CN104474218A - Stomach invigorating and food retention removing instant granules for slowing cancer cell spreading, and preparation method thereof - Google Patents
Stomach invigorating and food retention removing instant granules for slowing cancer cell spreading, and preparation method thereof Download PDFInfo
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Abstract
The present invention discloses stomach invigorating and food retention removing instant granules for slowing cancer cell spreading. The stomach invigorating and food retention removing instant granules are characterized in that the stomach invigorating and food retention removing instant granules are prepared from the following main raw materials by weight: 3-9 parts of sagina japonica, 5-10 parts of solanum lyratum, 8-12 parts of coridius chinensis, 3-9 parts of green onion, 3-10 parts of hericium erinaceus, 15-30 parts of radix angelicae pubescentis, 1-5 parts of centipede, 10-20 parts of salvia miltiorrhiza, 10-20 parts of sappan wood, 5-9 parts of tuckahoe, and 4-8 parts of ligusticum chuanxiong hort. According to the present invention, the stomach invigorating and food retention removing instant granules have effects of significant gastric cancer effect, pain relieving, bleeding stopping, anti-cancer, anti-tumor, and cancer cell spreading slowing; and the stomach invigorating and food retention removing instant granules mainly select the local common herbs and the prices are low so as to reduce the financial burden on patients.
Description
Technical field
The invention belongs to traditional Chinese medicine field, especially relate to a kind of the stomach invigorating removing food stagnancy electuary and the method for making that slow down cancerous cell diffusion.
Background technology
Gastric cancer is one of cancer that in worldwide, sickness rate is the highest.Annual newly-increased 900,000 patients with gastric cancer in the whole world, have 700,000 people to die from gastric cancer simultaneously every year.The sickness rate of gastric cancer significantly raises along with the increase at age, and the peak age of morbidity was at 50 years old ~ 80 years old.Wherein, the sickness rate of male is 1.5 ~ 2.5 times of women, and mortality rate is only second to pulmonary carcinoma occupies second.Meanwhile, the incidence gastric cancer rate of women and mortality rate have the trend of rising.China is the district occurred frequently of gastric cancer, and gastric cancer annual loading and mortality rate are all more than 2 times of world average level.Second National coroner's inquest result according to sanitation Ministry tissue shows, and the mortality rate of Chinese gastric cancer accounts for all because of number of cancer deaths's 23.2%, close to 1/4th.
The symptom of gastric cancer: 1. early gastric cancer more than 70% non-evident sympton, along with the development of the state of an illness, nonspecific, to exactly like gastritis or gastric ulcer symptom can be engendered, comprise the glutted discomfort of epigastrium or dull pain, pantothenic acid, belch, feel sick, occasionally have vomiting, loss of appetite, melena etc.2. advanced gastric carcinoma symptom is shown in gastric area pain, is often gnawing property, with feed without obvious relation, also has similar peptic ulcer pain, can alleviate after feed.Epigastrium feeling of repletion, sense of heaviness, anorexia, stomachache, nausea,vomiting,diarrhea, become thin, anemia, edema, heating etc.Carcinoma of gastric cardia main manifestations is uncomfortable under xiphoid-process, pain or retrosternal pain, companion's dysphagia sense or dysphagia; At the bottom of stomach and the normal non-evident sympton of cardia inferior segment cancer, just arouse attention until the huge and diabrosis that necroses of tumor causes during upper gastrointestinal hemorrhage, or begin to give attention because of tumor-infiltrated extending to after cardia causes dysphagia; Body of stomach cancer is more common with intumescent, and pain discomfort occurs more late; Gastric antrum lesser curvature side is the most common with ulcer type cancer, therefore the symptom of epigastrium pain occurs comparatively early, when tumor prolong and pyloric ostium time, then can to cause nausea, the pyloric obstruction symptom such as vomiting.Cancerous protuberance diffusion transfer can cause the transfer of ascites, hepatomegaly, jaundice and lung, brain, the heart, prostate, ovary, bone marrow etc. and occur corresponding symptom.
Now for the treatment of gastric cancer, doctor trained in Western medicine adopts operative treatment, radiotherapy or chemotherapy three one usually, or the method for together treating.Operative treatment: generally include radical surgery, palliative operation, detecting property is performed the operation.Namely take operation as means complete removal of lesions or cut-out focus, reach the method for curing or controlling cancer.Radiotherapy: be called for short radiotherapy, be utilize high-energy electromagnetic radiation line to act on life entity, biomolecular structure is changed, reach a kind of Therapeutic Method of destruction of cancer cells object.Radiation can Therapeutic cancer be because cancerous cell is responsive to lonizing radiation.The lonizing radiation applied clinically at present have x-ray to treat and r line treats two kinds.Chemotherapy: chemotherapy takes medicine intravascular to whole body, has impact to health all cells.This therapy is sometimes also referred to as " born of the same parents poison therapy ", because medicine used is all harmful, or even band toxicity, whether cells in vivo, no matter malignant cell, be all damaged.
No matter be adopt operative treatment, radiotherapy or adopt chemotherapy, all great burden caused to the health of patient, and costly, sufferer is born painful large.
Summary of the invention
Along with the development of Chinese Chinese medicine, in Cure and control gastric cancer, people gradually appreciate treatment by Chinese herbs stomach cancer treatment procedure and have no side effect, patient bears painful little, and the advantage that cost is saved relatively, for the present situation of existing western medical treatment cancer, an object of the present invention is the stomach invigorating removing food stagnancy electuary providing a kind of Therapeutic cancer, there is feature easy to operate, evident in efficacy, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of stomach invigorating removing food stagnancy electuary slowing down cancerous cell diffusion, take off the primary raw material stating weight proportion to be prepared from: Herba Saginae Japonicae 3-9 part, Herba Solani Lyrati 5-10 part, Aspongopus 8-12 part, Herba Alii fistulosi 3-9 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 3-10 part, Radix Angelicae Pubescentis 15-30 part, Scolopendra 1-5 part, Radix Salviae Miltiorrhizae 10-20 part, Lignum Sappan 10-20 part, Poria 5-9 part, Rhizoma Chuanxiong 4-8 part.
Slow down a stomach invigorating removing food stagnancy electuary for cancerous cell diffusion, preferred scheme, takes off the primary raw material stating weight proportion and is prepared from: Herba Saginae Japonicae 5-9 part, Herba Solani Lyrati 8-9 part, Aspongopus 15-25 part, Herba Alii fistulosi 4-8 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 4-8 part, Radix Angelicae Pubescentis 18-28 part, Scolopendra 2-4 part, Radix Salviae Miltiorrhizae 12-18 part, Lignum Sappan 14-18 part, Poria 6-8 part, Rhizoma Chuanxiong 5-7 part.
Slow down a stomach invigorating removing food stagnancy electuary for cancerous cell diffusion, best scheme, takes off the primary raw material stating weight proportion and is prepared from: Herba Saginae Japonicae 8 parts, Herba Solani Lyrati 7 parts, Aspongopus 20 parts, Herba Alii fistulosi 6 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 5 parts, Radix Angelicae Pubescentis 20 parts, Scolopendra 3 parts, Radix Salviae Miltiorrhizae 15 parts, Lignum Sappan 15 parts, 7 parts, Poria, Rhizoma Chuanxiong 6 parts.
Slow down a preparation method for the stomach invigorating removing food stagnancy electuary of cancerous cell diffusion, be prepared from primarily of following step:
(1) by Aspongopus and the Scolopendra hot-water soak 10-30 minute with 60-80 DEG C, boiled with high heat, change after slow fire adds thermal distillation 40-60 minute and collect distillate, leave standstill 1-2 hour, distillate is cooled to 10 DEG C, keeps sterilizing stand-by in 1-5 minute, and the Aspongopus after distillation and Scolopendra are dried, grind to form smalls, cross 60-100 mesh sieve;
(2) Herba Alii fistulosi is cut into the block of small rice grain size, is placed in close grenadine cloth, is pounded Herba Alii fistulosi mud with rolling pin, ultraviolet-sterilization 2-6 minute, stand-by;
(3) Radix Salviae Miltiorrhizae, Lignum Sappan, Poria and Rhizoma Chuanxiong are cut into block, are placed in non iron container, add the warm water being blended into Mel, sealing and standing 1-3 hour, taking-up cools, and is placed in the iron pan that dryouies, fries 10-20 minute, cool, become smalls stand-by with mortar grinder;
(4) Herba Solani Lyrati and Hericium erinaceus (Bull. Ex Fr.) Pers. are placed in marmite, add step (1) gained distillate and soak 20-40 minute, intense fire is fried open, and boils 3-8 minute, turn 15-30 minute at a simmer, then after putting into Herba Saginae Japonicae, Radix Angelicae Pubescentis, slow fire is continuous decocts 10 minutes, and leach to obtain medicinal liquid 1, filtering residue decocts with water 40-60 minute again, leach to obtain medicinal liquid 2, after filtrate 1 is mixed homogeneously with filtrate 2, leave standstill 4-6 hour, get supernatant;
(5) step (1) gained smalls, step (2) gained Herba Alii fistulosi mud and step (3) gained smalls are added in step (4) gained supernatant, little fire decocts while stir, in time decocting into thick paste, cease fire stand-by;
(6) by step (5) gained thick paste dry 1-3 hour at 50-70 DEG C, pack and obtain electuary.
Above-mentioned preparation method, step (1) by Aspongopus and Scolopendra with 65-75 DEG C hot-water soak 15-25 minute (preferred, by the hot-water soak 20 minutes with 70 DEG C of Aspongopus and Scolopendra).
Above-mentioned preparation method, step (1) distillate is cooled to 10 DEG C, keeps within 2-4 minute, sterilize stand-by (preferred, distillate is cooled to 10 DEG C, keeps sterilizing stand-by in 3 minutes).
Above-mentioned preparation method, step (2) Herba Alii fistulosi mud ultraviolet-sterilization 3-5 minute (preferred, Herba Alii fistulosi mud ultraviolet-sterilization 4 minutes).
Above-mentioned preparation method, step (3) sealing and standing 1.5-2.5 hour (preferred, sealing and standing 2 hours).
Above-mentioned preparation method, step (4) boils 5-7 minute, turns 20-25 at a simmer minute (preferred, to boil 6 minutes, turn 23 minutes at a simmer).
Above-mentioned preparation method, step (6) gained thick paste is dry 1.5-2.5 hour (preferred, gained thick paste at 60 DEG C dry 2 hours) at 55-65 DEG C.
This stomach invigorating removing food stagnancy electuary, to gastric cancer Be very effective, not only has effect of pain relieving, hemostasis, also has anticancer antineoplastic action.The local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The pharmacological effect of each crude drug is respectively:
Herba Saginae Japonicae: for being the herb of Caryophyllaceae sagina Herba Saginae Japonicae.Composition: cold volatile oil, the sweet and flavone of soap.Pharmacology: the effect with low anticancer, has antitussive, clears phlegm.The property of medicine: bitter, pungent, cool.Return liver, stomach warp.Function cures mainly: removing pathogenic heat from blood and toxic substance from the body, killing parasites for relieving itching.
Aspongopus: have another name called black pocket worm, wind plate worm, for Pentatomiddae Aspongopus belongs to the dry Scorpio of animal Aspongopus.The property of medicine: this product is hexagonal shape flat ellipse, and abdominal part brownish red is to brownish black, and matter is crisp, acrid in the mouth, salty, warm in nature.Composition: fatty, protein and chitin etc.Find according to modern pharmacological research, this medical instrument has antibacterial, anticancer, promoting the circulation of QI to relieve pain, warming the kidney to invigorate YANG effect, for incoordination between the liver and stomach, and the lumbago that breast side of body epigastric distending pain and insufficiency of kidney-YANG cause.
Herba Alii fistulosi: another name and thing grass, onion, dish primary, HUOCONG, the four seasons Herba Alii fistulosi.Flavor efficacy is pungent, and temperature, enters lung, stomach warp.Exterior-excess hollow, rise to fall more and lack, merit is specially dispersed and is activated yang, can expelling wind and cold pathogens, and diaphoresis expelling pathogenic factors from muscles, is used for the treatment of the mild of typhoid fever, cold and heat headache; Again can item, sharp key, relieving constipation, activate yang gas and loose YIN-cold, be used for the treatment of QI and blood cohesion, dizzy headache, QI stagnated by cold, abdominal distention is suffered from abdominal pain, and bladder qi dysfunction and dysuria etc.; In addition still tool removing toxic substances, hemostatic function.Energy activating yang to invigorate blood circulation, anthelmintic removing toxic substances, relieving the exterior syndrome by diaphoresis.Cure mainly the diseases such as anemofrigid cold mild, carbuncle sore tumefacting virus, dysentery faint pulse, cold coagulation stomachache, dysuria, have good therapeutical effect to flu, wind and cold, headache, YIN-cold stomachache, malnutrition due to parasitic infestation internal resistance, dysentery etc.1. antipyretic, eliminate the phlegm: the volatilization wet goods effective ingredient of Herba Alii fistulosi, have and stimulate health sweat gland, reach the effect of diaphoresis heat radiation; Scallion oil stimulates upper respiratory tract, makes sticky expectorant be easy to bring up.2. facilitating digestion absorbs: Herba Alii fistulosi also has the effect stimulating body digestive juice secretion, can spleen benefiting and stimulating the appetite, appetite stimulator.3. antibacterial, antiviral.4. cancer-resisting.
Hericium erinaceus (Bull. Ex Fr.) Pers.: base is former: be the sporophore of hedgehog fungus section Hericium fungus Hericium erinaceus (Bull. Ex Fr.) Pers., Hydnum.Composition: containing Hericium erinaceus (Bull. Ex Fr.) Pers. Ketone A, B, C, D, E, F, G, H in Hericium erinaceus, Hericium erinaceus (Bull. Ex Fr.) Pers. alkali etc.Dry sporophore is containing protein, lipid, fiber and glucosan.Also containing sterols: ergosterol etc.Mycelium culture contains Hericium erinaceus (Bull. Ex Fr.) Pers. pyrone A, B etc.The property of medicine: " national Chinese herbal medicine compilation ": " sweet, flat." function cures mainly: strengthening the spleen and nourishing the stomach, calms the nerves, anticancer.Cure mainly body void weak, dyspepsia, insomnia, gastroduodenal ulcer, chronic gastritis, digestive tract tumor.
Radix Angelicae Pubescentis: be the root of the heavy tooth Radix Angelicae Sinensis of Umbelliferae archangel.Composition: containing coumarin kind compound, volatile oil, acetas, angelol, thymol.Pharmacology: play a very important role to cardiovascular system, has the effect of blood pressure lowering, can promote hematoblastic gathering, have good analgesia and antiinflammatory action.There is anti-light quick effect, have significant curative effect to opposing tumor, anti-inflammation is also played a very important role.The property of medicine: bitter, tepor, pungent.Return kidney, urinary bladder channel.Function cures mainly: expelling wind and dampness, dispersing cold for relieving pain.
Scolopendra: Scolopendra is Lu Sheng arthropod, and health is made up of many body segments, on each joint, all length has step, therefore is that polypody is biological.Relieve internal heat anticancer, for the long-pending poison of carcinoma, relieving spasm by calming endogenous wind, for wind disease convulsion pain.
Radix Salviae Miltiorrhizae: Radix Salviae Miltiorrhizae has another name called Radix Salviae Miltiorrhizae, Radix Salviae Miltiorrhizae, Arisaema balansae Engl. etc.Nature and flavor are bitter, are slightly cold.GUIXIN, Liver Channel.There is stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Lignum Sappan: sweet, salty, flat.GUIXIN, liver, spleen channel.[function cures mainly] promoting the circulation of blood blood stasis dispelling, reducing swelling and alleviating pain.For amenorrhea dysmenorrhea, postpartum stagnation, breast ventral spine pain, wound swells and ache.
Olibanum: Olibanum, real name smokes land, and the smoked Lu Xiang of another name, horse hair is fragrant, nipple is fragrant, the perfume (or spice) that collapses, sky pool is fragrant, Moller is fragrant, many gals Luo Xiang etc., is the cured resin of Burseraceae aiphyllium.Because it drips into mamillary, thus fragrant also known as nipple.Regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Poria: Poria has another name called: beautiful spirit, Fu Tu, Poria, Fu Ling, Fu Ling, volt Tu, pine fat, deep red morning lies prostrate tire, Poria, Fu rabbit, loose potato, Masson Pine potato, Song Ling.Meridian distribution of property and flavor: sweet, light is flat.GUIXIN, spleen, kidney channel, Poria can spleen invigorating, again can eliminating dampness by diuresis, can be used as again tonifying the lung spleen, controls the adjuvant of the deficiency of vital energy.For cough due to fluid-retention, phlegm-damp enters network, aching pain in should and back.
Rhizoma Chuanxiong: Rhizoma Chuanxiong is a kind of Chinese medicinal plant, is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, the pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, and the up mountain peak that reaches is pushed up; Enter blood system again, descendingly reach the sea of blood.Blood circulation promoting and blood stasis dispelling effect is extensive, the suitable various disease of stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.For pain in chest and hypochondrium, rheumatic arthralgia, lump in the abdomen lumps, and skin infection swells and ache, and falls and flutters the pain of injury, menoxenia, amenorrhea dysmenorrhea, puerperal the disease such as stasis of blood pain.The pungent loose temperature of Rhizoma Chuanxiong is led to, function blood circulation promoting and blood stasis dispelling.
Stomach invigorating removing food stagnancy electuary of the present invention debates the principle of disease treatment based on Chinese medicine.Treatment is more comprehensive, and affected area administration is more rapid, lasting medicine, the gastric cancer prescription for the treatment of both the principal and secondary aspects of a disease.Fabulous therapeutical effect is had, for thin and weak health has fabulous opsonic action because of long-term chemicotherapy to gastric cancer.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 one kinds slows down the stomach invigorating removing food stagnancy electuary of cancerous cell diffusion, takes off the primary raw material stating weight proportion and is prepared from: Herba Saginae Japonicae 3 parts, Herba Solani Lyrati 5 parts, Aspongopus 8 parts, Herba Alii fistulosi 3 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 3 parts, Radix Angelicae Pubescentis 15 parts, Scolopendra 1 part, Radix Salviae Miltiorrhizae 10 parts, Lignum Sappan 10 parts, 5 parts, Poria, Rhizoma Chuanxiong 4 parts.
The above-mentioned preparation method slowing down the stomach invigorating removing food stagnancy electuary of cancerous cell diffusion, step is as follows:
(1) by the hot-water soak 10 minutes with 60 DEG C of Aspongopus and Scolopendra, boiled with high heat, change slow fire to add thermal distillation and collect distillate after 40 minutes, leave standstill 1 hour, distillate is cooled to 10 DEG C, keeps sterilizing stand-by in 1 minute, and the Aspongopus after distillation and Scolopendra are dried, grind to form smalls, cross 60 mesh sieves;
(2) Herba Alii fistulosi is cut into the block of small rice grain size, is placed in close grenadine cloth, is pounded Herba Alii fistulosi mud with rolling pin, ultraviolet-sterilization 2 minutes, stand-by;
(3) Radix Salviae Miltiorrhizae, Lignum Sappan, Poria and Rhizoma Chuanxiong are cut into block, are placed in non iron container, add the warm water being blended into Mel, sealing and standing 1 hour, taking-up cools, and is placed in the iron pan that dryouies, fries 10 minutes, cool, become smalls stand-by with mortar grinder;
(4) Herba Solani Lyrati and Hericium erinaceus (Bull. Ex Fr.) Pers. are placed in marmite, add step (1) gained distillate and soak 20 minutes, intense fire is fried open, and boils 3 minutes, turn 15 minutes at a simmer, then after putting into Herba Saginae Japonicae, Radix Angelicae Pubescentis, slow fire is continuous decocts 10 minutes, and leach to obtain medicinal liquid 1, filtering residue decocts with water 40 minutes again, leach to obtain medicinal liquid 2, after filtrate 1 is mixed homogeneously with filtrate 2, leave standstill 4 hours, get supernatant;
(5) step (1) gained smalls, step (2) gained Herba Alii fistulosi mud and step (3) gained smalls are added in step (4) gained supernatant, little fire decocts while stir, in time decocting into thick paste, cease fire stand-by;
(6) by step (5) gained thick paste at 50 DEG C dry 1 hour, pack and obtain electuary.
Model case one: Liu XX, man, 45 years old, people from Jiyang, Shandong Province.Symptom: on November 29th, 2010 because of hepatic region severe pain go to a doctor, check find liver have a tumor 11x10cm.December CT on the 31st checks tumor and increases to 13x13cm, and various symptom increases the weight of day by day, is unable to leave the bed, and is diagnosed as late gastric cancer, loses operation and chemicotherapy chance.
Every day twice, use stomach invigorating removing food stagnancy Chongji for Treatment of the present invention 10 days, self-induction gastric area pain symptom alleviates; Use stomach invigorating removing food stagnancy Chongji for Treatment of the present invention 2 months, muscle power obviously increases, and oneself can get up and arrive outdoor stroll; Continue medication 5 months, complexion is than originally there being very large change, and through hospital's check, cancerous cell is without diffusing phenomenon, and body weight increases, and quality of life, mood was more optimistic than originally than there being very large change during western medical treatment, had had new hope to life, in continuing at present to take.
Embodiment 2 one kinds slows down the stomach invigorating removing food stagnancy electuary of cancerous cell diffusion, takes off the primary raw material stating weight proportion and is prepared from: Herba Saginae Japonicae 9 parts, Herba Solani Lyrati 10 parts, Aspongopus 12 parts, Herba Alii fistulosi 9 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 10 parts, Radix Angelicae Pubescentis 30 parts, Scolopendra 5 parts, Radix Salviae Miltiorrhizae 20 parts, Lignum Sappan 20 parts, 9 parts, Poria, Rhizoma Chuanxiong 8 parts.
(1) by the hot-water soak 30 minutes with 80 DEG C of Aspongopus and Scolopendra, boiled with high heat, change slow fire to add thermal distillation and collect distillate after 60 minutes, leave standstill 2 hours, distillate is cooled to 10 DEG C, keeps sterilizing stand-by in 5 minutes, and the Aspongopus after distillation and Scolopendra are dried, grind to form smalls, cross 100 mesh sieves;
(2) Herba Alii fistulosi is cut into the block of small rice grain size, is placed in close grenadine cloth, is pounded Herba Alii fistulosi mud with rolling pin, ultraviolet-sterilization 6 minutes, stand-by;
(3) Radix Salviae Miltiorrhizae, Lignum Sappan, Poria and Rhizoma Chuanxiong are cut into block, are placed in non iron container, add the warm water being blended into Mel, sealing and standing 3 hours, taking-up cools, and is placed in the iron pan that dryouies, fries 20 minutes, cool, become smalls stand-by with mortar grinder;
(4) Herba Solani Lyrati and Hericium erinaceus (Bull. Ex Fr.) Pers. are placed in marmite, add step (1) gained distillate and soak 40 minutes, intense fire is fried open, and boils 8 minutes, turn 30 minutes at a simmer, then after putting into Herba Saginae Japonicae, Radix Angelicae Pubescentis, slow fire is continuous decocts 10 minutes, and leach to obtain medicinal liquid 1, filtering residue decocts with water 60 minutes again, leach to obtain medicinal liquid 2, after filtrate 1 is mixed homogeneously with filtrate 2, leave standstill 6 hours, get supernatant;
(5) step (1) gained smalls, step (2) gained Herba Alii fistulosi mud and step (3) gained smalls are added in step (4) gained supernatant, little fire decocts while stir, in time decocting into thick paste, cease fire stand-by;
(6) by step (5) gained thick paste at 70 DEG C dry 3 hours, pack and obtain electuary.
Model case two: Liu XX, female, 48 years old, Liaocheng, Shandong Province personage, did manual work in other places always, occurs suddenly the symptom that the whole body ache of unknown cause is unable, just started to swallow pain obstinate, after with the symptom of deep coughs, spitting of blood, the obvious enlargement of throat.Intermediate gastric carcinoma is diagnosed as through examination in hospital.Due to the chance having missed operation when finding, so doctor advised takes gained stomach invigorating removing food stagnancy electuary of the present invention.
Use stomach invigorating removing food stagnancy Chongji for Treatment of the present invention 10 days, spitting of blood symptom alleviates, and pharyngeal pain is alleviated to some extent; Use stomach invigorating removing food stagnancy Chongji for Treatment of the present invention 1 month, laryngeal neoplasm reduces; Use stomach invigorating removing food stagnancy Chongji for Treatment of the present invention 5 months, after hospital's check, find tumor atrophy, in continuing at present to take.
Embodiment 3 one kinds slows down the stomach invigorating removing food stagnancy electuary of cancerous cell diffusion, takes off the primary raw material stating weight proportion and is prepared from: Herba Saginae Japonicae 5 parts, Herba Solani Lyrati 8 parts, Aspongopus 15 parts, Herba Alii fistulosi 4 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 4 parts, Radix Angelicae Pubescentis 18 parts, Scolopendra 2 parts, Radix Salviae Miltiorrhizae 12 parts, Lignum Sappan 14 parts, 6 parts, Poria, Rhizoma Chuanxiong 5 parts.
(1) by the hot-water soak 15 minutes with 65 DEG C of Aspongopus and Scolopendra, boiled with high heat, change slow fire to add thermal distillation and collect distillate after 45 minutes, leave standstill 1.3 hours, distillate is cooled to 10 DEG C, keeps sterilizing stand-by in 2 minutes, and the Aspongopus after distillation and Scolopendra are dried, grind to form smalls, cross 70 mesh sieves;
(2) Herba Alii fistulosi is cut into the block of small rice grain size, is placed in close grenadine cloth, is pounded Herba Alii fistulosi mud with rolling pin, ultraviolet-sterilization 3 minutes, stand-by;
(3) Radix Salviae Miltiorrhizae, Lignum Sappan, Poria and Rhizoma Chuanxiong are cut into block, are placed in non iron container, add the warm water being blended into Mel, sealing and standing 1.5 hours, taking-up cools, and is placed in the iron pan that dryouies, fries 13 minutes, cool, become smalls stand-by with mortar grinder;
(4) Herba Solani Lyrati and Hericium erinaceus (Bull. Ex Fr.) Pers. are placed in marmite, add step (1) gained distillate and soak 25 minutes, intense fire is fried open, and boils 5 minutes, turn 18 minutes at a simmer, then after putting into Herba Saginae Japonicae, Radix Angelicae Pubescentis, slow fire is continuous decocts 10 minutes, and leach to obtain medicinal liquid 1, filtering residue decocts with water 45 minutes again, leach to obtain medicinal liquid 2, after filtrate 1 is mixed homogeneously with filtrate 2, leave standstill 4.5 hours, get supernatant;
(5) step (1) gained smalls, step (2) gained Herba Alii fistulosi mud and step (3) gained smalls are added in step (4) gained supernatant, little fire decocts while stir, in time decocting into thick paste, cease fire stand-by;
(6) by step (5) gained thick paste at 55 DEG C dry 1.5 hours, pack and obtain electuary.
Model case three: king xx, female, 39 years old, Sishui County, Jining City in Shandong Province.Eating, it is difficult to swallow, and weight loss, intermittent stomach pain, with serious vomiting, goes hospital diagnosis to be early gastric cancer.Sick age: 5 months.Use stomach invigorating removing food stagnancy Chongji for Treatment of the present invention 10 days, symptoms of emesis alleviates, and pain has very large alleviation; Use stomach invigorating removing food stagnancy Chongji for Treatment of the present invention 3 months, function of deglutition recovers completely, obviously diminishes through examination in hospital tumor.Use stomach invigorating removing food stagnancy Chongji for Treatment of the present invention 10 months, tumor disappearance; Be used alone volatile oil and consolidate one month, so far without recurrence.
Embodiment 4 one kinds slows down the stomach invigorating removing food stagnancy electuary of cancerous cell diffusion, takes off the primary raw material stating weight proportion and is prepared from: Herba Saginae Japonicae 9 parts, Herba Solani Lyrati 9 parts, Aspongopus 25 parts, Herba Alii fistulosi 8 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 8 parts, Radix Angelicae Pubescentis 28 parts, Scolopendra 4 parts, Radix Salviae Miltiorrhizae 18 parts, Lignum Sappan 18 parts, 8 parts, Poria, Rhizoma Chuanxiong 7 parts.
(1) by the hot-water soak 25 minutes with 75 DEG C of Aspongopus and Scolopendra, boiled with high heat, change slow fire to add thermal distillation and collect distillate after 55 minutes, leave standstill 1.8 hours, distillate is cooled to 10 DEG C, keeps sterilizing stand-by in 1-5 minute, and the Aspongopus after distillation and Scolopendra are dried, grind to form smalls, cross 90 mesh sieves;
(2) Herba Alii fistulosi is cut into the block of small rice grain size, is placed in close grenadine cloth, is pounded Herba Alii fistulosi mud with rolling pin, ultraviolet-sterilization 5 minutes, stand-by;
(3) Radix Salviae Miltiorrhizae, Lignum Sappan, Poria and Rhizoma Chuanxiong are cut into block, are placed in non iron container, add the warm water being blended into Mel, sealing and standing 2.5 hours, taking-up cools, and is placed in the iron pan that dryouies, fries 18 minutes, cool, become smalls stand-by with mortar grinder;
(4) Herba Solani Lyrati and Hericium erinaceus (Bull. Ex Fr.) Pers. are placed in marmite, add step (1) gained distillate and soak 35 minutes, intense fire is fried open, and boils 7 minutes, turn 25 minutes at a simmer, then after putting into Herba Saginae Japonicae, Radix Angelicae Pubescentis, slow fire is continuous decocts 10 minutes, and leach to obtain medicinal liquid 1, filtering residue decocts with water 55 minutes again, leach to obtain medicinal liquid 2, after filtrate 1 is mixed homogeneously with filtrate 2, leave standstill 5.5 hours, get supernatant;
(5) step (1) gained smalls, step (2) gained Herba Alii fistulosi mud and step (3) gained smalls are added in step (4) gained supernatant, little fire decocts while stir, in time decocting into thick paste, cease fire stand-by;
(6) by step (5) gained thick paste at 65 DEG C dry 2.5 hours, pack and obtain electuary.
Model case four: pungent xx, female, 47 years old, people from Liaocheng of Shandong Province.Symptom: the regular dull pain of stomach, belch, vomiting, do not have appetite, and lean body mass is weak.Going to hospital to make a definite diagnosis is gastric cancer mid-term, do chemotherapy 2 months, treatment is stopped because standing and hold untoward reaction and high expense that can't stand chemotherapy, once other drug treatment was accepted after stopping chemotherapy, but effect is all not obvious, see unintentionally stomach invigorating removing food stagnancy electuary of the present invention on the net, just buy 1 month take.
Take stomach invigorating removing food stagnancy Chongji for Treatment of the present invention 5 days, pain symptom alleviates, and appetite is recovered to some extent; Use stomach invigorating removing food stagnancy Chongji for Treatment of the present invention 4 months, go to hospital to check cancerous cell and do not spread; Use stomach invigorating removing food stagnancy Chongji for Treatment of the present invention 5 months, tumor cell diminishes, and current cancerous cell is substantially without diffusion.
Embodiment 5 one kinds slows down the stomach invigorating removing food stagnancy electuary of cancerous cell diffusion, takes off the primary raw material stating weight proportion and is prepared from: Herba Saginae Japonicae 8 parts, Herba Solani Lyrati 7 parts, Aspongopus 20 parts, Herba Alii fistulosi 6 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 5 parts, Radix Angelicae Pubescentis 20 parts, Scolopendra 3 parts, Radix Salviae Miltiorrhizae 15 parts, Lignum Sappan 15 parts, 7 parts, Poria, Rhizoma Chuanxiong 6 parts.
(1) by the hot-water soak 20 minutes with 70 DEG C of Aspongopus and Scolopendra, boiled with high heat, change slow fire to add thermal distillation and collect distillate after 50 minutes, leave standstill 1.5 hours, distillate is cooled to 10 DEG C, keeps sterilizing stand-by in 3 minutes, and the Aspongopus after distillation and Scolopendra are dried, grind to form smalls, cross 80 mesh sieves;
(2) Herba Alii fistulosi is cut into the block of small rice grain size, is placed in close grenadine cloth, is pounded Herba Alii fistulosi mud with rolling pin, ultraviolet-sterilization 4 minutes, stand-by;
(3) Radix Salviae Miltiorrhizae, Lignum Sappan, Poria and Rhizoma Chuanxiong are cut into block, are placed in non iron container, add the warm water being blended into Mel, sealing and standing 2 hours, taking-up cools, and is placed in the iron pan that dryouies, fries 15 minutes, cool, become smalls stand-by with mortar grinder;
(4) Herba Solani Lyrati and Hericium erinaceus (Bull. Ex Fr.) Pers. are placed in marmite, add step (1) gained distillate and soak 30 minutes, intense fire is fried open, and boils 3-8 minute, turn 23 minutes at a simmer, then after putting into Herba Saginae Japonicae, Radix Angelicae Pubescentis, slow fire is continuous decocts 10 minutes, and leach to obtain medicinal liquid 1, filtering residue decocts with water 50 minutes again, leach to obtain medicinal liquid 2, after filtrate 1 is mixed homogeneously with filtrate 2, leave standstill 5 hours, get supernatant;
(5) step (1) gained smalls, step (2) gained Herba Alii fistulosi mud and step (3) gained smalls are added in step (4) gained supernatant, little fire decocts while stir, in time decocting into thick paste, cease fire stand-by;
(6) by step (5) gained thick paste at 60 DEG C dry 2 hours, pack and obtain electuary.
Experimental example: in order to verify the effect of stomach invigorating removing food stagnancy electuary of the present invention, we are in 10 hospitals, have chosen the experiment (embodiment 5) that 300 routine patients with gastric cancer have carried out medicine, be divided into matched group and experimental group, matched group 100 people, experimental group 200 people, matched group takes the Western medicine of other treatment cancer (as Erlotinib, Fugerel, hundred scholars are glad, anticancer pill ball, the medicine of the conventional therapy cancers such as purple imperial gold plaque), experimental group takes gained electuary of the present invention, instructions of taking: be the therapeutic effect making the present invention reach best, get the electuary 3-10g warm boiled water prepared at every turn, sugaring that can be suitable according to individual taste, in sooner or later taking half an hour after meal, it within 10 days, is a course for the treatment of.Criterion: effectively: after taking medicine, cancerous cell is controlled substantially, does not have the phenomenon spread, invalid: cancer rill number is still unchanged, and has carried out statistics and mathematical analysis to data accurately.
Specific experiment result is as following table:
Table 1:
Prove through clinical trial, use stomach invigorating removing food stagnancy electuary of the present invention compared with the means of western medical treatment cancer, control recurrence rate after healing low, treatment means is more comprehensive thoroughly, have no side effect between the operating period, while treatment gastric cancer, the symptom such as pain, inappetence brought by gastric cancer can be alleviated.Prove through clinical trial, Chinese drugs agentia effective percentage of the present invention is 99%, all has good therapeutical effect for early stage and late gastric cancer, and most of patients with gastric cancer was medication about 5 days, and pain symptom has and obviously alleviates.For early gastric cancer patient, adhere to using stomach invigorating removing food stagnancy electuary of the present invention, substantially be inhibited at about 4 months cancer rills, use stomach invigorating removing food stagnancy electuary of the present invention, while effectively controlling cancerous cell high speed diffusion, the quality of life of residue life can be made to improve, increase the confidence for future life.Therefore stomach invigorating removing food stagnancy electuary of the present invention is a kind of medicine for the treatment of gastric cancer safely and effectively.
Claims (10)
1. one kind is slowed down the stomach invigorating removing food stagnancy electuary of cancerous cell diffusion, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Herba Saginae Japonicae 3-9 part, Herba Solani Lyrati 5-10 part, Aspongopus 8-12 part, Herba Alii fistulosi 3-9 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 3-10 part, Radix Angelicae Pubescentis 15-30 part, Scolopendra 1-5 part, Radix Salviae Miltiorrhizae 10-20 part, Lignum Sappan 10-20 part, Poria 5-9 part, Rhizoma Chuanxiong 4-8 part.
2. the stomach invigorating removing food stagnancy electuary slowing down cancerous cell diffusion according to claim 1, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Herba Saginae Japonicae 5-9 part, Herba Solani Lyrati 8-9 part, Aspongopus 15-25 part, Herba Alii fistulosi 4-8 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 4-8 part, Radix Angelicae Pubescentis 18-28 part, Scolopendra 2-4 part, Radix Salviae Miltiorrhizae 12-18 part, Lignum Sappan 14-18 part, Poria 6-8 part, Rhizoma Chuanxiong 5-7 part.
3. the stomach invigorating removing food stagnancy electuary slowing down cancerous cell diffusion according to claim 1, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Herba Saginae Japonicae 8 parts, Herba Solani Lyrati 7 parts, Aspongopus 20 parts, Herba Alii fistulosi 6 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 5 parts, Radix Angelicae Pubescentis 20 parts, Scolopendra 3 parts, Radix Salviae Miltiorrhizae 15 parts, Lignum Sappan 15 parts, 7 parts, Poria, Rhizoma Chuanxiong 6 parts.
4. the preparation method slowing down the stomach invigorating removing food stagnancy electuary of cancerous cell diffusion according to any one of claim 1-3, is characterized in that: be prepared from primarily of following step:
(1) by Aspongopus and the Scolopendra hot-water soak 10-30 minute with 60-80 DEG C, boiled with high heat, change after slow fire adds thermal distillation 40-60 minute and collect distillate, leave standstill 1-2 hour, distillate is cooled to 10 DEG C, keeps sterilizing stand-by in 1-5 minute, and the Aspongopus after distillation and Scolopendra are dried, grind to form smalls, cross 60-100 mesh sieve;
(2) Herba Alii fistulosi is cut into the block of small rice grain size, is placed in close grenadine cloth, is pounded Herba Alii fistulosi mud with rolling pin, ultraviolet-sterilization 2-6 minute, stand-by;
(3) Radix Salviae Miltiorrhizae, Lignum Sappan, Poria and Rhizoma Chuanxiong are cut into block, are placed in non iron container, add the warm water being blended into Mel, sealing and standing 1-3 hour, taking-up cools, and is placed in the iron pan that dryouies, fries 10-20 minute, cool, become smalls stand-by with mortar grinder;
(4) Herba Solani Lyrati and Hericium erinaceus (Bull. Ex Fr.) Pers. are placed in marmite, add step (1) gained distillate and soak 20-40 minute, intense fire is fried open, and boils 3-8 minute, turn 15-30 minute at a simmer, then after putting into Herba Saginae Japonicae, Radix Angelicae Pubescentis, slow fire is continuous decocts 10 minutes, and leach to obtain medicinal liquid 1, filtering residue decocts with water 40-60 minute again, leach to obtain medicinal liquid 2, after filtrate 1 is mixed homogeneously with filtrate 2, leave standstill 4-6 hour, get supernatant;
(5) step (1) gained smalls, step (2) gained Herba Alii fistulosi mud and step (3) gained smalls are added in step (4) gained supernatant, little fire decocts while stir, in time decocting into thick paste, cease fire stand-by;
(6) by step (5) gained thick paste dry 1-3 hour at 50-70 DEG C, pack and obtain electuary.
5. preparation method according to claim 4, is characterized in that: step (1) was by Aspongopus and Scolopendra 65-75 DEG C hot-water soak 15-25 minute (preferred, by the hot-water soak 20 minutes with 70 DEG C of Aspongopus and Scolopendra).
6. preparation method according to claim 4, is characterized in that: step (1) distillate is cooled to 10 DEG C, keeps within 2-4 minute, sterilize stand-by (preferred, distillate is cooled to 10 DEG C, keeps sterilizing stand-by in 3 minutes).
7. preparation method according to claim 4, is characterized in that: step (2) Herba Alii fistulosi mud ultraviolet-sterilization 3-5 minute (preferred, Herba Alii fistulosi mud ultraviolet-sterilization 4 minutes).
8. preparation method according to claim 4, is characterized in that: step (3) sealing and standing 1.5-2.5 hour (preferred, sealing and standing 2 hours).
9. preparation method according to claim 4, is characterized in that: step (4) boils 5-7 minute, turns 20-25 at a simmer minute (preferred, to boil 6 minutes, turn 23 minutes at a simmer).
10. preparation method according to claim 4, is characterized in that: step (6) gained thick paste is dry 1.5-2.5 hour (preferred, gained thick paste at 60 DEG C dry 2 hours) at 55-65 DEG C.
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| CN105214027A (en) * | 2015-09-29 | 2016-01-06 | 陈大伟 | A kind of capsule for the treatment of digestive tract tumor and preparation method thereof |
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Application publication date: 20150401 |