CN104547749A - Traditional Chinese medicine composition for treating lung cancer and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating lung cancer and preparation method of traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating lung cancer. The traditional Chinese medicine composition is prepared from the following main raw materials in parts by weight: 3-9 parts of stachys geobombycis, 15-30 parts of common dysosmatis rhizome and root, 10-30 parts of herb or fruits of little groundcherry, 3-9 parts of Japonese pearlwort herb, 3-10 parts of radix angelicae pubescentis, 15-30 parts of medical stone, 15-30 parts of natural indigo, 10-20 parts of bitter orange, 10-20 parts of common lophatherum herb, 5-9 parts of epimedium herb, 3-6 parts of coix seeds, 3-15 parts of fructus forsythiae, 15-40 parts of chicken's gizzard-membrane, 10-30 parts of spreading hedyotis herb and 10-30 parts of milkvetch root. The traditional Chinese medicine composition has a significant effect for the lung cancer and has not only the effects of relieving cancer pain and treating cough, but also the anti-cancer and anti-tumor effects. The traditional Chinese medicine composition disclosed by the invention is mainly prepared by selecting local common medicinal materials, the price is low, and the economic burden on a patient is relieved.
Description
Technical field
The invention discloses one and treat pulmonary carcinoma Chinese medicine composition, especially a kind of Chinese medicine composition for the treatment of pulmonary carcinoma and preparation method thereof, the invention belongs to traditional Chinese medicine field.
Background technology
It is the fastest that pulmonary carcinoma is that M & M increases, to one of population health and the maximum malignant tumor of life threat.The many countries of immediate and mid-term all report that the M & M of pulmonary carcinoma all obviously increases, and male lung cancer M & M all accounts for first of all malignant tumor, and women's sickness rate accounts for second, and mortality rate accounts for second.The cause of disease of pulmonary carcinoma is still not exclusively clear and definite so far, and great mass of data shows, long-term a large amount of smoking and pulmonary carcinoma have very close relationship.Existing research proves: the probability that long-term a large amount of smoker suffers from pulmonary carcinoma is 10 ~ 20 times of non-smoker, and the age starting smoking is less, and the probability of suffering from pulmonary carcinoma is higher.In addition, smoking not only directly affects my healthy, also produces harmful effect to the health of surrounding population, causes involuntary smoker's pulmonary carcinoma prevalence obviously to increase.The sickness rate of urbanite's pulmonary carcinoma is higher than rural area, and this may be relevant containing carcinogen with urban atmospheric pollution and flue dust.Therefore should advocate non-smoking, and strengthen city environmental hygiene work.
The cause of disease: 1. smoking: think that smoking is the most important high risk factor of pulmonary carcinoma at present, have more than 3000 kinds of chemical substances in Nicotiana tabacum L., wherein multichain compound fragrant hydrocarbon (as: benzopyrene) and nitrosamine all have very strong carcinogenic activity.Multichain compound fragrant hydrocarbon and nitrosamine cause bronchial epithelial cell DNA damage by number of mechanisms, make oncogene (as Ras gene) activation and antioncogene (as p53, FHIT gene etc.) inactivation, and then cause transformation, final canceration.2. occupation and environmental exposure: pulmonary carcinoma is most important one in occupational cancer.The patients with lung cancer estimating about 10% has environment and Exposed history.Now prove that following 9 kinds of occupational environment carcinogens increase the incidence rate of pulmonary carcinoma: the side-product of aluminum products, arsenic, asbestos, bis-chloromethylether, chromium compound, coke-fired furnace, mustard gas, nickeliferous impurity, vinyl chloride.The materials such as Long Term Contact beryllium, cadmium, silicon, formalin also can increase the sickness rate of pulmonary carcinoma, and air pollution, particularly industrial waste gas all can be lung cancer caused.3. ionizing radiation: lungs are organs comparatively responsive to lonizing radiation.Ionizing radiation causes the data of initial evidence from Schneeberg-joakimov mine of pulmonary carcinoma, and in this mine air, Radon and its descendants concentration is high, and mostly that brings out is bronchial small cell carcinoma.The U.S. once had the miner 70% ~ 80% of report exploitation atomic ore to die from radioactive occupational lung cancer, based on scale cancer, to touch disease time be 10 ~ 45 years, average time is 25 years, and average age of onset is 38 years old.Radon and its descendants by amount accumulation more than 120 working water on ordinary days (WLM) time sickness rate start to increase, more than 1800WLM then significantly increase reach 20 ~ 30 times.In gas mice being exposed to these mines and dust, lung tumor can be brought out.Suffer from pulmonary carcinoma person in Japan Atomic bullet blast survivor significantly to increase.Beebe finds when following up a case by regular visits to all the life hiroshima bomb blast survivor, and the survivor being less than 1400m apart from the quick-fried heart is compared with apart from the survivor beyond the quick-fried heart 1400 ~ 1900m and 2000m, and it dies from pulmonary carcinoma person obviously increases.4. previously pulmonary's chronic infection: as the patient such as pulmonary tuberculosis, bronchiectasis, bronchiolar epithelium may be changed in chronic infection process rawly causes canceration for squamous epithelial cancer, but comparatively rare.5. the factor such as heredity: Familial aggregation, genetic predisposition and immunologic function reduce, and metabolism, endocrine function imbalance etc. also may play an important role in the generation of pulmonary carcinoma.Much research proves, inherited genetic factors may play an important role in the crowd of environmental carcinogen susceptible and/or individuality.6. atmospheric pollution: the sickness rate of developed country's pulmonary carcinoma is high, main cause is due to industry and traffic developed regions, oil, and what produce with bituminous highway dust after coal burns with internal combustion engine etc. is relevant containing harmful substance atmosphere pollutions such as the carcinogenic hydrocarbon of benzopyrene.Atmospheric pollution and smoking may promote mutually the sickness rate of pulmonary carcinoma, play synergism.
Authorization Notice No. CN 103191268 B (application number 201310155086.0) patent discloses a kind of Chinese medicine composition for the treatment of pulmonary carcinoma, it is characterized in that being made up of the Chinese medicine material of following weight portion: Stachys geobombycis C. Y. Wu 15 parts, Ganoderma 12 parts, Radix Tripterygii Wilfordii 12 parts, Radix Ginseng 10 parts, Rhizoma Acori Calami 10 parts, Squama Manis 10 parts, Herba Andrographis 10 parts, Radix Angelicae Sinensis 12 parts and 10 parts, Radix Glycyrrhizae.Authorization Notice No. CN 102940829 B (application number 201210476145.X) patent discloses a kind of Chinese medicine composition for the treatment of pulmonary carcinoma, it is characterized in that, it is made up of the crude drug of following weight: Radix Astragali 20g, Radix et Rhizoma Dysosmatis 20g, Fructus Akebiae 15g, Bulbus Fritillariae Cirrhosae 15g, Indigo Naturalis 10g, Poria 10g, Bulbus Lilii 10g, Radix Platycodonis 10g, Herba Houttuyniae 10g, Gekko Swinhonis 10g, Cordyceps 9g, Hirudo 9g, Radix Stemonae 9g, Bungarus Parvus 3g, Radix Glehniae 3g, Semen Coicis 3g.
Summary of the invention
Along with the development of Chinese Chinese medicine, in Cure and control pulmonary carcinoma, people gradually appreciate treatment by Chinese herbs lung cancer treatment procedure and have no side effect, patient bears painful little, and the advantage that cost is saved relatively, for the present situation of existing western medical treatment cancer, an object of the present invention is the Chinese medicine composition providing a kind of Therapeutic cancer, there is feature easy to operate, evident in efficacy, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a Chinese medicine composition for pulmonary carcinoma, take off the primary raw material stating weight proportion and be prepared from: Stachys geobombycis C. Y. Wu 3-9 part, Radix et Rhizoma Dysosmatis 15-30 part, Herba seu Fructus Physalis Minimae 10-30 part, Herba Saginae Japonicae 3-9 part, Radix Angelicae Pubescentis 3-10 part, Maifanitum 15-30 part, Indigo Naturalis 15-30 part, Fructus Aurantii 10-20 part, Herba Lophatheri 10-20 part, Herba Epimedii 5-9 part, Semen Coicis 3-6 part, Fructus Forsythiae 3-15 part, Endothelium Corneum Gigeriae Galli 15-40 part, Herba Hedyotidis Diffusae 10-30 part, Radix Astragali 10-30 part.
Treat a Chinese medicine composition for pulmonary carcinoma, preferred scheme, take off the primary raw material stating weight proportion and be prepared from: Stachys geobombycis C. Y. Wu 5-9 part, Radix et Rhizoma Dysosmatis 16-25 part, Herba seu Fructus Physalis Minimae 15-25 part, Herba Saginae Japonicae 4-8 part, Radix Angelicae Pubescentis 4-8 part, Maifanitum 18-28 part, Indigo Naturalis 18-25 part, Fructus Aurantii 12-18 part, Herba Lophatheri 14-18 part, Herba Epimedii 6-8 part, Semen Coicis 3.5-5 part, Fructus Forsythiae 6-14 part, Endothelium Corneum Gigeriae Galli 20-38 part, Herba Hedyotidis Diffusae 15-28 part, Radix Astragali 12-28 part.
Treat a Chinese medicine composition for pulmonary carcinoma, better preferred scheme, take off the primary raw material stating weight proportion and be prepared from: Stachys geobombycis C. Y. Wu 8 parts, Radix et Rhizoma Dysosmatis 20 parts, Herba seu Fructus Physalis Minimae 20 parts, Herba Saginae Japonicae 6 parts, Radix Angelicae Pubescentis 5 parts, Maifanitum 20 parts, Indigo Naturalis 20 parts, Fructus Aurantii 15 parts, Herba Lophatheri 15 parts, Herba Epimedii 7 parts, Semen Coicis 4 parts, Fructus Forsythiae 12 parts, Endothelium Corneum Gigeriae Galli 30 parts, Herba Hedyotidis Diffusae 25 parts, the Radix Astragali 15 parts.
Another object of the present invention is just to provide the preparation method of above-mentioned treatment pulmonary carcinoma.
Treat a preparation method for the Chinese medicine composition of pulmonary carcinoma, be prepared from primarily of following step:
1. be placed in clean container by Sal, add the hot water of 70-90 DEG C, instill Oleum sesami after 20-40 minute, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 80-120 mesh sieve;
2. Radix et Rhizoma Dysosmatis, Herba seu Fructus Physalis Minimae and Herba Saginae Japonicae are cleaned, drain away the water, be cut into silk, together be placed in marmite with Stachys geobombycis C. Y. Wu and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 3-6 hour, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 6-12 minute, grind to form smalls with large ferrum spoon, cross 100-140 mesh sieve;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 5-15 minute, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Herba Lophatheri, Herba Epimedii, Semen Coicis, Fructus Forsythiae, Herba Hedyotidis Diffusae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoct 50-70 minute, twice filtrate merges, and leaves standstill 3-5 hour, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 30-50 minute, obtain drying object, drying object is dry at 70-90 DEG C, both obtained according to every part of 10g subpackage.
The preparation method of above-mentioned Chinese medicine composition, 1. step adds the hot water of 75-85 DEG C, instills Oleum sesami (preferred, to add the hot water of 80 DEG C, instill Oleum sesami after 30 minutes) after 25-35 minute.
The preparation method of above-mentioned Chinese medicine composition, 2. step sprays evenly with the yellow wine burning heat, stewing 4-5 hour (preferred, spray evenly with the yellow wine burning heat, stewing 4.5 hours).
The preparation method of above-mentioned Chinese medicine composition, 2. the Chinese crude drug cooked is placed in rapidly in pot by step, parch 8-10 minute (preferred, to be placed in rapidly in pot by the Chinese crude drug cooked, parch 9 minutes).
The preparation method of above-mentioned Chinese medicine composition, 3. the filament cut is placed on and wipes on oily iron plate by step, dries 8-13 minute (preferred, to be placed on by the filament cut and to wipe on oily iron plate, dry 10 minutes).
The preparation method of above-mentioned Chinese medicine composition, step 4. twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoct 55-65 minute (preferred, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 60 minutes).
The preparation method of above-mentioned Chinese medicine composition, 5. thick paste is dried 35-45 minute by step, obtains drying object, by dry at 75-85 DEG C for drying object (preferred, thick paste to be dried 40 minutes, obtain drying object, by drying object drying at 80 DEG C).
This Chinese medicine composition, to pulmonary carcinoma Be very effective, not only has effect of only cancer pain, also has anticancer antineoplastic action.The local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The pharmacological effect of each crude drug is respectively:
Stachys geobombycis C. Y. Wu: call native Cordyceps, white Cordyceps, tapeworm is careless, pulmonary tuberculosis is careless.Flavor efficacy is sweet, flat.The lung moistening of function kidney tonifying, nourishing YIN and supplementing blood, clearing heat and relieving fidgetness.Be applicable to pulmonary tuberculosis cough, deficiency of the lung asthma, haematemesis, night sweat, anemia, infantile malnutrition.
Radix et Rhizoma Dysosmatis: base is former: be the root and rhizome of Berberidaceae Dysosma plant Radix et Rhizoma Dysosmatis, Dysosma Pleiantha and dysosma veitchii Fu.Composition: 1. Radix et Rhizoma Dysosmatis rhizome is containing lignanoid: podophyllotoxin, picropodophyllin; Flavonoid: diphyllin kaempferol, Quercetin etc.2. Dysosma Pleiantha rhizome is containing lignanoid: podophyllotoxin, dehydropodophyllotoxin, podophyllotoxone etc.3. dysosma veitchii Fu root is containing deoxypodophyllotoxin, β-peltain, podophyllotoxin, kaempferol-3-β-D-Glucose glycosides, glucose, sucrose and cupreol.The property of medicine: bitter, pungent, temperature.Poisonous.Return lung, Liver Channel.Function cures mainly: removing toxic substances of reducing phlegm, eliminating stasis and resolving masses.Cure mainly cough, laryngopharynx swelling and pain, scrofula, goiter, nameless gall, herpes zoster, venom, traumatic injury, rheumatic arthralgia.
Herba seu Fructus Physalis Minimae: having another name called husky lantern, sky bubble fruit, the female pearl of king, is herb or the fruit of the little Calyx seu fructus physalis of Solanaceae monkey flower.The property of medicine: bitter in the mouth, cool in nature.Composition: herb examines little physalein etc. containing physagulin, epoxyphysagulin, Wei, containing Palmic acid, stearic acid, oleic acid etc. in seed oil.Find according to modern pharmacological research, this medical instrument has antiinflammatory, anticancer, clearing away heat-damp and promoting diuresis, goes to cough effect of only expectorant, hard masses softening and resolving, for jaundice due to damp-heat, and dysuria, chronic cough and asthma, eczema.
Herba Saginae Japonicae: for being the herb of Caryophyllaceae sagina Herba Saginae Japonicae.Composition: cold volatile oil, the sweet and flavone of soap.Pharmacology: the effect with low anticancer, has antitussive, clears phlegm.The property of medicine: bitter, pungent, cool.Return liver, stomach warp.Function cures mainly: removing pathogenic heat from blood and toxic substance from the body, killing parasites for relieving itching.
Radix Angelicae Pubescentis: be the root of the heavy tooth Radix Angelicae Sinensis of Umbelliferae archangel.Composition: containing coumarin kind compound, volatile oil, acetas, angelol, thymol.Pharmacology: play a very important role to cardiovascular system, has the effect of blood pressure lowering, can promote hematoblastic gathering, have good analgesia and antiinflammatory action.There is anti-light quick effect, have significant curative effect to opposing tumor, anti-inflammation is also played a very important role.The property of medicine: bitter, tepor, pungent.Return kidney, urinary bladder channel.Function cures mainly: expelling wind and dampness, dispersing cold for relieving pain.
Maifanitum: base is former: be Acid-intermediate igneous rock rocks beschtauite.Composition: Maifanitum main component has silicon dioxide, aluminium oxide, ferrum oxide, ferrous oxide, magnesium oxide, calcium oxide, sodium oxide, potassium oxide, titanium dioxide, phosphorus pentoxide, manganese oxide, carbon dioxide, and the trace element such as fluorine, sulfur, strontium, barium, copper, zinc.The property of medicine: " detailed outline ": " sweet, temperature, nontoxic." function cures mainly: removing toxic substances and promoting granulation, damp eliminating spleen invigorating.Cure mainly carbuncle carbuncle on the back, acne, eczema, beriberi, miliaria, finger is chapped, chloasma, toothache, oral ulcer, rheumatic arthralgia, lumbago and backache, chronic hepatitis, gastritis, dysentery, diabetes, neurasthenia, wound is red and swollen, hypertension, senile sclerosis of blood vessels, tumor, lithangiuria.Generally make health product.
Indigo Naturalis: have another name called Concha Meretricis Seu Cyclinae powder, indigo-blue flower, for the leaf of Acanthaceae Acanthaceous indigo platymiscium Acanthaceous indigo, Polygonaceae arsesmart polygonum tinctorium ait., pulse family anil Folium et Caulis Indigoferae Tinctoriae, Cruciferae Isatis indigotica Fort. platymiscium Isatis indigotica Fort. or stem and leaf are through processing obtained dried powder or agglomerate.The property of medicine: this product is navy blue powder, body is light, and easily fly upward, micro-have careless stink smell, salty in the mouth, cold in nature.Composition: its main component has indirubin, indigo.Find according to modern pharmacological research, this medical instrument has effect of antitumor, anti-inflammatory and antalgic, antiulcer, antibacterial, clearing away heat and cooling blood, removing toxic substances, and for the malicious macule of temperature, laryngopharynx swelling and pain, spits blood, epistaxis, the symptoms such as spitting of blood.
Fructus Aurantii: dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.
Herba Lophatheri: Herba Lophatheri has effect of clearing heat and relieving fidgetness, diuresis, be mainly used in treating in the heart disease heat, cough with dyspnea, haematemesis, pyretic toxicity wind, only quench one's thirst, press borax poison, expectorant, control fanatical unhappiness, apoplectic aphasia in silence, pain wind syndrome of head, spasmolytic are throbbed with fear, pestilence fan is vexed, kill small worm, heat extraction delays the diseases such as spleen.
Herba Epimedii: kidney invigorating and YANG supporting, expelling wind and removing dampness.Control sexual impotence erectile problem, hemiplegia is unsuccessful, dribbling urination, and muscles and bones contraction is anxious, and cough, optic atrohic blindness after being ill, toothache caused by fire of deficiency type, hemiplegia, weakness of the waist and knees, rheumatic arthralgia, extremity are meciless.
Semen Coicis: favourable water permeation wets, invigorating the spleen to arrest diarrhea, eliminating impediment, evacuation of pus, the effect of detoxicating and resolving stagnation of pathogens.For edema, beriberi, dysuria, diarrhea due to hypofunction of the spleen, arthralgia chiefly caused by damp pathogen contracture, lung abscess, intestinal carbuncle; Wart, cancerous protuberance.
Fructus Forsythiae: heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.
Endothelium Corneum Gigeriae Galli: sweet is flat.Return spleen, stomach, small intestinal, urinary bladder channel, promoting digestion and invigorating the stomach is aid digestion, arresting seminal emission.Can gastric secretion be promoted, improve gastric acidity and eupepsy, stomach motor function is obviously strengthened, rapid gastric emptying.Arresting seminal emission.Appropriate digested bad, shallow complexion, do not think the condition subject such as Na Gu, infantile malnutrition, emaciated physique, enlarged abdomen abdominal distention, weakness of the spleen and stomach, food stagnation distension, tuberculosis of intestine, bone tuberculosis and eat.
Herba Hedyotidis Diffusae: cure mainly: dyspnea and cough due to lung-heat; Laryngopharynx swelling and pain; Intestinal carbuncle; Furuncle and phyma skin infection; Venom; The puckery pain of pyretic stranguria; Edema; Dysentery; Intestinal is scorching; Jaundice due to damp-heat; Be good at the multiple cancerous protuberance for the treatment of.
The Radix Astragali: the Radix Astragali has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.Jishengshenqiwan albuminuria can be eliminated, strengthen myocardial contraction, regulate blood sugar content.The Radix Astragali can not only coronary artery dilator, improves blood supply of cardiac muscle, improves immunologic function, and can the process of delaying cell aging.
Chinese medicine composition of the present invention debates the principle of disease treatment based on Chinese medicine.Prepared Chinese medicine composition is divided into two, and a for wash open as Orally-administered decoction medicine with hot water, another part Ovum Gallus domesticus album is mixed thoroughly as external is applied ointment or plaster, inside and outside treat simultaneously, treatment is more comprehensive, and affected area administration is rapider, lasting medicine, takes into account inside and outside belonging to, the pulmonary carcinoma prescription for the treatment of both the principal and secondary aspects of a disease.Fabulous therapeutical effect is had, for thin and weak health has fabulous opsonic action because of long-term chemicotherapy to pulmonary carcinoma.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 one kinds treats the Chinese medicine composition of pulmonary carcinoma, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Stachys geobombycis C. Y. Wu 3 parts, Radix et Rhizoma Dysosmatis 15 parts, Herba seu Fructus Physalis Minimae 10 parts, Herba Saginae Japonicae 3 parts, Radix Angelicae Pubescentis 3 parts, Maifanitum 15 parts, Indigo Naturalis 15 parts, Fructus Aurantii 10 parts, Herba Lophatheri 10 parts, Herba Epimedii 5 parts, Semen Coicis 3 parts, Fructus Forsythiae 3 parts, Endothelium Corneum Gigeriae Galli 15 parts, Herba Hedyotidis Diffusae 10 parts, the Radix Astragali 10 parts.
The Chinese medicine composition for the treatment of pulmonary carcinoma, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 70 DEG C, instill Oleum sesami after 20 minutes, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 80 mesh sieves;
2. Radix et Rhizoma Dysosmatis, Herba seu Fructus Physalis Minimae and Herba Saginae Japonicae are cleaned, drain away the water, be cut into silk, together be placed in marmite with Stachys geobombycis C. Y. Wu and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 3 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 6 minutes, grind to form smalls with large ferrum spoon, cross 100 mesh sieves;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 5 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Herba Lophatheri, Herba Epimedii, Semen Coicis, Fructus Forsythiae, Herba Hedyotidis Diffusae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 50 minutes, twice filtrate merges, and leaves standstill 3 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 30 minutes, obtain drying object, drying object is dry at 70 DEG C, both obtained according to every part of 10g subpackage.
Model case one: Liu XX, female, 45 years old, Shenxian County, Liaocheng of Shandong Province Zhang Lou.Symptom: bimester frontly find lung tumors in hospital, doctor is thought of as optimum, require expectant treatment, bimester after check, bimester after institute be pet-ct at me, result shows: bottom right pulmonary carcinoma, and in right side hilus pulumonis and vertical diaphragm, pericardium, after pancreas, peritoneum, paracolic sulci, right side iliac vessels are other fawns on transfer.The subcutaneous multiple nodules shadow of the multiple Bone tumour of whole body, whole body, is thought of as transfer.In whole-body muscle, multiple nodules shape FDG is dense poly-, and be thought of as the multiple muscle transfer of whole body, do not have appetite, lean body mass is weak.Treatment is stopped because standing and hold untoward reaction and high expense that can't stand chemotherapy.
Use and take embodiment 1 resulting composition, compositions is divided into two, a for wash open as Orally-administered decoction medicine with hot water, 2 times on the one, the morning, noon and afternoon take after meal half an hour, and another part is mixed thoroughly with Ovum Gallus domesticus album and is applied in the tsusanli acupoint (two), once a day, use traditional Chinese medicine composition for treating of the present invention 5 days, pain symptom alleviates, and appetite is recovered to some extent; Use traditional Chinese medicine composition for treating of the present invention 4 months, go to hospital to check cancerous cell and substantially do not spread; Use traditional Chinese medicine composition for treating of the present invention 7 months, cancerous cell basic controlling there is not diffusing phenomenon.
Embodiment 2 one kinds treats the Chinese medicine composition of pulmonary carcinoma, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Stachys geobombycis C. Y. Wu 9 parts, Radix et Rhizoma Dysosmatis 30 parts, Herba seu Fructus Physalis Minimae 30 parts, Herba Saginae Japonicae 9 parts, Radix Angelicae Pubescentis 10 parts, Maifanitum 30 parts, Indigo Naturalis 30 parts, Fructus Aurantii 20 parts, Herba Lophatheri 20 parts, Herba Epimedii 9 parts, Semen Coicis 6 parts, Fructus Forsythiae 15 parts, Endothelium Corneum Gigeriae Galli 40 parts, Herba Hedyotidis Diffusae 30 parts, the Radix Astragali 30 parts.
The Chinese medicine composition for the treatment of pulmonary carcinoma, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 90 DEG C, instill Oleum sesami after 40 minutes, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 120 mesh sieves;
2. Radix et Rhizoma Dysosmatis, Herba seu Fructus Physalis Minimae and Herba Saginae Japonicae are cleaned, drain away the water, be cut into silk, together be placed in marmite with Stachys geobombycis C. Y. Wu and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 6 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 12 minutes, grind to form smalls with large ferrum spoon, cross 140 mesh sieves;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 15 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Herba Lophatheri, Herba Epimedii, Semen Coicis, Fructus Forsythiae, Herba Hedyotidis Diffusae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 70 minutes, twice filtrate merges, and leaves standstill 5 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 50 minutes, obtain drying object, drying object is dry at 90 DEG C, both obtained according to every part of 10g subpackage.
Model case two: Lee xx, man, 39 years old, Meng Jia village, Jin Zhuan town, Sishui County, Jining City in Shandong Province.Symptom: the situation occurring cough uncomfortable in chest, left breast dull pain, patient was busy at that time, often went on business and did not also take notice of very much, think indisposition, after 1 month, chest pain does not only slow down, and aggravates on the contrary, once cough is spat, sputum mixed with blood, and patient's self-induction is far from good, remove examination in hospital, be diagnosed as advanced lung cancer through hospital of Jining City, lymph metastasis, chronic cough, the excessive phlegm band blood streak, hydrothorax, chemotherapy is after 1 month, and health holds really be can't stand, hear of Chinese medicine composition curative effect of the present invention fine.
Use and take embodiment 2 resulting composition, compositions is divided into two, a for wash open as Orally-administered decoction medicine with hot water, 2 times on the one, the morning, noon and afternoon take after meal half an hour, another part is mixed thoroughly with Ovum Gallus domesticus album and is applied in the tsusanli acupoint (two), once a day, use traditional Chinese medicine composition for treating of the present invention 10 days, cough alleviates, pain symptom alleviates, and appetite is recovered to some extent; Use traditional Chinese medicine composition for treating of the present invention 5 months, go to hospital to check cancerous cell and substantially do not spread; Use traditional Chinese medicine composition for treating of the present invention 6 months, cancerous cell basic controlling there is not diffusing phenomenon.
Embodiment 3 one kinds treats the Chinese medicine composition of pulmonary carcinoma, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Stachys geobombycis C. Y. Wu 5 parts, Radix et Rhizoma Dysosmatis 16 parts, Herba seu Fructus Physalis Minimae 15 parts, Herba Saginae Japonicae 4 parts, Radix Angelicae Pubescentis 4 parts, Maifanitum 18 parts, Indigo Naturalis 18 parts, Fructus Aurantii 12 parts, Herba Lophatheri 14 parts, Herba Epimedii 6 parts, Semen Coicis 3.5 parts, Fructus Forsythiae 6 parts, Endothelium Corneum Gigeriae Galli 20 parts, Herba Hedyotidis Diffusae 15 parts, the Radix Astragali 12 parts.
The Chinese medicine composition for the treatment of pulmonary carcinoma, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 75 DEG C, instill Oleum sesami after 25 minutes, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 90 mesh sieves;
2. Radix et Rhizoma Dysosmatis, Herba seu Fructus Physalis Minimae and Herba Saginae Japonicae are cleaned, drain away the water, be cut into silk, together be placed in marmite with Stachys geobombycis C. Y. Wu and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 4 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 6 minutes, grind to form smalls with large ferrum spoon, cross 110 mesh sieves;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 8 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Herba Lophatheri, Herba Epimedii, Semen Coicis, Fructus Forsythiae, Herba Hedyotidis Diffusae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 55 minutes, twice filtrate merges, and leaves standstill 3.5 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 35 minutes, obtain drying object, drying object is dry at 75 DEG C, both obtained according to every part of 10g subpackage.
Model case three: poplar xx, female, 50 years old, the Su Han village, Pingdu City Lan Di town, Shandong Province.Symptom: just started to swallow pain obstinate, after with the symptom of deep coughs, spitting of blood, the obvious enlargement of throat, originally think that Cold Dew in autumn, the heavy colour of sky cooled off the flu caused at the beginning, patient goes to hospital to accept treatment according to flu, not only do not take a turn for the better, all the more serious on the contrary, chest pain, cough aggravation.Pulmonary carcinoma in mid-term is diagnosed as through examination in hospital.Sick age: 6 months.Examine the time: in July, 2012.
Use and take embodiment 3 resulting composition, compositions is divided into two, a for wash open as Orally-administered decoction medicine with hot water, 2 times on the one, the morning, noon and afternoon take after meal half an hour, and another part is mixed thoroughly with Ovum Gallus domesticus album and is applied in the tsusanli acupoint (two), once a day, use traditional Chinese medicine composition for treating of the present invention 5 days, cough, pain symptom alleviate, and appetite is recovered to some extent; Use traditional Chinese medicine composition for treating of the present invention 4 months, go to hospital to check cancerous cell and substantially do not spread; Use traditional Chinese medicine composition for treating of the present invention 5 months, cancerous cell basic controlling there is not diffusing phenomenon.
Embodiment 4 one kinds treats the Chinese medicine composition of pulmonary carcinoma, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Stachys geobombycis C. Y. Wu 9 parts, Radix et Rhizoma Dysosmatis 25 parts, Herba seu Fructus Physalis Minimae 25 parts, Herba Saginae Japonicae 8 parts, Radix Angelicae Pubescentis 8 parts, Maifanitum 28 parts, Indigo Naturalis 25 parts, Fructus Aurantii 18 parts, Herba Lophatheri 18 parts, Herba Epimedii 8 parts, Semen Coicis 5 parts, Fructus Forsythiae 14 parts, Endothelium Corneum Gigeriae Galli 38 parts, Herba Hedyotidis Diffusae 28 parts, the Radix Astragali 28 parts.
The Chinese medicine composition for the treatment of pulmonary carcinoma, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 85 DEG C, instill Oleum sesami after 35 minutes, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 110 mesh sieves;
2. Radix et Rhizoma Dysosmatis, Herba seu Fructus Physalis Minimae and Herba Saginae Japonicae are cleaned, drain away the water, be cut into silk, together be placed in marmite with Stachys geobombycis C. Y. Wu and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 5 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 10 minutes, grind to form smalls with large ferrum spoon, cross 130 mesh sieves;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 13 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Herba Lophatheri, Herba Epimedii, Semen Coicis, Fructus Forsythiae, Herba Hedyotidis Diffusae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 65 minutes, twice filtrate merges, and leaves standstill 4.5 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 45 minutes, obtain drying object, drying object is dry at 85 DEG C, both obtained according to every part of 10g subpackage.
Model case four: field xx, man, 44 years old, people from Jiyang County, Jinan City, Shandong Province.Symptom: in December, 2009, originally just cough, and accompany left breast dull pain, after two months, neglect sputum mixed with blood, remove examination in hospital, inferior lobe of left lung adenocarcinoma, after the diagnosis of doctor, allow patient carry out chemotherapy, in the process of chemotherapy, leukocyte, number of platelets decline serious, with stomachache, so patient's refusal accepts chemotherapy, the doctor advised present composition again.
Use and take embodiment 4 resulting composition, compositions is divided into two, a for wash open as Orally-administered decoction medicine with hot water, 2 times on the one, morning, noon and afternoon take after meal half an hour, another part is mixed thoroughly with Ovum Gallus domesticus album and is applied in the tsusanli acupoint (two), once a day, uses traditional Chinese medicine composition for treating of the present invention 15 days, cough, pain symptom alleviate, appetite is recovered to some extent, and muscle power obviously increases, and oneself can get up and arrive outdoor stroll; Use traditional Chinese medicine composition for treating of the present invention 3 months, go to hospital to check cancerous cell and substantially do not spread; Use traditional Chinese medicine composition for treating of the present invention 5 months, cancerous cell does not have change substantially, and body weight increases, and quality of life, mood was more optimistic than originally than there being very large change during western medical treatment, had had new hope to life, in continuing at present to take.
Embodiment 5 one kinds treats the Chinese medicine composition of pulmonary carcinoma, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Stachys geobombycis C. Y. Wu 8 parts, Radix et Rhizoma Dysosmatis 20 parts, Herba seu Fructus Physalis Minimae 20 parts, Herba Saginae Japonicae 6 parts, Radix Angelicae Pubescentis 5 parts, Maifanitum 20 parts, Indigo Naturalis 20 parts, Fructus Aurantii 15 parts, Herba Lophatheri 15 parts, Herba Epimedii 7 parts, Semen Coicis 4 parts, Fructus Forsythiae 12 parts, Endothelium Corneum Gigeriae Galli 30 parts, Herba Hedyotidis Diffusae 25 parts, the Radix Astragali 15 parts.
The Chinese medicine composition for the treatment of pulmonary carcinoma, preparation process is as follows:
1. be placed in clean container by Sal, add the hot water of 80 DEG C, instill Oleum sesami after 30 minutes, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 100 mesh sieves;
2. Radix et Rhizoma Dysosmatis, Herba seu Fructus Physalis Minimae and Herba Saginae Japonicae are cleaned, drain away the water, be cut into silk, together be placed in marmite with Stachys geobombycis C. Y. Wu and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 4.5 hours, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 9 minutes, grind to form smalls with large ferrum spoon, cross 120 mesh sieves;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 10 minutes, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Herba Lophatheri, Herba Epimedii, Semen Coicis, Fructus Forsythiae, Herba Hedyotidis Diffusae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 60 minutes, twice filtrate merges, and leaves standstill 4 hours, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 40 minutes, obtain drying object, drying object is dry at 80 DEG C, both obtained according to every part of 10g subpackage.
Experimental example: clinical data: 1, physical data: be diagnosed as patients with advanced NSCLC through histopathology and cytolgical examination, the age is between 25-70; Important organ function of organization is normal.The patient meeting this research inclusion criteria is 400 examples.
2, diagnostic criteria: Western medicine diagnose standard: specified standard in " Chinese common cancer diagnosis and treatment specification " that Diagnosis of Non-Small Cell Lung standard adopts Department of Medical Administration of Ministry of Health of the People's Republic of China to write.Tcm diagnosis standard: formulate with reference to Ministry of Public Health " new Chinese medicine guideline of clinical investigations " (2002 editions), distinguish as accumulateing disease in ecchymosis: cough, cough up phlegm, expectorant blood, uncomfortable in chest, out of breath, chest pain, expectorant is yellow or expectorant blood is dark red, can with low grade fever, purplish tongue or have petechia, ecchymosis, yellow and thin fur, hesitant pulse or stringy and thready pulse.
3, Therapeutic Method: adopt Chinese medicine composition of the present invention, compositions is divided into two, a for wash open as Orally-administered decoction medicine with hot water, 2 times on the one, morning, noon and afternoon take after meal half an hour, and another part is mixed thoroughly with Ovum Gallus domesticus album and is applied in the tsusanli acupoint (two), once a day.
4, criterion of therapeutical effect: effective: cough, cough up phlegm, expectorant blood, uncomfortable in chest, chest pain, the common sympton such as out of breath, heating alleviate substantially, cancer rill is suppressed, invalid: malaise symptoms is all unchanged.In order to verify the effect of Chinese medicine composition of the present invention, We conducted the experiment (embodiment 5) of medicine, and accurately statistics and mathematical analysis having been carried out to data.
Specific experiment result is as following table:
Table 1:
Table 2:
Prove through clinical trial, use Chinese medicine composition of the present invention compared with the means of western medical treatment cancer, control recurrence rate after healing low, treatment means is more comprehensive thoroughly, have no side effect between the operating period, while treatment pulmonary carcinoma, the symptom such as pain, cough, heating, inappetence brought by pulmonary carcinoma can be alleviated.Prove through clinical trial, Chinese drugs agentia effective percentage of the present invention is 98%, good therapeutical effect is all had for early stage and advanced lung cancer, for Patients with Advanced Lung Cancer, use Chinese medicine composition of the present invention, while effectively controlling cancerous cell high speed diffusion, the quality of life of residue life can be made to improve, increase the confidence for future life.Therefore Chinese medicine composition of the present invention is a kind of medicine for the treatment of pulmonary carcinoma safely and effectively.
Claims (10)
1. treat a Chinese medicine composition for pulmonary carcinoma, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Stachys geobombycis C. Y. Wu 3-9 part, Radix et Rhizoma Dysosmatis 15-30 part, Herba seu Fructus Physalis Minimae 10-30 part, Herba Saginae Japonicae 3-9 part, Radix Angelicae Pubescentis 3-10 part, Maifanitum 15-30 part, Indigo Naturalis 15-30 part, Fructus Aurantii 10-20 part, Herba Lophatheri 10-20 part, Herba Epimedii 5-9 part, Semen Coicis 3-6 part, Fructus Forsythiae 3-15 part, Endothelium Corneum Gigeriae Galli 15-40 part, Herba Hedyotidis Diffusae 10-30 part, Radix Astragali 10-30 part.
2. the Chinese medicine composition for the treatment of pulmonary carcinoma according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Stachys geobombycis C. Y. Wu 5-9 part, Radix et Rhizoma Dysosmatis 16-25 part, Herba seu Fructus Physalis Minimae 15-25 part, Herba Saginae Japonicae 4-8 part, Radix Angelicae Pubescentis 4-8 part, Maifanitum 18-28 part, Indigo Naturalis 18-25 part, Fructus Aurantii 12-18 part, Herba Lophatheri 14-18 part, Herba Epimedii 6-8 part, Semen Coicis 3.5-5 part, Fructus Forsythiae 6-14 part, Endothelium Corneum Gigeriae Galli 20-38 part, Herba Hedyotidis Diffusae 15-28 part, Radix Astragali 12-28 part.
3. the Chinese medicine composition for the treatment of pulmonary carcinoma according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Stachys geobombycis C. Y. Wu 8 parts, Radix et Rhizoma Dysosmatis 20 parts, Herba seu Fructus Physalis Minimae 20 parts, Herba Saginae Japonicae 6 parts, Radix Angelicae Pubescentis 5 parts, Maifanitum 20 parts, Indigo Naturalis 20 parts, Fructus Aurantii 15 parts, Herba Lophatheri 15 parts, Herba Epimedii 7 parts, Semen Coicis 4 parts, Fructus Forsythiae 12 parts, Endothelium Corneum Gigeriae Galli 30 parts, Herba Hedyotidis Diffusae 25 parts, the Radix Astragali 15 parts.
4. the preparation method of the Chinese medicine composition of the treatment pulmonary carcinoma according to any one of claim 1-3, is characterized in that: step is as follows:
1. be placed in clean container by Sal, add the hot water of 70-90 DEG C, instill Oleum sesami after 20-40 minute, take out after being soaked into completely by Maifanitum, it is crisp to be placed in forging on smokeless stove fire, grinds to form smalls, crosses 80-120 mesh sieve;
2. Radix et Rhizoma Dysosmatis, Herba seu Fructus Physalis Minimae and Herba Saginae Japonicae are cleaned, drain away the water, be cut into silk, together be placed in marmite with Stachys geobombycis C. Y. Wu and Fructus Aurantii, spray evenly with the yellow wine burning heat, stewing 3-6 hour, be placed in when food steamer steaming savory blowing out, cease fire, get the hot pot dryouied, add a little Oleum Arachidis hypogaeae semen, when hot pot surrounding has blue or green cigarette to emerge, the Chinese crude drug cooked is placed in rapidly in pot, parch 6-12 minute, grind to form smalls with large ferrum spoon, cross 100-140 mesh sieve;
3. Endothelium Corneum Gigeriae Galli is cleaned, is cut into filament, by tappasaki heat, spread oil with brush by iron plate, then the filament cut is placed on wipe oil iron plate on, dry 5-15 minute, smash into smalls to pieces stand-by;
4. Radix Angelicae Pubescentis, Herba Lophatheri, Herba Epimedii, Semen Coicis, Fructus Forsythiae, Herba Hedyotidis Diffusae and the Radix Astragali are together placed in crock, decoct with water twice, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoct 50-70 minute, twice filtrate merges, and leaves standstill 3-5 hour, obtains supernatant;
5. by step 4. gained supernatant burn heat, add after boiling Indigo Naturalis and step 1.-3. gained smalls, decoct and stir, take out during one-tenth paste to be mixed, thick paste is dried 30-50 minute, obtain drying object, drying object is dry at 70-90 DEG C, both obtained according to every part of 10g subpackage.
5. the preparation method of Chinese medicine composition according to claim 4, is characterized in that: 1. step adds the hot water of 75-85 DEG C, instills Oleum sesami (preferred, to add the hot water of 80 DEG C, instill Oleum sesami after 30 minutes) after 25-35 minute.
6. the preparation method of Chinese medicine composition according to claim 4, is characterized in that: 2. step sprays evenly with the yellow wine burning heat, stewing 4-5 hour (preferred, spray evenly with the yellow wine burning heat, stewing 4.5 hours).
7. the preparation method of Chinese medicine composition according to claim 4, is characterized in that: 2. the Chinese crude drug cooked is placed in rapidly in pot by step, parch 8-10 minute (preferred, to be placed in rapidly in pot by the Chinese crude drug cooked, parch 9 minutes).
8. the preparation method of Chinese medicine composition according to claim 4, it is characterized in that: 3. the filament cut is placed on and wipes on oily iron plate by step, dry 8-13 minute (preferred, the filament cut to be placed on and to wipe on oily iron plate, dry 10 minutes).
9. the preparation method of Chinese medicine composition according to claim 4, it is characterized in that: step 4. twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoct 55-65 minute (preferred, twice decoction is all that first big fire is fried open, after larding speech with literary allusions decoction 60 minutes).
10. the preparation method of Chinese medicine composition according to claim 4, is characterized in that: 5. thick paste is dried 35-45 minute by step, obtains drying object, drying object is dry (preferred at 75-85 DEG C, thick paste is dried 40 minutes, obtain drying object, drying object is dry at 80 DEG C).
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