CN104547464A - Traditional Chinese medicine decoction for treating upper respiratory infection and preparation method of traditional Chinese medicine decoction - Google Patents

Traditional Chinese medicine decoction for treating upper respiratory infection and preparation method of traditional Chinese medicine decoction Download PDF

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CN104547464A
CN104547464A CN201510032624.6A CN201510032624A CN104547464A CN 104547464 A CN104547464 A CN 104547464A CN 201510032624 A CN201510032624 A CN 201510032624A CN 104547464 A CN104547464 A CN 104547464A
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张会云
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Abstract

The invention discloses a traditional Chinese medicine decoction for treating upper respiratory infection. The traditional Chinese medicine decoction is prepared from the following main raw materials in parts by weight: 5-15 parts of hydrocotyle asiatica, 10-20 parts of honeysuckle, 3-9 parts of radix bupleuri, 2-6 parts of isatis roots, 1-5 parts of andrographis paniculata, 3-8 parts of radix scrophulariae, 1-5 parts of acacia catechu, 3-8 parts of radix angelicae pubescentis, 1-5 parts of borneol, 2-6 parts of oyster, 1-5 parts of angelica dahurica, 3-8 parts of solidago decurrens, 10-20 parts of green onion and 8-15 parts of cactus. The traditional Chinese medicine decoction is easy in obtaining of medicinal sources and low in cost, and the medicinal materials are generally substances with gentle medicinal property, so that economic or body burden is not caused to users in long-term use.

Description

A kind of Chinese medicine decoction and preparation method for the treatment of upper respiratory tract infection
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine decoction and preparation method for the treatment of upper respiratory tract infection.
Background technology
Upper respiratory tract infection is called for short upper sense, also known as common cold.It is the general name comprising nasal cavity, pharynx or acute throat inflammation.The upper sense of broad sense is not a medical diagnosis on disease, but one group of disease, comprise common cold, viral pharyngitis, laryngitis, herpangina, pharyngoconjunctival fever, bacterial pharyngotonsillitis.The upper sense of narrow sense, also known as common cold, is modal acute infections of respiratory tract disease, and how in self limiting, but incidence rate is higher.Adult is annual to be occurred 2 ~ 4 times, and child's incidence rate is higher, annual 6 ~ 8 times.The whole year all can fall ill, and winter-spring season is more.
The cause of disease: upper respiratory tract infection has 70% ~ 80% to be caused by virus.Comprise rhinovirus, coronavirus, adenovirus, influenza and parainfluenza virus, respiratory syncytial virus, echovirus, Coxsackie virus etc.The upper sense of 20% ~ 30% is separately had to be caused by antibacterial.Bacteriological infection can direct infection or after being secondary to viral infection, be the most common with Hemolytic streptococcus, being secondly hemophilus influenza, streptococcus pneumoniae, staphylococcus etc., is occasionally gram-negative bacteria.The various reason causing whole body or respiratory tract local defense function to reduce, as suffered from cold, drenching with rain, abrupt change of climate, overtired etc. can make former virus that is that be present in upper respiratory tract or that invade from the external world or antibacterial breed rapidly, thus bring out primary disease.Old germling is weak, immunologic hypofunction or suffer from the patient susceptible of chronic respiratory tract disease.
Clinical manifestation: according to the difference of the cause of disease and extent of disease, clinical manifestation can have different types: 1. common cold: be commonly called as " cold ", also known as acute rhinitis or common cold, how to be caused by rhinovirus, secondly cause for coronavirus, parainfluenza virus, respiratory syncytial virus, echovirus, Coxsackie virus etc.Onset is comparatively anxious, and 1 ~ 3 day incubation period, not etc. different with virus, enterovirus was not shorter, and adenovirus, respiratory syncytial virus etc. are longer.Main manifestations is sniffle, as sneeze, nasal obstruction, stream clear water sample nasal mucus, also can show as cough, dry pharynx, itching throat or burning sensation, even Postnasal drip sense.Morbidity can have the symptoms such as sneeze, nasal obstruction, stream clear water sample nasal mucus simultaneously or after a few hours.Nasal mucus retrogradation after 2 ~ 3 days, often accompanies pharyngalgia, sheds tears, hypogeusia, hypopnea, hoarseness etc.General without heating and General Symptoms, or only have low grade fever, discomfort, slight fear of cold, headache.The visible bronchia mucosal hyperemia of health check-up, edema, there is secretions, pharyngeal mild hyperaemia.The symptoms such as auditory dysesthesia can be had during concurrent salpingitis.Purulent sputum or serious lower respiratory tract symptom point out the viral infection beyond merging rhinovirus or secondary bacterial sexuality to contaminate.As without complication, within 5 ~ 7 days, can fully recover.2. acute viral pharyngitis or laryngitis: (1) acute viral pharyngitis is many to be caused by rhinovirus, adenovirus, influenza virus, parainfluenza virus and enterovirus, respiratory syncytial virus etc.Clinical symptoms is pharyngeal itching or burning sensation, and cough rare, pharyngalgia is not obvious.When swallowing pain, normal prompting has streptococcal infection.Can have when influenza virus and adenovirus infection heating and weak.Adenovirus pharyngitis can be scorching with eye binding film.The pharyngeal obvious congestion and edema of health check-up, submandibular lymph nodes enlargement and touch a tender spot.(2) acute viral laryngitis is many is caused by rhinovirus, influenza A virus, parainfluenza virus and adenovirus etc.Pain when Clinical symptoms is hoarseness, difficulty speaking, cough, often has heating, pharyngalgia or cough.The visible laryngeal edema of health check-up, hyperemia, regional nodes's silght enlargement and tenderness, the sound of stridulating of audible and throat.3. acute herpetic angina: often caused by CA, show as obvious pharyngalgia, heating, the course of disease about 1 week, more than summer attack, child is common, occasionally in adult.The visible pharyngeal hyperemia of health check-up, there are canescence herpes and shallow table ulcer in soft palate, uvula, pharynx and tonsil surface, have blush around, form herpes later.4. pharyngoconjunctival fever: cause primarily of adenovirus, Coxsackie virus etc.Clinical manifestation has heating, pharyngalgia, photophobia, sheds tears, health check-up swallow as seen and binding film obviously congested.The course of disease 4 ~ 6 days, often betide summer, child is common, and swimmer is easy to propagate.5. bacterial pharyngotonsillitis: many by Hemolytic streptococcus, secondly causes for hemophilus influenza, streptococcus pneumoniae, staphylococcus etc.Onset is anxious, obviously pharyngalgia, fear of cold, heating (body temperature can reach more than 39 DEG C).The visible pharyngeal obvious hyperemia of health check-up, antiadoncus, hyperemia, there is yellow purulent secretion on surface, submandibular lymph nodes enlargement, tenderness, pulmonary's absence of signs.
In the Chinese medicine of existing treatment upper respiratory tract infection, Authorization Notice No. CN 102416098 B (application number 201110402566.3) patent document discloses a kind of powder for the treatment of upper respiratory tract infection, it is characterized in that, it is made up by following method of following bulk drugs: extracting honeysuckle 80 grams, Radix Tinosporae 150 grams, Fructus Forsythiae 250 grams, 150 grams, Radix Glycyrrhizae, euphorbiae fischerianae 150 grams, Rhizoma Chuanxiong 100 grams, Lagotis clarkei Hook. F (Lagotis brevituba Maxim.) 200 grams, Radix Ophiopogonis 150 grams, Fructus Schisandrae Chinensis 80 grams, Herba Senecionis Scandentis 150 and the Radix Astragali 80 grams, pulverize, cross 100 mesh sieves, then lactose 150 grams and 250 grams, mannitol is added, mixing, in loading 100 bags and get final product.Authorization Notice No. CN 103142733 B (application number 201310091439.5) patent document discloses a kind of Chinese medicine composition for the treatment of upper respiratory tract infection, it is characterized in that being made up of following raw material medicaments: Herba Senecionis Scandentis 50 parts, Caulis Fibraureae 40 parts, the little plumage moss of spire 40 parts, Fructus Forsythiae 40 parts, large fruit bar halberd 30 parts, Flos Chrysanthemi 30 parts, Herba Andrographis 20 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 20 parts, Radix Platycodonis 12 parts, Borneolum Syntheticum 9 parts.
As can be seen here, Chinese medicine occupies the status of very Chinese medicine in treatment upper respiratory tract infection, but in patent documentation, is not specifically designed to aftertreatment upper respiratory tract infection, bactericidal antiphlogistic, the medicine of relieving cough and resolving phlegm.
Summary of the invention
For the deficiencies in the prior art, an object of the present invention is to provide a kind of Chinese medicine decoction for the treatment of upper respiratory tract infection, and medical material medicine source of the present invention is easy to get, with low cost, selected medical material mostly be mild in medicine property and thing, life-time service also can not increase the burden on economy and health to user.
Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicine decoction.
Technical scheme of the present invention is:
Treat a Chinese medicine decoction for upper respiratory tract infection, take off the primary raw material stating weight proportion and be prepared from: Herba Centellae 5-15 part, Flos Lonicerae 10-20 part, Radix Bupleuri 3-9 part, Radix Isatidis 2-6 part, Herba Andrographis 1-5 part, Radix Scrophulariae 3-8 part, catechu 1-5 part, Radix Angelicae Pubescentis 3-8 part, Borneolum Syntheticum 1-5 part, Concha Ostreae 2-6 part, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 1-5 part, Herba Solidaginis 3-8 part, Herba Alii fistulosi 10-20 part, Radix et Caulis Opuntiae Dillenii 8-15 part.
Treat a Chinese medicine decoction for upper respiratory tract infection, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Herba Centellae 8-13 part, Flos Lonicerae 13-18 part, Radix Bupleuri 5-7 part, Radix Isatidis 3-5 part, Herba Andrographis 2-4 part, Radix Scrophulariae 4-7 part, catechu 2-4 part, Radix Angelicae Pubescentis 4-7 part, Borneolum Syntheticum 2-4 part, Concha Ostreae 3-5 part, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 2-4 part, Herba Solidaginis 4-7 part, Herba Alii fistulosi 13-18 part, Radix et Caulis Opuntiae Dillenii 10-13 part.
Treat a Chinese medicine decoction for upper respiratory tract infection, more preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Herba Centellae 10 parts, Flos Lonicerae 15 parts, Radix Bupleuri 6 parts, Radix Isatidis 4 parts, Herba Andrographis 3 parts, Radix Scrophulariae 5.5 parts, 3 parts, catechu, Radix Angelicae Pubescentis 5.5 parts, Borneolum Syntheticum 3 parts, Concha Ostreae 4 parts, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 3 parts, Herba Solidaginis 5 parts, Herba Alii fistulosi 15 parts, Radix et Caulis Opuntiae Dillenii 11 parts.
The preparation method of above-mentioned Chinese medicine decoction, step is as follows:
(1) Radix Scrophulariae, Radix Angelicae Pubescentis and Radix Angelicae Dahuricae (Radix Heraclei Scabridi) are placed in container and clean with hairbrush, be placed in white vinegar, be put on iron plate, on smokeless stove fire, dry 8-14 minute after soaking completely, it is stand-by to grind to form smalls after cooling;
(2) Herba Alii fistulosi and Radix et Caulis Opuntiae Dillenii are cleaned, are cut into silk, be ground into thick paste with the slender roll of medicated paper or gauze, be placed in and burn in hot dry pot, with little fire parch 5-15 minute repeatedly, repeatedly will stir by the large ferrum spoon of use gently in the process of frying, dry in the air cool stand-by;
(3) Concha Ostreae is even with yellow wine spray, stewing 24-48 hour, be placed on tile, little fire dries 5-15 minute slowly, grinds to form smalls, crosses 80-120 mesh sieve;
(4) by Herba Centellae, Flos Lonicerae, Radix Bupleuri and Radix Isatidis with 80-100 DEG C of hot-water soak to room temperature, water consumption is 4-8 times of crude drug gross weight, big fire decocts to boiling, clean Herba Andrographis, catechu, Borneolum Syntheticum and Herba Solidaginis is added after 5 minutes until boiling, little fire simmers 30-90 minute slowly, change big fire and decoct 1-5 minute, cease fire and leave standstill 5-10 hour, get supernatant stand-by;
(5) step (4) gained supernatant is placed on smokeless stove fire, little fire is decocted slowly to boiling and is added step (1)-(3) gained smalls, decoct with chopsticks while be stirred to and melt completely, cool, obtain Chinese medicine decoction.
The preparation method of above-mentioned Chinese medicine decoction, step (1) is dried 10-12 minute (preferred, to dry 11 minutes on smokeless stove fire) on smokeless stove fire.
The preparation method of above-mentioned Chinese medicine decoction, step (2) is with little fire parch 8-13 minute repeatedly (preferred, with the parch 10 minutes repeatedly of little fire).
The preparation method of above-mentioned Chinese medicine decoction, step (3) boils in a covered pot over a slow fire 32-40 hour, is placed on tile, and little fire dries 8-13 minute (preferred, stewing 36 hours, be placed on tile, little fire dried 10 minutes slowly) slowly.
The preparation method of above-mentioned Chinese medicine decoction, step (4) by Herba Centellae, Flos Lonicerae, Radix Bupleuri and Radix Isatidis with 85-95 DEG C of hot-water soak to room temperature (preferred, by Herba Centellae, Flos Lonicerae, Radix Bupleuri and Radix Isatidis with 90 DEG C of hot-water soaks to room temperature).
The preparation method of above-mentioned Chinese medicine decoction, step (4) water consumption is the 5-7 of crude drug gross weight doubly (preferred, water consumption is 6 times of crude drug gross weight).
The preparation method of above-mentioned Chinese medicine decoction, step (4) little fire simmers 50-70 minute slowly, changes big fire and decocts 2-4 minute, ceases fire and leaves standstill 6-9 hour (preferred, little fire simmers 60 minutes slowly, changes big fire and decocts 3 minutes, ceases fire and leaves standstill 8 hours).
Best using method: be the therapeutic effect making the present invention reach best, the Chinese medicine decoction made, is divided into 2 parts, morning, noon and afternoon each portion, white sugar of adding some points that can be suitable according to the taste of individual, and 3 days is a course for the treatment of.
The pharmacological effect of each crude drug is respectively:
Herba Centellae: base is former: be dry herb or the whole herb with root of dicotyledon Umbelliferae Herba Centellae.Composition: containing the Triterpenoid of multiple α-balsam alcohol type, wherein have asiaticoside, thankuniside, isothankuniside, asiaticoside, Brahmoside, broken hot rice glycosides and Brahmic acid etc., and madasiatic acid.The property of medicine: bitter, acrid, cold.Return liver,spleen,kidney warp.Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis and reducing edema.Be the long-lived medicine of Asians, can refresh oneself by beneficial brain.Research shows to have nourishing, antiinflammatory, healing of wound, diuresis relieving constipation and calm effect.Also effective in cure to leprosy, ulcer, there is activation to blood purification and immunity, because it can stimulate the replacement of deep skin cell.It is neural nourishing agent, can improve memory, alleviate mental fatigue; Also can blood pressure lowering, treatment hepatopathy etc.
Flos Lonicerae: Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times.Its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, and for various febrile disease, as fever of the body, dermexanthesis, send out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, Flos Lonicerae is just extensive and famous with its medical value since ancient times.Its effect mainly heat-clearing and toxic substances removing, cures mainly epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furunculosis etc.Modern study proves, Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, stronger restraint is had to the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc., in addition also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, can be used for the treatment of respiratory tract infection, bacillary dysentery, acute urinary, hypertension etc. more than 40 with other medicines compatibility and plant disease.
Radix Bupleuri: Radix Bupleuri is conventional diaphoretic medicine.Another name ground smoke, mountain dish, mushroom grass, faggot, nature and flavor hardship, be slightly cold, return liver, gallbladder meridian.There is reconciling superficies and interior, effect of soothing the liver yang invigorating.For cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterine prolapse, menoxenia.
Radix Isatidis: nature and flavor are bitter, cold.3 return through GUIXIN, stomach warp.4 effect heat-clearing and toxic substances removing, removing heat from blood, sore-throat relieving.5 cure mainly pestilence seasonal noxious pathogen, heating pharyngalgia, maculae caused by violent heat pathogen, mumps, scarlet fever, major part pestilence, erysipelas, carbuncle.
Herba Andrographis: have heat-clearing and toxic substances removing, antiinflammatory, reducing swelling and alleviating pain effect.Andrographolide, neoandrographolide all have the effect suppressing and delay Diplococcus pneumoniae and the rising of the body temperature caused by hemolytic group B streptococcus, and the action intensity of the latter is not as good as the former.For the rabbit or 2 generated heat caused by TAB, the rat of the caused heating of 4--dinitrophenol,DNP, deoxyandrographolide, andrographolide, new Herba Andrographis, lactone, dehydrorographolide all have certain refrigeration function, wherein the strongest with dehydrorographolide effect.With deoxyandrographolide and neoandrographolide suspendible intraperitoneal injection, to while subcutaneous injection Diplococcus pneumoniae and Hemolytic streptococcus culture caused by fever in rabbit can postpone the body temperature rise time, weaken body temperature rising degree.
Radix Scrophulariae: effect clearing away heat and cooling blood; Nourishing YIN to lower pathogenic fire; Detoxicating and resolving stagnation of pathogens 5 cures mainly warm febrile disease and nutrient blood; Fever of the body; Excessive thirst; Crimson tongue; Send out speckle; Hectic fever due to YIN-deficiency chronic cough; Fidgets due to deficiency is awake not; Constipation is hindered in Tianjin; Order is puckery dim-sighted; Throat larynx swells and ache; Scrofula sucutaneous nodule; Skin sore.
Catechu: heartwood fragment decocts juice, be catechu extractum or catechu end through concentrate drying, have heat clearing away, promote the production of body fluid, reduce phlegm, stop blooding, sore, granulation promoting, the function such as analgesic therapy.The mimosa extract extracted from heartwood is also the good raw material of industrial tanning, dyestuff.Timber is hard, careful, can for sleeper, building, farm implements, compartment etc.Resisting pathogenic microbes effect: extracorporeal bacteria inhibitor test shows, the minimum inhibitory concentration (MIC) of catechu is 2.81mg/ml to staphylococcus aureus, Staphylococcus albus is 5.63mg/ml, beta hemolytic streptococcus is 5.63mg/ml, candida albicans is 5.63mg/ml, also once reports that catechu was to bacillus pyocyaneus, diphtheria corynebacterium, Bacillus proteus.Dysentery bacterium, Bacillus typhi etc. have inhibitory action.The catechu suspension of 5% is to being 100% to the Sensitivity rate of Fu Shi and Boydii dysentery bacterium in the drug sensitive test of 68 strain dysentery bacteriums.In addition remarkable inhibitory action is also had to virus and some fungus.
Radix Angelicae Pubescentis: be the root of the heavy tooth Radix Angelicae Sinensis of Umbelliferae archangel.Composition: containing coumarin kind compound, volatile oil, acetas, angelol, thymol.Pharmacology: play a very important role to cardiovascular system, has the effect of blood pressure lowering, can promote hematoblastic gathering, have good analgesia and antiinflammatory action.There is anti-light quick effect, have significant curative effect to opposing tumor, anti-inflammation is also played a very important role.The property of medicine: bitter, tepor, pungent.Return kidney, urinary bladder channel.Function cures mainly: expelling wind and dampness, dispersing cold for relieving pain.
Borneolum Syntheticum: bitter, is slightly cold; GUIXIN, liver, lung meridian; Delicate fragrance a surname is loose, has refreshment of having one's ideas straightened out, and the loose poison of heat clearing away, effect of improving acuity of vision and removing nebula, cures mainly calentura unconsciousness due to high fever, apoplexy syncope due to accumulation of phlegm infantile convulsion, and heat-damp in summer hoodwinks key clearly, and sore throat is deaf, and aphtha tooth swells, carbuncle sore infantile malnutrition hemorrhoid, conjunctival congestion and swelling pain, pterygium.
Concha Ostreae: meridian distribution of property and flavor: salty, is slightly cold; Return liver, gallbladder, kidney channel.Function: medicine for calming liver and calming endopathic wind; Yin-nourishing drug.Concha Ostreae (calcined): the effect restraining astringent or styptic treatment for spontaneous sweating deacidification is strong, treatment has a stomach-ache, gastric acid etc.Concha Ostreae: above accept and hold back, treatment is dizzy, just rare.There are convergence, calmness, removing toxic substances, analgesic effect; The acidic extraction thing of Concha Ostreae is inhibited to poliovirus in live body, and the Mus mortality rate of infection is reduced.
Radix Angelicae Dahuricae (Radix Heraclei Scabridi): base is former: be the root of Umbelliferae archangel Angelica dahurica.Composition: root is containing Coumarins: gloomy Byakangelicol, 7-demethyl cork Pericarpium Zanthoxyli, Byakangelicol, byak-angelicin, imperatorin, different imperatorin, oxypeucedanin, phellopterin etc.The property of medicine: pungent, bitter, temperature.Function cures mainly: expelling pathogenic wind from the body surface, removing damp and stopping pain.Cure mainly flu, headache, toothache, rheumatic arthralgia.
Herba Solidaginis: base is former: be herb or the root of Compositae Herba Solidaginis platymiscium Herba Solidaginis.Composition: aerial parts is containing saponin component: Herba Solidaginis glycosides, activities of Solidago virgaurea L saponin 3 that is 3, Solidago saponin, solidago canadesis saponin, huge Herba Solidaginis saponin, the triterpene glycosides etc. of Polygalacic acid.The property of medicine: pungent, bitter, cool.Function cures mainly: wind and heat dispersing, removing toxic substances and promoting subsidence of swelling.Cure mainly anemopyretic cold, laryngopharynx swelling and pain, cough due to lung-heat, jaundice, pyretic stranguria, carbuncle furuncle, venom, traumatic injury.
Herba Alii fistulosi: another name and thing grass, onion, dish primary, HUOCONG, the four seasons Herba Alii fistulosi.Flavor efficacy is pungent, and temperature, enters lung, stomach warp.Exterior-excess hollow, rise to fall more and lack, merit is specially dispersed and is activated yang, can expelling wind and cold pathogens, and diaphoresis expelling pathogenic factors from muscles, is used for the treatment of the mild of typhoid fever, cold and heat headache; Again can item, sharp key, relieving constipation, activate yang gas and loose YIN-cold, be used for the treatment of QI and blood cohesion, dizzy headache, QI stagnated by cold, abdominal distention is suffered from abdominal pain, and bladder qi dysfunction and dysuria etc.; In addition still tool removing toxic substances, hemostatic function.Energy activating yang to invigorate blood circulation, anthelmintic removing toxic substances, relieving the exterior syndrome by diaphoresis.Cure mainly the diseases such as anemofrigid cold mild, carbuncle sore tumefacting virus, dysentery faint pulse, cold coagulation stomachache, dysuria, have good therapeutical effect to flu, wind and cold, headache, YIN-cold stomachache, malnutrition due to parasitic infestation internal resistance, dysentery etc.
Radix et Caulis Opuntiae Dillenii: promoting flow of QI and blood, heat-clearing and toxic substances removing.Control heart peratodynia, mass in the abdomen, dysentery, hemorrhoidal bleeding, cough, laryngalgia, lung abscess, acute mastitis, furuncle, burn, snakebite.
Chinese medicine decoction of the present invention " more holistic ", both upper respiratory tract infection can be treated, again can be antibacterial, this is the large feature being different from Drug therapy, crude drug of the present invention, by have antibacterial, bring down a fever, cough-relieving is together with having the drug regimen for the treatment of upper respiratory tract infection effect, serve effect for the treatment of upper respiratory tract infection, and this Chinese medicine decoction is prepared from according to Chinese medicine principle completely, more safe and reliable, without any side effects, to matrix without any stimulation.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 one kinds treats the Chinese medicine decoction of upper respiratory tract infection, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Herba Centellae 5 parts, Flos Lonicerae 10 parts, Radix Bupleuri 3 parts, Radix Isatidis 2 parts, Herba Andrographis 1 part, Radix Scrophulariae 3 parts, 1 part, catechu, Radix Angelicae Pubescentis 3 parts, Borneolum Syntheticum 1 part, Concha Ostreae 2 parts, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 1 part, Herba Solidaginis 3 parts, Herba Alii fistulosi 10 parts, Radix et Caulis Opuntiae Dillenii 8 parts.
The preparation method of above-mentioned Chinese medicine decoction, preparation process is as follows:
(1) Radix Scrophulariae, Radix Angelicae Pubescentis and Radix Angelicae Dahuricae (Radix Heraclei Scabridi) are placed in container and clean with hairbrush, be placed in white vinegar, be put on iron plate after soaking completely, dry 8 minutes on smokeless stove fire, it is stand-by to grind to form smalls after cooling;
(2) Herba Alii fistulosi and Radix et Caulis Opuntiae Dillenii are cleaned, are cut into silk, be ground into thick paste with the slender roll of medicated paper or gauze, be placed in burn heat dry pot in, with the parch 5 minutes repeatedly of little fire, repeatedly to stir by the large ferrum spoon of use gently in the process of frying, dry in the air cool stand-by;
(3) Concha Ostreae is even with yellow wine spray, stewing 24 hours, be placed on tile, little fire dried 5 minutes slowly, grinds to form smalls, crossed 80 mesh sieves:
(4) by Herba Centellae, Flos Lonicerae, Radix Bupleuri and Radix Isatidis with 80 DEG C of hot-water soaks to room temperature, water consumption is 4 times of crude drug gross weight, big fire decocts to boiling, clean Herba Andrographis, catechu, Borneolum Syntheticum and Herba Solidaginis is added after 5 minutes until boiling, little fire simmers 30 minutes slowly, change big fire and decoct 1 minute, cease fire and leave standstill 5 hours, get supernatant stand-by;
(5) step (4) gained supernatant is placed on smokeless stove fire, little fire is decocted slowly to boiling and is added step (1)-(3) gained smalls, decoct with chopsticks while be stirred to and melt completely, cool, obtain Chinese medicine decoction.
Model case one: king XX, man, 29 years old is the workman of Jinan factory, and autumn in 2013, patient examined, and watery nasal discharge, low grade fever 2 days, acutely cough, and without god in sensation eye, large dry stool is secret, yellowish or reddish urine.Remove examination in hospital, hyperpyrexia, temperature is 38.2 DEG C, and pharyngeal cavity is slightly red and swollen, both sides antiadoncus, and slightly congested, dry cough is frequent, and two pulmonary respiration sounds are clear, red tongue, yellow and thin fur, and floating and rapid pulse is held concurrently sliding real, is diagnosed as respiratory tract infection.
Use the present embodiment 1 gained Chinese medicine decoction, take 1 day, symptom is improved greatly, sensation spiritedness, the fever is down, continues again to take 3 days, and all diseases disappear substantially, not rhinorrhea, and also do not coughed, continue again to take embodiment 4 gained Chinese medicine decoction 3 days, disease obtains recovery from illness.
Embodiment 2 one kinds treats the Chinese medicine decoction of upper respiratory tract infection, takes off the primary raw material stating weight proportion and is prepared from (getting 5g for every part): Herba Centellae 15 parts, Flos Lonicerae 20 parts, Radix Bupleuri 9 parts, Radix Isatidis 6 parts, Herba Andrographis 5 parts, Radix Scrophulariae 8 parts, 5 parts, catechu, Radix Angelicae Pubescentis 8 parts, Borneolum Syntheticum 5 parts, Concha Ostreae 6 parts, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 5 parts, Herba Solidaginis 8 parts, Herba Alii fistulosi 20 parts, Radix et Caulis Opuntiae Dillenii 15 parts.
The preparation method of above-mentioned Chinese medicine decoction, preparation process is as follows:
(1) Radix Scrophulariae, Radix Angelicae Pubescentis and Radix Angelicae Dahuricae (Radix Heraclei Scabridi) are placed in container and clean with hairbrush, be placed in white vinegar, be put on iron plate after soaking completely, dry 14 minutes on smokeless stove fire, it is stand-by to grind to form smalls after cooling;
(2) Herba Alii fistulosi and Radix et Caulis Opuntiae Dillenii are cleaned, are cut into silk, be ground into thick paste with the slender roll of medicated paper or gauze, be placed in burn heat dry pot in, with the parch 15 minutes repeatedly of little fire, repeatedly to stir by the large ferrum spoon of use gently in the process of frying, dry in the air cool stand-by;
(3) Concha Ostreae is even with yellow wine spray, stewing 48 hours, be placed on tile, little fire dried 15 minutes slowly, grinds to form smalls, crossed 80-120 mesh sieve;
(4) by Herba Centellae, Flos Lonicerae, Radix Bupleuri and Radix Isatidis with 100 DEG C of hot-water soaks to room temperature, water consumption is 8 times of crude drug gross weight, big fire decocts to boiling, clean Herba Andrographis, catechu, Borneolum Syntheticum and Herba Solidaginis is added after 5 minutes until boiling, little fire simmers 90 minutes slowly, change big fire and decoct 5 minutes, cease fire and leave standstill 10 hours, get supernatant stand-by;
(5) step (4) gained supernatant is placed on smokeless stove fire, little fire is decocted slowly to boiling and is added step (1)-(3) gained smalls, decoct with chopsticks while be stirred to and melt completely, cool, obtain Chinese medicine decoction.
Model case two: woods XX, female, 17 years old.Jinan, Shandong Province personage, the pupil of certain primary school, generates heat suddenly time at school, and teacher sees that it is uncomfortable, patient is with to go to Hospital to check immediately, take temperature, temperature 39 DEG C, doctor thinks it is simple heating, just open the medicine of bringing down a fever to it, after 2 days there is the symptom of cough, abundant expectoration in patient, and expectorant color white matter is rare, gurgling with sputum, food of receiving still can, two just still adjust, uneasy sleeping at night, light red tongue, tongue is greasy in vain, the above-mentioned symptom that when going large hospital inspection to find, upper respiratory tract infection causes, under the suggestion of doctor, starts to take gained Chinese medicine decoction of the present invention.
Use the present embodiment 2 gained Chinese medicine decoction, after taking 1 day, temperature recovery is normal, take 5 days, do not coughed, appetite increases, all diseases disappear all, peace of sleeping night and, diet, two is just all normal, recovery from illness, after patient's recovery from illness, bought again one bottle for subsequent use, whenever doing not feel like oneself and influenza virus is serious, be just used for preventing respiratory tract infection disease.
Embodiment 3 one kinds treats the Chinese medicine decoction of upper respiratory tract infection, takes off the primary raw material stating weight proportion and is prepared from (getting 15g for every part): Herba Centellae 8 parts, Flos Lonicerae 13 parts, Radix Bupleuri 5 parts, Radix Isatidis 3 parts, Herba Andrographis 2 parts, Radix Scrophulariae 4 parts, 2 parts, catechu, Radix Angelicae Pubescentis 4 parts, Borneolum Syntheticum 2 parts, Concha Ostreae 3 parts, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 2 parts, Herba Solidaginis 4 parts, Herba Alii fistulosi 13 parts, Radix et Caulis Opuntiae Dillenii 10 parts.
The preparation method of above-mentioned Chinese medicine decoction, preparation process is as follows:
(1) Radix Scrophulariae, Radix Angelicae Pubescentis and Radix Angelicae Dahuricae (Radix Heraclei Scabridi) are placed in container and clean with hairbrush, be placed in white vinegar, be put on iron plate after soaking completely, dry 10 minutes on smokeless stove fire, it is stand-by to grind to form smalls after cooling;
(2) Herba Alii fistulosi and Radix et Caulis Opuntiae Dillenii are cleaned, are cut into silk, be ground into thick paste with the slender roll of medicated paper or gauze, be placed in burn heat dry pot in, with the parch 8 minutes repeatedly of little fire, repeatedly to stir by the large ferrum spoon of use gently in the process of frying, dry in the air cool stand-by;
(3) Concha Ostreae is even with yellow wine spray, stewing 30 hours, be placed on tile, little fire dried 8 minutes slowly, grinds to form smalls, crossed 90 mesh sieves;
(4) by Herba Centellae, Flos Lonicerae, Radix Bupleuri and Radix Isatidis with 85 DEG C of hot-water soaks to room temperature, water consumption is 5 times of crude drug gross weight, big fire decocts to boiling, clean Herba Andrographis, catechu, Borneolum Syntheticum and Herba Solidaginis is added after 5 minutes until boiling, little fire simmers 50 minutes slowly, change big fire and decoct 3 minutes, cease fire and leave standstill 6 hours, get supernatant stand-by;
(5) step (4) gained supernatant is placed on smokeless stove fire, little fire is decocted slowly to boiling and is added step (1)-(3) gained smalls, decoct with chopsticks while be stirred to and melt completely, cool, obtain Chinese medicine decoction.
Embodiment 4 one kinds treats the Chinese medicine decoction of upper respiratory tract infection, takes off the primary raw material stating weight proportion and is prepared from (getting 20g for every part): Herba Centellae 13 parts, Flos Lonicerae 18 parts, Radix Bupleuri 7 parts, Radix Isatidis 5 parts, Herba Andrographis 4 parts, Radix Scrophulariae 7 parts, 4 parts, catechu, Radix Angelicae Pubescentis 7 parts, Borneolum Syntheticum 4 parts, Concha Ostreae 5 parts, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 4 parts, Herba Solidaginis 7 parts, Herba Alii fistulosi 18 parts, Radix et Caulis Opuntiae Dillenii 13 parts.
The preparation method of above-mentioned Chinese medicine decoction, preparation process is as follows:
(1) Radix Scrophulariae, Radix Angelicae Pubescentis and Radix Angelicae Dahuricae (Radix Heraclei Scabridi) are placed in container and clean with hairbrush, be placed in white vinegar, be put on iron plate after soaking completely, dry 12 minutes on smokeless stove fire, it is stand-by to grind to form smalls after cooling;
(2) Herba Alii fistulosi and Radix et Caulis Opuntiae Dillenii are cleaned, are cut into silk, be ground into thick paste with the slender roll of medicated paper or gauze, be placed in burn heat dry pot in, with the parch 13 minutes repeatedly of little fire, repeatedly to stir by the large ferrum spoon of use gently in the process of frying, dry in the air cool stand-by;
(3) Concha Ostreae is even with yellow wine spray, stewing 40 hours, be placed on tile, little fire dried 13 minutes slowly, grinds to form smalls, crossed 110 mesh sieves;
(4) by Herba Centellae, Flos Lonicerae, Radix Bupleuri and Radix Isatidis with 80-100 DEG C of hot-water soak to room temperature, water consumption is 7 times of crude drug gross weight, big fire decocts to boiling, clean Herba Andrographis, catechu, Borneolum Syntheticum and Herba Solidaginis is added after 5 minutes until boiling, little fire simmers 70 minutes slowly, change big fire and decoct 4 minutes, cease fire and leave standstill 9 hours, get supernatant stand-by;
(5) step (4) gained supernatant is placed on smokeless stove fire, little fire is decocted slowly to boiling and is added step (1)-(3) gained smalls, decoct with chopsticks while be stirred to and melt completely, cool, obtain Chinese medicine decoction.
Embodiment 5 one kinds treats the Chinese medicine decoction of upper respiratory tract infection, takes off the primary raw material stating weight proportion and is prepared from (getting 30g for every part): Herba Centellae 10 parts, Flos Lonicerae 15 parts, Radix Bupleuri 6 parts, Radix Isatidis 4 parts, Herba Andrographis 3 parts, Radix Scrophulariae 5.5 parts, 3 parts, catechu, Radix Angelicae Pubescentis 5.5 parts, Borneolum Syntheticum 3 parts, Concha Ostreae 4 parts, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 3 parts, Herba Solidaginis 5 parts, Herba Alii fistulosi 15 parts, Radix et Caulis Opuntiae Dillenii 11 parts.
The preparation method of above-mentioned Chinese medicine decoction, preparation process is as follows:
(1) Radix Scrophulariae, Radix Angelicae Pubescentis and Radix Angelicae Dahuricae (Radix Heraclei Scabridi) are placed in container and clean with hairbrush, be placed in white vinegar, be put on iron plate after soaking completely, dry 11 minutes on smokeless stove fire, it is stand-by to grind to form smalls after cooling;
(2) Herba Alii fistulosi and Radix et Caulis Opuntiae Dillenii are cleaned, are cut into silk, be ground into thick paste with the slender roll of medicated paper or gauze, be placed in burn heat dry pot in, with the parch 10 minutes repeatedly of little fire, repeatedly to stir by the large ferrum spoon of use gently in the process of frying, dry in the air cool stand-by;
(3) Concha Ostreae is even with yellow wine spray, stewing 36 hours, be placed on tile, little fire dried 10 minutes slowly, grinds to form smalls, crossed 100 mesh sieves;
(4) by Herba Centellae, Flos Lonicerae, Radix Bupleuri and Radix Isatidis with 90 DEG C of hot-water soaks to room temperature, water consumption is 6 times of crude drug gross weight, big fire decocts to boiling, clean Herba Andrographis, catechu, Borneolum Syntheticum and Herba Solidaginis is added after 5 minutes until boiling, little fire simmers 60 minutes slowly, change big fire and decoct 3 minutes, cease fire and leave standstill 8 hours, get supernatant stand-by;
(5) step (4) gained supernatant is placed on smokeless stove fire, little fire is decocted slowly to boiling and is added step (1)-(3) gained smalls, decoct with chopsticks while be stirred to and melt completely, cool, obtain Chinese medicine decoction.
The clinical practice of the Chinese medicine decoction of test example 1 embodiment 5 gained treatment upper respiratory tract infection: in January ,-2014 in January, 2012,400 routine patients are screened in 4 hospitals, before test 1 week, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups, experimental group and matched group at random, experimental group uses embodiment 5 products obtained therefrom, and matched group uses other medicine.Curative effect situation criterion: cure: malaise symptoms disappears, effective: after using this product, malaise symptoms disappears; Invalid: after using this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1: use embodiment 5 gained Chinese medicine decoction compliance test result
Therapeutic effect: cure 160 examples (80%), effective 36 (18%), invalid 4 examples (2%), total effective rate 98%, successful is better than matched group.And invalid in 4 people use after a period of time in continuation, malaise symptoms also all makes moderate progress, and does not therefore get rid of and makes result deviation to some extent because service time is short.Between the operating period, there is malaise symptoms or side effect in no one.
Between the operating period self-induction symptom and physical change of spirit as shown in table 2.
Table 2:
As shown in Table 2: use 3 days, patient's malaise symptoms of 55% improves, and cough alleviates; Use 6 days, patient's malaise symptoms of more than 74% improves gradually or disappears, and self-induction is fully recovered; Use 9 days, patient's malaise symptoms of more than 96% fades away, recovery from illness.

Claims (10)

1. treat a Chinese medicine decoction for upper respiratory tract infection, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Herba Centellae 5-15 part, Flos Lonicerae 10-20 part, Radix Bupleuri 3-9 part, Radix Isatidis 2-6 part, Herba Andrographis 1-5 part, Radix Scrophulariae 3-8 part, catechu 1-5 part, Radix Angelicae Pubescentis 3-8 part, Borneolum Syntheticum 1-5 part, Concha Ostreae 2-6 part, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 1-5 part, Herba Solidaginis 3-8 part, Herba Alii fistulosi 10-20 part, Radix et Caulis Opuntiae Dillenii 8-15 part.
2. the Chinese medicine decoction for the treatment of upper respiratory tract infection according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Herba Centellae 8-13 part, Flos Lonicerae 13-18 part, Radix Bupleuri 5-7 part, Radix Isatidis 3-5 part, Herba Andrographis 2-4 part, Radix Scrophulariae 4-7 part, catechu 2-4 part, Radix Angelicae Pubescentis 4-7 part, Borneolum Syntheticum 2-4 part, Concha Ostreae 3-5 part, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 2-4 part, Herba Solidaginis 4-7 part, Herba Alii fistulosi 13-18 part, Radix et Caulis Opuntiae Dillenii 10-13 part.
3. the Chinese medicine decoction for the treatment of upper respiratory tract infection according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Herba Centellae 10 parts, Flos Lonicerae 15 parts, Radix Bupleuri 6 parts, Radix Isatidis 4 parts, Herba Andrographis 3 parts, Radix Scrophulariae 5.5 parts, 3 parts, catechu, Radix Angelicae Pubescentis 5.5 parts, Borneolum Syntheticum 3 parts, Concha Ostreae 4 parts, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 3 parts, Herba Solidaginis 5 parts, Herba Alii fistulosi 15 parts, Radix et Caulis Opuntiae Dillenii 11 parts.
4. the preparation method of the Chinese medicine decoction according to any one of claim 1-3, is characterized in that: step is as follows:
(1) Radix Scrophulariae, Radix Angelicae Pubescentis and Radix Angelicae Dahuricae (Radix Heraclei Scabridi) are placed in container and clean with hairbrush, be placed in white vinegar, be put on iron plate, on smokeless stove fire, dry 8-14 minute after soaking completely, it is stand-by to grind to form smalls after cooling;
(2) Herba Alii fistulosi and Radix et Caulis Opuntiae Dillenii are cleaned, are cut into silk, be ground into thick paste with the slender roll of medicated paper or gauze, be placed in and burn in hot dry pot, with little fire parch 5-15 minute repeatedly, repeatedly will stir by the large ferrum spoon of use gently in the process of frying, dry in the air cool stand-by;
(3) Concha Ostreae is even with yellow wine spray, stewing 24-48 hour, be placed on tile, little fire dries 5-15 minute slowly, grinds to form smalls, crosses 80-120 mesh sieve;
(4) by Herba Centellae, Flos Lonicerae, Radix Bupleuri and Radix Isatidis with 80-100 DEG C of hot-water soak to room temperature, water consumption is 4-8 times of crude drug gross weight, big fire decocts to boiling, clean Herba Andrographis, catechu, Borneolum Syntheticum and Herba Solidaginis is added after 5 minutes until boiling, little fire simmers 30-90 minute slowly, change big fire and decoct 1-5 minute, cease fire and leave standstill 5-10 hour, get supernatant stand-by;
(5) step (4) gained supernatant is placed on smokeless stove fire, little fire is decocted slowly to boiling and is added step (1)-(3) gained smalls, decoct with chopsticks while be stirred to and melt completely, cool, obtain Chinese medicine decoction.
5. the preparation method of Chinese medicine decoction according to claim 4, is characterized in that: step (1) is dried 10-12 minute (preferred, to dry 11 minutes on smokeless stove fire) on smokeless stove fire.
6. the preparation method of Chinese medicine decoction according to claim 4, is characterized in that: step (2) is with little fire parch 8-13 minute repeatedly (preferred, with the parch 10 minutes repeatedly of little fire).
7. the preparation method of Chinese medicine decoction according to claim 4, is characterized in that: step (3) boils in a covered pot over a slow fire 32-40 hour, is placed on tile, little fire dries 8-13 minute (preferably slowly, stewing 36 hours, be placed on tile, little fire dried 10 minutes slowly).
8. the preparation method of Chinese medicine decoction according to claim 4, it is characterized in that: step (4) by Herba Centellae, Flos Lonicerae, Radix Bupleuri and Radix Isatidis 85-95 DEG C hot-water soak to room temperature (preferred, by Herba Centellae, Flos Lonicerae, Radix Bupleuri and Radix Isatidis with 90 DEG C of hot-water soaks to room temperature).
9. the preparation method of Chinese medicine decoction according to claim 4, is characterized in that: step (4) water consumption is the 5-7 of crude drug gross weight doubly (preferred, water consumption is 6 times of crude drug gross weight).
10. the preparation method of Chinese medicine decoction according to claim 4; it is characterized in that: step (4) little fire simmers 50-70 minute slowly; change big fire and decoct 2-4 minute; ceasing fire, it is (preferred to leave standstill 6-9 hour; little fire simmers 60 minutes slowly; change big fire and decoct 3 minutes, cease fire and leave standstill 8 hours).
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