptom has obviously and alleviates.For the early gastric cancer patient, adhere to using Chinese medicine composition of the present invention, can thoroughly remove focus about 4 months, the advanced gastric carcinoma patient is using Chinese medicine composition of the present invention can reach the purpose of controlling or curing cancer about 6 months, and for the late gastric cancer patient, use Chinese medicine composition of the present invention, when effectively controlling the cancerous cell high speed diffusion, the quality of life of residue life is improved, increase the confidence for future life.Therefore Chinese medicine composition of the present invention is a kind of medicine for the treatment of safely and effectively gastric cancer.
Claims (8)
1. a Chinese medicine composition for the treatment of gastric cancer, is characterized in that, takes off the primary raw material of stating weight proportion and be prepared from: Radix Notoginseng 3-9 part, Herba Solani Lyrati 15-30 part, Herba Agrimoniae 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 3-9 part, Rhizoma Pinelliae 3-10 part, Herba Hedyotidis Diffusae 15-30 part, Herba Scutellariae Barbatae 15-30 part, Radix Asparagi 10-20 part, Radix Ophiopogonis 10-20 part, Flos Sophorae 5-9 part, Radix Sophorae Tonkinensis 3-6 part, Rhizoma Corydalis 3-15 part, Rhizoma Atractylodis Macrocephalae 15-40 part, Rhizoma Curcumae Longae 10-30 part, Bulbus Allii Cepae 10-30 part.
2. Chinese medicine composition according to claim 1, is characterized in that, takes off the primary raw material of stating weight proportion and be prepared from: Radix Notoginseng 5-9 part, Herba Solani Lyrati 16-25 part, Herba Agrimoniae 15-25 part, Pseudobulbus Cremastrae Seu Pleiones 4-8 part, Rhizoma Pinelliae 4-8 part, Herba Hedyotidis Diffusae 18-28 part, Herba Scutellariae Barbatae 18-25 part, Radix Asparagi 12-18 part, Radix Ophiopogonis 14-18 part, Flos Sophorae 6-8 part, Radix Sophorae Tonkinensis 3.5-5 part, Rhizoma Corydalis 6-14 part, Rhizoma Atractylodis Macrocephalae 20-38 part, Rhizoma Curcumae Longae 15-28 part, Bulbus Allii Cepae 12-28 part.
3. Chinese medicine composition according to claim 1, take off the primary raw material of stating weight proportion and be prepared from: 8 parts of Radix Notoginseng, 20 parts of Herba Solani Lyratis, 20 parts of Herba Agrimoniaes, 6 parts of Pseudobulbus Cremastrae Seu Pleioness, 5 parts of the Rhizoma Pinelliaes, 20 parts of Herba Hedyotidis Diffusaes, 20 parts of Herba Scutellariae Barbataes, 15 parts of Radix Asparagis, 15 parts of Radix Ophiopogonis, 7 parts, Flos Sophorae, 4 parts of Radix Sophorae Tonkinensiss, 12 parts of Rhizoma Corydalis, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts, Rhizoma Curcumae Longae, 15 parts of Bulbus Allii Cepaes.
4. the preparation method of according to claim 1-3 arbitrary described Chinese medicine compositions, is characterized in that, step is as follows:
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, Bulbus Allii Cepae are smashed and be soaked in water 20-60 minute, boiled with high heat, change the slow fire heating and collect distillate or pass into vapor distillation 30-120 minute with distillation equipment, volatile oil and water are together distilled, collect distillate, standing 20-50 minute, distillate was cooled to 20-30 ℃, after get upper strata fluid, fluid is heated to 100 ℃-200 ℃, keep sterilization in 2-8 minute, be cooled to room temperature, after to be distributed into air-tight bottle standby;
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Rhizoma Pinelliae intense fire are fried open, turn 10-20 at a simmer minute, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Radix Ophiopogonis, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be fried in shallow oil 20-40 minute, leached medicinal liquid standby.
5. preparation method according to claim 4, is characterized in that, 1. step is smashed the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, Bulbus Allii Cepae and be soaked in water 30-50 minute, boiled with high heat, change slow fire and add thermal distillation or pass into vapor distillation 40-80 minute, volatile oil and water are together distilled, collect distillate, standing 25-40 minute, distillate was cooled to 25-28 ℃, after get upper strata fluid, fluid is heated to 120-180 ℃, keep sterilization in 3-6 minute, be cooled to room temperature, after to be distributed into air-tight bottle standby.
6. preparation method according to claim 4, it is characterized in that, 2. step is fried open Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Rhizoma Pinelliae intense fire, turn 12-18 at a simmer minute, then putting into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Radix Ophiopogonis, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis changes intense fire and is fried open, rear slow fire is continuous to be fried in shallow oil 25-35 minute, leached medicinal liquid standby.
7. preparation method according to claim 4, is characterized in that, 1. step is smashed the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, Bulbus Allii Cepae and be soaked in water 35 minutes, boiled with high heat, change slow fire and add thermal distillation or passed into vapor distillation 45 minutes, volatile oil and water are together distilled, collect distillate, standing 30 minutes, distillate was cooled to 26 ℃, after get upper strata fluid, fluid is heated to 150 ℃, keep sterilization in 4 minutes, be cooled to room temperature, after to be distributed into air-tight bottle standby.
8. preparation method according to claim 4, it is characterized in that, 2. step is fried open Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Rhizoma Pinelliae intense fire, turn 15 minutes at a simmer, then putting into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Radix Ophiopogonis, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis changes intense fire and is fried open, rear slow fire is continuous to be fried in shallow oil 30 minutes, leached medicinal liquid standby.
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