CN107823293A - Treat Yao nationality medicine external pulvis of canker sore and preparation method thereof - Google Patents
Treat Yao nationality medicine external pulvis of canker sore and preparation method thereof Download PDFInfo
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- CN107823293A CN107823293A CN201711002578.0A CN201711002578A CN107823293A CN 107823293 A CN107823293 A CN 107823293A CN 201711002578 A CN201711002578 A CN 201711002578A CN 107823293 A CN107823293 A CN 107823293A
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- canker sore
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- external pulvis
- yao nationality
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Abstract
The invention discloses a kind of Yao nationality medicine external pulvis for treating canker sore and preparation method thereof, it is made of the raw material including following compositions：The effect of hairy euphorbia, sour rattan root, goldenrod and blank sheet of paper fan, the raw material drying of said ratio pulverizes and sieves, is stirred, Yao nationality medicine traditional Chinese powder medicine is made, and this external pulvis is clearing heat and detoxicating, dissipate stasis of blood hemostasis, anti-inflammation, swelling and pain relieving.There is the effect of good to all kinds of canker sore patients, easy to operate, safety, few side effects, can guide drugs to illness station.
Description
Technical field
The present invention relates to a kind of Yao nationality medicine external pulvis and preparation method thereof, more particularly to the external powder for the treatment of canker sore
Agent and preparation method.
Background technology
Canker sore is commonly called as " aphtha ", is a kind of common ulcerative damages illness for betiding mucous membrane of mouth, is more common in
The positions such as lip inner side, tongue, tongue abdomen, cheek mucous membrane, vestibular ditch, soft palate, the mucous membrane at these positions lack keratinization layer or angling compared with
Difference.Tongue ulcer, which refers to, betides tongue, the canker sore of tongue belly position.Sharp ache when canker sore is broken out, local cusalgia are bright
Aobvious, severe patient can also influence diet, speak, and very big inconvenience is caused to daily life；When serious can concurrently halitosis, chronic pharyngitis,
The constitutional symptom such as constipation, headache, dizziness, nausea, weak, irritated, heating, enlargement of lymph nodes.
Canker sore is the result of many factors comprehensive function, it include local trauma, stress, food,
Medicine, malnutrition, hormonal readiness changes and vitamin or microelement deficiencies.Systemic disease, heredity, immune and microorganism
It may be played an important role in generation, development in canker sore.Such as lack trace element zinc, iron, lack folic acid, vitamin B12
And malnutrition etc., immunologic function, the possibility of increase canker sore morbidity can be reduced；Streptococcus sanguis and helicobacter pylori etc.
Bacterium is also in close relations with canker sore.Canker sore generally imply that body may have potential systemic disease, canker sore
With gastric ulcer, duodenal ulcer, ulcerative colitis, regional enteritis, hepatitis, female menstrual period, vitamin B complex malabsorption
Disease, vegetative nerve functional disturbance disease etc. are relevant.
The traditional Chinese medical science thinks this sick generation, and external cause is referred to and smoked and drink based on heat toxin mostly, excessively fed fried, barbecue,
Pungent food, cause heart spleen position, lung, stomach and liver and gall position the situation of accumulated heat occur, ultimately result in excessive internal heat, aphtha
The appearance of disease, this belongs to excess fire, and morbidity is quickly.Internal cause is mostly feelings will internal injury, eating and drinking without temperance, caused by chamber overstrain, general feelings
It is due to continuously to stay up late under condition, negative emotions are tired, and the fire of deficiency type caused by pressure is excessive etc., some are getting in years and body
Weaker patient, spleen and stomach function sustain damage, and cause middle burnt hinge normally to work, and upper and lower mechanism of qi can not connect,
Excessive fire in heart, this, which is also resulted in, there is aphtha, and this falls within the chronic diseases marked by deficiency of vital energy, and the morbidity of the fire of deficiency type is relatively slow.
We pass through literature search, it has been found that some Chinese medicine preparations on treating canker sore, such as：
1st, a kind of Chinese medicine ointment for treating herpesvirus type recurrent oral ulceration；Application number：CN201510281481.2；Applicant：
Wang Yubo；
Summary：A kind of Chinese medicine ointment for treating herpesvirus type recurrent oral ulceration, it is by Rose Mallow Root, honeybee sugar bowl, wild Rosa roxburghii, black hair
Fern, Radix Baccaureae ramiflorae, Embelia laeta root, viburnum dilatatum thunb, Euphorbia thymifolia, purling withered leaf, Mazus japonicus, see blue or green blood, red mulberry, Uncinata Spikemoss Herb, tamarind, Scabrous Mosla Herb
It is mixed by extraction concentration with vitamin B, Chinese medicine composition of the present invention can nourish cloudy kidney, clearing heat and removing internal heat, detoxicating, relieving inflammation,
Human endocrine is balanced, removes the toxin built up in human body comprehensively, enhancing body can be induced actively the resistance of infection
Ulcer healing, healing time is substantially speeded up, removes ulcer rapidly, reach the purpose for the treatment of.
2nd, a kind of medicine for being used to treat canker sore；Application number：CN201510734553.4；Applicant：Chen Guanghui；
Summary：A kind of medicine for being used to treat canker sore, its component form for following raw material medicaments in part by weight：Herba Lycopi 12-18
Part, gypsum 8-12 parts, cape jasmine 8-12 parts, capsule of weeping forsythia 8-12 parts, myrrh 8-12 parts, frankincense 8-12 parts, goldenrod 8-12 parts, chrysanthemum
8-12 parts, Chinese violet 8-12 parts, radix semiaquilegiae 8-12 parts, motherwort 8-12 parts, radix glycyrrhizae 3-8 parts；Preparation method：By in raw medicinal material
Herba Lycopi, gypsum, cape jasmine, the capsule of weeping forsythia, myrrh, frankincense, goldenrod, chrysanthemum, Chinese violet, radix semiaquilegiae, motherwort, radix glycyrrhizae drying, are crushed,
It is well mixed, 100 mesh sieves are crossed, medicinal powder packing can be prepared by；The all medicines of we are used in combination, treatment canker sore, positive effect,
It is evident in efficacy.
3rd, a kind of Chinese medicine preparation for treating canker sore as well as preparation method and application thereof；Application number：
CN201510902377.0；Applicant：Yuyao City Qiao Di electrical apparatus factories；
Summary：The invention discloses a kind of Chinese medicine preparation for treating canker sore as well as preparation method and application thereof, the Chinese medicine system
Agent is made up of according to mass fraction 6~9 parts of 30~45 parts of green bristlegrass, 15~28 parts of Horseweed Herb and madder；By above-mentioned raw materials medicinal material
Mix in proportion, be ground into powder；Add cold water soak, decoct, filtering, obtain the first filtrate and the first filter residue；Add cold water, decoct,
Filtering obtains the second filtrate and the second filter residue；First filtrate and the second filtrate are mixed, is concentrated under reduced pressure as thick paste, is dried, crush,
Sieve to obtain fine powder；Starch is added into fine powder to be well mixed, and powder is made, produces.The present invention has clearing heat and detoxicating, scattered stagnation resolvation
The effect of swollen, cooling blood and hemostasis, eliminating blood stasis and smoothing collaterals, myogenic treat sore, is applied on the clinical treatment of canker sore, shows with curative effect
The characteristics of writing that reliable, treatment time is short, quick, difficulty in relapse after healing, and having no toxic side effect
The external application Chinese medicine of data disclosed above also has the effect for the treatment of canker sore, but basis is different from the present invention, treatment
Effect also differs.
The content of the invention
The purpose of the present invention is to provide a kind of Yao nationality medicine external pulvis different from existing external application Chinese medicine to market, can treat mouth
Chamber ulcer, there is the effect of clearing heat and detoxicating, dissipate stasis of blood hemostasis, anti-inflammation, swelling and pain relieving, used suitable for canker sore patient.
To achieve these goals, the technical scheme is that：
The Yao nationality medicine external pulvis for treating canker sore is made of the raw material including following compositions：Hairy euphorbia 8-10 parts, sour rattan
Root 3-5 parts, goldenrod 3-5 parts, blank sheet of paper fan 2-3 parts.
The present invention preparation method be：
Hairy euphorbia, sour rattan root, goldenrod and blank sheet of paper fan are taken by weight ratio, by raw material drying, are then fed into medicinal herb grinder
Middle attrition grinding, after be mixed evenly, cross 100-120 mesh sieves, obtain fine powder and be placed in microwave dryer and sterilized, you can bottling
Obtain finished product external pulvis.
Medically research shows that the herbal component selected by the present invention has following effect：
Above-described hairy euphorbia, it is Euphorbiaceae euphorbia hairy euphorbia, with all herbal medicine,【Classification system】Euphorbia
Hirta L.,【Alias】：Fly mutually careless, newborn seed grass, fly upward greatly,【Meridian distribution of property and flavor】：Acrid flavour, acid, cool in nature, return lung, bladder, large intestine
Through,【Major function】：Bactericidal antiphlogistic, clearing heat and detoxicating, removing dampness through diuresis and relieving itching, cure mainly furuncle swelling toxin, noma（Gum is red and swollen, pain of festering,
Flow the diseases such as rancid purulence blood）.《The sward property of medicine is standby will》：" fire of deficiency type of swimming is controlled, applies the swelling and pain of tooth meat." it is demonstrated experimentally that hairy euphorbia water extract
There is the analgesic activity of similar morphine.
Above-described sour rattan root, be Myrsinacea plant common embelia fruit root and branches and leaves,【Classification system】Embelia
Laeta (L.) Mez,【Alias】：Common embelia root branchlet and leaf, sour rattan, exceedingly high despot, big gun rattan, saturating earthworm, the female acid of chicken, vinegar wood, seabed are carried on the back in vain
Dragon, enter earthworm,【Meridian distribution of property and flavor】：It is sour, puckery, cool in nature, the thoughts of returning home, the spleen channel,【Major function】：Invigorating the spleen, clearing heat and detoxicating, the scattered stasis of blood is stopped
Blood, detoxification detumescence.Cure mainly pharyngitis, gingiva bleeding gingival hemorrhage, boil ulcer, pruitus, hemorrhoid gall, root, leaf：Stasis-dispelling and pain-killing,
Anti-inflammatory, antidiarrheal.
Above-described goldenrod, all herbal medicine,【Classification system】Solidago decurrens Lour,【Alias】：
Sticky dish, Fallopia nervosa（Yunnan）, golden radix bupleuri（Southwest）, the thick conjunction in mountain, tiger urine, sweet vernal grass, snakehead king, grass all over the mountain, hundred grass,
Golden radix bupleuri, towards day common anotis herb, an arrow, small radix bupleuri.Chrysanthemum asarum, chrysanthemum cynanchum paniculatum, FLOS CHRYSANTHEMI INDICI, half, mountain side perfume (or spice), spill golden flower,
Thousand Huang, native Herba Lycopi, hundred roots, iron gold are turned, yellow radix bupleuri, Xian are careless, small Radix Alangii, chrysanthemum kalimeris, big Toxin-Vanquishing, RADIX BUPLEURI SCORZONERIFOLII, Huang
Young, red glue bitter dish, cynanchum paniculatum, great Ye cavalerie mosla herbs, golden key, yellow, chrysanthemum all over the mountain are spent,【Meridian distribution of property and flavor】：It is pungent, bitter, it is cool, return
Lung, Liver Channel,【Major function】：Wind and heat dispersing, anti-inflammation is clearing heat and detoxicating, and detumescence is except pain, and available for sore swollen toxin, the traditional Chinese medical science is recognized
There are wind and heat dispersing, the effect of subdhing swelling and detoxicating and effect for goldenrod.There is patient's case：Traumatism and bleeding is controlled, goldenrod is dried
Grind and remove in wound, take orally simultaneously, every time 3 ~ 6g.Treatment 100, effectively.
Above-described blank sheet of paper fan, the complete stool of madder wort Radix Mussaendae,【Classification system】Mussaenda
Pubescens Ait.f.,【Alias】：Tea is respected, hundred solve rattans, broomwort, hair Radix Mussaendae,【Meridian distribution of property and flavor】It is sweet, cool in nature, nothing
Poison,【Major function】：It is clearing heat and detoxicating, promote the production of body fluid, inducing diuresis and reducing edema, preventing phlegm from forming and stopping coughing, Liang Xue Solution heat, dial foreign matter.
The pharmacological function of each composition is in the Yao nationality medicine external pulvis of present invention treatment canker sore effect：
Hairy euphorbia bactericidal antiphlogistic, clearing heat and detoxicating, removing dampness through diuresis and relieving itching, cure mainly furuncle swelling toxin, noma（Gum is red and swollen, pain of festering, and stream is rotten
The diseases such as smelly purulence blood）, and there is the effect of analgesia.
Sour rattan root energy invigorating the spleen, it is clearing heat and detoxicating, dissipate stasis of blood hemostasis, detoxification detumescence, pharyngitis is cured mainly, gingiva bleeding gingival hemorrhage, there is anti-inflammatory
Analgesic efficacy.
Goldenrod wind and heat dispersing, anti-inflammation is clearing heat and detoxicating, and detumescence can treat traumatism and bleeding except pain.
Blank sheet of paper fan is clearing heat and detoxicating, promotes the production of body fluid, inducing diuresis and reducing edema.
In above component, hairy euphorbia is monarch drug in a prescription, and sour rattan root, goldenrod, blank sheet of paper fan are ministerial drug.
It is exactly Yao nationality medicine external pulvis of present invention treatment canker sore and preparation method thereof above, maximizes and retain in various raw materials
Clearing heat and detoxicating, dissipate stasis of blood hemostasis, anti-inflammation, the plurality of Chinese element of swelling and pain relieving.
Beneficial effects of the present invention：
1st, the present invention is by the refined purpose for forming, treatment canker sore being reached using Chinese herbal medicine itself effect of Yao nationality's ancient prescription, medicine
Through affected part, it is evident in efficacy, and have no side effect.
2nd, for compared to oral drugs, powder is quick, can eliminate ulcer surface pain rapidly, palliate the agonizing sufferings, Ji Nengzhi
Mark can also effect a permanent cure.
3rd, raw material are widely present and cheap, and medicine cost is low, can meet that middle and low income many patients use.
Application Example：
Clinic carries out this precious jade medicine external pulvis to totally 76 canker sore patients and is treated and be tracked further consultation, patient age
From 15 years old to 62 years old.
Criterion of therapeutical effect：
1st, treatment is invalid：Ulcer is unchanged, and clinical symptoms do not change, or has new hair ulcer.
2nd, treatment is effective：Ulcer is painless, and ulcer surface largely heals, and clinical symptoms reduce 50%, does not have new hair to burst
Ulcer.
3rd, treatment recovery from illness：Ulcer is painless, ulcer surface healing, clinical symptom disappearance, does not there is new hair ulcer.
Therapeutic scheme：
Treatment group：Affected part uses external preparation 4-5 times daily, and continuous use is observed once for a course for the treatment of further consultation on the 4th, totally 2
The course for the treatment of；
Control group：Compound chlorhexidine gargle, 2 times a day；Compound eupatorium syrup, 3 times a day, the same treatment group for the treatment of time；
Obtain following clinical data：
| Illness | After treatment | It is efficient | Cure rate | Use embodiment |
| The people for the treatment of group 25 | 11 symptoms are effective；14 symptom recoveries from illness | 100% | 56% | Embodiment 1 |
| The people for the treatment of group 25 | 12 symptoms are effective；12 symptom recoveries from illness | 96% | 48% | Embodiment 2 |
| The people of control group 26 | 11 symptoms are effective；8 symptom recoveries from illness | 73% | 31% | - |
Clinical test shows：Yao nationality medicine external pulvis of the present invention has significant curative effect to canker sore, efficient close to 100%, and subsequently
Further consultation finds no new hair ulcer and produced.
Model case：
It is the model case using Yao nationality medicine external pulvis treatment canker sore below:
Embodiment 1：Lee, man, Laibin, Guangxi Province people, 24 years old, because of edible excessive barbecue, fried food, drink beyond one's capacity, it is raw on the inside of lip
Go out ulcer at 3, pain is red and swollen at ulcer, goes to examination in hospital for canker sore caused by excessive internal heat, then using the embodiment of the present invention 1
Powder is treated, daily to use 4-5 time, has been feels pain sense disappearance when just using, after 3 days, ulcer surface base
This recovery from illness.
Embodiment 2：Tang, female, people from Liuzhou, 34 years old, have a fever after catching a cold 2 days, suffer from canker sore at 2, gum redness,
At gum at ulcer 1, go to examination in hospital for canker sore caused by passive protective physical fitness decline, then using the embodiment of the present invention 2
Powder is treated, daily to use 4-5 times, after 3 days, ulcer recovery from illness.
Embodiment 3：Yuan, man, Guangxi Gold show people, 45 years old, canker sore recurrent exerbation was had a surplus for 3 months, every time from enforcement
To be treated with watermelon crystal spray, pain is alleviated in therapeutic process, but still fails to cure completely, while with having sore throat,
It is canker sore caused by bacterium infection to go to examination in hospital, is then treated using the powder of the embodiment of the present invention 2, daily to use
4-5 times, after 7 days, ulcer surface is largely fully recovered, and has no new hair ulcer, is treated to after 12 days, ulcer recovery from illness,
And further consultation no relapse after one month.
Embodiment 4：Xiao, man, Laibin, Guangxi Province people, 42 years old, at tongue canker sore two, and feel breathes hard, the traditional Chinese medical science
Check as insufficiency of the spleen canker sore, thick libngual fur, then treated using the powder of the embodiment of the present invention 1, it is daily to use 3 times, add
Eat some invigorating the spleen decoction of medicinal ingredients, after 7 days, ulcer recovery from illness.
Claims (2)
1. a kind of Yao nationality medicine external pulvis for treating canker sore, it is characterised in that by the herbal raw material system of following weight proportion
Into：Hairy euphorbia 8-10 parts, sour rattan root 3-5 parts, goldenrod 3-5 parts, blank sheet of paper fan 2-3 parts；Obtained medicine composition is outer
Use powder.
2. the Yao nationality medicine external pulvis for the treatment of canker sore as claimed in claim 1, it is characterised in that：The preparation method of powder is such as
Under：
Hairy euphorbia, sour rattan root, goldenrod and blank sheet of paper fan are taken by weight ratio, by raw material drying, are then fed into medicinal herb grinder
Middle attrition grinding, after be mixed evenly, cross 100-120 mesh sieves, obtain fine powder and be placed in microwave dryer and sterilized, you can bottling
Obtain finished product external pulvis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711002578.0A CN107823293B (en) | 2017-10-24 | 2017-10-24 | Yao medicine external powder for treating oral ulcer and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711002578.0A CN107823293B (en) | 2017-10-24 | 2017-10-24 | Yao medicine external powder for treating oral ulcer and preparation method thereof |
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| Publication Number | Publication Date |
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| CN107823293A true CN107823293A (en) | 2018-03-23 |
| CN107823293B CN107823293B (en) | 2020-12-04 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109222533A (en) * | 2018-09-17 | 2019-01-18 | 金秀瑶族自治县瑶医医院 | Tranquilizing the mind precious jade medicine medicine-filled pillow and preparation method thereof |
| CN115463067A (en) * | 2022-10-24 | 2022-12-13 | 上海咏旭生物科技有限公司 | Oral care composition containing climbing groundsel herb extract and erigeron breviscapus extract and application thereof |
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| CN103784847A (en) * | 2014-01-09 | 2014-05-14 | 山东省立医院 | External powder for treating dental ulcer |
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2017
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103784847A (en) * | 2014-01-09 | 2014-05-14 | 山东省立医院 | External powder for treating dental ulcer |
Non-Patent Citations (2)
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| 程金生等: "《客家中草药图鉴及民间验方》", 31 August 2016 * |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109222533A (en) * | 2018-09-17 | 2019-01-18 | 金秀瑶族自治县瑶医医院 | Tranquilizing the mind precious jade medicine medicine-filled pillow and preparation method thereof |
| CN115463067A (en) * | 2022-10-24 | 2022-12-13 | 上海咏旭生物科技有限公司 | Oral care composition containing climbing groundsel herb extract and erigeron breviscapus extract and application thereof |
| CN115463067B (en) * | 2022-10-24 | 2023-12-12 | 上海咏旭生物科技有限公司 | Oral care composition containing senecio scandens extract and erigeron breviscapus extract and application thereof |
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