CN116196350A - Traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer - Google Patents
Traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer Download PDFInfo
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- CN116196350A CN116196350A CN202310381067.3A CN202310381067A CN116196350A CN 116196350 A CN116196350 A CN 116196350A CN 202310381067 A CN202310381067 A CN 202310381067A CN 116196350 A CN116196350 A CN 116196350A
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- ulcerative colitis
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- peptic ulcer
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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Abstract
The invention relates to a traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer. Mainly solves the problems of poor treatment effect and frequent recurrence of the traditional Chinese and western medicines. The method is characterized in that: the components are as follows: fructus crataegi, semen Juglandis, radix astragali, glycyrrhrizae radix, and Atractylodis rhizoma; the weight portion ratio of each component is as follows: 20-40 parts of fructus lycii, 20-50 parts of walnut, 20-30 parts of astragalus, 10-20 parts of liquorice and 20-30 parts of bighead atractylodes rhizome. The traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer can treat diseases such as ulcerative colitis, peptic ulcer, gastritis and the like, has obvious curative effect, quick response, no recurrence and short treatment period, and is the optimal medicament for treating ulcerative colitis and peptic ulcer at present.
Description
Technical field:
the invention relates to the technical field of Chinese herbal medicine preparations, in particular to a Chinese herbal medicine combination preparation for treating ulcerative colitis and peptic ulcer.
The background technology is as follows:
ulcerative colitis and peptic ulcers are common diseases of the digestive system. Ulcerative colitis is a chronic inflammation, the lesions are mainly in the inner colon membrane, mainly ulcerations and erosions, often occurring in the distal colorectal and sigmoid colon, and can progress gradually toward the proximal end of the colon or even involve the entire colon. Mainly abdominal pain, diarrhea, and fecal mixed with mucopurulent blood and rectal depression. Individuals may also simply present with dry stool, difficult bowel movements, ages 20 to 40 years old. The pathogenesis of traditional Chinese medicine is caused by improper diet, damp-heat, blood stasis, spleen deficiency, failure of health care and qi-blood disharmony. Peptic ulcers, which are inflammatory and necrotic lesions of the mucosa under the action of various causative agents, are diseases that deepen up to the mucosal myolayer, often occur in the mucosa of the digestive tract involved in gastric secretion, with the gastroduodenal being the most common. The pathogenesis of the traditional Chinese medicine is that peptic ulcer belongs to stomachache, and can be accompanied with symptoms such as abdominal distension, acid regurgitation, nausea, vomiting or loose stool, hypodynamia and the like.
At present, ulcerative colitis and peptic ulcer are usually treated by adopting two methods of traditional Chinese medicine and western medicine. The traditional Chinese medicines such as dragon's blood, first bead, bletilla striata, chinese gall, alum and the like are applied to the traditional Chinese medicine composition for general use, and the traditional Chinese medicines are orally taken and enema also achieve some effects, but the disadvantage is that the traditional Chinese medicines can relapse. Western medicines are gentamicin and dexamethasone for clysis treatment, and the treatment method of dexamethasone is adopted, so that the medicine is well absorbed at the moment, but the long-term effect is poor, the medicine can relapse, and the medicine of the Demi hormone can produce necrosis on the femoral head to cause injury.
The invention comprises the following steps:
the invention aims to overcome the problems of poor long-term effect and frequent recurrence of the existing treatment by adopting Chinese and western medicines in the background technology, and provides a traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer. The traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer can treat, condition and repair ulcerative colitis and peptic ulcer diseases, has obvious curative effect, obvious effect and short treatment course, and is not easy to relapse.
The invention solves the problems by the following technical proposal: a Chinese medicinal composition for treating ulcerative colitis and peptic ulcer comprises the following medicinal components: fructus crataegi, semen Juglandis, radix astragali, glycyrrhrizae radix, and Atractylodis rhizoma; the weight portion ratio of each component is as follows: 20-40 parts of fructus lycii, 20-50 parts of walnut, 20-30 parts of astragalus, 10-20 parts of liquorice and 20-30 parts of bighead atractylodes rhizome.
Preferably, the mountain red is wild mountain red.
Preferably, the hickory nut is a wild hickory nut.
Preferably, the mountain red is 2-7 days before the August.
Preferably, the hickory, the astragalus, the liquorice and the bighead atractylodes rhizome are picked in the current year.
The invention provides a preparation method of a traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer, which comprises the following steps: mixing fructus crataegi, fructus Juglandis Immaturus, radix astragali, glycyrrhrizae radix, and Atractylodis rhizoma together according to a certain proportion, pulverizing, adding 50% (v/v) red jowar wine, soaking, and sealing for 30 days; filtering to obtain medicinal liquid.
Preferably, the weight of the red sorghum liquor added is 2 times of the total sum of 5 components of the Chinese hawthorn, the hickory nut, the astragalus root, the liquorice and the bighead atractylodes rhizome.
The traditional Chinese medicine composite preparation for treating ulcerative colitis and peptic ulcer adopts the following components in the formula:
the wild fructus crataegi, also called fructus crataegi, has effects and actions of: the fructus crataegi has effects of stimulating appetite, resolving food stagnation, promoting blood circulation, removing blood stasis, astringing, and relieving dysentery. The fruit of the Chinese hawthorn is sweet and sour, is edible and medicinal from old times, has sweet and sour taste and slightly warm nature, enters spleen, stomach and liver channels, and is commonly used for dyspepsia, achlorhydria, abdominal pain, diarrhea, dysentery, chronic colitis, gastrorrhagia and the like.
The wild walnut contains a large amount of antioxidants, oleic acid and arginine, and the three substances can protect the cardiovascular system after entering the human body; walnut is sweet in flavor, warm in nature, enters kidney and large intestine meridian, can tonify kidney, moisten intestine to relieve constipation, kill parasites, and has certain effects of excreting dampness and healing sores and ulcers.
The efficacy of the astragalus membranaceus is as follows: has effects in invigorating spleen, replenishing qi, consolidating superficial resistance, relieving sweating, invigorating spleen, tonifying lung, promoting urination, consolidating superficial resistance, removing toxic substances, healing sore, and promoting granulation; can be used for treating edema due to qi deficiency, blood deficiency, suppurative sore, debilitation, chronic diarrhea, chronic dysentery, rectocele, hematochezia, and metrorrhagia.
Efficacy of the licorice: tonifying qi and spleen, relieving pain, and promoting the heart, spleen and stomach meridians, it is effective for spleen and stomach weakness, debilitation, and weakness, and is a harmonizing agent and booster of various traditional Chinese medicines.
Efficacy of the bighead atractylodes rhizome: preventing ulcerative colitis and peptic ulcer, improving immunity, removing toxic substances, regulating spleen and stomach, resisting oxidation, promoting gastrointestinal peristalsis, improving digestion, and eliminating pathogenic bacteria in stomach; improving spleen and stomach functions.
The red sorghum produced in northeast has the effects of: cooling blood, removing toxic substances, invigorating spleen, regulating stomach function, warming spleen and stomach, and relieving diarrhea. The red sorghum is brewed into white spirit, and the essence is taken to be soaked and matched with other medicines.
The five combined medicines and foods are dual-purpose, and have no pesticides and fertilizers, so the five combined medicines and foods have no pollution and belong to green products. The preparation process is simple, the treatment method is simple and convenient, and the green treatment is beneficial to conditioning and treating ulcerative colitis, peptic ulcer and other diseases.
The picking time of the wild fructus crataegi is preferably limited to 2-7 days before the August, the fruits are ripe and full, the components are not lost, and the fruits are picked and stoned for processing.
The wild walnut is preferably new walnut picked from the tree in the current year, and is prepared into powder by repeatedly cleaning, removing stains, naturally drying in the sun.
The three medicines and foods of astragalus, liquorice and bighead atractylodes rhizome are preferably picked in the same year.
The preparation process of the liquid medicine for treating ulcerative colitis and peptic ulcer inflammation comprises the following steps: the five medicinal and edible materials of the Chinese hawthorn, the hickory, the astragalus, the liquorice and the bighead atractylodes rhizome are weighed accurately according to the proportion, then are prepared into powder together, and are soaked in 50-degree red sorghum liquor in northeast for 10 days, and the liquid medicine is obtained after filtration, so that the Chinese hawthorn wine can be used.
The five material combinations can greatly enhance the strength of various cooperations and cooperations after being infused, can effectively treat and regulate ulcerative colitis and peptic ulcer, and can be treated by oral administration and rectal infusion. The drip is to insert the drip tube into the rectum for about 20 cm and slowly drip into the intestinal cavity. The direct administration has better effect and better absorption.
The invention is used for treating, conditioning, repairing, ulcerative colitis and peptic ulcer diseases, and has obvious curative effect. The medicament of the invention also has curative effect on proctitis and gastritis.
The traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer comprises the following steps of: twice daily, taking 8 ml orally before each meal; rectal infusion method: once daily, the heavy people can drop twice, 30 milliliters each time, 50 milliliters each time. The medicine liquid for treating ulcerative colitis and peptic ulcer has the cure rate of more than 99% after more than ten years of treatment, conditioning and repairing of 360 cases.
Compared with the background technology, the invention has the following beneficial effects:
the Chinese medicinal preparation for treating ulcerative colitis and peptic ulcer is prepared from five medicinal and edible materials of wild fructus crataegi, wild hickory, radix astragali, atractylodis rhizoma and Glycyrrhrizae radix by pulverizing, and mixing with red jowar wine for treating, coordinating and repairing ulcerative colitis and peptic ulcer. Over ten years, 360 cases of treatment, conditioning and repair are treated, and the cure rate is over 99 percent. At the same time, no recurrent cases appear. The treatment effect is obvious. The medicine is orally taken and rectally drip-administered, and the rectal administration directly reaches the focus, so that the effect is more ideal. The Chinese medicinal composition preparation also has the curative effect of treating proctitis and gastritis.
The specific embodiment is as follows:
the invention is further described in connection with the following embodiments:
example 1
Weighing 20 g of wild Chinese hawthorn, 20 g of hickory nut, 20 g of astragalus, 10 g of liquorice and 20 g of bighead atractylodes rhizome, putting into a container, grinding into powder, mixing to obtain powder, pouring 180 g of 50-degree red sorghum liquor in northeast China, sealing and soaking for 30 days, and filtering to obtain a liquid medicine for use.
Example 2
Weighing 40 g of Chinese hawthorn, 50 g of hickory, 30 g of astragalus, 20 g of liquorice and 30 g of bighead atractylodes rhizome, putting into a container, grinding into powder, mixing to prepare powder, pouring 340 g of 50-degree red sorghum liquor in northeast China, sealing and soaking for 30 days, and filtering to obtain a liquid medicine for use.
Example 3
Weighing 30 g of Chinese hawthorn, 35 g of hickory nut, 25 g of astragalus, 15 g of liquorice and 25 g of bighead atractylodes rhizome, putting into a container, grinding into powder, mixing to prepare powder, pouring 260 g of 50-degree red sorghum liquor in northeast China, sealing and soaking for 30 days, and filtering to obtain a liquid medicine for use.
Example 4
Weighing 35 g of Chinese hawthorn, 40 g of hickory, 30 g of astragalus, 18 g of liquorice and 26 g of bighead atractylodes rhizome, putting into a container, grinding into powder, mixing, pouring 298 g of 50-degree red sorghum liquor in northeast, sealing and soaking for 30 days, and filtering to obtain a liquid medicine for use.
Example 5
Weighing 20 g of Chinese hawthorn, 20 g of hickory nut, 20 g of astragalus, 20 g of liquorice and 20 g of bighead atractylodes rhizome, putting into a container, grinding into powder, pulverizing together, pouring 200 g of 50-degree red sorghum liquor in northeast China, sealing and soaking for 30 days, and filtering to obtain a liquid medicine for use.
In the above examples 1 to 5, the various raw materials used in the present invention are commercially available or can be prepared by a known method unless otherwise specified.
The experience case is as follows:
case 1:
a certain woman, 38 years old, a teacher in primary school, lives in Daqing city and diagnoses ulcerative colitis. The patient has diarrhea for ten times from morning to evening, abdominal pain, bloody pus, obvious emaciation, and no cure from 10 months 1995 to medical treatment everywhere after suffering from the illness. The medicine liquid prepared by the invention is obviously lightened after only half a month by adopting rectal drop therapy, diarrhea is only 2 to 3 times per day after one month, abdominal pain is also better, the bowel movement is normal after 3 months, abdominal pain symptoms disappear, and the weight is also increased slowly. No recurrence occurred for 6 years following the visit.
Case 2:
some field, men, 46 years old, junhe city in south haar sentry area, for many years, ulcerative colitis, diarrhea, abdominal pain, and chronic treatment due to esophageal reflux; the oral administration of the liquid medicine of the invention and the rectal drops can be improved for only one month, and the symptoms are relieved. After 2 months of treatment, abdominal pain is improved, and diarrhea is recovered from the original diarrhea for a plurality of times every day to once every day. No recurrence was observed for 5 years following the visit.
Case 3:
in the urban area of Heilongjiang province, a woman, 48 years old, is diagnosed with peptic ulcer disease, epigastric discomfort, satiation burning pain, no obvious symptoms of dyspepsia such as rhythmicity, heavier eating, inappetence, acid regurgitation, nausea and the like, and the traditional Chinese medicine treatment is not cured in many cases. The medicine liquid disclosed by the invention is orally taken for treating the symptoms of one month, the symptoms disappear, the pain is disappeared, the pain is not felt after eating, and the symptoms of acid regurgitation and nausea are not generated. No recurrence was seen for four years following the visit.
Claims (8)
1. A traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer is characterized in that: the components are as follows: fructus crataegi, semen Juglandis, radix astragali, glycyrrhrizae radix, and Atractylodis rhizoma; the weight portion ratio of each component is as follows: 20-40 parts of fructus lycii, 20-50 parts of walnut, 20-30 parts of astragalus, 10-20 parts of liquorice and 20-30 parts of bighead atractylodes rhizome.
2. A liquid medicine for treating ulcerative colitis and peptic ulcer according to claim 1, wherein: the fructus crataegi is wild fructus crataegi.
3. A liquid medicine for treating ulcerative colitis and peptic ulcer according to claim 1, wherein: the hickory nut is wild hickory nut.
4. The traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer according to claim 2, wherein the traditional Chinese medicine combination preparation is characterized in that: the said fructus crataegi is the picking time before the August.
5. The traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer according to claim 4, wherein the traditional Chinese medicine combination preparation is characterized in that: the fructus crataegi is 2-7 days before the August.
6. The traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer according to claim 1, wherein the traditional Chinese medicine combination preparation is characterized in that: hickory nut, astragalus root, licorice, white atractylodes rhizome are picked in the current year.
7. A method for preparing a traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer according to any one of claims 1 to 6, wherein: the method comprises the following steps: mixing fructus crataegi, fructus Juglandis Immaturus, radix astragali, glycyrrhrizae radix, and Atractylodis rhizoma together according to a certain proportion, pulverizing, adding 50% (v/v) red jowar wine, soaking, and sealing for 30 days; filtering to obtain medicinal liquid.
8. The method for preparing the traditional Chinese medicine combination preparation for treating ulcerative colitis and peptic ulcer according to claim 7, wherein the method is characterized in that: the weight of the red sorghum liquor added is 2 times of the total sum of 5 components of the Chinese hawthorn, the hickory nut, the astragalus root, the liquorice and the bighead atractylodes rhizome.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1579411A (en) * | 2004-05-21 | 2005-02-16 | 广州中医药大学 | Medicine for treating gastrointestinal tract membrana pathology and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1579411A (en) * | 2004-05-21 | 2005-02-16 | 广州中医药大学 | Medicine for treating gastrointestinal tract membrana pathology and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 戴明耀: "蜂蜜治溃疡性胃炎有效", 《蜜蜂杂志》, no. 3, pages 7 * |
| 王桂芳等: "山楂饮灌胃联合愈疡生新方灌肠对小鼠UC的治疗作用", 《中国实验方剂学杂志》, vol. 17, no. 5, pages 193 - 196 * |
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