CN107823293A - Treat Yao nationality medicine external pulvis of canker sore and preparation method thereof - Google Patents
Treat Yao nationality medicine external pulvis of canker sore and preparation method thereof Download PDFInfo
- Publication number
- CN107823293A CN107823293A CN201711002578.0A CN201711002578A CN107823293A CN 107823293 A CN107823293 A CN 107823293A CN 201711002578 A CN201711002578 A CN 201711002578A CN 107823293 A CN107823293 A CN 107823293A
- Authority
- CN
- China
- Prior art keywords
- canker sore
- parts
- external pulvis
- yao nationality
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000020670 canker sore Diseases 0.000 title claims abstract description 39
- 239000003814 drug Substances 0.000 title claims abstract description 36
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 239000000843 powder Substances 0.000 claims abstract description 16
- 235000000914 Solidago virgaurea Nutrition 0.000 claims abstract description 12
- 241000345998 Calamus manan Species 0.000 claims abstract description 11
- 241000221079 Euphorbia <genus> Species 0.000 claims abstract description 11
- 244000197975 Solidago virgaurea Species 0.000 claims abstract description 11
- 235000012950 rattan cane Nutrition 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 9
- 239000000203 mixture Substances 0.000 claims abstract description 6
- 238000001035 drying Methods 0.000 claims abstract description 4
- 238000000227 grinding Methods 0.000 claims description 2
- 239000008361 herbal raw material Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 17
- 208000002193 Pain Diseases 0.000 abstract description 12
- 230000036407 pain Effects 0.000 abstract description 12
- 239000008280 blood Substances 0.000 abstract description 11
- 210000004369 blood Anatomy 0.000 abstract description 11
- 206010042674 Swelling Diseases 0.000 abstract description 7
- 230000008961 swelling Effects 0.000 abstract description 7
- 206010061218 Inflammation Diseases 0.000 abstract description 6
- 229940079593 drug Drugs 0.000 abstract description 5
- 230000023597 hemostasis Effects 0.000 abstract description 5
- 208000025865 Ulcer Diseases 0.000 description 25
- 231100000397 ulcer Toxicity 0.000 description 24
- 208000024891 symptom Diseases 0.000 description 10
- 238000011084 recovery Methods 0.000 description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 210000000952 spleen Anatomy 0.000 description 7
- 235000007516 Chrysanthemum Nutrition 0.000 description 6
- 201000010099 disease Diseases 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 244000189548 Chrysanthemum x morifolium Species 0.000 description 5
- 230000007812 deficiency Effects 0.000 description 5
- 239000000796 flavoring agent Substances 0.000 description 5
- 235000019634 flavors Nutrition 0.000 description 5
- 239000003053 toxin Substances 0.000 description 5
- 231100000765 toxin Toxicity 0.000 description 5
- 208000032843 Hemorrhage Diseases 0.000 description 4
- 201000007100 Pharyngitis Diseases 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 4
- 238000009826 distribution Methods 0.000 description 4
- 230000035619 diuresis Effects 0.000 description 4
- 239000000706 filtrate Substances 0.000 description 4
- 230000035876 healing Effects 0.000 description 4
- 208000002399 aphthous stomatitis Diseases 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 241000411851 herbal medicine Species 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 210000004400 mucous membrane Anatomy 0.000 description 3
- 230000000306 recurrent effect Effects 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 235000003717 Boswellia sacra Nutrition 0.000 description 2
- 240000007551 Boswellia serrata Species 0.000 description 2
- 235000012035 Boswellia serrata Nutrition 0.000 description 2
- 244000025254 Cannabis sativa Species 0.000 description 2
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 2
- 240000007311 Commiphora myrrha Species 0.000 description 2
- 235000006965 Commiphora myrrha Nutrition 0.000 description 2
- 241000843353 Embelia Species 0.000 description 2
- 241001438931 Embelia laeta Species 0.000 description 2
- 241000576429 Forsythia suspensa Species 0.000 description 2
- 239000004863 Frankincense Substances 0.000 description 2
- 206010017553 Furuncle Diseases 0.000 description 2
- 244000111489 Gardenia augusta Species 0.000 description 2
- 235000018958 Gardenia augusta Nutrition 0.000 description 2
- 206010018276 Gingival bleeding Diseases 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 240000007890 Leonurus cardiaca Species 0.000 description 2
- 235000000802 Leonurus cardiaca ssp. villosus Nutrition 0.000 description 2
- 208000002720 Malnutrition Diseases 0.000 description 2
- 241000361919 Metaphire sieboldi Species 0.000 description 2
- 241000717679 Mosla Species 0.000 description 2
- 206010028034 Mouth ulceration Diseases 0.000 description 2
- 235000007265 Myrrhis odorata Nutrition 0.000 description 2
- 241000123069 Ocyurus chrysurus Species 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 206010061926 Purulence Diseases 0.000 description 2
- 206010042135 Stomatitis necrotising Diseases 0.000 description 2
- 240000006688 Telosma cordata Species 0.000 description 2
- 235000017352 Telosma cordata Nutrition 0.000 description 2
- 241000331449 Vincetoxicum pycnostelma Species 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 239000002260 anti-inflammatory agent Substances 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000001741 anti-phlogistic effect Effects 0.000 description 2
- 235000021168 barbecue Nutrition 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000001784 detoxification Methods 0.000 description 2
- 230000008034 disappearance Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 210000004195 gingiva Anatomy 0.000 description 2
- 229910052602 gypsum Inorganic materials 0.000 description 2
- 239000010440 gypsum Substances 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000001071 malnutrition Effects 0.000 description 2
- 235000000824 malnutrition Nutrition 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 description 2
- 201000008585 noma Diseases 0.000 description 2
- 208000015380 nutritional deficiency disease Diseases 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 241001529453 unidentified herpesvirus Species 0.000 description 2
- 235000019156 vitamin B Nutrition 0.000 description 2
- 239000011720 vitamin B Substances 0.000 description 2
- 240000004178 Anthoxanthum odoratum Species 0.000 description 1
- 241000256844 Apis mellifera Species 0.000 description 1
- 241000758794 Asarum Species 0.000 description 1
- 240000004183 Bongardia chrysogonum Species 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 244000067602 Chamaesyce hirta Species 0.000 description 1
- 244000067601 Chamaesyce thymifolia Species 0.000 description 1
- 241001597062 Channa argus Species 0.000 description 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 240000005250 Chrysanthemum indicum Species 0.000 description 1
- 244000241235 Citrullus lanatus Species 0.000 description 1
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 1
- 206010009900 Colitis ulcerative Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 244000074881 Conyza canadensis Species 0.000 description 1
- 235000004385 Conyza canadensis Nutrition 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 208000011231 Crohn disease Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000735527 Eupatorium Species 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 208000032139 Halitosis Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 241000590002 Helicobacter pylori Species 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- 241001252483 Kalimeris Species 0.000 description 1
- 208000008771 Lymphadenopathy Diseases 0.000 description 1
- 206010025476 Malabsorption Diseases 0.000 description 1
- 208000004155 Malabsorption Syndromes Diseases 0.000 description 1
- 244000101461 Mazus japonicus Species 0.000 description 1
- 244000235756 Microcos paniculata Species 0.000 description 1
- 240000000249 Morus alba Species 0.000 description 1
- 235000014679 Morus rubra var. rubra Nutrition 0.000 description 1
- 235000014677 Morus rubra var. tomentosa Nutrition 0.000 description 1
- 241000409983 Mussaenda pubescens Species 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 241000282376 Panthera tigris Species 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 240000002547 Rosa roxburghii Species 0.000 description 1
- 235000000640 Rosa roxburghii Nutrition 0.000 description 1
- 241000195974 Selaginella Species 0.000 description 1
- 235000010086 Setaria viridis var. viridis Nutrition 0.000 description 1
- 241000992149 Solidago decurrens Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 208000007107 Stomach Ulcer Diseases 0.000 description 1
- 241000194023 Streptococcus sanguinis Species 0.000 description 1
- 240000004584 Tamarindus indica Species 0.000 description 1
- 235000004298 Tamarindus indica Nutrition 0.000 description 1
- 201000006704 Ulcerative Colitis Diseases 0.000 description 1
- 241000317854 Uncinata Species 0.000 description 1
- 241000673664 Viburnum dilatatum Species 0.000 description 1
- 229930003270 Vitamin B Natural products 0.000 description 1
- 229930003779 Vitamin B12 Natural products 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229960003260 chlorhexidine Drugs 0.000 description 1
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 208000000718 duodenal ulcer Diseases 0.000 description 1
- 230000007937 eating Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 208000022532 enlargement of lymph nodes Diseases 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 201000005917 gastric ulcer Diseases 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- NPEWZDADCAZMNF-UHFFFAOYSA-N gold iron Chemical compound [Fe].[Au] NPEWZDADCAZMNF-UHFFFAOYSA-N 0.000 description 1
- 244000230342 green foxtail Species 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229940037467 helicobacter pylori Drugs 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000010977 jade Substances 0.000 description 1
- 230000003780 keratinization Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 244000144886 lesser spear grass Species 0.000 description 1
- 238000013332 literature search Methods 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000003821 menstrual periods Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 229960005181 morphine Drugs 0.000 description 1
- 230000001114 myogenic effect Effects 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000003119 painkilling effect Effects 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000009738 saturating Methods 0.000 description 1
- 210000001584 soft palate Anatomy 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000004206 stomach function Effects 0.000 description 1
- 235000011595 sweet vernalgrass Nutrition 0.000 description 1
- 230000009182 swimming Effects 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 230000001720 vestibular Effects 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- 235000019163 vitamin B12 Nutrition 0.000 description 1
- 229940046001 vitamin b complex Drugs 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of Yao nationality medicine external pulvis for treating canker sore and preparation method thereof, it is made of the raw material including following compositions：The effect of hairy euphorbia, sour rattan root, goldenrod and blank sheet of paper fan, the raw material drying of said ratio pulverizes and sieves, is stirred, Yao nationality medicine traditional Chinese powder medicine is made, and this external pulvis is clearing heat and detoxicating, dissipate stasis of blood hemostasis, anti-inflammation, swelling and pain relieving.There is the effect of good to all kinds of canker sore patients, easy to operate, safety, few side effects, can guide drugs to illness station.
Description
Technical field
The present invention relates to a kind of Yao nationality medicine external pulvis and preparation method thereof, more particularly to the external powder for the treatment of canker sore
Agent and preparation method.
Background technology
Canker sore is commonly called as " aphtha ", is a kind of common ulcerative damages illness for betiding mucous membrane of mouth, is more common in
The positions such as lip inner side, tongue, tongue abdomen, cheek mucous membrane, vestibular ditch, soft palate, the mucous membrane at these positions lack keratinization layer or angling compared with
Difference.Tongue ulcer, which refers to, betides tongue, the canker sore of tongue belly position.Sharp ache when canker sore is broken out, local cusalgia are bright
Aobvious, severe patient can also influence diet, speak, and very big inconvenience is caused to daily life；When serious can concurrently halitosis, chronic pharyngitis,
The constitutional symptom such as constipation, headache, dizziness, nausea, weak, irritated, heating, enlargement of lymph nodes.
Canker sore is the result of many factors comprehensive function, it include local trauma, stress, food,
Medicine, malnutrition, hormonal readiness changes and vitamin or microelement deficiencies.Systemic disease, heredity, immune and microorganism
It may be played an important role in generation, development in canker sore.Such as lack trace element zinc, iron, lack folic acid, vitamin B12
And malnutrition etc., immunologic function, the possibility of increase canker sore morbidity can be reduced；Streptococcus sanguis and helicobacter pylori etc.
Bacterium is also in close relations with canker sore.Canker sore generally imply that body may have potential systemic disease, canker sore
With gastric ulcer, duodenal ulcer, ulcerative colitis, regional enteritis, hepatitis, female menstrual period, vitamin B complex malabsorption
Disease, vegetative nerve functional disturbance disease etc. are relevant.
The traditional Chinese medical science thinks this sick generation, and external cause is referred to and smoked and drink based on heat toxin mostly, excessively fed fried, barbecue,
Pungent food, cause heart spleen position, lung, stomach and liver and gall position the situation of accumulated heat occur, ultimately result in excessive internal heat, aphtha
The appearance of disease, this belongs to excess fire, and morbidity is quickly.Internal cause is mostly feelings will internal injury, eating and drinking without temperance, caused by chamber overstrain, general feelings
It is due to continuously to stay up late under condition, negative emotions are tired, and the fire of deficiency type caused by pressure is excessive etc., some are getting in years and body
Weaker patient, spleen and stomach function sustain damage, and cause middle burnt hinge normally to work, and upper and lower mechanism of qi can not connect,
Excessive fire in heart, this, which is also resulted in, there is aphtha, and this falls within the chronic diseases marked by deficiency of vital energy, and the morbidity of the fire of deficiency type is relatively slow.
We pass through literature search, it has been found that some Chinese medicine preparations on treating canker sore, such as：
1st, a kind of Chinese medicine ointment for treating herpesvirus type recurrent oral ulceration；Application number：CN201510281481.2；Applicant：
Wang Yubo；
Summary：A kind of Chinese medicine ointment for treating herpesvirus type recurrent oral ulceration, it is by Rose Mallow Root, honeybee sugar bowl, wild Rosa roxburghii, black hair
Fern, Radix Baccaureae ramiflorae, Embelia laeta root, viburnum dilatatum thunb, Euphorbia thymifolia, purling withered leaf, Mazus japonicus, see blue or green blood, red mulberry, Uncinata Spikemoss Herb, tamarind, Scabrous Mosla Herb
It is mixed by extraction concentration with vitamin B, Chinese medicine composition of the present invention can nourish cloudy kidney, clearing heat and removing internal heat, detoxicating, relieving inflammation,
Human endocrine is balanced, removes the toxin built up in human body comprehensively, enhancing body can be induced actively the resistance of infection
Ulcer healing, healing time is substantially speeded up, removes ulcer rapidly, reach the purpose for the treatment of.
2nd, a kind of medicine for being used to treat canker sore；Application number：CN201510734553.4；Applicant：Chen Guanghui；
Summary：A kind of medicine for being used to treat canker sore, its component form for following raw material medicaments in part by weight：Herba Lycopi 12-18
Part, gypsum 8-12 parts, cape jasmine 8-12 parts, capsule of weeping forsythia 8-12 parts, myrrh 8-12 parts, frankincense 8-12 parts, goldenrod 8-12 parts, chrysanthemum
8-12 parts, Chinese violet 8-12 parts, radix semiaquilegiae 8-12 parts, motherwort 8-12 parts, radix glycyrrhizae 3-8 parts；Preparation method：By in raw medicinal material
Herba Lycopi, gypsum, cape jasmine, the capsule of weeping forsythia, myrrh, frankincense, goldenrod, chrysanthemum, Chinese violet, radix semiaquilegiae, motherwort, radix glycyrrhizae drying, are crushed,
It is well mixed, 100 mesh sieves are crossed, medicinal powder packing can be prepared by；The all medicines of we are used in combination, treatment canker sore, positive effect,
It is evident in efficacy.
3rd, a kind of Chinese medicine preparation for treating canker sore as well as preparation method and application thereof；Application number：
CN201510902377.0；Applicant：Yuyao City Qiao Di electrical apparatus factories；
Summary：The invention discloses a kind of Chinese medicine preparation for treating canker sore as well as preparation method and application thereof, the Chinese medicine system
Agent is made up of according to mass fraction 6~9 parts of 30~45 parts of green bristlegrass, 15~28 parts of Horseweed Herb and madder；By above-mentioned raw materials medicinal material
Mix in proportion, be ground into powder；Add cold water soak, decoct, filtering, obtain the first filtrate and the first filter residue；Add cold water, decoct,
Filtering obtains the second filtrate and the second filter residue；First filtrate and the second filtrate are mixed, is concentrated under reduced pressure as thick paste, is dried, crush,
Sieve to obtain fine powder；Starch is added into fine powder to be well mixed, and powder is made, produces.The present invention has clearing heat and detoxicating, scattered stagnation resolvation
The effect of swollen, cooling blood and hemostasis, eliminating blood stasis and smoothing collaterals, myogenic treat sore, is applied on the clinical treatment of canker sore, shows with curative effect
The characteristics of writing that reliable, treatment time is short, quick, difficulty in relapse after healing, and having no toxic side effect
The external application Chinese medicine of data disclosed above also has the effect for the treatment of canker sore, but basis is different from the present invention, treatment
Effect also differs.
The content of the invention
The purpose of the present invention is to provide a kind of Yao nationality medicine external pulvis different from existing external application Chinese medicine to market, can treat mouth
Chamber ulcer, there is the effect of clearing heat and detoxicating, dissipate stasis of blood hemostasis, anti-inflammation, swelling and pain relieving, used suitable for canker sore patient.
To achieve these goals, the technical scheme is that：
The Yao nationality medicine external pulvis for treating canker sore is made of the raw material including following compositions：Hairy euphorbia 8-10 parts, sour rattan
Root 3-5 parts, goldenrod 3-5 parts, blank sheet of paper fan 2-3 parts.
The present invention preparation method be：
Hairy euphorbia, sour rattan root, goldenrod and blank sheet of paper fan are taken by weight ratio, by raw material drying, are then fed into medicinal herb grinder
Middle attrition grinding, after be mixed evenly, cross 100-120 mesh sieves, obtain fine powder and be placed in microwave dryer and sterilized, you can bottling
Obtain finished product external pulvis.
Medically research shows that the herbal component selected by the present invention has following effect：
Above-described hairy euphorbia, it is Euphorbiaceae euphorbia hairy euphorbia, with all herbal medicine,【Classification system】Euphorbia
Hirta L.,【Alias】：Fly mutually careless, newborn seed grass, fly upward greatly,【Meridian distribution of property and flavor】：Acrid flavour, acid, cool in nature, return lung, bladder, large intestine
Through,【Major function】：Bactericidal antiphlogistic, clearing heat and detoxicating, removing dampness through diuresis and relieving itching, cure mainly furuncle swelling toxin, noma（Gum is red and swollen, pain of festering,
Flow the diseases such as rancid purulence blood）.《The sward property of medicine is standby will》：" fire of deficiency type of swimming is controlled, applies the swelling and pain of tooth meat." it is demonstrated experimentally that hairy euphorbia water extract
There is the analgesic activity of similar morphine.
Above-described sour rattan root, be Myrsinacea plant common embelia fruit root and branches and leaves,【Classification system】Embelia
Laeta (L.) Mez,【Alias】：Common embelia root branchlet and leaf, sour rattan, exceedingly high despot, big gun rattan, saturating earthworm, the female acid of chicken, vinegar wood, seabed are carried on the back in vain
Dragon, enter earthworm,【Meridian distribution of property and flavor】：It is sour, puckery, cool in nature, the thoughts of returning home, the spleen channel,【Major function】：Invigorating the spleen, clearing heat and detoxicating, the scattered stasis of blood is stopped
Blood, detoxification detumescence.Cure mainly pharyngitis, gingiva bleeding gingival hemorrhage, boil ulcer, pruitus, hemorrhoid gall, root, leaf：Stasis-dispelling and pain-killing,
Anti-inflammatory, antidiarrheal.
Above-described goldenrod, all herbal medicine,【Classification system】Solidago decurrens Lour,【Alias】：
Sticky dish, Fallopia nervosa（Yunnan）, golden radix bupleuri（Southwest）, the thick conjunction in mountain, tiger urine, sweet vernal grass, snakehead king, grass all over the mountain, hundred grass,
Golden radix bupleuri, towards day common anotis herb, an arrow, small radix bupleuri.Chrysanthemum asarum, chrysanthemum cynanchum paniculatum, FLOS CHRYSANTHEMI INDICI, half, mountain side perfume (or spice), spill golden flower,
Thousand Huang, native Herba Lycopi, hundred roots, iron gold are turned, yellow radix bupleuri, Xian are careless, small Radix Alangii, chrysanthemum kalimeris, big Toxin-Vanquishing, RADIX BUPLEURI SCORZONERIFOLII, Huang
Young, red glue bitter dish, cynanchum paniculatum, great Ye cavalerie mosla herbs, golden key, yellow, chrysanthemum all over the mountain are spent,【Meridian distribution of property and flavor】：It is pungent, bitter, it is cool, return
Lung, Liver Channel,【Major function】：Wind and heat dispersing, anti-inflammation is clearing heat and detoxicating, and detumescence is except pain, and available for sore swollen toxin, the traditional Chinese medical science is recognized
There are wind and heat dispersing, the effect of subdhing swelling and detoxicating and effect for goldenrod.There is patient's case：Traumatism and bleeding is controlled, goldenrod is dried
Grind and remove in wound, take orally simultaneously, every time 3 ~ 6g.Treatment 100, effectively.
Above-described blank sheet of paper fan, the complete stool of madder wort Radix Mussaendae,【Classification system】Mussaenda
Pubescens Ait.f.,【Alias】：Tea is respected, hundred solve rattans, broomwort, hair Radix Mussaendae,【Meridian distribution of property and flavor】It is sweet, cool in nature, nothing
Poison,【Major function】：It is clearing heat and detoxicating, promote the production of body fluid, inducing diuresis and reducing edema, preventing phlegm from forming and stopping coughing, Liang Xue Solution heat, dial foreign matter.
The pharmacological function of each composition is in the Yao nationality medicine external pulvis of present invention treatment canker sore effect：
Hairy euphorbia bactericidal antiphlogistic, clearing heat and detoxicating, removing dampness through diuresis and relieving itching, cure mainly furuncle swelling toxin, noma（Gum is red and swollen, pain of festering, and stream is rotten
The diseases such as smelly purulence blood）, and there is the effect of analgesia.
Sour rattan root energy invigorating the spleen, it is clearing heat and detoxicating, dissipate stasis of blood hemostasis, detoxification detumescence, pharyngitis is cured mainly, gingiva bleeding gingival hemorrhage, there is anti-inflammatory
Analgesic efficacy.
Goldenrod wind and heat dispersing, anti-inflammation is clearing heat and detoxicating, and detumescence can treat traumatism and bleeding except pain.
Blank sheet of paper fan is clearing heat and detoxicating, promotes the production of body fluid, inducing diuresis and reducing edema.
In above component, hairy euphorbia is monarch drug in a prescription, and sour rattan root, goldenrod, blank sheet of paper fan are ministerial drug.
It is exactly Yao nationality medicine external pulvis of present invention treatment canker sore and preparation method thereof above, maximizes and retain in various raw materials
Clearing heat and detoxicating, dissipate stasis of blood hemostasis, anti-inflammation, the plurality of Chinese element of swelling and pain relieving.
Beneficial effects of the present invention：
1st, the present invention is by the refined purpose for forming, treatment canker sore being reached using Chinese herbal medicine itself effect of Yao nationality's ancient prescription, medicine
Through affected part, it is evident in efficacy, and have no side effect.
2nd, for compared to oral drugs, powder is quick, can eliminate ulcer surface pain rapidly, palliate the agonizing sufferings, Ji Nengzhi
Mark can also effect a permanent cure.
3rd, raw material are widely present and cheap, and medicine cost is low, can meet that middle and low income many patients use.
Application Example：
Clinic carries out this precious jade medicine external pulvis to totally 76 canker sore patients and is treated and be tracked further consultation, patient age
From 15 years old to 62 years old.
Criterion of therapeutical effect：
1st, treatment is invalid：Ulcer is unchanged, and clinical symptoms do not change, or has new hair ulcer.
2nd, treatment is effective：Ulcer is painless, and ulcer surface largely heals, and clinical symptoms reduce 50%, does not have new hair to burst
Ulcer.
3rd, treatment recovery from illness：Ulcer is painless, ulcer surface healing, clinical symptom disappearance, does not there is new hair ulcer.
Therapeutic scheme：
Treatment group：Affected part uses external preparation 4-5 times daily, and continuous use is observed once for a course for the treatment of further consultation on the 4th, totally 2
The course for the treatment of；
Control group：Compound chlorhexidine gargle, 2 times a day；Compound eupatorium syrup, 3 times a day, the same treatment group for the treatment of time；
Obtain following clinical data：
| Illness | After treatment | It is efficient | Cure rate | Use embodiment |
| The people for the treatment of group 25 | 11 symptoms are effective；14 symptom recoveries from illness | 100% | 56% | Embodiment 1 |
| The people for the treatment of group 25 | 12 symptoms are effective；12 symptom recoveries from illness | 96% | 48% | Embodiment 2 |
| The people of control group 26 | 11 symptoms are effective；8 symptom recoveries from illness | 73% | 31% | - |
Clinical test shows：Yao nationality medicine external pulvis of the present invention has significant curative effect to canker sore, efficient close to 100%, and subsequently
Further consultation finds no new hair ulcer and produced.
Model case：
It is the model case using Yao nationality medicine external pulvis treatment canker sore below:
Embodiment 1：Lee, man, Laibin, Guangxi Province people, 24 years old, because of edible excessive barbecue, fried food, drink beyond one's capacity, it is raw on the inside of lip
Go out ulcer at 3, pain is red and swollen at ulcer, goes to examination in hospital for canker sore caused by excessive internal heat, then using the embodiment of the present invention 1
Powder is treated, daily to use 4-5 time, has been feels pain sense disappearance when just using, after 3 days, ulcer surface base
This recovery from illness.
Embodiment 2：Tang, female, people from Liuzhou, 34 years old, have a fever after catching a cold 2 days, suffer from canker sore at 2, gum redness,
At gum at ulcer 1, go to examination in hospital for canker sore caused by passive protective physical fitness decline, then using the embodiment of the present invention 2
Powder is treated, daily to use 4-5 times, after 3 days, ulcer recovery from illness.
Embodiment 3：Yuan, man, Guangxi Gold show people, 45 years old, canker sore recurrent exerbation was had a surplus for 3 months, every time from enforcement
To be treated with watermelon crystal spray, pain is alleviated in therapeutic process, but still fails to cure completely, while with having sore throat,
It is canker sore caused by bacterium infection to go to examination in hospital, is then treated using the powder of the embodiment of the present invention 2, daily to use
4-5 times, after 7 days, ulcer surface is largely fully recovered, and has no new hair ulcer, is treated to after 12 days, ulcer recovery from illness,
And further consultation no relapse after one month.
Embodiment 4：Xiao, man, Laibin, Guangxi Province people, 42 years old, at tongue canker sore two, and feel breathes hard, the traditional Chinese medical science
Check as insufficiency of the spleen canker sore, thick libngual fur, then treated using the powder of the embodiment of the present invention 1, it is daily to use 3 times, add
Eat some invigorating the spleen decoction of medicinal ingredients, after 7 days, ulcer recovery from illness.
Claims (2)
1. a kind of Yao nationality medicine external pulvis for treating canker sore, it is characterised in that by the herbal raw material system of following weight proportion
Into：Hairy euphorbia 8-10 parts, sour rattan root 3-5 parts, goldenrod 3-5 parts, blank sheet of paper fan 2-3 parts；Obtained medicine composition is outer
Use powder.
2. the Yao nationality medicine external pulvis for the treatment of canker sore as claimed in claim 1, it is characterised in that：The preparation method of powder is such as
Under：
Hairy euphorbia, sour rattan root, goldenrod and blank sheet of paper fan are taken by weight ratio, by raw material drying, are then fed into medicinal herb grinder
Middle attrition grinding, after be mixed evenly, cross 100-120 mesh sieves, obtain fine powder and be placed in microwave dryer and sterilized, you can bottling
Obtain finished product external pulvis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711002578.0A CN107823293B (en) | 2017-10-24 | 2017-10-24 | Yao medicine external powder for treating oral ulcer and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711002578.0A CN107823293B (en) | 2017-10-24 | 2017-10-24 | Yao medicine external powder for treating oral ulcer and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107823293A true CN107823293A (en) | 2018-03-23 |
| CN107823293B CN107823293B (en) | 2020-12-04 |
Family
ID=61649069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711002578.0A Active CN107823293B (en) | 2017-10-24 | 2017-10-24 | Yao medicine external powder for treating oral ulcer and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107823293B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109222533A (en) * | 2018-09-17 | 2019-01-18 | 金秀瑶族自治县瑶医医院 | Tranquilizing the mind precious jade medicine medicine-filled pillow and preparation method thereof |
| CN115463067A (en) * | 2022-10-24 | 2022-12-13 | 上海咏旭生物科技有限公司 | Oral care composition containing climbing groundsel herb extract and erigeron breviscapus extract and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784847A (en) * | 2014-01-09 | 2014-05-14 | 山东省立医院 | External powder for treating dental ulcer |
-
2017
- 2017-10-24 CN CN201711002578.0A patent/CN107823293B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784847A (en) * | 2014-01-09 | 2014-05-14 | 山东省立医院 | External powder for treating dental ulcer |
Non-Patent Citations (2)
| Title |
|---|
| 程金生等: "《客家中草药图鉴及民间验方》", 31 August 2016 * |
| 范文昌等: "《广东地产清热解毒药物大全》", 31 July 2011 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109222533A (en) * | 2018-09-17 | 2019-01-18 | 金秀瑶族自治县瑶医医院 | Tranquilizing the mind precious jade medicine medicine-filled pillow and preparation method thereof |
| CN115463067A (en) * | 2022-10-24 | 2022-12-13 | 上海咏旭生物科技有限公司 | Oral care composition containing climbing groundsel herb extract and erigeron breviscapus extract and application thereof |
| CN115463067B (en) * | 2022-10-24 | 2023-12-12 | 上海咏旭生物科技有限公司 | Oral care composition containing senecio scandens extract and erigeron breviscapus extract and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107823293B (en) | 2020-12-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103520655B (en) | Traditional Chinese medicine composition for treating psoriasis vulgaris and preparation method thereof | |
| CN103239662A (en) | Parasite expelling Chinese herbal preparation for animals | |
| CN107823293A (en) | Treat Yao nationality medicine external pulvis of canker sore and preparation method thereof | |
| CN104001045A (en) | Drug for treating dog pneumonia and preparation method thereof | |
| CN103859373A (en) | Formula and preparation method of life cultivation and health preservation food helpful for preserving health during menstrual period | |
| CN110916036A (en) | A kind of wine dew and preparation method thereof | |
| CN102205022B (en) | Chinese medicinal preparation for treating mycotic infection and preparation method thereof | |
| CN104738754A (en) | Drink for moistening lung to arrest cough and production method thereof | |
| CN108938920A (en) | A kind of Huang ground building wine and preparation method thereof | |
| CN114404517A (en) | Composition for gout and reducing uric acid and application and preparation method thereof | |
| CN112494614A (en) | Chinese medicinal formula for preventing and treating cancer by using combination of pawpaw and various medicines | |
| CN111084878A (en) | Biological medicine and medical total nutrient food for lung and respiratory system diseases and preparation method thereof | |
| CN104353043A (en) | Traditional Chinese medicine composition for treating dawn diarrhea and preparation method thereof | |
| CN115006491B (en) | Traditional Chinese medicine composition for treating chronic atrophic gastritis and preparation method thereof | |
| CN106620397A (en) | Granules capable of preventing and treating dental ulcer and preparation method of granules | |
| CN106880758A (en) | It is a kind of for pruritus vulvue and the Chinese medicine preparation and preparation method of eczema stubborn dermatitis | |
| CN105963533A (en) | Preparation method of traditional Chinese medicine for treating chronic pharyngitis and traditional Chinese medicine buccal tablet | |
| CN106039075A (en) | Traditional Chinese medicine composition and method for treating lung and stomach heat accumulated type chronic pharyngitis | |
| CN104888172B (en) | Treat ginger green onion cough arresting and the application of allergic cough | |
| CN104687194A (en) | Heat-clearing, phlegm-dissipating and cough-relieving beverage and preparation method thereof | |
| CN115671165A (en) | Gastrointestinal detoxification powder and preparation method thereof | |
| CN104825846A (en) | A kind of traditional Chinese medicine composition for treating facial neuritis | |
| CN116196361A (en) | A Chinese medicinal health product and its preparation method | |
| CN105497556A (en) | Fresh living herbal internally and externally-used health care medicinal liquor | |
| CN111529658A (en) | A kind of ointment for treating rotavirus enteritis and preparation method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |