CN104547250A - Traditional Chinese medicine composition for inhibiting cancer cell proliferation and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for inhibiting cancer cell proliferation and preparation method of traditional Chinese medicine composition Download PDFInfo
- Publication number
- CN104547250A CN104547250A CN201510011404.5A CN201510011404A CN104547250A CN 104547250 A CN104547250 A CN 104547250A CN 201510011404 A CN201510011404 A CN 201510011404A CN 104547250 A CN104547250 A CN 104547250A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- medicine composition
- herba
- minute
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/648—Myriapods, e.g. centipedes or millipedes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/84—Valerianaceae (Valerian family), e.g. valerian
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a traditional Chinese medicine composition for inhibiting cancer cell proliferation. The traditional Chinese medicine composition is prepared from the following main raw materials in parts by weight: 3-9 parts of centipede, 15-30 parts of tender catchweed bedstraw herb, 10-30 parts of herb or fruit of little groundcherry, 3-9 parts of golden larch bark, 3-10 parts of radix angelicae pubescentis, 15-30 parts of medical stone, 15-30 parts of natural indigo, 10-20 parts of bitter orange, 10-20 parts of American ginseng, 5-9 parts of epimedium herb, 3-6 parts of radix przewalskii tanguticae, 3-15 parts of rhizome of broadleaf common valeriana, 15-40 parts of chicken's gizzard-membrane, 10-30 parts of barbed skullcap herb and 10-30 parts of milkvetch root. The traditional Chinese medicine composition has a significant effect of inhibiting cancer cell proliferation and has not only the effect of relieving cancer pain, but also the anti-cancer and anti-tumor effects. The traditional Chinese medicine composition disclosed by the invention is mainly prepared by selecting local common medicinal materials, the price is low, and the economic burden on a patient is relieved.
Description
Technical field
The invention discloses a kind of anticancer diffusion Chinese medicine composition, Chinese medicine composition of especially anticancer diffusion and preparation method thereof, the invention belongs to traditional Chinese medicine field.
Background technology
Cancer is the general designation of a large class malignant tumor.The feature of cancerous cell be unrestrictedly, hypertrophy without end, the nutrient substance in patient body is consumed in a large number; Cancerous cell discharges multiple toxin, makes human body produce series of symptoms; Cancerous cell also can be transferred to whole body growth and breeding everywhere, cause human body to be become thin, unable, anemia, inappetence, heating and serious organ function impaired etc.On the other side have benign tumor, benign tumor is then easily removed clean, generally do not shift, do not recur, extruding and blocking action are only had to organ, tissue, but cancer (malignant tumor) also can disorganize, organ 26S Proteasome Structure and Function, cause downright bad hemorrhage concurrent infection, patient is finally dead due to organ failure.Arrived today of science high speed development, we have reason to believe that cancer is not incurable disease.The medical experts being devoted to Natural medicine research study discovery: anion has challenging effect to anticancer transfer, importantly utilize natural factor anion to treat to body without any infringement, without any toxic and side effects to cancer patient.
The veil of the serious illness has been opened in numerous medical research and clinical trial: human body cell electronics is the source of ten thousand diseases by plunder, active oxygen (free radical ROS) is a kind of material (unsaturated electron species) lacking electronics, electronics is fought for everywhere after entering human body, if seize the electronics of cell protein molecule, make protein connect side chain generation alkylation, formed distortion molecule and carcinogenic.This distortion molecule lacks electronics due to oneself, removes the electronics capturing neighboring molecule again, make again neighboring molecule also occur distortion and carcinogenic.Like this, vicious cycle will form the protein molecular of a large amount of distortion, when the protein molecular breeding of these distortion copies, and gene mutation.Form a large amount of cancerous cell, finally occur cancer.The dangerous exception of the cancer state of an illness, the breeding of cancerous cell, the speed of diffusion are exceedingly fast, and modern medicine is usually felt simply helpless.Witnessing cancer to wreak havoc, will the mankind await one's doom? actually this is not so.As the saying goes: one thing conquers another.Clinical trial proves: after human body obtains negative oxygen ion, has unnecessary electronics because anion is electronegative, can provide a large amount of electronics, thus blocks vicious cycle, and cancerous cell just can prevent or suppressed.In addition, negative oxygen ion by regulate the acid base imbalance in the body that causes because of malignant tumor and redox state unbalance, maintain the stability of internal milieu, promote normal cellular metabolism, alleviate, eliminate the bad negative interaction of chemotherapy, the treatment of patient is highly profitable.Be exactly that negative oxygen ion not only can effectively anticancer transfer more can the generation of fundamentally prophylaxis of cancer in brief, final hit cancer is bare-knuckled.Physician points out that cancer is because being: body causes the result of health normal cell generation canceration under the effect of environmental pollution, chemical contamination (chemical toxicant), ionizing radiation, free radical toxin, microorganism (antibacterial, fungus, virus etc.) and the various carcinogen of metabolic toxicities, inherited character, endocrine imbalance, immunologic function disorder etc. thereof, carcinogenic factor, often shows as: the cellular abnormality hypertrophy of local organization and the local lump formed.Cancer is that organism normal cell is in many reasons, multistage and a caused large class disease of repeatedly suddenling change.
Clinical manifestation: because the happening part of various cancer is different, pathomorphism is different, and developmental stage is different, therefore can produce various clinical manifestation.But the early stage often symptom of cancer is little, to be developedly after certain phase, just gradually show series of symptoms and sign.Generally the clinical manifestation of cancer is divided into topical manifestations and systemic symptoms two aspects.One, the topical manifestations of cancer mainly contains: 1, lump: cancerous cell malignant proliferation is formed, and available hands touches at body surface or deep.The cancer of thyroid, the parotid gland or mammary gland can touch in subcutaneous comparatively superficial part position.Neoplasm metastasis, to lymph node, can cause lymphadenectasis, some superficial lymph node, as cervical lymph node and axillary fossa lymph easily touch.As in the gastric cancer, cancer of pancreas etc. of health compared with position, deep, then firmly to press and just can contact.The tumor growth that malignant tumor comprises cancer is rapid, and air spots is sliding, not easily promotes; Benign tumor is general surface smoothing then, as egg easy slip the same as table tennis.2, pain: occur pain often point out cancer to enter in, late period.Start mostly to be dull pain or dull pain, night is obvious.Increase the weight of gradually later, become and be difficult to stand, around the clock.General analgesic is inoperative.Pain is generally that cancerous cell invades neural causing.3, ulcer: because the cancerous tissue growth of some body surface cancer is fast, nutrition supply is not enough, when occurring that tissue necrosis is formed.As some breast carcinoma can occur volcanic crater sample or cauliflower-like ulcer at breast place, secrete courageous and upright secretions, can foul smelling taste during accompanying infection.In addition, stomach, colon cancer also can form ulcer, generally only have and just be can be observed by gastroscope, colonoscope.4, hemorrhage: cancerous tissue infringement blood vessel or cancerous tissue thin vessels break and produce.As anticancer diffusion patient can spit blood, sputum mixed with blood; Stomach, colon, the esophageal carcinoma then can be had blood in stool.5, block: cancerous tissue ramp and blocking of causing.When the raw dyspnea that region of obstruction at respiratory tract is; The esophageal carcinoma blocks esophagus then dysphagia; The cancer at biliary tract position can block common bile duct and SHENGHUANG subcutaneous ulcer; Bladder cancer urethral obstruction and occur dysuria etc.In a word, the position of blocking because of cancer is different and occur different symptoms.6, other: intracranial tumor can cause the multiple neurological symptom such as visual disorder (compressing optic nerve), facial paralysis (pressure surface neural); Bone tumor invades skeleton can cause fracture; Hepatocarcinoma causes plasma albumin reduce and cause ascites etc.
Summary of the invention
Along with the development of Chinese Chinese medicine, spread at treatment and anticancer, people gradually appreciate Chinese medicine anticancer diffusion disease therapeutic process and have no side effect, patient bears painful little, and the advantage that cost is saved relatively, for the present situation of existing western medical treatment cancer, an object of the present invention is the Chinese medicine composition providing a kind of Therapeutic cancer, there is feature easy to operate, evident in efficacy, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A Chinese medicine composition for anticancer diffusion, takes off the primary raw material stating weight proportion and is prepared from: Scolopendra 3-9 part, Herba Galii Teneri 15-30 part, Herba seu Fructus Physalis Minimae 10-30 part, Cortex Pseudolaricis 3-9 part, Radix Angelicae Pubescentis 3-10 part, Maifanitum 15-30 part, Indigo Naturalis 15-30 part, Fructus Aurantii 10-20 part, Radix Panacis Quinquefolii 10-20 part, Herba Epimedii 5-9 part, Tangut Przewalskia 3-6 part, Rhizoma valerianae latifoliae 3-15 part, Endothelium Corneum Gigeriae Galli 15-40 part, Herba Scutellariae Barbatae 10-30 part, Radix Astragali 10-30 part.
A Chinese medicine composition for anticancer diffusion, preferred scheme, takes off the primary raw material stating weight proportion and is prepared from: Scolopendra 5-9 part, Herba Galii Teneri 16-25 part, Herba seu Fructus Physalis Minimae 15-25 part, Cortex Pseudolaricis 4-8 part, Radix Angelicae Pubescentis 4-8 part, Maifanitum 18-28 part, Indigo Naturalis 18-25 part, Fructus Aurantii 12-18 part, Radix Panacis Quinquefolii 14-18 part, Herba Epimedii 6-8 part, Tangut Przewalskia 3.5-5 part, Rhizoma valerianae latifoliae 6-14 part, Endothelium Corneum Gigeriae Galli 20-38 part, Herba Scutellariae Barbatae 15-28 part, Radix Astragali 12-28 part.
A Chinese medicine composition for anticancer diffusion, better preferred scheme, takes off the primary raw material stating weight proportion and is prepared from: Scolopendra 8 parts, Herba Galii Teneri 20 parts, Herba seu Fructus Physalis Minimae 20 parts, Cortex Pseudolaricis 6 parts, Radix Angelicae Pubescentis 5 parts, Maifanitum 20 parts, Indigo Naturalis 20 parts, Fructus Aurantii 15 parts, Radix Panacis Quinquefolii 15 parts, Herba Epimedii 7 parts, Tangut Przewalskia 4 parts, Rhizoma valerianae latifoliae 12 parts, Endothelium Corneum Gigeriae Galli 30 parts, Herba Scutellariae Barbatae 25 parts, the Radix Astragali 15 parts.
Another object of the present invention is just to provide the preparation method of above-mentioned anticancer diffusion.
A preparation method for the Chinese medicine composition of anticancer diffusion, is prepared from primarily of following step:
1. be placed in clean container by Sal, add the hot water of 70-90 DEG C, instill Oleum sesami after 20-40 minute, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 80-120 mesh sieve;
2. Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Cortex Pseudolaricis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 3-6 hour, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 6-12 minute, grind to form smalls with large ferrum spoon, cross 100-140 mesh sieve;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 5-15 minute, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Radix Panacis Quinquefolii, Herba Epimedii, Tangut Przewalskia, Rhizoma valerianae latifoliae, Herba Scutellariae Barbatae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoct 50-70 minute, twice filtrate merges, and leaves standstill 3-5 hour, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 30-50 minute, obtain drying object, drying object is dry at 70-90 DEG C, both obtained according to every part of 10g subpackage.
The preparation method of above-mentioned Chinese medicine composition, 1. step adds the hot water of 75-85 DEG C, instills Oleum sesami (preferred, to add the hot water of 80 DEG C, instill Oleum sesami after 30 minutes) after 25-35 minute.
The preparation method of above-mentioned Chinese medicine composition, 2. step sprays evenly with the yellow wine burning heat, stewing 4-5 hour (preferred, spray evenly with the yellow wine burning heat, stewing 4.5 hours).
The preparation method of above-mentioned Chinese medicine composition, 2. the Chinese crude drug cooked is placed in rapidly in pot by step, parch 8-10 minute (preferred, to be placed in rapidly in pot by the Chinese crude drug cooked, parch 9 minutes).
The preparation method of above-mentioned Chinese medicine composition, 3. the filament cut is placed on and wipes on oily iron plate by step, dries 8-13 minute (preferred, to be placed on by the filament cut and to wipe on oily iron plate, dry 10 minutes).
The preparation method of above-mentioned Chinese medicine composition, step 4. twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoct 55-65 minute (preferred, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 60 minutes).
The preparation method of above-mentioned Chinese medicine composition, 5. thick paste is dried 35-45 minute by step, obtains drying object, by dry at 75-85 DEG C for drying object (preferred, thick paste to be dried 40 minutes, obtain drying object, by drying object drying at 80 DEG C).
This Chinese medicine composition is remarkable to anticancer diffusion effect, not only has effect of only cancer pain, also has anticancer antineoplastic action.The local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The pharmacological effect of each crude drug is respectively:
Scolopendra: Scolopendra is medicinal herbs most in use, warm in nature, acrid in the mouth is poisonous.There is the function of endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, apoplexy facial hemiparalysis, hemiplegia, tetanus disease, rheumatoid arthritis stubborn, skin infection, scrofula, venom.
Herba Galii Teneri: have another name called saw grass, draw rattan, fly upward rattan, the herb of taste Rubiaceae clivers Herba Galii Teneri or thick Ye Lala rattan.The property of medicine: herb is very thin, easily broken, the grayish green or green and brown color in surface, feeble QI, acrid in the mouth, bitter in the mouth, cold nature.Composition: Herba Galii Teneri aerial parts is containing alkaloid, and fruit contains Fructus Hordei Germinatus amine, jaligonic acid etc.; Thick Ye Lala rattan aerial parts contains asperuloside, vitamin C.Find according to modern pharmacological research, this medical instrument has antibacterial, anticancer, heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome, reducing swelling and alleviating pain effect, for swollen ulcer drug, and appendicitis, cold, fever, hematuria etc.
Herba seu Fructus Physalis Minimae: having another name called husky lantern, sky bubble fruit, the female pearl of king, is herb or the fruit of the little Calyx seu fructus physalis of Solanaceae monkey flower.The property of medicine: bitter in the mouth, cool in nature.Composition: herb examines little physalein etc. containing physagulin, epoxyphysagulin, Wei, containing Palmic acid, stearic acid, oleic acid etc. in seed oil.Find according to modern pharmacological research, this medical instrument has antiinflammatory, anticancer, clearing away heat-damp and promoting diuresis, goes to cough effect of only expectorant, hard masses softening and resolving, for jaundice due to damp-heat, and dysuria, chronic cough and asthma, eczema.
Cortex Pseudolaricis: have another name called arhat Cortex Pini Massonianae, wattle skin, pseudolaricis,cortex is root bark and the near root bark of Pinaceae Pseudolarix plant golden larch.The property of medicine: root bark is irregular strip, distortion and slightly rolling up, not of uniform size, matter is tough, feeble QI, acrid in the mouth, hardship, warm in nature.Composition: root bark contains pseudolaric acid B, betulic acid, myricetin, amaron alcohol A and B etc.Find according to modern pharmacological research, this medical instrument has effect of antifungal, anticancer, expelling wind and removing dampness, killing parasites for relieving itching, for eczema, and neurodermatitis.
Radix Angelicae Pubescentis: be the root of the heavy tooth Radix Angelicae Sinensis of Umbelliferae archangel.Composition: containing coumarin kind compound, volatile oil, acetas, angelol, thymol.Pharmacology: play a very important role to cardiovascular system, has the effect of blood pressure lowering, can promote hematoblastic gathering, have good analgesia and antiinflammatory action.There is anti-light quick effect, have significant curative effect to opposing tumor, anti-inflammation is also played a very important role.The property of medicine: bitter, tepor, pungent.Return kidney, urinary bladder channel.Function cures mainly: expelling wind and dampness, dispersing cold for relieving pain.
Maifanitum: base is former: be Acid-intermediate igneous rock rocks beschtauite.Composition: Maifanitum main component has silicon dioxide, aluminium oxide, ferrum oxide, ferrous oxide, magnesium oxide, calcium oxide, sodium oxide, potassium oxide, titanium dioxide, phosphorus pentoxide, manganese oxide, carbon dioxide, and the trace element such as fluorine, sulfur, strontium, barium, copper, zinc.The property of medicine: " detailed outline ": " sweet, temperature, nontoxic." function cures mainly: removing toxic substances and promoting granulation, damp eliminating spleen invigorating.Cure mainly carbuncle carbuncle on the back, acne, eczema, beriberi, miliaria, finger is chapped, chloasma, toothache, oral ulcer, rheumatic arthralgia, lumbago and backache, chronic hepatitis, gastritis, dysentery, diabetes, neurasthenia, wound is red and swollen, hypertension, senile sclerosis of blood vessels, tumor, lithangiuria.Generally make health product.
Indigo Naturalis: have another name called Concha Meretricis Seu Cyclinae powder, indigo-blue flower, for the leaf of Acanthaceae Acanthaceous indigo platymiscium Acanthaceous indigo, Polygonaceae arsesmart polygonum tinctorium ait., pulse family anil Folium et Caulis Indigoferae Tinctoriae, Cruciferae Isatis indigotica Fort. platymiscium Isatis indigotica Fort. or stem and leaf are through processing obtained dried powder or agglomerate.The property of medicine: this product is navy blue powder, body is light, and easily fly upward, micro-have careless stink smell, salty in the mouth, cold in nature.Composition: its main component has indirubin, indigo.Find according to modern pharmacological research, this medical instrument has effect of antitumor, anti-inflammatory and antalgic, antiulcer, antibacterial, clearing away heat and cooling blood, removing toxic substances, and for the malicious macule of temperature, laryngopharynx swelling and pain, spits blood, epistaxis, the symptoms such as spitting of blood.
Fructus Aurantii: dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.
Radix Panacis Quinquefolii: boosting qi and nourishing yin, clearing away heat and promoting production of body fluid.Lose for deficiency of vital energy the moon, interior-heat, cough with asthma expectorant blood, deficiency-heat is tired of tired, quenches one's thirst, and dry mouth larynx is done.Lung benefiting is cloudy, clear asthenic fire, promoting the production of body fluid to quench thirst.Control deficiency of the lung chronic cough, lose blood, dry throat and mouth, deficiency-heat is tired of tired.
Herba Epimedii: kidney invigorating and YANG supporting, expelling wind and removing dampness.Control sexual impotence erectile problem, hemiplegia is unsuccessful, dribbling urination, and muscles and bones contraction is anxious, and cough, optic atrohic blindness after being ill, toothache caused by fire of deficiency type, hemiplegia, weakness of the waist and knees, rheumatic arthralgia, extremity are meciless.
Tangut Przewalskia: base is former: be root and the seed of Solanaceae Tangut Przewalskia platymiscium Tangut Przewalskia.Composition: containing tropine in root, Cuscohygrine, Anisodamine, i.e. left-handed 6-hydroxyl hyoscyamine, hyoscyamine, apoatropine, Anisodine, scopolamine etc.The property of medicine: bitter, acrid, cold, poisonous.Function cures mainly: " the sweet peaceful blue or green Chinese herbal medicine choosing in Shan ": " analgesia detumescence, cures mainly digestive tract spasmic pain, sore, carcinoma and dermatosis.
Rhizoma valerianae latifoliae: be the rhizome of Valerianaceae platymiscium Rhizoma valerianae latifoliae.Composition: root welding technology, mainly containing volatile ingredient, also contains caffeic acid.Pharmacology: inhibited to nervus centralis, has antineoplastic action.The property of medicine: pungent, micro-hardship, temperature.Function cures mainly: regulating the flow of Qi and the middle Jiao, dispelling cold and removing dampness, promoting blood circulation and detumescence.
Endothelium Corneum Gigeriae Galli: sweet is flat.Return spleen, stomach, small intestinal, urinary bladder channel, promoting digestion and invigorating the stomach is aid digestion, arresting seminal emission.Can gastric secretion be promoted, improve gastric acidity and eupepsy, stomach motor function is obviously strengthened, rapid gastric emptying.Arresting seminal emission.Appropriate digested bad, shallow complexion, do not think the condition subject such as Na Gu, infantile malnutrition, emaciated physique, enlarged abdomen abdominal distention, weakness of the spleen and stomach, food stagnation distension, tuberculosis of intestine, bone tuberculosis and eat.
Herba Scutellariae Barbatae: heat-clearing and toxic substances removing, blood stasis dispelling diuresis.For furuncle swelling toxin, laryngopharynx swelling and pain, falls and flutters the pain of injury, edema, jaundice, snake bite and insect sting.
The Radix Astragali: the Radix Astragali has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.Jishengshenqiwan albuminuria can be eliminated, strengthen myocardial contraction, regulate blood sugar content.The Radix Astragali can not only coronary artery dilator, improves blood supply of cardiac muscle, improves immunologic function, and can the process of delaying cell aging.
Chinese medicine composition of the present invention debates the principle of disease treatment based on Chinese medicine.Prepared Chinese medicine composition is divided into two, a for wash open as Orally-administered decoction medicine with hot water, another part Ovum Gallus domesticus album is mixed thoroughly as external is applied ointment or plaster, inside and outside treat simultaneously, treatment is more comprehensive, and affected area administration is more rapid, lasting medicine, take into account inside and outside belonging to, the anticancer diffusion prescription for the treatment of both the principal and secondary aspects of a disease.Fabulous therapeutical effect is had, for thin and weak health has fabulous opsonic action because of long-term chemicotherapy to anticancer diffusion.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
The Chinese medicine composition of embodiment 1 one kinds of anticancer diffusions, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Scolopendra 3 parts, Herba Galii Teneri 15 parts, Herba seu Fructus Physalis Minimae 10 parts, Cortex Pseudolaricis 3 parts, Radix Angelicae Pubescentis 3 parts, Maifanitum 15 parts, Indigo Naturalis 15 parts, Fructus Aurantii 10 parts, Radix Panacis Quinquefolii 10 parts, Herba Epimedii 5 parts, Tangut Przewalskia 3 parts, Rhizoma valerianae latifoliae 3 parts, Endothelium Corneum Gigeriae Galli 15 parts, Herba Scutellariae Barbatae 10 parts, the Radix Astragali 10 parts.
The Chinese medicine composition of anticancer diffusion, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 70 DEG C, instill Oleum sesami after 20 minutes, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 80 mesh sieves;
2. Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Cortex Pseudolaricis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 3 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 6 minutes, grind to form smalls with large ferrum spoon, cross 100 mesh sieves;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 5 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Radix Panacis Quinquefolii, Herba Epimedii, Tangut Przewalskia, Rhizoma valerianae latifoliae, Herba Scutellariae Barbatae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 50 minutes, twice filtrate merges, and leaves standstill 3 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 30 minutes, obtain drying object, drying object is dry at 70 DEG C, both obtained according to every part of 10g subpackage.
Model case one: Liu XX, female, 45 years old, Jinan City, Shandong Province personage.Symptom:: difficulty of swallowing of eating, weight loss, intermittent pharyngeal pain and hoarseness, with serious vomiting, go hospital diagnosis to be advanced esophageal cancer.Be thought of as the multiple muscle transfer of whole body, do not have appetite, lean body mass is weak.Treatment is stopped because standing and hold untoward reaction and high expense that can't stand chemotherapy.
Use and take embodiment 1 resulting composition, compositions is divided into two, a for wash open as Orally-administered decoction medicine with hot water, 2 times on the one, the morning, noon and afternoon take after meal half an hour, and another part is mixed thoroughly with Ovum Gallus domesticus album and is applied in the tsusanli acupoint (two), once a day, use traditional Chinese medicine composition for treating of the present invention 5 days, pain symptom alleviates, and appetite is recovered to some extent; Use traditional Chinese medicine composition for treating of the present invention 4 months, go to hospital to check cancerous cell and substantially do not spread; Use traditional Chinese medicine composition for treating of the present invention 7 months, cancerous cell basic controlling there is not diffusing phenomenon.
The Chinese medicine composition of embodiment 2 one kinds of anticancer diffusions, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Scolopendra 9 parts, Herba Galii Teneri 30 parts, Herba seu Fructus Physalis Minimae 30 parts, Cortex Pseudolaricis 9 parts, Radix Angelicae Pubescentis 10 parts, Maifanitum 30 parts, Indigo Naturalis 30 parts, Fructus Aurantii 20 parts, Radix Panacis Quinquefolii 20 parts, Herba Epimedii 9 parts, Tangut Przewalskia 6 parts, Rhizoma valerianae latifoliae 15 parts, Endothelium Corneum Gigeriae Galli 40 parts, Herba Scutellariae Barbatae 30 parts, the Radix Astragali 30 parts.
The Chinese medicine composition of anticancer diffusion, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 90 DEG C, instill Oleum sesami after 40 minutes, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 120 mesh sieves;
2. Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Cortex Pseudolaricis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 6 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 12 minutes, grind to form smalls with large ferrum spoon, cross 140 mesh sieves;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 15 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Radix Panacis Quinquefolii, Herba Epimedii, Tangut Przewalskia, Rhizoma valerianae latifoliae, Herba Scutellariae Barbatae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 70 minutes, twice filtrate merges, and leaves standstill 5 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 50 minutes, obtain drying object, drying object is dry at 90 DEG C, both obtained according to every part of 10g subpackage.
Model case two: Lee xx, man, 39 years old, Meng Jia village, Jin Zhuan town, Sishui County, Jining City in Shandong Province.Symptom: the situation occurring cough uncomfortable in chest, left breast dull pain, patient was busy at that time, often went on business and did not also take notice of very much, think indisposition, after 1 month, chest pain does not only slow down, and aggravates on the contrary, once cough is spat, sputum mixed with blood, and patient's self-induction is far from good, remove examination in hospital, be diagnosed as advanced lung cancer through hospital of Jining City, lymph metastasis, chronic cough, the excessive phlegm band blood streak, hydrothorax, chemotherapy is after 1 month, and health holds really be can't stand, hear of Chinese medicine composition curative effect of the present invention fine.
Use and take embodiment 2 resulting composition, compositions is divided into two, a for wash open as Orally-administered decoction medicine with hot water, 2 times on the one, the morning, noon and afternoon take after meal half an hour, another part is mixed thoroughly with Ovum Gallus domesticus album and is applied in the tsusanli acupoint (two), once a day, use traditional Chinese medicine composition for treating of the present invention 10 days, cough alleviates, pain symptom alleviates, and appetite is recovered to some extent; Use traditional Chinese medicine composition for treating of the present invention 5 months, go to hospital to check cancerous cell and substantially do not spread; Use traditional Chinese medicine composition for treating of the present invention 6 months, cancerous cell basic controlling there is not diffusing phenomenon.
The Chinese medicine composition of embodiment 3 one kinds of anticancer diffusions, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Scolopendra 5 parts, Herba Galii Teneri 16 parts, Herba seu Fructus Physalis Minimae 15 parts, Cortex Pseudolaricis 4 parts, Radix Angelicae Pubescentis 4 parts, Maifanitum 18 parts, Indigo Naturalis 18 parts, Fructus Aurantii 12 parts, Radix Panacis Quinquefolii 14 parts, Herba Epimedii 6 parts, Tangut Przewalskia 3.5 parts, Rhizoma valerianae latifoliae 6 parts, Endothelium Corneum Gigeriae Galli 20 parts, Herba Scutellariae Barbatae 15 parts, the Radix Astragali 12 parts.
The Chinese medicine composition of anticancer diffusion, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 75 DEG C, instill Oleum sesami after 25 minutes, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 90 mesh sieves;
2. Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Cortex Pseudolaricis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 4 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 6 minutes, grind to form smalls with large ferrum spoon, cross 110 mesh sieves;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 8 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Radix Panacis Quinquefolii, Herba Epimedii, Tangut Przewalskia, Rhizoma valerianae latifoliae, Herba Scutellariae Barbatae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 55 minutes, twice filtrate merges, and leaves standstill 3.5 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 35 minutes, obtain drying object, drying object is dry at 75 DEG C, both obtained according to every part of 10g subpackage.
Model case three: poplar xx, female, 50 years old, the Su Han village, Pingdu City Lan Di town, Shandong Province.Symptom: the regular dull pain of stomach, belch, vomiting, do not have appetite, and lean body mass is weak.Go to hospital to make a definite diagnosis to be gastric cancer mid-term, to do chemotherapy 2 months, stop treatment because standing and hold untoward reaction and high expense that can't stand chemotherapy, sick age: 6 months.Examine the time: in July, 2012.
Use and take embodiment 3 resulting composition, compositions is divided into two, a for wash open as Orally-administered decoction medicine with hot water, 2 times on the one, the morning, noon and afternoon take after meal half an hour, and another part is mixed thoroughly with Ovum Gallus domesticus album and is applied in the tsusanli acupoint (two), WEIYU acupoint, once a day, use traditional Chinese medicine composition for treating of the present invention 5 days, pain symptom alleviates, and appetite is recovered to some extent; Use traditional Chinese medicine composition for treating of the present invention 4 months, go to hospital to check cancerous cell and substantially do not spread; Use traditional Chinese medicine composition for treating of the present invention 5 months, cancerous cell basic controlling there is not diffusing phenomenon.
The Chinese medicine composition of embodiment 4 one kinds of anticancer diffusions, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Scolopendra 9 parts, Herba Galii Teneri 25 parts, Herba seu Fructus Physalis Minimae 25 parts, Cortex Pseudolaricis 8 parts, Radix Angelicae Pubescentis 8 parts, Maifanitum 28 parts, Indigo Naturalis 25 parts, Fructus Aurantii 18 parts, Radix Panacis Quinquefolii 18 parts, Herba Epimedii 8 parts, Tangut Przewalskia 5 parts, Rhizoma valerianae latifoliae 14 parts, Endothelium Corneum Gigeriae Galli 38 parts, Herba Scutellariae Barbatae 28 parts, the Radix Astragali 28 parts.
The Chinese medicine composition of anticancer diffusion, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 85 DEG C, instill Oleum sesami after 35 minutes, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 110 mesh sieves;
2. Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Cortex Pseudolaricis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 5 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 10 minutes, grind to form smalls with large ferrum spoon, cross 130 mesh sieves;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 13 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Radix Panacis Quinquefolii, Herba Epimedii, Tangut Przewalskia, Rhizoma valerianae latifoliae, Herba Scutellariae Barbatae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 65 minutes, twice filtrate merges, and leaves standstill 4.5 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 45 minutes, obtain drying object, drying object is dry at 85 DEG C, both obtained according to every part of 10g subpackage.
Model case four: field xx, man, 44 years old, people from Jiyang County, Jinan City, Shandong Province.Symptom: in November, 2010, because hepatic region severe pain is gone to a doctor, checks and finds that liver has a tumor 11x10cm.December CT on the 31st checks tumor and increases to 13x13cm, and various symptom increases the weight of day by day, is unable to leave the bed, and is diagnosed as advanced liver cancer.Doctor allows patient carry out chemotherapy, and in the process of chemotherapy, leukocyte, number of platelets decline serious, with stomachache, so patient's refusal accepts chemotherapy, the doctor advised present composition again.
Use and take embodiment 4 resulting composition, compositions is divided into two, a for wash open as Orally-administered decoction medicine with hot water, 2 times on the one, morning, noon and afternoon take after meal half an hour, another part is mixed thoroughly with Ovum Gallus domesticus album and is applied in the tsusanli acupoint (two), once a day, uses traditional Chinese medicine composition for treating of the present invention 15 days, pain symptom alleviates, appetite is recovered to some extent, and muscle power obviously increases, and oneself can get up and arrive outdoor stroll; Use traditional Chinese medicine composition for treating of the present invention 3 months, go to hospital to check cancerous cell and substantially do not spread; Use traditional Chinese medicine composition for treating of the present invention 5 months, cancerous cell does not have change substantially, and body weight increases, and quality of life, mood was more optimistic than originally than there being very large change during western medical treatment, had had new hope to life, in continuing at present to take.
The Chinese medicine composition of embodiment 5 one kinds of anticancer diffusions, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Scolopendra 8 parts, Herba Galii Teneri 20 parts, Herba seu Fructus Physalis Minimae 20 parts, Cortex Pseudolaricis 6 parts, Radix Angelicae Pubescentis 5 parts, Maifanitum 20 parts, Indigo Naturalis 20 parts, Fructus Aurantii 15 parts, Radix Panacis Quinquefolii 15 parts, Herba Epimedii 7 parts, Tangut Przewalskia 4 parts, Rhizoma valerianae latifoliae 12 parts, Endothelium Corneum Gigeriae Galli 30 parts, Herba Scutellariae Barbatae 25 parts, the Radix Astragali 15 parts.
The Chinese medicine composition of anticancer diffusion, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 80 DEG C, instill Oleum sesami after 30 minutes, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 100 mesh sieves;
2. Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Cortex Pseudolaricis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 4.5 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 9 minutes, grind to form smalls with large ferrum spoon, cross 120 mesh sieves;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 10 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Radix Panacis Quinquefolii, Herba Epimedii, Tangut Przewalskia, Rhizoma valerianae latifoliae, Herba Scutellariae Barbatae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 60 minutes, twice filtrate merges, and leaves standstill 4 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 40 minutes, obtain drying object, drying object is dry at 80 DEG C, both obtained according to every part of 10g subpackage.
Experimental example: clinical data: 1, physical data: be diagnosed as patient with advanced cancer through histopathology and cytolgical examination, the age is between 25-70; Important organ function of organization is normal.The patient meeting this research inclusion criteria is 400 examples.
2, diagnostic criteria: Western medicine diagnose standard: specified standard in " Chinese common cancer diagnosis and treatment specification " that diagnostic criteria adopts Department of Medical Administration of Ministry of Health of the People's Republic of China to write.Tcm diagnosis standard: formulating with reference to Ministry of Public Health " new Chinese medicine guideline of clinical investigations " (2002 editions), distinguishing as accumulateing disease in ecchymosis: pain, lump, can with low grade fever, purplish tongue or have petechia, ecchymosis, yellow and thin fur, hesitant pulse or stringy and thready pulse.
3, Therapeutic Method: adopt Chinese medicine composition of the present invention, compositions is divided into two, a for wash open as Orally-administered decoction medicine with hot water, 2 times on the one, morning, noon and afternoon take after meal half an hour, and another part is mixed thoroughly with Ovum Gallus domesticus album and is applied in the tsusanli acupoint (two), once a day.
4, criterion of therapeutical effect: effective: cancerous cell is suppressed is invalid: malaise symptoms is all unchanged.In order to verify the effect of Chinese medicine composition of the present invention, We conducted the experiment (embodiment 5) of medicine, and accurately statistics and mathematical analysis having been carried out to data.
Specific experiment result is as following table:
Table 1:
Table 2:
Prove through clinical trial, use Chinese medicine composition of the present invention compared with the means of western medical treatment cancer, control recurrence rate after healing low, treatment means is more comprehensive thoroughly, have no side effect between the operating period, while anticancer diffusion, can alleviate and spread by anticancer the symptom such as pain, heating, inappetence brought.Prove through clinical trial, Chinese drugs agentia effective percentage of the present invention is 99%, good therapeutical effect is all had for early stage and anticancer diffusion in late period, for anticancer diffusion in late period patient, use Chinese medicine composition of the present invention, while effectively controlling cancerous cell high speed diffusion, the quality of life of residue life can be made to improve, increase the confidence for future life.Therefore Chinese medicine composition of the present invention is the medicine of a kind of anticancer safely and effectively diffusion.
Claims (10)
1. a Chinese medicine composition for anticancer diffusion, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Scolopendra 3-9 part, Herba Galii Teneri 15-30 part, Herba seu Fructus Physalis Minimae 10-30 part, Cortex Pseudolaricis 3-9 part, Radix Angelicae Pubescentis 3-10 part, Maifanitum 15-30 part, Indigo Naturalis 15-30 part, Fructus Aurantii 10-20 part, Radix Panacis Quinquefolii 10-20 part, Herba Epimedii 5-9 part, Tangut Przewalskia 3-6 part, Rhizoma valerianae latifoliae 3-15 part, Endothelium Corneum Gigeriae Galli 15-40 part, Herba Scutellariae Barbatae 10-30 part, Radix Astragali 10-30 part.
2. the Chinese medicine composition of anticancer diffusion according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Scolopendra 5-9 part, Herba Galii Teneri 16-25 part, Herba seu Fructus Physalis Minimae 15-25 part, Cortex Pseudolaricis 4-8 part, Radix Angelicae Pubescentis 4-8 part, Maifanitum 18-28 part, Indigo Naturalis 18-25 part, Fructus Aurantii 12-18 part, Radix Panacis Quinquefolii 14-18 part, Herba Epimedii 6-8 part, Tangut Przewalskia 3.5-5 part, Rhizoma valerianae latifoliae 6-14 part, Endothelium Corneum Gigeriae Galli 20-38 part, Herba Scutellariae Barbatae 15-28 part, Radix Astragali 12-28 part.
3. the Chinese medicine composition of anticancer diffusion according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Scolopendra 8 parts, Herba Galii Teneri 20 parts, Herba seu Fructus Physalis Minimae 20 parts, Cortex Pseudolaricis 6 parts, Radix Angelicae Pubescentis 5 parts, Maifanitum 20 parts, Indigo Naturalis 20 parts, Fructus Aurantii 15 parts, Radix Panacis Quinquefolii 15 parts, Herba Epimedii 7 parts, Tangut Przewalskia 4 parts, Rhizoma valerianae latifoliae 12 parts, Endothelium Corneum Gigeriae Galli 30 parts, Herba Scutellariae Barbatae 25 parts, the Radix Astragali 15 parts.
4. the preparation method of the Chinese medicine composition of the anticancer diffusion according to any one of claim 1-3, is characterized in that: step is prepared as follows:
1. be placed in clean container by Sal, add the hot water of 70-90 DEG C, instill Oleum sesami after 20-40 minute, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 80-120 mesh sieve;
2. Herba Galii Teneri, Herba seu Fructus Physalis Minimae and Cortex Pseudolaricis are cleaned, drain away the water, be cut into silk, together be placed in marmite with Scolopendra and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 3-6 hour, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 6-12 minute, grind to form smalls with large ferrum spoon, cross 100-140 mesh sieve;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 5-15 minute, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Radix Panacis Quinquefolii, Herba Epimedii, Tangut Przewalskia, Rhizoma valerianae latifoliae, Herba Scutellariae Barbatae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoct 50-70 minute, twice filtrate merges, and leaves standstill 3-5 hour, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 30-50 minute, obtain drying object, drying object is dry at 70-90 DEG C, both obtained according to every part of 10g subpackage.
5. the preparation method of Chinese medicine composition according to claim 4, is characterized in that: 1. step adds the hot water of 75-85 DEG C, soaks after 25-35 minute and instills Oleum sesami (preferred, to add the hot water of 80 DEG C, soak and instill Oleum sesami after 30 minutes).
6. the preparation method of Chinese medicine composition according to claim 4, is characterized in that: 2. step sprays evenly with the yellow wine burning heat, stewing 4-5 hour (preferred, spray evenly with the yellow wine burning heat, stewing 4.5 hours).
7. the preparation method of Chinese medicine composition according to claim 4, is characterized in that: 2. the Chinese crude drug cooked is placed in rapidly in pot by step, parch 8-10 minute (preferred, to be placed in rapidly in pot by the Chinese crude drug cooked, parch 9 minutes).
8. the preparation method of Chinese medicine composition according to claim 4, it is characterized in that: 3. the filament cut is placed on and wipes on oily iron plate by step, dry 8-13 minute (preferred, the filament cut to be placed on and to wipe on oily iron plate, dry 10 minutes).
9. the preparation method of Chinese medicine composition according to claim 4, it is characterized in that: step 4. twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoct 55-65 minute (preferred, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 60 minutes).
10. the preparation method of Chinese medicine composition according to claim 4, is characterized in that: 5. thick paste is dried 35-45 minute by step, obtains drying object, drying object is dry (preferred at 75-85 DEG C, thick paste is dried 40 minutes, obtain drying object, drying object is dry at 80 DEG C).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510011404.5A CN104547250A (en) | 2015-01-09 | 2015-01-09 | Traditional Chinese medicine composition for inhibiting cancer cell proliferation and preparation method of traditional Chinese medicine composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510011404.5A CN104547250A (en) | 2015-01-09 | 2015-01-09 | Traditional Chinese medicine composition for inhibiting cancer cell proliferation and preparation method of traditional Chinese medicine composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104547250A true CN104547250A (en) | 2015-04-29 |
Family
ID=53065021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510011404.5A Pending CN104547250A (en) | 2015-01-09 | 2015-01-09 | Traditional Chinese medicine composition for inhibiting cancer cell proliferation and preparation method of traditional Chinese medicine composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104547250A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031389A (en) * | 2015-09-16 | 2015-11-11 | 张翠茹 | Traditional Chinese medicine tablet for restraining malignant tumor breeding in cooperation with radiotherapy and preparing method of traditional Chinese medicine tablet |
| CN105106712A (en) * | 2015-09-17 | 2015-12-02 | 王守花 | Nutritional porridge capable of helping postoperative recovery of cancer patient and preparation method thereof |
| GB2557741B (en) * | 2015-05-20 | 2020-03-04 | Golden Health Guangdong Biotechnology Co Ltd | Icariside compound, preperation method thereof, and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102671130A (en) * | 2012-05-11 | 2012-09-19 | 胥科辉 | Anti-tumor traditional Chinese medicine |
| CN104127798A (en) * | 2013-05-02 | 2014-11-05 | 河北以岭医药研究院有限公司 | Application of traditional Chinese medicine composition in preparation of medicine used for inhibiting metastasis of cancer cells to peritoneum |
| CN104225395A (en) * | 2013-07-27 | 2014-12-24 | 郭香荣 | Tumor-resistant traditional Chinese medicine and preparation method |
-
2015
- 2015-01-09 CN CN201510011404.5A patent/CN104547250A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102671130A (en) * | 2012-05-11 | 2012-09-19 | 胥科辉 | Anti-tumor traditional Chinese medicine |
| CN104127798A (en) * | 2013-05-02 | 2014-11-05 | 河北以岭医药研究院有限公司 | Application of traditional Chinese medicine composition in preparation of medicine used for inhibiting metastasis of cancer cells to peritoneum |
| CN104225395A (en) * | 2013-07-27 | 2014-12-24 | 郭香荣 | Tumor-resistant traditional Chinese medicine and preparation method |
Non-Patent Citations (2)
| Title |
|---|
| 张宝南: "膈下逐瘀汤对晚期胰腺癌生存质量的影响", 《辽宁中医杂志》 * |
| 李永安等: "扶正解毒方联合化疗治疗晚期非小细胞肺癌40例", 《安徽中医学院学报》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2557741B (en) * | 2015-05-20 | 2020-03-04 | Golden Health Guangdong Biotechnology Co Ltd | Icariside compound, preperation method thereof, and application thereof |
| CN105031389A (en) * | 2015-09-16 | 2015-11-11 | 张翠茹 | Traditional Chinese medicine tablet for restraining malignant tumor breeding in cooperation with radiotherapy and preparing method of traditional Chinese medicine tablet |
| CN105106712A (en) * | 2015-09-17 | 2015-12-02 | 王守花 | Nutritional porridge capable of helping postoperative recovery of cancer patient and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104547250A (en) | Traditional Chinese medicine composition for inhibiting cancer cell proliferation and preparation method of traditional Chinese medicine composition | |
| CN104489518A (en) | Health-preserving porridge for treating neurasthenia and prepration method of health-preserving porridge | |
| CN103432269B (en) | Chinese medicinal preparation used for treating radiation enteritis | |
| CN108853346A (en) | A kind of external-applied ointment for treating cheilitis | |
| CN102205022B (en) | Chinese medicinal preparation for treating mycotic infection and preparation method thereof | |
| CN104147554A (en) | Traditional Chinese medicine for treating cancer pain | |
| CN107823293A (en) | Treat Yao nationality medicine external pulvis of canker sore and preparation method thereof | |
| CN113842443A (en) | Pharmaceutical composition for treating xerostomia after nasopharyngeal carcinoma radiotherapy | |
| CN105267696A (en) | Traditional Chinese medicine pill for treating kidney-yin-deficiency type chronic pyelonephritis and preparation method of traditional Chinese medicine pill for treating kidney-yin-deficiency type chronic pyelonephritis | |
| CN106110218B (en) | A kind of anti-cancer pain pain relieving plaster and preparation method thereof | |
| CN104474218A (en) | Stomach invigorating and food retention removing instant granules for slowing cancer cell spreading, and preparation method thereof | |
| CN104547701A (en) | Compound preparation for treatment of myocarditis and preparation method thereof | |
| CN104971316A (en) | Composition for treating esophageal cancer and preparation method thereof | |
| CN104435592A (en) | Traditional Chinese medicine for treating sudden sensor neural hearing loss and tinnitus and preparation method thereof | |
| CN104258224A (en) | Schisandra chinensis oral solution for treating lung-and-kidney yin-deficiency type chronic bronchitis and preparation method thereof | |
| CN104547749A (en) | Traditional Chinese medicine composition for treating lung cancer and preparation method of traditional Chinese medicine composition | |
| CN104189608B (en) | Traditional Chinese medicine preparation for recurrent oral ulcer and preparation method thereof | |
| CN104888172B (en) | Treat ginger green onion cough arresting and the application of allergic cough | |
| CN105031389A (en) | Traditional Chinese medicine tablet for restraining malignant tumor breeding in cooperation with radiotherapy and preparing method of traditional Chinese medicine tablet | |
| CN105663828A (en) | Medicine for treating postnatal depression and preparation method | |
| CN104971210A (en) | External lotion for treating tinea pedis and preparation method thereof | |
| CN104474161A (en) | Blood stasis-removing powder for treating esophageal cancer and preparation method of blood stasis-removing powder | |
| CN104491263A (en) | Medicine capable of promoting blood circulation to remove blood stasis for esophagus cancer and preparation method of medicine | |
| CN104740403A (en) | Medicine for treating blood-insufficiency and yin-deficiency recurrent oral ulceration and preparation method thereof | |
| CN104547464A (en) | Traditional Chinese medicine decoction for treating upper respiratory infection and preparation method of traditional Chinese medicine decoction |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150429 |
|
| RJ01 | Rejection of invention patent application after publication |